PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

MD Anderson researchers receive over $25.5 million in CPRIT funding

2024-02-21
(Press-News.org) HOUSTON ― The University of Texas MD Anderson Cancer Center today was awarded 16 grants totaling over $25.5 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of cancer screening, early detection and prevention programs, faculty recruitment, and groundbreaking cancer research across all areas of the institution.

“We are grateful for CPRIT’s continued funding of impactful cancer research and prevention programs at MD Anderson, which propels our efforts to deliver new breakthroughs and to advance our mission to end cancer,” said Peter WT Pisters, M.D., president of MD Anderson. “These efforts are pivotal to our institutional strategy and are grounded in our unwavering commitment to transform the lives of patients in Texas, across the nation and around the world.”

Since its inception, CPRIT has awarded more than $3.4 billion in grants for cancer research. MD Anderson investigators have received $620 million altogether, approximately 18% of the total awards. Programs supported by CPRIT funding have brought more than 302 distinguished cancer researchers to Texas, advanced the knowledge base for cancer treatment throughout the state and provided more than 9 million cancer prevention and early detection services reaching all 254 counties in Texas.

CPRIT awards to MD Anderson include:

Prevention Awards:

Expanding Access to Cervical Cancer Screening through Primary HR-HPV Testing and Self-Sampling: A Multicomponent Intervention for Safety Net Health Systems (Jane Montealegre, Ph.D., Behavioral Science) - $2,499,646 Preventing Tobacco Related Cancers by Expanding Capacity for Tobacco Use Interventions Within Agencies Serving Women with Behavioral Health Needs (Lorraine Reitzel, Ph.D., Health Disparities Research) - $2,487,822 Integrated Mammography and Genetic Evaluation Services (Gary Whitman, M.D., Breast Imaging) - $1,499,400 Individual Investigator Awards:

Dissection of CAMKK2’s Tumor Cell-Intrinsic and -Extrinsic Roles in Prostate Cancer (Daniel Frigo, Ph.D., Cancer Systems Imaging) - $1,050,000 Identify Radiopathomics Markers to Guide Immunotherapy for Non-Small Cell Lung Cancer (Jia Wu, Ph.D., Imaging Physics) - $1,049,906 Immune-Related Determinants of HPV-Associated Oropharyngeal Cancer Outcomes (Guojun Li, M.D., Ph.D., Head and Neck Surgery) - $1,049,726 Immunoprevention of Breast Cancer Brain Metastasis by Special Dendritic Cell-Derived Extracellular Vesicles (Dihua Yu, M.D., Ph.D., Molecular and Cellular Oncology) - $1,050,000 Targeting Cancer-Associated Lactobacillus Iners to Improve Response to Cancer Therapy (Lauren Colbert, M.D., Radiation Oncology) - $1,049,427 The Epigenetic Impact and Therapeutic Opportunity of AR-Directed Therapy for DSRCT (Joseph Ludwig, M.D., Sarcoma Medical Oncology) - $1,398,788 Investigating the Impact of Interferon Gamma Signaling on Therapeutic Resistance in Acute Myeloid Leukemia (Hussein Abbas, M.D., Ph.D., Leukemia) - $1,042,256 Epigenetic Mechanism and Targeting During Response to BRAFi/Anti-EGFR Therapy in BRAF-Mutant Colorectal Cancers (Scott Kopetz, M.D., Ph.D., Gastrointestinal Medical Oncology) - $1,043,909 Therapeutic Vulnerabilities and Predictors of Response to Chemo(immuno)therapy in Patients with High-Risk, Early-Stage Triple-Negative Breast Cancer (TNBC) (Anil Korkut, Ph.D., Bioinformatics and Computational Biology) - $1,199,999 Treatment Planning of ADC Therapy for Ovarian Cancer with Molecular Photoacoustic-Ultrasonic Imaging (Richard Bouchard, Ph.D., Imaging Physics) - $1,049,859 Translation of Gut Commensal Bacteria Peptidoglycan Remodeling Pathway for Chimeric Antigen Receptor T-Cell Therapy (Neeraj Saini, M.D., Stem Cell Transplantation and Cellular Therapy) - $1,050,000 Identifying Tumor Specific Vulnerabilities in Appendiceal Adenocarcinoma: A Systems Approach (John Paul Shen, M.D., Gastrointestinal Medical Oncology) - $1,050,000 Scholar Recruitment Awards:

Recruitment of Established Investigator Award - $6,000,000 Read this press release in the MD Anderson Newsroom.

