PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Intoxication without alcohol: Auto-brewery syndrome

2024-06-03
(Press-News.org) How can someone have alcohol intoxication without consuming alcohol? Auto-brewery syndrome, a rare condition in which gut fungi create alcohol through fermentation, is described in a case study in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.231319.

“Auto-brewery syndrome carries substantial social, legal, and medical consequences for patients and their loved ones,” writes Dr. Rahel Zewude, University of Toronto, with coauthors. “Our patient had several [emergency department] visits, was assessed by internists and psychiatrists, and was certified under the Mental Health Act before receiving a diagnosis of auto-brewery syndrome, reinforcing how awareness of this syndrome is essential for clinical diagnosis and management.”

Emergency department (ED), gastroenterology, and infectious disease specialists discuss the case of a 50-year-old woman who had visited the ED at least 7 times for extreme daytime sleepiness and slurred speech and, despite not drinking alcohol, had elevated blood alcohol levels and alcohol on her breath.

She had been on several antibiotic courses for recurrent urinary tract infections alongside a proton pump inhibitor.

At the seventh visit, she was given a possible diagnosis of auto-brewery syndrome, antifungal medication, and referral to a gastroenterologist.

Antifungal medication and low-carbohydrate diets are the main treatment for the condition.

END


ELSE PRESS RELEASES FROM THIS DATE:

HPV-based screening can help eliminate cervical cancer

2024-06-03
Implementing human papillomavirus (HPV)-based screening in British Columbia could eliminate cervical cancer in the province before 2040, according to a modelling study in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.231682. More than 90% of cervical cancer cases worldwide are caused by 9 types of high-risk HPV. The World Health Organization and the Canadian Partnership Against Cancer (CPAC) have both set targets to eliminate cervical cancer by 2040, defined as an annual rate of less than 4 per 100 000 women. The Pap test has been the primary screening ...

New biomarkers will enable personalised influenza vaccination schedule

2024-06-03
Berlin, Germany:  While influenza infection is a significant public health threat, causing serious illness in between three and five million people worldwide per year and leading to about up to 650,000 deaths, the effectiveness of influenza vaccines varies considerably between individuals depending on vaccine types and individual circumstances. A person’s ability to resist infection (host immunity) plays an important role in this. Now, researchers have developed a way of classifying host immunity in individuals, which may lead to the early identification of those who will not respond well to a regular vaccine schedule and therefore ...

Understanding how abnormal embryos self-correct may provide women with a better chance of IVF pregnancy

2024-06-03
Berlin, Germany:  Aneuploidy (the presence of an abnormal number of chromosomes) in embryos is a major cause of impaired embryo development, leading to conditions such as Down syndrome, as well as to pregnancy loss. The transfer of such embryos in women undergoing IVF is therefore usually avoided because of unfavourable pregnancy outcomes. But mosaic embryos, comprising both genetically normal and abnormal cells, can result in perfectly normal babies. Now, researchers have been able to understand how these mosaic ...

Metformin may be as safe as insulin during pregnancy, 11-year data shows

2024-06-02
BOSTON—Metformin is safe to use during pregnancy to manage diabetes, with no long-term adverse effects on the children born and their mothers for at least 11 years after childbirth, according to research presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. This is the first study to look at longer term effects of metformin use during pregnancy. “Metformin has been extensively used for managing raised blood glucose values in pregnancy for many decades now. It is the only blood glucose-lowering oral medication approved ...

Two medication classes reduced cardiovascular and liver events in people with type 2 diabetes

2024-06-02
BOSTON—GLP-1 receptor agonists (GLP-1s) and SGLT-2 inhibitors lower the risk of major cardiovascular events like heart attacks and severe liver complications compared to other diabetes treatments, according to data being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. “Before this study, there was limited information about how these specific diabetes medications work in patients with both type 2 diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD),” said Alexander Kutz, M.D., M.P.H., M.Sc., a research fellow in the Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, at Brigham ...

Neoadjuvant Immunotherapy for early stage melanoma shows positive results

Neoadjuvant Immunotherapy for early stage melanoma shows positive results
2024-06-02
Immunotherapy before surgery for patients with metastatic melanoma appears to be especially successful. Fifty-nine percent of patients responds so well to this therapy that adjuvant treatment is no longer needed, according to the results of the NADINA study that were published today. The NADINA study, led by researchers from the Netherlands Cancer Institute, was named one of the eleven clinical studies with the biggest impact on health care in 2024 by Nature Medicine. The study now proves that this was not an empty claim, as shown by the results presented by medical oncologist and research leader Christian Blank today during ASCO 2024, the international congress ...

