PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Estimated long-term benefits of finerenone in heart failure

JAMA Cardiology

2024-09-27
(Press-News.org) About The Study: In this prespecified secondary analysis of the FINEARTS-HF randomized clinical trial, long-term treatment with the nonsteroidal mineralocorticoid receptor antagonist finerenone was estimated to extend event-free survival by up to 3 years among people with heart failure with mildly reduced or preserved ejection fraction. 

Corresponding Author: To contact the corresponding author, Scott D. Solomon, M.D., email ssolomon@rics.bwh.harvard.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

(doi:10.1001/jamacardio.2024.3782)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

#  #  #

Media advisory: This study is being presented at the Heart Failure Society of America Annual Scientific Meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2024.3782?guestAccessKey=01d86985-5893-4796-8f83-807d6b7a02db&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=092724

END


ELSE PRESS RELEASES FROM THIS DATE:

MD Anderson launches first-ever academic journal: Advances in Cancer Education & Quality Improvement

MD Anderson launches first-ever academic journal: Advances in Cancer Education & Quality Improvement
2024-09-27
The University of Texas MD Anderson Cancer Center today announced its first-ever academic journal, Advances in Cancer Education & Quality Improvement (ACE-QI). The journal will publish research, training program summaries and quality improvement interventions for the oncology provider community. The open-access, peer-reviewed journal will feature research and professional perspectives focused on training health care providers to meet myriad challenges around prevention, diagnosis, treatment and survivorship in cancer care. “We envision this journal as a catalyst for critical conversations across the cancer care continuum," said Joshua Kuban, M.D., associate ...

Penn Medicine at the 2024 ASTRO Annual Meeting

2024-09-27
PHILADELPHIA – Leading experts in radiation therapy from Penn Medicine’s Abramson Cancer Center and the Perelman School of Medicine will present new results from clinical trials and research studies at the American Society for Radiation Oncology's (ASTRO) 66th Annual Meeting, which will be held at the Walter E. Washington Convention Center in Washington, D.C., Sept. 29 through Oct. 2, 2024. At the meeting, Neha Vapiwala, MD, FACR, FASTRO, FASCO, the Eli Glatstein Professor in Radiation Oncology, will take office as president-elect of ASTRO as the first Penn faculty member to lead the premier society ...

Head and neck, meningioma research highlights of University of Cincinnati ASTRO abstracts

2024-09-27
University of Cincinnati Cancer Center experts will present research at the American Society for Radiation Oncology (ASTRO) Annual Meeting Sept. 29 through Oct. 2.  Osteoradionecrosis more common in patients with head and neck cancer that requires partial jaw removal  Following radiation treatment for head and neck cancer, some patients can experience osteoradionecrosis (ORN) when an area of exposed bone fails to heal after a three-month period.  “ORN of the mandible and maxilla (jaw bones) can be very debilitating, as it often causes severe pain, fistula formation, infection and susceptibility to fractures,” ...

Center for BrainHealth receives $2 million match gift from Adm. William McRaven (ret.), recipient of Courage & Civility Award

Center for BrainHealth receives $2 million match gift from Adm. William McRaven (ret.), recipient of Courage & Civility Award
2024-09-27
Center for BrainHealth® at The University of Texas at Dallas has received a major match gift commitment from retired U.S. Navy four-star admiral and former University of Texas System chancellor William McRaven and his wife Georgeann. Adm. McRaven recently received the 2024 Bezos Courage & Civility Award presented by Amazon founder Jeff Bezos and Lauren Sánchez.   The $2 million challenge grant will support Optimal BrainHealth for Warfighters – including active-duty military, spouses and veterans. This program will help those with traumatic brain injury (TBI), post-traumatic stress (PTS) and similar issues, as well ...

Circadian disruption, gut microbiome changes linked to colorectal cancer progression

2024-09-27
Irvine, Calif., Sept. 27, 2024 — Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body’s internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the gut microbiome and intestinal barrier function. This discovery offers new avenues for prevention and treatment strategies.   The study, published online today in the journal Science Advances, offers a more comprehensive understanding of how important changes occur in the function and composition of the gut microbiome when the circadian clock is disturbed in the presence ...

Grant helps UT develop support tool for extreme weather events

Grant helps UT develop support tool for extreme weather events
2024-09-27
The University of Tennessee and the UT Institute of Agriculture have received a $434,038 Seeding Solutions grant from the Foundation for Food & Agriculture Research (FFAR) to develop and test a decision support tool for farmers to better manage crop production from risks of extreme weather events across the Tennessee River Basin and surrounding southeast US regions. UT is providing matching funds for a total investment of $966,119 over the three-year project. The U.S. Department of Agriculture estimates that extreme weather is responsible for 90% of crop losses. These estimates are generally based on annual climate conditions. ...

