Progression from pre-symptomatic to clinical type 1 diabetes after COVID-19 infection

JAMA

2024-07-15

(Press-News.org) About The Study: Follow-up of youth with pre-symptomatic type 1 diabetes demonstrated that the COVID-19 pandemic was associated with an accelerated progression to clinical disease and that this acceleration was confined to those with COVID-19. Further studies are required to determine whether COVID-19 also accelerates progression to type 1 diabetes in adults and whether vaccination and monitoring for COVID-19 symptoms should be considered for individuals with pre-symptomatic type 1 diabetes.

Corresponding Author: To contact the corresponding author, Anette-Gabriele Ziegler, M.D., email anettegabriele.ziegler@helmholtz-munich.de.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2024.11174)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.11174?guestAccessKey=26c76ca0-e27f-4e62-8c40-fc63e2f9bba9&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=071524

END

ELSE PRESS RELEASES FROM THIS DATE:

Mental health of transgender youth following gender identity milestones by level of family support

2024-07-15

About The Study: The results of this study demonstrate that without a supportive family environment, gender identity development increases the risk of transgender youth attempting suicide or running away from home. Social services and community resources to establish supportive relationships between transgender children and their parents are essential. Corresponding Author: To contact the corresponding author, Travis Campbell, Ph.D., email campbelt1@sou.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamapediatrics.2024.2035) Editor’s ...

Use of massage therapy for pain

2024-07-15

About The Study: This study found that despite a large number of randomized clinical trials, systematic reviews of massage therapy for painful adult health conditions rated a minority of conclusions as moderate-certainty evidence and that conclusions with moderate- or high-certainty evidence that massage therapy was superior to other active therapies were rare. Corresponding Author: To contact the corresponding author, Selene Mak, Ph.D., M.P.H., email selene.mak@va.gov. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.22259) Editor’s ...

Substantia nigra pathology, contact sports play, and parkinsonism in chronic traumatic encephalopathy

2024-07-15

About The Study: In this cross-sectional study of contact sports athletes with chronic traumatic encephalopathy (CTE), years of contact sports participation were associated with substantia nigra tau pathology and neuronal loss, and these pathologies were associated with parkinsonism. Repetitive head impacts may incite neuropathologic processes that lead to symptoms of parkinsonism in individuals with CTE. Corresponding Authors: To contact the corresponding authors, email Ann C. McKee, M.D. (amckee@bu.edu) and Thor D. Stein, M.D., Ph.D. (tdstein@bu.edu). To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaneurol.2024.2166) Editor’s ...

Early life antibiotic increases risk of asthma: providing clues to a potential prevention adult asthma

2024-07-15

WHY EARLY LIFE ANTIBIOTIC USE CAN INCREASE RISK OF ASTHMA: A POTENTIAL PREVENTION FOR ASTHMA LATER IN LIFE? Early exposure to antibiotics can trigger long term susceptibility to asthma, according to new research from Monash University. Importantly the research team isolated a molecule produced by gut bacteria that in the future could potentially be trialed as a simple treatment, in the form of a dietary supplement, for children at risk of asthma to prevent them developing the disease. Asthma affects over 260 million people globally and causes ...

Tell-tale gene affects success of drug used to treat chronic pain

2024-07-15

Women who carry a particular form of a pain gene are more likely to respond well to a common medication used to treat long-term discomfort, research shows. In a study, women with chronic pelvic pain who had a naturally occurring variation of a gene, known as Neuregulin 3, in their DNA were more likely to experience relief after taking the painkilling drug gabapentin. Targeting gabapentin use to those with this genetic marker would avoid ineffective treatment and unwanted side-effects in those who are unlikely to respond, experts say. The findings could improve use of gabapentin in treating chronic pelvic pain – a persistent, disabling ...

Study reveals how an anesthesia drug induces unconsciousness

2024-07-15

There are many drugs that anesthesiologists can use to induce unconsciousness in patients. Exactly how these drugs cause the brain to lose consciousness has been a longstanding question, but MIT neuroscientists have now answered that question for one commonly used anesthesia drug. Using a novel technique for analyzing neuron activity, the researchers discovered that the drug propofol induces unconsciousness by disrupting the brain’s normal balance between stability and excitability. The drug causes brain activity to become increasingly unstable, until the brain loses consciousness. “The brain has to operate on this knife’s ...

Existence of lunar lava tube cave demonstrated

2024-07-15

A team of international scientists, under the lead of the University of Trento, Italy, has published a research study that has made a milestone discovery on the Moon knowledge. For the first time, scientists have demonstrated the existence of a tunnel in the lunar subsurface. It seems to be an empty lava tube. The research study was published by Nature Astronomy and is the result of an international collaboration. "These caves have been theorized for over 50 years, but it is the first time ever that we have demonstrated their existence," ...

Wyss Institute research collaboration awarded ARPA-H agreement to develop disease-agnostic immunotherapeutic RNA platform

2024-07-15

By Benjamin Boettner With the award for up to $27 million from the Advanced Research Projects Agency for Health (ARPA-H), a collaborative research project at the Wyss Institute for Biologically Inspired Engineering at Harvard University will advance a disease-agnostic novel RNA therapeutic with the potential to treat diverse diseases, and to be effectively and rapidly deployable. By safely and naturally stimulating the “innate immune” system — the body’s first line of defense against ...

A stochastic modeling approach for interplanetary supply chain planning

2024-07-15

First of all, the problem scope and the theoretical foundation are presented. The considered ISC network is a layered network in which nodes represent points of interactions between the two layers. The two interacting networks are PN which delivers cargo from Earth to Mars and SN that is responsible for the propellant supply along the way, respectively. They share the same nodes but comprise different arcs based on their distinct purposes. The nodes are defined as surface nodes (celestial bodies ...

When certain boys feel their masculinity is threatened, aggression ensues

2024-07-15

It’s been long established that certain men become aggressive when they see their manhood as being threatened. When does this behavior emerge during development—and why? A new study by a team of psychology researchers shows that adolescent boys may also respond aggressively when they believe their masculinity is under threat—especially boys growing up in environments with rigid, stereotypical gender norms. The findings, reported in the journal Developmental Science, underscore the effects of social pressure that many boys face to be stereotypically masculine. “We know that not all men respond aggressively to manhood threats—in ...

A CRISPR screen reveals many previously unrecognized genes required for brain development and a new neurodevelopmental disorder

Why Some Bacteria Survive Antibiotics and How to Stop Them - New study reveals that bacteria can survive antibiotic treatment through two fundamentally different “shutdown modes”

Progression from pre-symptomatic to clinical type 1 diabetes after COVID-19 infection

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: