Genetic associations between modifiable risk factors and Alzheimer disease
JAMA Network Open
About The Study: This genetic association study including 39,000 participants with clinically diagnosed Alzheimer disease (AD) and 401,000 control participants without AD found novel genetic associations between high high-density lipoprotein (HDL) cholesterol concentrations and high systolic blood pressure with higher risk of AD. These findings may inspire new drug targeting and improved prevention implementation.
Authors: Ruth Frikke-Schmidt, M.D., D.M.Sc., Ph.D., of Copenhagen University Hospital–Rigshospitalet in Copenhagen, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2023.13734)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.13734?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051723
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
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Authors: Ruth Frikke-Schmidt, M.D., D.M.Sc., Ph.D., of Copenhagen University Hospital–Rigshospitalet in Copenhagen, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2023.13734)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.13734?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=051723
About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
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