(Press-News.org) Physicians who are notified that a patient has died of a drug overdose are more judicious in issuing controlled substances if the notification includes a plan for what to do during subsequent patient visits, according to a study published today in Nature Communications.
Compared to a letter with demonstrated effectiveness at improving prescribing safety, physicians who received notifications with additional planning guidance reduced prescriptions of opioids by nearly 13%. They also reduced prescriptions of the anxiety medications benzodiazepines and by more than 8%. Together these drugs constitute the bulk of prescription drug overdoses.
The results suggest that the guidance, known as if/when planning prompts, may lower risks to patients by reducing the intensity and frequency of these prescriptions. The findings also indicate that letters notifying a physician that a patient has fatally overdosed are more effective when they include the guidance prompts.
The letter with planning prompts asked the doctor to carry out a specific plan: “When your next patient presents with pain, keep… [these] ... recommendations close at hand to assist with their safe care. Also, be comfortable voicing your concern about prescribing safety with them so that they are also aware of the dangers associated with scheduled drugs.”
“Providing physicians a simple plan that will guide them at a patient visit appears to help temper their use of these drugs,” said Jason Doctor, lead author of the study and co-director of the Behavioral Sciences Program at the USC Schaeffer Center for Health Policy and Economics. “This represents a promising approach to reducing fatal drug overdoses, one that is both affordable and scalable.”
The study builds on two previous ones conducted by Doctor and his colleagues. The first one found that physicians reduced opioid prescriptions by 10% in the three months following notification of a fatal overdose. A second study found that physicians reduced opioid prescriptions by 7% one year after receiving notification. The letter used in these previous studies served as the control in this study.
“This latest study is part of an evolution toward better understanding how to enact behavior change among physicians whose patients have suffered negative consequences from care by the medical community,” said Doctor, who is also chair of the Department of Health Policy and Management at the USC Sol Price School of Public Policy.
The latest randomized study involved sending letters to 541 clinicians in Los Angeles County: 284 received a standard letter notifying them that a patient had died of an overdose; 257 received a letter with the additional guidance.
About the Study
In addition to Doctor, the study’s authors included Emily Stewart, staff at the USC Price School; Marcella A. Kelley of Edwards Lifesciences; Noah J. Goldstein of the UCLA Anderson School of Management and UCLA Geffen School of Medicine; and Jonathan Lucas of the Los Angeles County’s Department of Medical Examiner-Coroner.
The study was supported by the National Institutes on Aging (P30AG024968).
###
END
Want safer prescribing? Provide doctors with a plan for helping patients in pain
Letters notifying physicians of patient overdose deaths and providing a plan for the future is an effective intervention, according to new study
2024-01-12
ELSE PRESS RELEASES FROM THIS DATE:
Study uncovers potential origins of life in ancient hot springs
2024-01-12
Newcastle University research turns to ancient hot springs to explore the origins of life on Earth.
The research team, funded by the UK’s Natural Environmental Research Council, investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists at Newcastle University found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including ...
Nutritional acquired immunodeficiency (N-AIDS) is the leading driver of the TB pandemic
2024-01-12
(Boston)—Tuberculosis (TB) is the leading infectious killer worldwide, with 10.6 million cases and 1.6 million deaths in 2021 alone. One in five incident TB cases were attributable to malnutrition, more than double the number attributed to HIV/AIDS. Like HIV/AIDS, malnutrition is a cause of secondary immunodeficiency, known as nutritionally acquired immunodeficiency syndrome (N-AIDS). However, N-AIDS remains the neglected cousin of HIV/AIDS in global TB elimination efforts.
In a review paper led by Madolyn Dauphinais, MPH, researchers at Boston University Chobanian ...
Obesity linked to detection of blood cancer precursor
2024-01-12
(WASHINGTON, January 12, 2024) – Individuals with obesity are more likely to have monoclonal gammopathy of undetermined significance (MGUS), a benign blood condition that often precedes multiple myeloma, according to new research published in Blood Advances.
Multiple myeloma is a blood cancer of the plasma cells, a type of white blood cells that produce antibodies to fight infection. MGUS, characterized by an abnormal protein produced by plasma cells, is a known precursor to multiple myeloma. Most people with MGUS exhibit no significant symptoms and are not immediately ill. Rather, the presence of MGUS serves as a warning to monitor for the potential ...
How gum disease aggravates chronic obstructive pulmonary disease
2024-01-12
Highlights:
Previous studies have connected severe gum disease to chronic obstructive pulmonary disease, or COPD.
Bacteria play a critical role, but the details remain unclear.
A new study shows how periodontitis, an oral disease, activates immune cells associated with aggravated progression of COPD.
The findings suggest that periodontitis and COPD together worsen COPD, and point to gum disease management as a potential treatment for COPD.
Washington, D.C.—Severe gum disease has been linked to the progression of chronic obstructive pulmonary disease, or COPD, but an understanding ...
