(Press-News.org) Research Highlights:
An analysis of more than 202,000 heart attack deaths between 2015-2020 in a single Chinese province found that days that had extreme heat, extreme cold or high levels of fine particulate matter (PM2.5) air pollution were significantly associated with the risk of death from a heart attack, especially in women and older adults.
The greatest increase in the risk of death from heart attack was seen on days that had the combination of extreme heat and high levels of PM2.5.
The days with extreme heat were associated with an increased risk of heart attack death in women vs. men, and in older adults than in younger adults. Older adults were also at a greater risk of heart attacks compared to younger adults during days with extreme cold or high levels of PM2.5.
Embargoed until 1 p.m. CT/2 p.m. ET Monday, July 24, 2023
DALLAS, July 24, 2023 — The combination of soaring heat and smothering fine particulate pollution may double the risk of heart attack death, according to a new study of more than 202,000 heart attack deaths in China. The study published today in the American Heart Association’s flagship journal Circulation.
“Extreme temperature events are becoming more frequent, longer and more intense, and their adverse health effects have drawn growing concern. Another environmental issue worldwide is the presence of fine particulate matter in the air, which may interact synergistically with extreme temperatures to adversely affect cardiovascular health,” said senior author Yuewei Liu, M.D., Ph.D., an associate professor of epidemiology in the School of Public Health at Sun Yat-sen University in Guangzhou, China. “However, it remains unknown if and how co-exposure to extreme temperatures and fine particulate pollution might interact to trigger a greater risk of death from heart attack, which is an acute response potentially brought on by an acute scenario and a great public health challenge due to its substantial disease burden worldwide.”
To examine the impact of extreme temperatures with and without high levels of fine particulate pollution, the researchers analyzed 202,678 heart attack deaths between 2015-2020 that occurred in Jiangsu province, a region with four distinct seasons and a wide range of temperatures and fine particulate pollution levels. The deaths were among older adults with an average age of 77.6 years; 52% were older than age 80; and 52% were male. Particulate exposure on the day of each death and one day before death were included in the analysis.
Extreme temperatures were gauged according to the daily heat index (also referred to as apparent temperature) for an area, which captures the combined effect of both heat and humidity. Both the length and extremeness of heat waves and cold snaps were evaluated. Heart attack deaths, or case days, during these periods were compared with control days on the same day of the week in the same month — meaning that if a death occurred on a Wednesday, all other Wednesdays in the same month would be considered control days. Particulate levels were considered high on any day with an average level of fine particulate matter above 37.5 micrograms per cubic meter.
“Our findings provide evidence that reducing exposure to both extreme temperatures and fine particulate pollution may be useful to prevent premature deaths from heart attack, especially for women and older adults,” Liu said.
Compared with control days, the risk of a fatal heart attack was observed at the following levels:
18% higher during 2-day heat waves with heat indexes at or above the 90th percentile (ranging from 82.6 to 97.9 degrees Fahrenheit), increasing with temperature and duration, and was 74% higher during 4-day heat waves with heat indexes at or above the 97.5th percentile (ranging from 94.8 to 109.4 degrees Fahrenheit). For context, 6,417 (3.2%) of the 202,678 observed deaths from heart attack happened during heat waves with heat indexes at or above the 95th percentile (ranging from 91.2 to 104.7 degrees Fahrenheit) for three or more days.
4% higher during 2-day cold snaps with temperatures at or below the 10th percentile (ranging from 33.3 to 40.5 degrees Fahrenheit), increasing with lower temperatures and duration, and was 12% higher during 3-day cold snaps with temperatures at or below the 2.5th percentile (ranging from 27.0 to 37.2 degrees Fahrenheit). For context, 6,331 (3.1%) of the 202,678 observed deaths from heart attack happened during cold spells with temperatures at or below the 5th percentile (ranging from 30.0 to 38.5 degrees Fahrenheit) for 3 or more days.
Twice as high during 4-day heat waves that had fine particulate pollution above 37.5 micrograms per cubic meter. Days with high levels of fine particulate pollution during cold snaps did not have an equivalent increase in the risk of heart attack death.
Generally higher among women than men during heat waves.
Higher among people ages 80 and older than in younger adults during heat waves, cold snaps or days with high levels of fine particulate pollution.
