Lowering fecal immunochemical test positivity threshold vs multitarget stool RNA testing for colorectal cancer screening

JAMA

2024-06-01

(Press-News.org) About The Study: This study found that comparable levels of sensitivity and specificity as reported for the multitarget stool RNA (mt-sRNA) test in the colorectal cancer (CRC)-PREVENT study could be achieved by lowering the fecal immunochemical test positivity threshold, without additional mt-sRNA testing. The findings are similar to previous observations for multitarget stool DNA testing.

Corresponding Author: To contact the corresponding author, Hermann Brenner, M.D., M.P.H., email h.brenner@dkfz.de.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2024.9289)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being released to coincide with the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.9289?guestAccessKey=e9d1d41d-b503-4d1c-8d00-6d5666d0c76f&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060124

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[Press-News.org] Lowering fecal immunochemical test positivity threshold vs multitarget stool RNA testing for colorectal cancer screening
JAMA

Lowering fecal immunochemical test positivity threshold vs multitarget stool RNA testing for colorectal cancer screening

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