(Press-News.org) About The Study: The findings of this exploratory study suggest there are racial disparities in dementia severity, functional impairment, and neuropsychiatric symptoms. Future work must address racial disparities and their underlying determinants as well as the lack of representation of racially minoritized individuals in nationally representative dementia registries.
Authors: Lauren Massimo, Ph.D., of the University of Pennsylvania in Philadelphia, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamaneurol.2023.3093)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamaneurology/fullarticle/10.1001/jamaneurol.2023.3093?guestAccessKey=22b848ae-d0db-4fc6-a1c5-1dad83e7ba01&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=091123
END
Racial differences in clinical presentation in individuals diagnosed with frontotemporal dementia
JAMA Neurology
2023-09-11
ELSE PRESS RELEASES FROM THIS DATE:
Use of tenofovir alafenamide fumarate for HIV pre-exposure prophylaxis and incidence of hypertension, initiation of statins
2023-09-11
About The Study: In this study of people taking pre-exposure prophylaxis (PrEP) for HIV, tenofovir alafenamide fumarate (TAF) use was found to be associated with higher incident hypertension and statin initiation compared with tenofovir disoproxil fumarate use, especially in those 40 years or older. Continued monitoring of blood pressure and lipids for TAF users is warranted.
Authors: Adovich S. Rivera, M.D., Ph.D., of Kaiser Permanente Southern California in Pasadena, is the corresponding author.
To access the embargoed study: Visit our For The ...
Discovery of protein-protein interaction lays foundation for future glioblastoma therapy
2023-09-11
The discovery of a previously unknown molecular target has inspired what may become a therapeutic breakthrough for people with glioblastoma, the most common and aggressive brain cancer.
When people hear the word “cancer” they often picture a single mass, but glioblastoma cells are also highly invasive and spread quickly from the central mass, making it very difficult to fully eradicate. Even with current treatments such as temozolomide, the standard chemotherapy approved to treat glioblastoma, ...
The human lipidome reveals new indicators of health, disease and aging
2023-09-11
The sequencing of the human genome promised a revolution in medicine, but scientists soon realized that a genetic blueprint alone does not show the body in action. That required understanding the proteome – all the proteins, expressed by our genes, forming the cellular machinery that performs the bulk of the body’s functions. Now, another set of molecules known as the lipidome – all the lipids in our bodies – is filling in more details of human physiology.
Lipids are a broad category of small, fatty or oily molecules, including triglycerides, cholesterol, hormones ...
Auxin signaling pathway controls root hair formation for nitrogen uptake
2023-09-11
Plants have evolved diverse adaptive strategies to optimize the exploration of light and soil resources from their environments. One of the most prominent adaptive responses is the developmental plasticity of their root systems, which enables plants to efficiently forage nutrient pools that fluctuate in space and time. As a crucial component determining the active root surface, root hairs represent a powerful morphological trait to improve water and nutrient acquisition. Root hairs are extensions of epidermal cells that effectively enlarge the root surface area and facilitate soil exploration for water and nutrients. Root hair development starts with cell fate specification, which ...
Hobbies linked to lower depression levels among older people
2023-09-11
Having a hobby is linked to fewer depressive symptoms and higher levels of happiness, self-reported health and life satisfaction among people aged 65 and over, and this holds true across 16 countries on three continents, according to a new study led by UCL (University College London) researchers.
The study, published in the journal Nature Medicine, aimed to see if the benefits of hobbies were consistent in different national settings, and looked at data from 93,263 people aged 65 or over who had enrolled in five existing longitudinal studies in England, Japan, United States, China and 12 European countries.
Analysing data from participants spanning four to eight ...
Higher breast cancer risk after certain forms of childhood cancer treatment
2023-09-11
Women who have been treated for cancer as a child with a certain type of chemotherapy have an increased risk of breast cancer, according to a large-scale international study of survivors of childhood cancer led by scientists from the Princess Máxima Center for pediatric oncology. The results were published today, 11 September, in the leading journal Nature Medicine and point to the need for earlier breast cancer screening in women who have previously been treated with this chemotherapy and radiation for childhood cancer.
Three out of four children with cancer are successfully treated ...
Super antifreeze in cells: The ability to survive in ice and snow developed in animals far earlier than we thought
2023-09-11
The globe was hot and humid. The sea was teeming with life. Early squids, eel-like fish and sea worms hunted smaller animals. Above ground, however, nothing stirred. The animals had not yet crawled ashore.
That was what the Earth looked like about 450 million years ago at the end of the Ordovicium period.
The warm water created the perfect living conditions for wildlife. But this would soon change. Shortly after, the land masses would began to freeze and an ice cap start to spread.
The water, which had ...
The important connectivity of metal oxides with hydrogen
2023-09-11
Understanding the interactions between materials and chemical species is critical for engineers as it helps them determine their best uses for both day-to-day life and global-level applications.
Metal oxides, a binary material of metal and oxygen, greatly interest researchers because of their importance in transforming energy storage, production, and conversion. To further those possibilities, a team from the University of Pittsburgh Swanson School of Engineering has determined a new way to view how hydrogen and metal oxides interact.
“Numerous experimental techniques have been used to understand this phenomenon – from spectroscopy to catalysis” explained Giannis ...
ETH Zurich chooses Symplectic Grant Tracker to promote world-class research
2023-09-11
Digital Science, a technology company serving stakeholders across the research ecosystem, is pleased to announce that ETH Zurich has chosen Symplectic Grant Tracker from Digital Science’s suite of flagship products to power its internal funding program, to promote world-class research with the potential to result in fundamental new knowledge or technologies and exciting discoveries.
Designed from the outset to meet research funding needs, Grant Tracker includes features to assist applicants, reviewers, committees and funders and help them to work efficiently and effectively across the grants management lifecycle.
The ETH Zurich Research ...
Cancer-causing mutations rewire growth signalling in prostate cancer model
2023-09-11
Key points:
The PIP3/PI3K signalling pathway is one of the most important signalling mechanisms in our cells, affecting cell metabolism and growth. It is also one of the most frequently altered pathways in human cancer.
Research from the Institute has shown that PI3K pathway remodelling is a common feature of cancers driven by hyperactivated PI3K signalling. Working in prostate tumour models the team identified an unknown activator driving PI3K signalling and cancer growth in a way that is released both from needing positive growth signals and also from growth-limiting feedback controls.
This knowledge identifies new ...
LAST 30 PRESS RELEASES:
Molecular hopscotch boosts light upconversion
Prolonged use of desogestrel pill linked to small increased brain tumour risk
Doctors raise concern over rise in recreational ketamine use
New index ranks 917 European cities on urban design for health and well-being
Exposure to pollution during pregnancy linked with changes in fetal brain structures
New way of measuring blood pressure could be a lifeline for thousands of people
Famous Ice Age ‘puppies’ likely wolf cubs and not dogs, study shows
Leg amputation caused by arterial disease four times higher in disadvantaged areas
Researchers solve ultrasound imaging problem using seismology technique
Among new dads, 64% take less than two weeks of leave after baby is born
Decades-old mystery of AlCl dipole moment resolved
Stroke, dementia more common in people with biomarker of aging
Shorter telomeres linked to increased risk of age-related brain diseases
Calling for renewed Israeli-Palestinian health cooperation
Rutgers health researchers challenge FDA warning on common epilepsy drug
In the belly of the beast: massive clumps reveal star factories from a bygone era of the cosmos
NASA’s Webb ‘UNCOVERs’ galaxy population driving cosmic renovation
Is your gut microbiome a calorie ‘super harvester’?
Some dog breeds are more likely to get diarrhea
Structural brain differences found in kids who experienced prenatal Superstorm Sandy exposure
Mapping patient satisfaction across U.S. hospitals reveals the Midwest as the leading region
Ladybirds' complex colors may result from a combination of pigments and physical properties of their wingcase
Exposure to multiple extreme climate events during pregnancy may have a cumulative effect on child brain development
Single-material electronic skin gives robots the human touch
What’s in a name? New research catalogues how birds are categorized by what we call them
Global mercury levels in rivers have doubled since Industrial Revolution
New ‘molecular GPS’ will fast-track drug discovery
Photonic processor could streamline 6G wireless signal processing
Scientists uncover insights into the origins of antibodies to peanut
Scientists map the first step in Alzheimer’s protein aggregation and discover clues for future therapies
[Press-News.org] Racial differences in clinical presentation in individuals diagnosed with frontotemporal dementiaJAMA Neurology