In-hospital delirium and disability and cognitive impairment after COVID-19 hospitalization
JAMA Network Open
2024-07-02
(Press-News.org)
About The Study: In this cohort study of 311 hospitalized older adults with COVID-19, in-hospital delirium was associated with increased functional disability and cognitive impairment over the 6 months following discharge. Older survivors of a COVID-19 hospitalization who experience in-hospital delirium should be assessed for disability and cognitive impairment during postdischarge follow-up.
Corresponding author: To contact the corresponding author, Lauren E. Ferrante, M.D., M.H.S., email lauren.ferrante@yale.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi: 10.1001/jamanetworkopen.2024.19640)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.19640?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=070224
END
ELSE PRESS RELEASES FROM THIS DATE:
2024-07-02
About The Study: In this cross-sectional study, e-cigarette use was independently associated with lower use of lung cancer screening, particularly among individuals who had quit smoking combustible cigarettes. Emerging research suggests that e-cigarettes contain definite and probable carcinogens and cause similar cancer-associated gene deregulations as combustible tobacco.
Corresponding author: To contact the corresponding author, Qian Wang, M.D., M.P.H., email qian.wang@uhhospitals.org.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi: ...
2024-07-02
An experimental study led by Pompeu Fabra University describes the mechanism whereby insulinomas, a rare type of neuroendocrine tumour that affects pancreatic beta cells. According to the study, insulinomas are the result of the accumulation of rare mutations that lead to a homogeneous change in the epigenetic profile of pancreatic beta cells. This profile change causes beta cells to express unusually high levels of oncogenes, growth and transcription factors, and genes related to insulin production.
Insulinomas are rare pancreatic neuroendocrine tumours that involve the excessive growth of beta cells, which are responsible for secreting insulin. Often, they are diagnosed ...
2024-07-02
Scientists at the National Institutes of Health (NIH) have uncovered a brain circuit in primates that rapidly detects faces. The findings help not only explain how primates sense and recognize faces, but could also have implications for understanding conditions such as autism, where face detection and recognition are often impaired from early childhood. The newly discovered circuit first engages an evolutionarily ancient part of the brain called the superior colliculus, which can then trigger the eyes and head to turn for a better look. This better view enables different brain areas in the temporal cortex to engage ...
2024-07-02
UNIVERSITY PARK, Pa. — A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led by researchers at Penn State. They found that disrupting necessary sugar modifications of these proteins promotes cell repair and reverses cellular abnormalities that occur in neurodegenerative diseases.
The study appeared today (July 2) in the journal iScience, and the researchers have a patent related to this work.
“Strategies ...
2024-07-02
Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT). While elevated levels of these enzymes are typically associated with liver and bile duct injuries, subnormal levels can also indicate various pathologies. This review consolidates current knowledge on diseases linked with subnormal liver enzyme levels, focusing on their pathogenesis, specificity, and treatment ...
2024-07-02
Good news for all the treadmill runners who suffer from stubborn and painful shin splints: A little outdoor gait training may help, new research suggests.
A randomized controlled trial found that four weeks of gait training outdoors, in addition to home exercises often prescribed for shin splints, led to improved running biomechanics even when the runners were using a treadmill. These improvements included decreasing the time the runners’ feet were in contact with the ground or treadmill, a recently identified contributor to shin splints.
Based on the trial results, ...
2024-07-02
(Toronto, July 2, 2024) JMIR Publications invites submissions to a new theme issue titled “Patient and Consumer Use of Artificial Intelligence for Health” in its premier open access journal Journal of Participatory Medicine indexed in PubMed, SCOPUS, Sherpa Romeo, and DOAJ.
This theme issue will explore the use of AI for health (AIH) from the perspectives of patients and the public. The journal is seeking papers that examine (a) the experience and impact of patients and health consumers using AI applications, and (b) the involvement of patients, caregivers, and the public in the co-design and development of AIH.
For this theme issue, the journal ...
2024-07-02
In a pioneering study, researchers have completed the chromosome-level genome assemblies for Musa ornata and Musa velutina, shedding light on the genetic underpinnings of pericarp dehiscence and anthocyanin biosynthesis in bananas. This genetic blueprint is poised to revolutionize the enhancement of bananas' ornamental appeal and nutritional quality, unlocking mysteries that were previously obscured by limited genomic data.
Musa ornata and Musa velutina, known for their ornamental appeal, face cultivation challenges ...
2024-07-02
Versatile molecular frameworks called discrete supramolecular structures act like microscopic building blocks customizable for a wide variety of applications. The structures can serve in drug delivery, provide unique environments for catalytic reactions or plug into a molecular machine.
In their paper published June 25 in the Journal of the American Chemical Society, researchers from Yokohama National University presented a new methodology to advance self-assembly of dual-functional supramolecular materials.
Self-assembly involves the spontaneous generation of a well-defined, discrete supramolecular architecture from ...
2024-07-02
COLUMBUS, Ohio – A new study in mice hints at the promise of an eventual alternative treatment option for the “wet” version of age-related macular degeneration (AMD).
Researchers determined in mice that an enzyme related to cell growth and division is a culprit in the blood vessel invasion in the back of the eye that causes blurred central vision in wet AMD. Targeting the enzyme, called telomerase, with an experimental drug suppressed abnormal vascular growth in the animals’ retina.
The only current treatment for wet AMD is injection into the eye of a medication that blocks the activity of a growth factor protein, called VEGF, which is ...
LAST 30 PRESS RELEASES:
[Press-News.org] In-hospital delirium and disability and cognitive impairment after COVID-19 hospitalization
JAMA Network Open