CDC reports its decade-long efforts in standardizing vitamin D tests

2024-06-02
BOSTON—Vitamin D tests certified by the U.S. Centers for Disease Control and Prevention (CDC) Clinical Standardization Programs (CSP) are well calibrated overall, according to a new study presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. However, the researchers found some inaccuracies among the assays studied. The blood tests show an “appropriate” level of analytical accuracy, said the study’s lead researcher, Otoe Sugahara, manager of the CDC Vitamin D Standardization-Certification Program (VDSCP) in Atlanta, Ga. Analytical accuracy is the test’s ability to correctly analyze vitamin D in this ...

Persons of nonbinary gender may desire lower-dose testosterone treatment than guidelines recommend

2024-06-02
BOSTON—Among transgender and gender-diverse adults whose gender identity is nonbinary—not exclusively male or female—and who choose low-dose hormone treatment, most prefer to continue testosterone therapy at lower-than-recommended doses after at least six months of treatment, a new study finds. The study will be presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. “Current guidelines for initiation of testosterone for gender affirmation assume that transgender and gender-diverse, or trans, individuals desire both rapid and complete masculinization,” ...

High insulin levels contribute to worse outcomes for Black women with aggressive form of breast cancer

2024-06-02
BOSTON—High insulin levels contribute to worse outcomes for Black women compared to white women who have an aggressive form of breast cancer called triple-negative breast cancer, according to a study presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. Triple-negative breast cancer accounts for about 10-15% of all breast cancers. The term triple-negative breast cancer refers to the fact that the cancer cells do not have estrogen or progesterone receptors and do not make any or too much of the protein called HER2. The cells test ‘negative’ on all 3 tests. Triple-negative breast ...

Stress from living in violent neighborhoods tied to aggressive lung cancer in Black men

2024-06-02
BOSTON—Exposure to increased neighborhood violence has the power to change the glucocorticoid receptor (GR) for the stress hormone, cortisol, which may influence the aggressiveness of lung cancer, according to data presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass. “This research uncovers a previously unknown link between exposure to neighborhood violence, GR and lung tumor aggressiveness that can help us understand and fix the lung cancer health disparity seen in Black men” said Hannah Heath, B.S., a graduate research assistant ...

LAST 30 PRESS RELEASES:

North-south autism assessment divide leaves children waiting three years longer 

Want to publish in Nature? Webinar with Prof. Willie Peijnenburg shares insider tips

Cataract surgery on both eyes can be carried out safely and effectively in one go

Personalized brain stimulation shows benefit for depression

AI uncovers hidden rules of some of nature’s toughest protein bonds

Innovative approach helps new mothers get hepatitis C treatment

Identifying the Interactions That Drive Cell Migration in Brain Cancer

ORNL receives 2025 SAMPE Organizational Excellence Award

University of Oklahoma researchers aim to reduce indigenous cancer disparities

Study reveals new evidence, cost savings for common treatments for opioid use disorder in mothers and infants

Research alert: Frequent cannabis users show no driving impairment after two-day break

Turbulence with a twist

Volcanic emissions of reactive sulfur gases may have shaped early mars climate, making it more hospitable to life

C-Path concludes 2025 Global Impact Conference with progress across rare diseases, neurology and pediatrics

Research exposes far-reaching toll of financial hardship on patients with cancer

The percentage of women who went without a Pap smear for cervical cancer screening increased following the COVID-19 pandemic, from 19% in 2019 to 26% in 2022

AI tools fall short in predicting suicide, study finds

Island ant communities show signs of ‘insect apocalypse’

Revealed: The long legacy of human-driven ant decline in Fiji

Analyzing impact of heat from western wildfires on air pollution in the eastern US

Inadequate regulatory protections for consumer genetic data privacy in US

Pinning down protons in water — a basic science success story

Scientists reveal how the brain uses objects to find direction

Humans sense a collaborating robot as part of their “extended” body

Nano-switch achieves first directed, gated flow of chargeless quantum information carriers

Scientist, advocate and entrepreneur Lucy Shapiro to receive Lasker-Koshland special achievement award

Creating user personas to represent the needs of dementia caregivers supporting medication management at home

UTIA participates in national study analyzing microbial communities, environmental factors impacting cotton development

Mizzou economists: 2025 farm income boosted by high cattle prices and one-time payments

What 3I/ATLAS tells us about other solar systems

[Press-News.org] Intoxication without alcohol: Auto-brewery syndrome