The mean age of all individuals who died from a heart attack in Jiangsu from 2015-2020, including during non-extreme temperature events, was 77.6 years old; 52.1% of these individuals were over 80 years old.
The researchers estimated that up to 2.8% of heart attack deaths may be attributed to the combination of extreme temperatures and high levels of fine particulate pollution (> 37.5 micrograms per cubic meter), according to WHO targets.
“Strategies for individuals to avoid negative health effects from extreme temperatures include following weather forecasts, staying inside when temperatures are extreme, using fans and air conditioners during hot weather, dressing appropriately for the weather, proper hydration and installing window blinds to reduce indoor temperatures,” said Liu. “Using an air purifier in the house, wearing a mask outdoors, staying clear of busy highways when walking and choosing less-strenuous outdoor activities may also help to reduce exposure to air pollution on days with high levels of fine particulate pollution. To improve public health, it is important to take fine particulate pollution into consideration when providing extreme temperature warnings to the public.”
In a 2020 scientific statement and a 2020 policy statement, the American Heart Association details the latest science about air pollution exposure and the individual, industrial and policy measures to reduce the negative impact of poor air quality on cardiovascular health. Reducing exposure to air pollution and reversing the negative impact of poor air quality on cardiovascular health, including heart disease and stroke, is essential to reducing health inequities in Black and Hispanic communities, those that have been historically marginalized and under-resourced, and communities that have the highest levels of exposure to air pollution.
The investigators recommended additional research about the possible interactive effects of extreme weather events and fine particulate pollution on heart attack deaths in areas with different temperature and pollution ranges to confirm their findings. The study did not include adjustments for any adaptive behaviors taken by individuals, such as using air conditioning and staying indoors, when temperatures are extreme or pollution levels are high, which could cause misclassification of individuals’ exposure to weather and alter their risk patterns. These results also may not be generalizable to other regions in China or other countries due to potential variations of adaption capacity and temperature distribution.
Background:
Fine particulates are less than 2.5 microns in size and may be inhaled deep into the lungs, where they can irritate the lungs and blood vessels around the heart. Most are associated with fuel combustion, such as particles from car exhaust, factory emissions or wildfires.
Previous research has confirmed that exposure to particulate matter including fine particulates is linked to heart disease, stroke and other health issues.
For context, the World Health Organization’s target for average annual exposure to fine particulate pollution level is no more than 5 micrograms per cubic meter and no more than 15 micrograms per cubic meter for more than 3-4 days per year.
In this study, heat waves were defined as periods at or above the 90th, 92.5th, 95th and 97.5th percentiles of daily heat indexes (ranging from 82.6 to 109.4 degrees Fahrenheit across Jiangsu province, China) for at least 2, 3 or 4 consecutive days.
Cold spells were defined as periods at or below the 10th, 7.5th, 5th, 2.5th percentiles of daily heat indexes (ranging from 27 to 40.5 degrees Fahrenheit) for at least 2, 3 or 4 consecutive days.
Co-authors and authors’ disclosures are listed in the manuscript. This study was funded by China’s Ministry of Science and Technology.
Statements and conclusions of studies published in the American Heart Association’s scientific journals are solely those of the study authors and do not necessarily reflect the Association’s policy or position. The Association makes no representation or guarantee as to their accuracy or reliability. The Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and biotech companies, device manufacturers and health insurance providers and the Association’s overall financial information are available here.
Additional Resources:
Multimedia is available on right column of release link
After July 24, 2023, view the manuscript online.
AHA news release: Extremely hot and cold days linked to cardiovascular deaths (December 2022)
AHA news release: Personal protection and public policy change can decrease health impact of pollution (Nov. 2020)
Follow AHA/ASA news on Twitter @HeartNews
Follow news from the AHA’s flagship journal Circulation @CircAHA
About the American Heart Association
The American Heart Association is a relentless force for a world of longer, healthier lives. We are dedicated to ensuring equitable health in all communities. Through collaboration with numerous organizations, and powered by millions of volunteers, we fund innovative research, advocate for the public’s health and share lifesaving resources. The Dallas-based organization has been a leading source of health information for nearly a century. Connect with us on heart.org, Facebook, Twitter or by calling 1-800-AHA-USA1.
