PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Diagnosis of type 1 diabetes after SARS-CoV-2 infection: Researchers find possible correlation

2023-05-23
(Press-News.org) Different studies have documented an increased incidence of type 1 diabetes during the COVID-19 pandemic. However, none of the studies distinguishes between children with and without SARS-CoV-2 infection. Researchers were now able to gain new insights: the KVB data set provides information on whether children diagnosed with type 1 diabetes previously had COVID-19. This allows an analysis of the temporal relationship between a COVID-19 diagnosis and the diagnosis of type 1 diabetes. Amongst the analyzed children without type 1 diabetes diagnosis before the start of the pandemic, 16.6 percent had a diagnosis of COVID-19 between January 2020 and December 2021.

SARS-CoV-2 infection was associated with an increased risk of type 1 diabetes in children

The researchers’ initial findings were consistent with data from Germany and other countries: the incidence rate of type 1 diabetes in children between the ages of 2 and 12 years was around 50 percent higher in the years 2020 to 2021 as compared to the incidence rate in 2018 to 2019. Important and novel, they found that the development of type 1 diabetes in 2020 to 2021 was higher in the children with COVID-19. The likelihood to develop type 1 diabetes was increased by 57 percent in children who had a confirmed SARS-CoV-2 infection compared to non-infected children. The increase in type 1 diabetes incidence occurred in the same quarter as the COVID-19 diagnosis and also in later quarters.

The new data point to a direct effect of SARS-CoV-2 infection on the development of type 1 diabetes

“We are cautious in our interpretation, but the findings suggest that the virus could either promote initiation of the underlying autoimmunity in type 1 diabetes or accelerate the progression of the disease in children with existing autoimmunity," says Ezio Bonifacio, last author of the study. Further studies will be needed, to elucidate the exact mechanism driving the increased incidence of type 1 diabetes during the COVID-19 pandemic in young children.

Further studies planned

The team of researchers also has access to cohorts of prospectively followed children from the Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) and the Fr1da Study. “We want to look into these cohorts to see whether the development of islet autoantibodies and/or type 1 diabetes was increased in the children after SARS-CoV-2 infection,” says Anette-Gabriele Ziegler, Director of the Helmholtz Munich Institute of Diabetes Research and GPPAD researcher. The findings of these studies will help to determine whether vaccination against COVID-19 should be considered in children at risk for type 1 diabetes.

END


ELSE PRESS RELEASES FROM THIS DATE:

RPI and Albany Medical College researchers awarded $3.3 million to improve breast cancer treatment using artificial intelligence

RPI and Albany Medical College researchers awarded $3.3 million to improve breast cancer treatment using artificial intelligence
2023-05-23
Researchers from Rensselaer Polytechnic Institute (RPI) and Albany Medical College were awarded a $3.3 million grant over five years by the National Cancer Institute to use artificial intelligence (AI) to improve targeted drug therapy in HER2-positive breast cancer treatment. HER2-positive breast cancer tends to grow and spread quickly, but targeted treatments improve outcomes. The research is being led by Xavier Intes, Rensselaer professor of biomedical engineering and co-director of the Center for Modeling, Simulation and Imaging in Medicine, and ...

Element creation in the lab deepens understanding of surface explosions on neutron stars

Element creation in the lab deepens understanding of surface explosions on neutron stars
2023-05-23
Led by Kelly Chipps of the Department of Energy’s Oak Ridge National Laboratory, scientists working in the lab have produced a signature nuclear reaction that occurs on the surface of a neutron star gobbling mass from a companion star. Their achievement improves understanding of stellar processes generating diverse nuclear isotopes. “Neutron stars are really fascinating from the points of view of both nuclear physics and astrophysics,” said ORNL nuclear astrophysicist Kelly Chipps, who led a study published in Physical Review Letters. “A deeper understanding of their dynamics may help reveal the cosmic ...

New treatment helps people stop addictive opioid painkillers used for chronic pain

2023-05-23
Programme of combined one-to-one and group support sessions was tested in landmark clinical trial After one year, one in five people were able to stop taking opioids without their pain increasing Experts say the new treatment is an alternative to opioid use and has potential to give patients better quality of life Researchers at the University of Warwick and The James Cook University Hospital, Middlesbrough have led a clinical trial, funded by the National Institute for Health and Care Research (NIHR), on a new treatment which can help people stop needing to use opioid painkillers to manage chronic pain. There are over 1 ...

CT scan best at predicting heart disease risk in middle age

2023-05-23
CHICAGO ---CT scans are better at predicting a middle-aged person’s risk for a heart disease, such as a heart attack, than genetics, reports a new Northwestern Medicine study.  “Finding the best way to identify who is at risk for developing heart disease can help determine what needs to be done to lower their risk,” said lead study author Dr. Sadiya Khan, an assistant professor of medicine and preventive medicine at Northwestern University Feinberg School of Medicine and a Northwestern Medicine cardiologist. “This finding can help doctors and patients in managing risk for heart disease, which is the leading cause ...