Autonomous vehicles can be imperfect — As long as they’re resilient

Autonomous vehicles can be imperfect — As long as they’re resilient
2024-09-27
Researchers from three of Virginia’s premier universities, including the University of Virginia’s Homa Alemzadeh, aim to take the risk out of self-driving vehicles by overcoming inevitable computer failures with good engineering. The trio will share a $926,737 National Science Foundation award to identify when and where autonomous vehicle systems are most vulnerable to safety-critical failures. They plan to use this knowledge to design ways to efficiently mitigate potential safety hazards and enhance the overall system resilience.  Alemzadeh, an associate professor of electrical and computer engineering in UVA’s School of Engineering and Applied ...

Asteroid Ceres is a former ocean world that slowly formed into a giant, murky icy orb

2024-09-27
Since the first sighting of the first-discovered and largest asteroid in our solar system was made in 1801 by Giuseppe Piazzi, astronomers and planetary scientists have pondered the make-up of this asteroid/dwarf planet. Its heavily battered and dimpled surface is covered in impact craters. Scientists have long argued that visible craters on the surface meant that Ceres could not be very icy.  Researchers at Purdue University and the NASA's Jet Propulsion Lab (JPL) now believe Ceres is a very icy ...

McMaster researchers discover what hinders DNA repair in patients with Huntington’s Disease

2024-09-27
Researchers with McMaster University have discovered that the protein mutated in patients with Huntington’s Disease doesn't repair DNA as intended, impacting the ability of brain cells to heal themselves.    The research, published in PNAS on Sept. 27, 2024, found that the huntingtin protein helps create special molecules that are important for fixing DNA damage. These molecules, known as Poly [ADP-ribose] (PAR), gather around damaged DNA and, like a net, pull in all the factors needed for the repair process. In people with Huntington’s Disease, however, the research found that the mutated version of this protein doesn’t function properly ...

Estrogens play a hidden role in cancers, inhibiting a key immune cell

2024-09-27
DURHAM, N.C. – Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study by Duke Cancer Institute researchers unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other cancers.   Appearing Sept. 27 in the journal Science Advances, the researchers describe how estrogens not only decrease the ability of the immune system to attack tumors, but also reduce the effectiveness of immunotherapies that are used to treat many cancers, notably triple-negative breast cancers. Triple-negative ...

LAST 30 PRESS RELEASES:

The Journal of Nuclear Medicine Ahead-of-Print Tip Sheet: August 1, 2025

Young human blood serum factors show potential to rejuvenate skin through bone marrow

Large language models reshape the future of task planning

Narrower coverage of MS drugs tied to higher relapse risk

Researchers harness AI-powered protein design to enhance T-cell based immunotherapies

Smartphone engagement during school hours among US youths

Online reviews of health care facilities

MS may begin far earlier than previously thought

New AI tool learns to read medical images with far less data

Announcing XPRIZE Healthspan as Tier 5 Sponsor of ARDD 2025

Announcing Immortal Dragons as Tier 4 Sponsor of ARDD 2025

Reporting guideline for chatbot health advice studies

Announcing Mitra Bio as Tier 3 Sponsor of ARDD 2025

Study identifies global upswing in photosynthesis driven by land, offset by oceans

Study reports final clinical trial data for advanced kidney cancer treatment

Antibiotic resistant bacteria found in malnourished children under five years old

Study: Most US homes can save money and affordably weather blackouts with solar plus storage

The human touch of doctors will still be needed in the AI healthcare revolution, technology expert suggests

Helping me, inhibiting you: Analysis of interactions between intestinal microbiota

Hearing loss lowers prospects of employment and higher income for young Americans

Dramatically lower temperature, same high performance!

Trigger warnings fall flat, but safe spaces build trust in the classroom

Searching for a lethal needle in a haystack: synthetic opioid 1000 times more potent than morphine

Smart wound monitor poised to improve chronic infection care

Study reveals spinning could reduce NHS waiting lists for physiotherapy treatments

New AI tool illuminates “dark side” of the human genome

CCNY team discovers potential chemo-induced cognitive changes in cancer survivors

New mRNA-based therapy that shows promise in heart regeneration after heart attack

Extremists use gaming platforms to recruit - study

Nearly 70% of U.S. children in car crashes with a fatality were not using proper child passenger restraints, study finds

[Press-News.org] Estimated long-term benefits of finerenone in heart failure
JAMA Cardiology