###
END
Risk of fatal heart attack may double in heat wave & high fine particulate pollution days
Heat waves, cold snaps and high levels of fine particulate pollution could raise heart attack risk; however, the most dangerous combination is heat and fine particulate pollution, according to a new study published in Circulation
2023-07-24
ELSE PRESS RELEASES FROM THIS DATE:
Study shows positive outcomes for first three U.S. living HIV-to-HIV kidney transplant donors
2023-07-24
Based on findings from a study published today in the journal, The Lancet Regional Health – Americas, researchers at Johns Hopkins Medicine and three collaborating medical institutions suggest that people living with the human immunodeficiency virus (HIV) who donate a kidney to other people living with HIV (PLWH) have a low risk of developing end-stage kidney disease (ESKD) or other kidney problems in the years following the donation.
“This new evidence is proof-of-concept that donating a kidney can be safe for people living with HIV,” says Christine Durand, M.D., associate professor of medicine at Johns ...
Webb detects water vapor in rocky planet-forming zone
2023-07-24
Water is essential for life as we know it. However, scientists debate how it reached the Earth and whether the same processes could seed rocky exoplanets orbiting distant stars. New insights may come from the planetary system PDS 70, located 370 light-years away. The star hosts both an inner disk and outer disk of gas and dust, separated by a 5 billion-mile-wide (8 billion kilometer) gap, and within that gap are two known gas-giant planets.
New measurements by NASA’s James Webb Space Telescope’s MIRI (Mid-Infrared Instrument) have detected water vapor in the system’s inner disk, at distances ...
Diagnosis of cystic fibrosis often missed or delayed, especially in non-White infants
2023-07-24
Ann & Robert H. Lurie Children’s Hospital of Chicago is leading an awareness campaign that aims to reduce missed or delayed diagnosis of cystic fibrosis after newborn screening, especially in non-White infants. In its first phase, the campaign targets primary care providers and public health officials, so that treatment can start earlier, which is linked to better outcomes for people with cystic fibrosis. The general public phase is expected to follow within the year.
Funded by the Centers for Disease Control and Prevention ...
Potent anti-cancer therapy created using ‘click chemistry’
2023-07-24
A potent anti-cancer therapy has been created using Nobel prize-winning “click chemistry”, where molecules click together like LEGO bricks, in a new study by UCL and Stanford University researchers.
The study, published in Nature Chemistry, opens up new possibilities for how cutting-edge cancer immunotherapies might be built in future.
The research team created an anti-cancer therapy with three components: one targeting the cancer cell, another recruiting a white blood cell called a T cell to attack the cancer cell, and a third knocking out part of the cancer cell’s defences.
Previously, ...
Claire K. Ankuda, MD, MPH (Mount Sinai Health System) recognized with AFAR 2023 Rising Star Award in Health Services and Aging Research
2023-07-24
New York, NY – The American Federation for Aging Research (AFAR), a national non-profit organization whose mission is to support and advance healthy aging through biomedical research, is proud to recognize the outstanding contributions of Claire K. Ankuda, MD, MPH, MSc with the 2023 Terrie Fox Wetle Rising Star Award in Health Services and Aging Research.
This award honors a health services researcher in an early or middle phase of his/her career who has already made important contributions with work that respects the value of multidisciplinary health services ...
Ming Xu, PhD (UConn) receives AFAR 2023 Vincent Cristofalo Rising Star Award in Aging Research
2023-07-24
New York, NY – The American Federation for Aging Research (AFAR), a national non-profit organization whose mission is to support and advance healthy aging through biomedical research, is pleased to recognize the exemplary contributions of Ming Xu, PhD, to the field of aging research through the 2023 Vincent Cristofalo Rising Star Award in Aging Research.
This award is named in honor of the late Dr. Cristofalo, who dedicated his career to aging research and to encouraging young scientists to investigate important problems in the biology of aging. Established in 2008, the award is a ...
NIH researcher Rafael de Cabo, PhD receives AFAR 2023 Irving S. Wright Award of Distinction
2023-07-24
The American Federation for Aging Research (AFAR), a national non-profit organization whose mission is to support and advance healthy aging through biomedical research, is pleased to recognize the exemplary contributions of Rafael de Cabo, PhD, to the field of aging research through the 2023 Irving S. Wright Award of Distinction.