Study: Transcatheter mitral valve repair safe, successful

Study: Transcatheter mitral valve repair safe, successful
2023-05-23
Long-awaited outcomes data of transcatheter edge-to-edge procedures to repair patients’ leaky mitral valves revealed the minimally invasive procedure to be safe and effective in nearly 90% of patients, according to Cedars-Sinai physician-scientists. Their findings on the condition called degenerative mitral regurgitation were published today in the peer-reviewed Journal of the American Medical Association (JAMA), representing the largest study to date that examines outcomes for patients treated outside of a clinical trial with transcatheter edge-to-edge repair (TEER). “Treatment was successful in nearly nine out of every 10 patients in whom TEER was used to repair ...

Artificial pancreas reduces disease management burden for people with diabetes

Artificial pancreas reduces disease management burden for people with diabetes
2023-05-23
WASHINGTON, May 23, 2023 – Type 1 diabetes affects 46.3 million people worldwide, and the number of people affected increases by about 3% each year. It requires careful calculations of insulin needs and bothersome daily injections to avoid peripheral diseases caused by extremes of high or low blood sugar. Automated insulin delivery systems, also called artificial pancreases, make diabetes management much less onerous for patients. These systems — with implanted insulin sensors, pumps that ...

Electronic noses sniff out volatile organic compounds

Electronic noses sniff out volatile organic compounds
2023-05-23
WASHINGTON, May 23, 2023 – Volatile organic compounds are chemicals emitted as gases that can have adverse health effects. They are often found in paints, pharmaceuticals, and refrigerants, among other common products, but they can also act as markers of explosives, insect infestation, food spoilage, and disease. Tracing VOCs is important for public safety and all “smell” related issues. To this end, in Applied Physics Reviews, from AIP Publishing, Liu et al. introduced a fluid mechanics-based chamber design for an electronic nose (e-nose) that consistently detects ...

Neighborhood income mobility and risk of neonatal and maternal morbidity

2023-05-23
bout The Study: In this study of women living in low-income areas, those who moved to a higher-income area between births experienced less morbidity and death in their second pregnancy, as did their newborns, compared with those who remained in low-income areas between births. Research is needed to determine whether financial incentives or enhancement of neighborhood factors can reduce adverse maternal and perinatal outcomes.  Authors: Joel G. Ray, M.D., M.Sc., of the University of Toronto, is the corresponding author.   To ...

Factors associated with protection from SARS-CoV-2 Omicron variant infection and disease among vaccinated health care workers

2023-05-23
About The Study: Immunoglobin G and neutralizing antibody titer levels were associated with protection against infection with the Omicron variant and against symptomatic disease in this study that included 2,300 vaccinated health care workers in Israel.  Authors: Gili Regev-Yochay, M.D., of the Sheba Medical Center in Ramat Gan, Israel, is the corresponding author.   To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2023.14757) Editor’s ...

Prediabetes and fracture risk among midlife women

2023-05-23
About The Study: The findings in this study of nearly 1,700 midlife women without diabetes suggest that prediabetes was associated with risk of fracture. Future research should determine whether treating prediabetes reduces fracture risk.  Authors: Albert Shieh, M.D., of the David Geffen School of Medicine at University of California, Los Angeles, is the corresponding author.   To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2023.14835) Editor’s ...

LAST 30 PRESS RELEASES:

Danforth Plant Science Center adds two new faculty members

Robotic eyes mimic human vision for superfast response to extreme lighting

Racial inequities and access to COVID-19 treatment

Residential segregation and lung cancer risk in African American adults

Scientists wipe out aggressive brain cancer tumors by targeting cellular ‘motors’

Capturability distinction analysis of continuous and pulsed guidance laws

CHEST expands Bridging Specialties Initiative to include NTM disease and bronchiectasis on World Bronchiectasis Day

Exposure to air pollution may cause heart damage

SwRI, UTSA selected by NASA to test electrolyzer technology aboard parabolic flight

Prebiotics might be a factor in preventing or treating issues caused by low brain GABA

Youngest in class at higher risk of mental health problems

American Heart Association announces new volunteer leaders for 2025-26

Gut microbiota analysis can help catch gestational diabetes

FAU’s Paulina DeVito awarded prestigious NSF Graduate Research Fellowship

Champions for change – Paid time off initiative just made clinical trials participation easier

Fentanyl detection through packaging

Prof. Eran Meshorer elected to EMBO for pioneering work in epigenetics

New 3D glacier visualizations provide insights into a hotter Earth

Creativity across disciplines

Consequences of low Antarctic sea ice

Hear here: How loudness and acoustic cues help us judge where a speaker is facing

A unique method of rare-earth recycling can strengthen the raw material independence of Europe and America

Epilepsy self-management program shows promise to control seizures, improve mood and quality of life

Fat may play an important role in brain metabolism

New study finds no lasting impact of pandemic pet ownership on human well-being

New insights on genetic damage of some chemotherapies could guide future treatments with less harmful side effects

Gut microbes could protect us from toxic ‘forever chemicals’

Novel modelling links sea ice loss to Antarctic ice shelf calving events

Scientists can tell how fast you're aging from a single brain scan

U.S. uterine cancer incidence and mortality rates expected to significantly increase by 2050

[Press-News.org] Diagnosis of type 1 diabetes after SARS-CoV-2 infection: Researchers find possible correlation