ASM expands clinically relevant research with launch of ASM Case Reports
2024-01-12
Washington, D.C.—The American Society for Microbiology (ASM) announces the launch of its new fully open access journal, ASM Case Reports, which will begin publishing case reports in 2025 and accepting submissions starting mid-2024. ASM Case Reports will be a dedicated platform for the prompt publication of high-quality case reports in clinical microbiology and infectious diseases, an extensive and rapidly growing body of research.
ASM Case Reports will explore new diseases, elaborate disease progressions, the detailed actions and effects of pharmaceuticals, ...
Rice researchers revolutionizing 5G network testing
2024-01-12
With the potential to transform the future of global wireless networks, Rice University engineers are developing a cutting-edge testing framework to assess the stability, interoperability, energy efficiency and communication performance of software-based machine learning-enabled 5G radio access networks (RANs).
As 5G networks evolve toward more software-centric architectures, there is a critical need for advanced testing methods to ensure robust real-time performance. Funded by a $1.9 million grant from the U.S. Department of Commerce’s National Telecommunications and Information ...
Candida evolution disclosed: new insights into fungal infections
2024-01-12
Barcelona, 12 January 2024 – Global fungal infections, which affect one billion people and cause 1.5 million deaths each year, are on the rise due to the increasing number of medical treatments that heighten vulnerability. Patients undergoing chemotherapy or immunosuppressive treatments after organ transplant often present compromised immune systems. Given the emergence of resistant strains, the limited variety of current antifungal drugs as well as their cost and side effects, the treatment of these infections is challenging and brings about an urgent need for more effective treatments.
In this context, a team from the Institute for ...
Study reveals function of little-understood synapse in the brain
2024-01-12
New research from Oregon Health & Science University for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer’s disease, to a type of brain cancer known as glioma.
The study published today in the journal Nature Neuroscience.
Neuroscientists focused on the junction, or synapse, connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells, or OPCs. OPCs can differentiate into oligodendrocytes, which produce a sheath around nerves known as myelin. Myelin is ...
Spying on a shape-shifting protein
2024-01-12
NEW YORK, January 12, 2024 — Proteins do the heavy lifting of performing biochemical functions in our bodies by binding to metabolites or other proteins to complete tasks. To do this successfully, protein molecules often shape-shift to allow specific binding interactions that are needed to perform complex, precise chemical processes.
A better understanding of the shapes proteins take on would give researchers important insight into stopping or treating diseases, but current methods for revealing these dynamic, three-dimensional forms offer scientists limited information. To address this knowledge ...
Researchers sequence the first genome of myxini, the only vertebrate lineage that had no reference genome
2024-01-12
An international scientific team made up of more than 40 authors from seven different countries, led by the researcher at the University of Malaga Juan Pascual Anaya, has managed to sequence the first genome of the myxini –also known as ‘hagfish’–, the only large group of vertebrates for which there was no reference genome of any of its species yet.
This finding, published in the scientific journal ‘Nature Ecology & Evolution’, has allowed deciphering the evolutionary history of genome duplications –number of times a ...
LAST 30 PRESS RELEASES:
Duke-NUS scientists identify more effective way to detect poultry viruses in live markets
Low-intensity treadmill exercise preconditioning mitigates post-stroke injury in mouse models
How moss helped solve a grave-robbing mystery
How much sleep do teens get? Six-seven hours.
Patients regain weight rapidly after stopping weight loss drugs – but still keep off a quarter of weight lost
GLP-1 diabetes drugs linked to reduced risk of addiction and substance-related death
Councils face industry legal threats for campaigns warning against wood burning stoves
GLP-1 medications get at the heart of addiction: study
Global trauma study highlights shared learning as interest in whole blood resurges
Almost a third of Gen Z men agree a wife should obey her husband
Trapping light on thermal photodetectors shatters speed records
New review highlights the future of tubular solid oxide fuel cells for clean energy systems
Pig farm ammonia pollution may indirectly accelerate climate warming, new study finds
Modified biochar helps compost retain nitrogen and build richer soil organic matter
First gene regulation clinical trials for epilepsy show promising results
Life-changing drug identified for children with rare epilepsy
Husker researchers collaborate to explore fear of spiders
Mayo Clinic researchers discover hidden brain map that may improve epilepsy care
NYCST announces Round 2 Awards for space technology projects
How the Dobbs decision and abortion restrictions changed where medical students apply to residency programs
Microwave frying can help lower oil content for healthier French fries
In MS, wearable sensors may help identify people at risk of worsening disability
Study: Football associated with nearly one in five brain injuries in youth sports
Machine-learning immune-system analysis study may hold clues to personalized medicine
A promising potential therapeutic strategy for Rett syndrome
How time changes impact public sentiment in the U.S.
Analysis of charred food in pot reveals that prehistoric Europeans had surprisingly complex cuisines
As a whole, LGB+ workers in the NHS do not experience pay gaps compared to their heterosexual colleagues
How cocaine rewires the brain to drive relapse
Mosquito monitoring through sound - implications for AI species recognition
[Press-News.org] Want safer prescribing? Provide doctors with a plan for helping patients in painLetters notifying physicians of patient overdose deaths and providing a plan for the future is an effective intervention, according to new study