- 30 -

END



ELSE PRESS RELEASES FROM THIS DATE:

Hippo signaling pathway gives new insight into systemic sclerosis

2024-02-21
Systemic sclerosis causes the skin to tighten and harden resulting in a potentially fatal autoimmune condition that is associated with lung fibrosis and kidney disease.  University of Michigan Health researchers have studied the pathology of systemic sclerosis to understand better the disease and identify key pathways in the disease process that can be targeted therapeutically. A research team led by University of Michigan Health’s Dinesh Khanna, M.B.B.S., M.Sc.,  professor of rheumatology and Johann Gudjonsson, M.D., Ph.D., professor of dermatology, ...

Utah’s Bonneville Salt Flats has long been in flux

Utah’s Bonneville Salt Flats has long been in flux
2024-02-21
It has been long assumed that Utah’s Bonneville Salt Flats was formed as its ancient namesake lake dried up 13,000 years ago. But new research from the University of Utah has gutted that narrative, determining these crusts did not form until several thousand years after Lake Bonneville disappeared, which could have important implications for managing this feature that has been shrinking for decades to the dismay of the racing community and others who revere the saline pan 100 miles west of Salt ...

UM School of Medicine receives $10.6 million in state funding for Abortion Clinical Care Training Program

2024-02-21
A $10.6 million training grant has been awarded to the University of Maryland School of Medicine (UMSOM) and University of Maryland, Baltimore (UMB) to administer Maryland’s Abortion Clinical Care Training Program. The grant will be used to expand the number of healthcare professionals with abortion care training, increase the racial and ethnic diversity among health care professionals with abortion care education, and support the identification of clinical sites needing training. “Our training will target a major ...

Outsmarting chemo-resistant ovarian cancer

2024-02-21
  · Most women with ovarian cancer develop resistance to chemotherapy · Nanoparticle fools cancer cells and prevents cholesterol from entering · More than 18,000 women a year die from ovarian cancer CHICAGO --- Women diagnosed with ovarian cancer may initially respond well to chemotherapy, but the majority of them will develop resistance to treatment and die from the disease.  Now Northwestern Medicine scientists have discovered the Achilles heel of chemotherapy-resistant ovarian cancer — its hunger for cholesterol — and how to sneakily use that to destroy it. In a new study, scientists first showed that chemotherapy-resistant ...

Does Russia stand to benefit from climate change?

Does Russia stand to benefit from climate change?
2024-02-21
“There’s a narrative out there about climate change that says there are winners and losers. Even if most of the planet might lose from the changing climate, certain industries and countries stand to benefit. And Russia is usually at the tip of people’s tongues, with Russian officials even making the claim that Russia is a potential winner.” This portrayal, described by Debra Javeline, associate professor of political science at the University of Notre Dame and lead author on the recently published study “Russia in a changing climate,” was debated ...

Researchers find possible solutions to reverse Alzheimer’s Disease impact

2024-02-21
University of North Carolina at Chapel Hill researchers have developed a new drug delivery platform that harnesses helical amyloid fibers designed to untwist and release drugs in response to body temperatures. A new research paper published on Jan. 26 in Nature Communications reveals groundbreaking structural details into how diseases form much like Alzheimer’s disease. With this knowledge, the group may have uncovered a unique mechanism to reverse both the deposits and their impact on those suffering from these conditions. UNC-Chapel Hill researcher Ronit Freeman ...

A Mount Sinai-led study shows early success of a novel drug in treating a rare and chronic blood cancer

2024-02-21
New York, NY (February 21, 2024) – A novel treatment for polycythemia vera, a potentially fatal blood cancer, demonstrated the ability to control overproduction of red blood cells, the hallmark of this malignancy and many of its debilitating symptoms in a multi-center clinical trial led by the Icahn School of Medicine at Mount Sinai.   In the phase 2 study, the drug rusfertide limited excess production of red blood cells, the main manifestation of polycythemia vera, over the 28-week course of ...

Muscle as a heart-health predictor

Muscle as a heart-health predictor
2024-02-21
Body composition — often expressed as the amount of fat in relation to muscle — is one of the standard predictors of cardiac health. Now, new research from the University of California San Diego indicates more muscle doesn’t automatically mean lower risk of heart trouble. The study, published in the Journal of the American Heart Association, found all muscle isn’t the same. Britta Larsen, PhD, says men with a higher area of abdominal muscle have a greater risk of cardiac trouble. It’s a completely different ...

Air pollution linked to more signs of Alzheimer’s in brain

2024-02-21
EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, FEBRUARY 21, 2024 MINNEAPOLIS – People with higher exposure to traffic-related air pollution were more likely to have high amounts of amyloid plaques in their brains associated with Alzheimer’s disease after death, according to a study published in the February 21, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers looked at fine particulate matter, PM2.5, which consists of pollutant particles of less than 2.5 microns in diameter suspended in air. The study does not prove that air pollution causes more amyloid plaques in the brain. It only ...

More than 40% of Americans know someone who died of drug overdose

2024-02-21
More than 40% of Americans know someone who has died of a drug overdose and about one-third of those individuals say their lives were disrupted by the death, according to a new RAND study.   Analyzing a national representative survey of American adults, researchers found that the lifetime exposure to an overdose death is more common among women than men, married participants than unmarried participants, U.S.-born participants than immigrants, and those who live in urban settings as compared to those in rural settings.   Rates of exposure were significantly higher in New England (Connecticut, Maine, Massachusetts, ...

LAST 30 PRESS RELEASES:

Preschool education: A key to supporting allophone children

CNIC scientists discover a key mechanism in fat cells that protects the body against energetic excess

Chemical replacement of TNT explosive more harmful to plants, study shows

Scientists reveal possible role of iron sulfides in creating life in terrestrial hot springs

Hormone therapy affects the metabolic health of transgender individuals

Survey of 12 European countries reveals the best and worst for smoke-free homes

First new treatment for asthma attacks in 50 years

Certain HRT tablets linked to increased heart disease and blood clot risk

Talking therapy and rehabilitation probably improve long covid symptoms, but effects modest

Ban medical research with links to the fossil fuel industry, say experts

Different menopausal hormone treatments pose different risks

Novel CAR T cell therapy obe-cel demonstrates high response rates in adult patients with advanced B-cell ALL

Clinical trial at Emory University reveals twice-yearly injection to be 96% effective in HIV prevention

Discovering the traits of extinct birds

Are health care disparities tied to worse outcomes for kids with MS?

For those with CTE, family history of mental illness tied to aggression in middle age

The sound of traffic increases stress and anxiety

Global food yields have grown steadily during last six decades

Children who grow up with pets or on farms may develop allergies at lower rates because their gut microbiome develops with more anaerobic commensals, per fecal analysis in small cohort study

North American Early Paleoindians almost 13,000 years ago used the bones of canids, felids, and hares to create needles in modern-day Wyoming, potentially to make the tailored fur garments which enabl

Higher levels of democracy and lower levels of corruption are associated with more doctors, independent of healthcare spending, per cross-sectional study of 134 countries

In major materials breakthrough, UVA team solves a nearly 200-year-old challenge in polymers

Wyoming research shows early North Americans made needles from fur-bearers

Preclinical tests show mRNA-based treatments effective for blinding condition

Velcro DNA helps build nanorobotic Meccano

Oceans emit sulfur and cool the climate more than previously thought

Nanorobot hand made of DNA grabs viruses for diagnostics and blocks cell entry

Rare, mysterious brain malformations in children linked to protein misfolding, study finds

Newly designed nanomaterial shows promise as antimicrobial agent

Scientists glue two proteins together, driving cancer cells to self-destruct

[Press-News.org] MD Anderson researchers receive over $25.5 million in CPRIT funding