PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Federal peer review may be overstretched and error prone

Experts seek to improve peer review process

2011-01-11
(Press-News.org) The federal peer review system, by which research proposals are judged worthy for funding, may be "over stretched" and "susceptible to error," said Elmer Yglesias, a researcher at the Science and Technology Policy Institute and author of "Improving Peer Review in the Federal Government," published in the current issue of TECHNOLOGY & INNOVATION, Proceedings of the National Academy of Inventors ™, (www.academyofinventors.org) now available on-line at: http://www.cognizantcommunication.com/filecabinet/Technology/techinnovation.html

According to Yglesias, the federal peer review system is awash in an increasing number of funding proposals, leaving him to wonder if the peer review system is up to the challenge.

"Indications are that the system is over stretched," said Yglesias. "In addition, the number of U.S. researchers qualified to perform these reviews is not only limited, but declining as well. With fewer reviewers, funding decisions are more susceptible to error."

Not unlike a systematic check might be instituted for an engineering quality issue, Yglesias recommends a system of "calibration" to mitigate undesired outcomes. Calibration, he suggested, might prevent three kinds of errors: errors occurring because a proposal is selected for funding when it should not have been because of the reviewers failing to get good instructions and, second, errors occurring because reviewers were biased and swayed the panel. A third kind of error comes from over confident reviewers.

"This error occurs because some reviewers are correct far less than they think," commented Yglesias.

For Yglesias, the peer review system can be improved and validated through "calibration," which he defines as the use of specific measurement techniques compared to a standard. Providing standard examples to reviewers and running mock reviews would help, he added.

"Unfortunately, not many program officers are trained to facilitate a calibration," said Yglesias. "Also, it requires extra time and resources."

For a calibration program, he recommends "Calibrated Peer Review" ™, a web-based program developed at UCLA through which student writing assignments are graded by student peers.

"It would not be difficult to conceive a similar system to calibrate the review of scientific proposals," he concluded.

### The National Academy of Inventors ™ recognizes and encourages inventors who have a patent issued from the U.S. Patent and Trademark Office, enhances the visibility of university technology and academic innovation, encourages the disclosure of intellectual property, educates and mentors innovative students, and encourages the translation of the inventions of its members to benefit society.

The editorial offices of TECHNOLOGY and INNOVATION are located at the University of South Florida, Office of Research and Innovation, 3702 Spectrum Blvd., Suite 175, Tampa, Florida, 33612. Tel: (813) 974-3181. Email jlowry@research.usf.edu

News Release by Randolph Fillmore, Florida Science Communications, www.sciencescribe.net



ELSE PRESS RELEASES FROM THIS DATE:

Radiometer finds sources of fire

Radiometer finds sources of fire
2011-01-11
The number and scale of forest fires has increased dramatically in recent decades. Who can forget last summer's television images of blazing infernos devouring miles and miles of forest in Russia, Australia and California? In Germany, too, several regions are under threat precipitated by climate change – Brandenburg, for example, is one of the areas of Europe that are most at risk. Often, fires can only be contained from the air. In order to fight them in a targeted way, firefighting planes need to be given precise information on where the flames are at their worst. Infrared ...

No left turn: 'Superstreet' traffic design improves travel time, safety

No left turn: Superstreet traffic design improves travel time, safety
2011-01-11
The so-called "superstreet" traffic design results in significantly faster travel times, and leads to a drastic reduction in automobile collisions and injuries, according to North Carolina State University researchers who have conducted the largest-ever study of superstreets and their impacts. Superstreets are surface roads, not freeways. It is defined as a thoroughfare where the left-hand turns from side streets are re-routed, as is traffic from side streets that needs to cross the thoroughfare. In both instances, drivers are first required to make a right turn and ...

Researchers create 'scoring system' for PTEN mutation testing

2011-01-11
Monday, January 10, 2011 – Cleveland – Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers. The research has created a diagnostic scoring system that improves on established criteria. Led by Charis Eng, M.D., Ph.D., Chair of the Genomic Medicine Institute at the Lerner Research Institute of Cleveland Clinic, the study – the largest clinical study to date on the identification ...

Minerals provide better indoor air

Minerals provide better indoor air
2011-01-11
Since the 50s, formaldehyde has been the basic material for many artificial resins and glues used in particleboards and plywood boards. Estimates indicate that more than 85 percent of all wood materials have adhesives containing formaldehyde. This substance escapes from the materials and, along with other sources, pollutes indoor air. This is why numerous ways have been developed to reduce emissions, and the International Agency for Research on Cancer (IARC) of the World Health Organization WHO has even classified formaldehyde as carcinogenic for humans. Thereupon both ...

Social class and changes in mortality from liver cirrhosis over the 20th Century

2011-01-11
A paper describing a dramatic change during the 20th century in England and Wales in the association between social class and mortality from liver cirrhosis features in Alcohol and Alcoholism. While deaths from cirrhosis were more common among higher social classes in the early part of the century, the pattern changed so that deaths from cirrhosis were much more common among the lower social classes by the end of the century. Data on male cirrhosis mortality by social class were obtained from the Registrar General's Decennial Supplements for the years 1921�. The ...

