County-level sociodemographic characteristics and availability of COVID-19 therapeutic drugs

JAMA Network Open

2023-09-20

(Press-News.org) About The Study: The results of this study showed sociodemographic-based disparities in geographic clustering of COVID-19 therapeutic drugs, highlighting disparities in access to these drugs. With the end of the COVID-19 Public Health Emergency, these findings highlight an important gap in treatment access.

Authors: Kosuke Tamura, Ph.D., of the National Institutes of Health in Bethesda, Maryland, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2023.34763)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2023.34763?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=092023

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Consumption of ultraprocessed food and risk of depression

2023-09-20

About The Study: The findings of this study suggest that greater ultraprocessed food (UPF; i.e., energy-dense, palatable, and ready-to-eat items) intake, particularly artificial sweeteners and artificially sweetened beverages, is associated with increased risk of depression. Although the mechanism associating UPF to depression is unknown, recent experimental data suggests that artificial sweeteners elicit purinergic transmission in the brain, which may be involved in the etiopathogenesis of depression. Authors: Raaj S. Mehta, ...

Surrogate adiposity markers and mortality

2023-09-20

About The Study: Waist-to-hip ratio had the strongest and most consistent association with mortality irrespective of body mass index in this study consisting of 387,000 UK adult participants from the UK Biobank. Clinical recommendations should consider focusing on adiposity distribution compared with mass. Authors: Guillaume Pare, M.D., M.Sc., of the Vascular and Stroke Research Institute in Hamilton, Ontario, Canada, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2023.34836) Editor’s Note: Please see the article for additional ...

Strengthening artificial immune cells to fight cancer

2023-09-20

Among available immunotherapies, the use of «CAR-T» cells is proving extremely effective against certain blood cancers, but only in half of patients. A main reason for this is the premature dysfunction of these immune cells, which have been artificially modified in vitro. A team from the Universities of Geneva (UNIGE), Lausanne (UNIL), the Geneva University Hospitals (HUG) and the Vaud University Hospital (CHUV), all part of the Swiss Cancer Center Léman (SCCL), has discovered how to prolong the functionality of CAR-T cells. By inhibiting a very specific metabolic mechanism, the team has succeeded ...

Prehistoric fish fills 100 million year gap in evolution of the skull

2023-09-20

A 455-million-year-old fossil fish provides a new perspective on how vertebrates evolved to protect their brains, a study has found. In a paper published in Nature today (Wednesday 20th September), researchers from the University of Birmingham, Naturalis Biodiversity Centre in Leiden, Netherlands; and the Natural History Museum have pieced together the skull of Eriptychius americanus. The research, funded by the Leverhulme Trust, suggests that the ancient jawless fish found in ancient deposits in ...

Study finds firearm injuries increased in gentrified neighborhoods

2023-09-20

Brigham researchers reported that gentrified neighborhoods had a 62 percent higher firearm injury incidence rate than non-gentrified communities with comparable sociodemographic characteristics Understanding the reason for this increase is vital to reducing future firearm injuries Gentrification can have a ripple effect on communities. While it can improve certain conditions in typically low-income areas, rising housing costs can displace residents, causing social disruption and other downstream effects. Investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, conducted a study using national data to examine the relationship ...

Scientists reveal how the effects of psychosis spread throughout the brain

2023-09-20

Psychoses like schizophrenia cost billions of dollars annually and derail the lives of people struggling with the disease. Now Monash University researchers have modelled how the effects of psychosis spread through the brain, allowing them to isolate areas where these changes may originate from and which could be targeted by therapies designed to reduce the disease’s progression. The study, published today in the prestigious Journal of the American Medical Association Psychiatry, details how the scientists were able to map and model the spread of brain changes in people with different stages of psychoses such as schizophrenia,from people newly ...

Ya-Chieh Hsu, Ph.D. (Harvard) and Xuebing Wu, Ph.D. (Columbia) receive inaugural Glenn Foundation Discovery Awards

2023-09-20

Santa Barbara, CA and New York, NY -- The Glenn Foundation for Medical Research (GFMR) and the American Federation for Aging Research (AFAR) are pleased to announce the inaugural recipients of the 2023 Glenn Foundation Discovery Awards: Ya-Chieh Hsu, PhD, Professor of Stem Cell and Regenerative Biology at Harvard University, and a Principal Faculty Member at the Harvard Stem Cell Institute. Xuebing Wu, PhD, Assistant Professor of Medical Sciences (in Medicine and in Systems Biology), Columbia University. The Glenn Foundation Discovery Award was created to support research projects with strong potential to develop pioneering discoveries ...

Decoding depression: Researchers identify crucial biomarker that tracks recovery from treatment-resistant depression

2023-09-20

A team of leading clinicians, engineers, and neuroscientists has made a groundbreaking discovery in the field of treatment-resistant depression. By analyzing the brain activity of patients undergoing deep brain stimulation (DBS), a promising therapy involving implanted electrodes that stimulate the brain, the researchers identified a unique pattern in brain activity that reflects the recovery process in patients with treatment-resistant depression. This pattern, known as a biomarker, serves as a measurable indicator of disease recovery and represents a significant ...

CityU researchers develop novel photo-oxidation therapy for anticancer treatment

2023-09-20

A research team led by scientists from City University of Hong Kong (CityU) has achieved a significant breakthrough by inventing a new class of near-infrared-activated photo-oxidants that can effectively kill cancer cells without requiring oxygen. The photo-oxidants induce a unique form of cancer cell death that can overcome cancer cell resistance. The findings offer a new strategy, called ‘photo-oxidation therapy’, and provide a promising direction for the development of anti-cancer drugs. Photodynamic therapy, an innovative ...

Multimillion-dollar scientific grant program releases third cycle of funding to increase foundational understanding of sarcoidosis

2023-09-20

WASHINGTON (September 20, 2023)—The Ann Theodore Foundation Breakthrough Sarcoidosis Initiative (ATF-BSI), in partnership with the Milken Institute, launched its latest round of funding today. Up to $3.4 million in total funding will be made available to researchers from around the world whose work aims to increase scientific understanding of sarcoidosis. The program is accepting applications for two-year research projects and intends to award four to six research grants from doctorate-level investigators at qualifying research-based institutions worldwide. Awardees may be eligible for a third year of funding. Sarcoidosis is an inflammatory ...

County-level sociodemographic characteristics and availability of COVID-19 therapeutic drugs

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: