(Press-News.org) "Trans masculine people are people born female but do not identify as such, for example they feel male, gender fluid or non-binary. Our examination of their ovarian tissue shows that 33% of them show signs of recent ovulation, despite being on testosterone and no longer menstruating," says Joyce Asseler, PhD candidate at Amsterdam UMC.
Trans masculine people often use hormone treatment with testosterone to masculinize physically. This hormone usually stops them from menstruating. In that case, it is often assumed that ovulation does not take place.
Physician-researcher Joyce Asseler and gynecologist Norah van Mello examined the ovarian tissue of transgender people who had their ovaries removed as part of their gender-affirming treatment. They had all used testosterone for at least 1 year prior to and at the time of the procedure. Their analysis shows that 17 of the 52 study participants (33%) show signs of recent ovulation in the ovarian tissue.
"Testosterone apparently has a heterogenous effect on ovarian tissue. We don't know why one person ovulates and another person doesn't. In any case, we cannot explain this difference by the type of testosterone, or how long someone has been taking testosterone," says Asseler.
People who ovulate can, in theory, also get pregnant. This also applies to these trans people. For them, it is therefore necessary to use contraceptives if they are sexually active with someone who produces sperm cells. "The physical and mental consequences of an unplanned and unwanted pregnancy are enormous. It is important that trans masculine people and their healthcare providers are aware of this risk and act accordingly. Furthermore, this discovery can contribute to better care for trans masculine people who experience abdominal cramping," concludes Asseler.
END
A third of trans masculine individuals on testosterone ovulate
Study from Amsterdam UMC's Center of Expertise on Gender Dysphoria shows that one-third of trans masculine individuals taking testosterone ovulate
2024-02-22
ELSE PRESS RELEASES FROM THIS DATE:
Researchers use deep brain stimulation to map therapeutic targets for four brain disorders
2024-02-22
A new study led by investigators from Mass General Brigham demonstrated the use of deep brain stimulation (DBS) to map a ‘human dysfunctome’ — a collection of dysfunctional brain circuits associated with different disorders. The team identified optimal networks to target in the frontal cortex that could be used for treating Parkinson’s disease, dystonia, obsessive compulsive disorder (OCD) and Tourette's syndrome. Their results are published in Nature Neuroscience.
“We were able to use brain stimulation to precisely identify and target circuits for the optimal treatment of four different ...
Undiagnosed cancer cases in the US during the first 10 months of the pandemic
2024-02-22
About The Study: This study found that all-sites cancer incidence in the U.S. was significantly lower than expected in March through December 2020, with 134,395 potentially undiagnosed cancer cases. The overall and differential findings can be used to inform where the health care system should be looking to make up ground in cancer screening and detection.
Authors: Krystle A. Lang Kuhs, Ph.D., M.P.H., of the University of Kentucky in Lexington, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamaoncol.2023.6969)
Editor’s ...
Uncorrected refractive error in the African American eye disease study
2024-02-22
About The Study: The results of this study suggest a high burden of refractive error–associated correctable refractive error in African American adults, making it the leading cause of visual impairment in this population. Providing universal coverage for vision care and prescription glasses is an affordable and achievable health care intervention that could reduce the burden of visual impairment in African American adults by over two-thirds and likely raise the quality of life and work productivity, ...
Vision impairment and psychosocial function in older adults
2024-02-22
About The Study: Vision impairment was associated with several psychosocial outcomes, including symptoms of depression and anxiety and social isolation in this study including 2,822 U.S. adults age 65 and older. These findings provide evidence to support prioritizing research aimed at enhancing the health and inclusion of people with vision impairment.
Authors: Pradeep Y. Ramulu, M.D., M.H.S., Ph.D., of the Johns Hopkins University School of Medicine in Baltimore, is the corresponding author.
To access the embargoed ...
Chronic stress spreads cancer … here’s how
2024-02-22
Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes. It may also help cancer spread. How this works has remained a mystery—a challenge for cancer care.
Xue-Yan He, a former postdoc in Cold Spring Harbor Laboratory (CSHL) Adjunct Professor Mikala Egeblad’s lab, says, “Stress is something we cannot really avoid in cancer patients. You can imagine if you are diagnosed, you cannot stop thinking about the disease or insurance ...
Markey study reveals extent of undiagnosed cancer cases due to COVID-19 pandemic
2024-02-22
Over 134,000 cancer cases went undiagnosed in the U.S. during the first 10 months of the COVID-19 pandemic, according to a new University of Kentucky Markey Cancer Center study.
The report published in JAMA Oncology Feb. 22 provides the first estimates of missed cancer diagnoses in 2020 using nationwide surveillance data.
Researchers have expected impacts to cancer detection as a result of delayed screenings and missed health care appointments due to the COVID-19 pandemic, but the extent of this impact had not been quantified until ...
NextGen Precision Health researchers uncover potential treatment for cardiovascular complications from type 2 diabetes
2024-02-22
New research at the Roy Blunt NextGen Precision Health building has discovered a potential treatment for an underlying cause of cardiovascular disease in people with Type 2 diabetes.
More than 30 million Americans live with Type 2 diabetes. One common feature of diabetes is the hardening and inflexibility of blood vessels caused by damage to the endothelial cells in the vascular system. Over time, this can lead to the development and progression of cardiovascular disease, which is the number one cause of death in diabetics. Because endothelial dysfunction is causally linked to cardiovascular disease, there is a considerable ...
Immune cell receptor provides promising immunotherapy target
2024-02-22
FOR IMMEDIATE RELEASE
Drugs that target a receptor on immune cells called activin receptor 1C may combat tumor-induced immune suppression and help patients’ immune systems fight back against cancer, according to a study by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.
The study, published online Jan. 8 in Oncoimmunology, identifies a new strategy cancer cells use to protect themselves from immune system attack, and suggests treatments that could counteract it. It shows that tumor cells and some immune cells produce proteins called activins that ...
Silicon microresonators for artificial neural networks
2024-02-22
Researchers have made significant progress in the development of artificial neural networks using tiny silicon devices called microresonators, paving the way for faster and more energy-efficient artificial intelligence systems. These networks mimic the computing capabilities of the human brain, breaking away from traditional digital computer architectures and leveraging the speed, low power dissipation and multi-wavelength capabilities of photonics.
A review article describing the implementations of neural networks using silicon microresonators was published Jan. 16 in Intelligent Computing, a Science Partner Journal.
Silicon microresonators ...
Scientists develop a simple blood test to quickly diagnose sarcoidosis
2024-02-22
Scientists develop a simple blood test to quickly diagnose sarcoidosis
NIH-funded tool can accurately identify the potentially life-threatening inflammatory disease
A research project supported by the National Institutes of Health has developed a tool to rapidly and inexpensively diagnose sarcoidosis, a chronic inflammatory disease marked by the growth of tiny lumps called granulomas in the lungs and other organs in the body. The tool, which uses a simple blood test, could allow for selective use of more invasive diagnostic tests often used to identify the ...
LAST 30 PRESS RELEASES:
Psilocybin shows context-dependent effects on social behavior and inflammation in female mice modeling anorexia
Mental health crisis: Global surveys expose who falls through the cracks and how to catch them
New boron compounds pave the way for easier drug development
Are cats ‘vegan’ meat eaters? Study finds why isotopic fingerprint of cat fur could trick us into thinking that way
Unexpected partial recovery of natural vision observed after intracortical microstimulation in a blind patient
From sea to soil: Molecular changes suggest how algae evolved into plants
Landmark study to explore whether noise levels in nurseries affect babies’ language development
Everyday diabetes medicine could treat common cause of blindness
Ultra-thin metasurface chip turns invisible infrared light into steerable visible beams
Cluster radioactivity in extreme laser fields: A theoretical exploration
Study finds banning energy disconnections shouldn’t destabilise markets
Researchers identify novel RNA linked to cancer patient survival
Poverty intervention program in Bangladesh may reinforce gender gaps, study shows
Novel approach to a key biofuel production step captures an elusive energy source
‘Ghost’ providers hinder access to health care for Medicaid patients
Study suggests far fewer cervical cancer screenings are needed for HPV‑vaccinated women
NUS CDE researchers develop new AI approach that keeps long-term climate simulations stable and accurate
UM School of Medicine launches clinical trial of investigative nasal spray medicine to prevent illnesses from respiratory viruses
Research spotlight: Use of glucose-lowering SGLT2i drugs may help patients with gout and diabetes take fewer medications
Genetic system makes worker cells more resilient producers of nanostructures for advanced sensing, therapeutics
New AI model can assist with early warning for coral bleaching risk
Highly selective asymmetric 1,6-addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl compounds
Black and Latino teens show strong digital literacy
Aging brains pile up damaged proteins
Optimizing robotic joints
Banning lead in gas worked. The proof is in our hair
Air pollution causes social instability in ant colonies
Why we sleep poorly in new environments: A brain circuit that keeps animals awake
Some tropical land may experience stronger-than-expected warming under climate change
Detecting early-stage cancers with a new blood test measuring epigenetic instability
[Press-News.org] A third of trans masculine individuals on testosterone ovulateStudy from Amsterdam UMC's Center of Expertise on Gender Dysphoria shows that one-third of trans masculine individuals taking testosterone ovulate