This award is named in honor of AFAR’s founder and recognizes exceptional contributions to basic or clinical research in the field of aging. Established in 1982, the award is a framed citation and carries a cash prize of $5,000.
Dr. de Cabo is Senior Investigator of the ...
Muscadine wine shows promise in improving aging skin
2023-07-24
Could muscadine wine help perk up sagging skin? According to a new study, women who drank two glasses of dealcoholized muscadine wine daily showed significant improvements in the elasticity and water retention of their skin compared with those who consumed a placebo.
The study is the first time scientists have studied the impacts of nonalcoholic wine consumption on skin health in a randomized clinical trial. Researchers attribute the beneficial effects to chemical compounds called polyphenols that naturally occur in many plants.
“Muscadine grapes have been found to have a unique polyphenolic profile in comparison to other red wine varieties,” ...
Study explores how often children diagnosed with flu experience serious neuropsychiatric side effects
2023-07-24
While the incidence of influenza-associated neuropsychiatric events in children in the United States is unknown, the controversy over the use of a common antiviral medication typically administered to treat flu in children has sparked concern among parents and medical professionals alike.
The dilemma about whether the treatment causes neuropsychiatric events or if the infection itself is the culprit, led a group of pediatric researchers at Monroe Carell Jr. Children’s Hospital at Vanderbilt to study the question.
“Population-Based ...
Hebrew SeniorLife and Duke University receive $10.5 million award to study osteoporosis care in fracture patients
2023-07-24
Broken bones in later life are a leading cause of disability, recurrent fracture, nursing home placement, and death.
Prior studies have shown that health care providers can prevent poor outcomes, including death, by treating patients with bone-strengthening medications and by stopping risky medications that cause falls. However, few patients receive this high-quality care because it is time consuming and requires specialized knowledge that primary care providers may not have.
Researchers from Hebrew SeniorLife and Duke University will undertake a 5.5-year study that will compare two care models that have previously ...
LAST 30 PRESS RELEASES:
Multi-resistance in bacteria predicted by AI model
Tinker Tots: A citizen science project to explore ethical dilemmas in embryo selection
Sensing sickness
Cost to build multifamily housing in California more than twice as high as in Texas
Program takes aim at drinking, unsafe sex, and sexual assault on college campuses
Inability to pay for healthcare reaches record high in U.S.
Science ‘storytelling’ urgently needed amid climate and biodiversity crisis
KAIST Develops Retinal Therapy to Restore Lost Vision
Adipocyte-hepatocyte signaling mechanism uncovered in endoplasmic reticulum stress response
Mammals were adapting from life in the trees to living on the ground before dinosaur-killing asteroid
Low LDL cholesterol levels linked to reduced risk of dementia
Thickening of the eye’s retina associated with greater risk and severity of postoperative delirium in older patients
Almost one in ten people surveyed report having been harmed by the NHS in the last three years
Enhancing light control with complex frequency excitations
New research finds novel drug target for acute myeloid leukemia, bringing hope for cancer patients
New insight into factors associated with a common disease among dogs and humans
Illuminating single atoms for sustainable propylene production
New study finds Rocky Mountain snow contamination
Study examines lactation in critically ill patients
UVA Engineering Dean Jennifer West earns AIMBE’s 2025 Pierre Galletti Award
Doubling down on metasurfaces
New Cedars-Sinai study shows how specialized diet can improve gut disorders
Making moves and hitting the breaks: Owl journeys surprise researchers in western Montana
PKU Scientists simulate the origin and evolution of the North Atlantic Oscillation
ICRAFT breakthrough: Unlocking A20’s dual role in cancer immunotherapy
How VR technology is changing the game for Alzheimer’s disease
A borrowed bacterial gene allowed some marine diatoms to live on a seaweed diet
Balance between two competing nerve proteins deters symptoms of autism in mice
Use of antifungals in agriculture may increase resistance in an infectious yeast
Awareness grows of cancer risk from alcohol consumption, survey finds
[Press-News.org] Risk of fatal heart attack may double in heat wave & high fine particulate pollution daysHeat waves, cold snaps and high levels of fine particulate pollution could raise heart attack risk; however, the most dangerous combination is heat and fine particulate pollution, according to a new study published in Circulation