Almost 1:10 adolescents non-prescription weight loss products globally

One of the important breakthroughs that made it possible to program or reprogram cell fate more efficiently and with higher fidelity in a dish was discovering how to make use of a small set of molecular cowboys called pioneer transcription factors (TFs). Every cell in our bodies has more than 200 transcription factors expressed inside, riding along the DNA helix instructing specific genes to activate and deactivate. During the early stages of fetal development, a small subset of “pioneer” TFs act inside ...

Researchers led by Prof. HUANG Qing from the Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences, in collaboration with researchers from the Zhejiang Institute of Tianjin University, and Linköping University, Sweden, has proposed a general A-site alloying strategy for the preparation of noble metal-occupied MAX phases. This work was published in Matter. MAX phases are a family of ternary layered transition metal carbides that have attracted great attention ...

A paper describing the architectures, opportunities, and challenges of the IoB was published in the journal Green Energy and Intelligent Transportation on September 7th, 2023.   The present battery technology employed in electric vehicles (EVs) faces several critical challenges. Firstly, the limited operation range of EVs remains a major concern for potential users, as it affects their ability to travel long distances without the need for frequent recharging. Additionally, long charging times are inconvenient ...

The boundary between everyday reality and the quantum world remains unclear. The more massive an object, the more localized it becomes when being made quantum through cooling down its motion to the absolute zero. Researchers, led by Oriol Romero-Isart from the Institute for Quantum Optics and Quantum Information (IQOQI) of the Austrian Academy of Sciences (ÖAW) and the Department of Theoretical Physics at the University of Innsbruck, propose an experiment in which an optically levitated nanoparticle, cooled to its ground state, evolves in a non-optical (“dark”) potential created by electrostatic or magnetic forces. This evolution in the dark potential ...

Columbia engineers have built a new AI that shatters a long-held belief in forensics–that fingerprints from different fingers of the same person are unique. It turns out they are similar, only we’ve been comparing fingerprints the wrong way! New York, NY—January 12, 2024—From “Law and Order” to “CSI,” not to mention real life, investigators have used fingerprints as the gold standard for linking criminals to a crime. But if a perpetrator leaves prints from different fingers in two different crime scenes, these scenes are very difficult to link, and the trace can go ...

JMIR Publications is pleased to announce that JMIR Mental Health (JMH) has been accepted for inclusion in MEDLINE, which is the U.S. National Library of Medicine's premier bibliographic database. JMIR Mental Health had already been indexed in PubMed previously. MEDLINE is a more selective subset of PubMed, consisting of the top 5,200 biomedical journals. Indexing in MEDLINE also means that articles are now also indexed with NLM Medical Subject Headings (MeSH terms) and other metadata. Selection for MEDLINE is a result of a thorough review of the ...

Reducing stimulant use was associated with significant improvement in measures of health and recovery among people with stimulant use disorder, even if they did not achieve total abstinence. This finding is according to an analysis of data from 13 randomized clinical trials of treatments for stimulant use disorders involving methamphetamine and cocaine. Historically, total abstinence has been the standard goal of treatment for substance use disorders, however, these findings support the growing recognition that a more nuanced perspective on measuring treatment success may be beneficial. The study, published in Addiction, was led by scientists at the Johns Hopkins Bloomberg School of Public ...

Boston – Like a criminal entering a witness protection program, cancer cells can shed their past and take on a new identity. Detecting such an identity-switch is particularly challenging when metastatic castration-resistant prostate cancer (CRPC) advances from adenocarcinoma to neuroendocrine prostate cancer (NEPC), a very difficult cancer to treat. Now, however, researchers at Dana-Farber Cancer Institute and the University of Trento, Italy, have developed a blood test, described in Cancer Discovery, that can ...

Cigarette smoking remains the leading avoidable cause of premature death in the United States, accounting for approximately 500,000 deaths or 1 in 5 deaths annually. According to the U.S. Department of Health and Human Services, most adults who smoke cigarettes started before age 18, so preventing cigarette smoking in adolescents is important to reducing smoking in adults.  In a new study, researchers from Florida Atlantic University’s Schmidt College of Medicine and collaborators explored overall trends in cigarette smoking among a large sample of U.S. adolescents in grades nine to 12 from 1991 to 2021. They ...

Many edible, medicinal, and poisonous mushrooms that we are familiar with belong to the order Agaricales, which is a group of fungi with important economic and ecological value. Understanding the phylogenetic relationships of Agaricales can help us to know their evolutionary history and diversity, as well as their interactions with other organisms. Moreover, the phylogenetic framework of Agaricales can provide a basis for conserving biodiversity, such as measuring phylogenetic diversity and assessing the uniqueness and importance of different species.   Previous studies divided Agaricales into 8 suborders and 46 families, but the systematic position and phylogenetic relationship ...