Researchers show how Alzheimer's plaques lead to loss of nitric oxide in brain

2011-01-11
PITTSBURGH, Jan. 10 – A researcher at the University of Pittsburgh School of Medicine, in collaboration with scientists from the National Institutes of Health (NIH), has discovered that the deadly plaques of Alzheimer's disease interact with certain cellular proteins to inhibit normal signals that maintain blood flow to the brain. Their findings, which could lead to new approaches to treat the dementia, were recently published in Public Library of Science One. Levels of nitric oxide (NO) – a signaling molecule that helps regulate blood flow, immune and neurological processes ...

Species loss tied to ecosystem collapse and recovery

Species loss tied to ecosystem collapse and recovery
2011-01-11
PROVIDENCE, R.I. [Brown University] — The world's oceans are under siege. Conservation biologists regularly note the precipitous decline of key species, such as cod, bluefin tuna, swordfish and sharks. Lose enough of these top-line predators (among other species), and the fear is that the oceanic web of life may collapse. In a new paper in Geology, researchers at Brown University and the University of Washington used a group of marine creatures similar to today's nautilus to examine the collapse of marine ecosystems that coincided with two of the greatest mass extinctions ...

Early investigations promising for detecting metastatic breast cancer cells

Early investigations promising for detecting metastatic breast cancer cells
2011-01-11
Research by engineers and cancer biologists at Virginia Tech indicate that using specific silicon microdevices might provide a new way to screen breast cancer cells' ability to metastasize. An image of their work provided to Biomaterials was selected as one of the 12 best biomaterials-related images published in the journal's 2010 catalogue. http://www.elsevierscitech.com/pdfs/Biomaterials_2010.pdf The Virginia Tech researchers are: Masoud Agah, director of Virginia Tech's Microelectromechanical Systems Laboratory (MEMS) Laboratory in the Bradley Department of Electrical ...

Research identifies drug target for prion diseases, 'mad cow'

2011-01-11
LEXINGTON, Ky. (Jan. 4, 2011) − Scientists at the University of Kentucky have discovered that plasminogen, a protein used by the body to break up blood clots, speeds up the progress of prion diseases such as mad cow disease. This finding makes plasminogen a promising new target for the development of drugs to treat prion diseases in humans and animals, says study senior author Chongsuk Ryou, a researcher at the UK Sanders-Brown Center on Aging and professor of microbiology, immunology and molecular genetics in the UK College of Medicine. "I hope that our study ...

Earth: Finding new oil and gas frontiers

2011-01-11
Alexandria, VA – Where to next in the search for oil and gas? EARTH examines several possible new frontiers - including the Arctic, the Falkland Islands, the Levant, Trinidad and Tobago and Sudan - where oil and gas exploration are starting to take hold. One of those places, Sudan, is in the news for other reasons: South Sudan voted yesterday on whether to secede from North Sudan. But given that South Sudan holds more than 70 percent of Sudan's 5 billion to 6 billion barrels of proven reserves, a lot in this election hinges on oil. If South Sudan does secede, how will ...

LAST 30 PRESS RELEASES:

Medigap protection and plan switching among Medicare advantage enrollees with cancer

Bubbles are key to new surface coating method for lightweight magnesium alloys

Carbon stable isotope values yield different dietary associations with added sugars in children compared to adults

Scientists discover 230 new giant viruses that shape ocean life and health

Hurricanes create powerful changes deep in the ocean, study reveals

Genetic link found between iron deficiency and Crohn’s disease

Biologists target lifecycle of deadly parasite

nTIDE June 2025 Jobs Report: Employment of people with disabilities holds steady in the face of uncertainty

Throughput computing enables astronomers to use AI to decode iconic black holes

Why some kids respond better to myopia lenses? Genes might hold the answer

Kelp forest collapse alters food web and energy dynamics in the Gulf of Maine

Improving T cell responses to vaccines

Nurses speak out: fixing care for disadvantaged patients

Fecal transplants: Promising treatment or potential health risk?

US workers’ self-reported mental health outcomes by industry and occupation

Support for care economy policies by political affiliation and caregiving responsibilities

Mailed self-collection HPV tests boost cervical cancer screening rates

AMS announces 1,000 broadcast meteorologists certified

Many Americans unaware high blood pressure usually has no noticeable symptoms

IEEE study describes polymer waveguides for reliable, high-capacity optical communication

Motor protein myosin XI is crucial for active boron uptake in plants

Ultra-selective aptamers give viruses a taste of their own medicine

How the brain distinguishes between ambiguous hypotheses

New AI reimagines infectious disease forecasting

Scientific community urges greater action against the silent rise of liver diseases

Tiny but mighty: sophisticated next-gen transistors hold great promise

World's first practical surface-emitting laser for optical fiber communications developed: advancing miniaturization, energy efficiency, and cost reduction of light sources

Statins may reduce risk of death by 39% for patients with life-threatening sepsis

Paradigm shift: Chinese scientists transform "dispensable" spleen into universal regenerative hub

Medieval murder: Records suggest vengeful noblewoman had priest assassinated in 688-year-old cold case

[Press-News.org] Federal peer review may be overstretched and error prone
Experts seek to improve peer review process