Molecular, socioeconomic, and clinical factors affecting racial and ethnic disparities in colorectal cancer survival

JAMA Oncology

2024-09-12

(Press-News.org) About The Study: This single-center cohort study identified substantial overall survival disparity and differing frequencies of driver gene variations by race and ethnicity. Socioeconomic status had the largest contribution but accounted for less than one-third of the disparity, with substantial contribution from tumor molecular features. Further study of the associations of genetic ancestry and the molecular pathogenesis of colorectal cancer with chemotherapy response is needed.

Corresponding Author: To contact the corresponding author, John Paul Shen, MD, email jshen8@mdanderson.org.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaoncol.2024.3666)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Molecular, socioeconomic, and clinical factors affecting racial and ethnic disparities in colorectal cancer survival

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