International survey of more than 1600 biomedical researchers on the perceived causes of irreproducibility of research results

Integrating data from different experimental approaches into one model is challenging – this study presents a community-based, full-scale in silico model of the rat hippocampal CA1 region that integrates diverse experimental data from synapse to network ##### In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology:   http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002861 Article Title: Community-based reconstruction ...

SAN ANTONIO — November 5, 2024 — Hydrologists at Southwest Research Institute (SwRI) will begin a 12-month targeted water-sampling campaign of the Las Moras Springs system near Brackettville, Texas. The project will analyze and characterize the system of springs and their relationship to the Pinto Creek watershed to improve water management and conservation efforts. “Las Moras, like many other Texas spring systems, are at-risk and prone to going dry. It is important to clear up uncertainties about their source and relationship with ...

Considered one of the fastest-growing agricultural frontiers in Brazil, and the area with the highest greenhouse gas emissions in the Cerrado, Brazil’s savanna-type biome, the region known as MATOPIBA risks facing water shortages in the years ahead. Water overuse may mean that between 30% and 40% of demand for crop irrigation cannot be met in the period 2025-40. MATOPIBA is a portmanteau of the names of four states – Maranhão, Tocantins, Piauí, and Bahia (all but Tocantins located in Brazil’s Northeast ...

Thanks to a 'natural experiment' involving 30,000 people, researchers at Radboud university medical center were able to determine very precisely what an extra year of education does to the brain in the long term. To their surprise, they found no effect on brain structure and no protective benefit of additional education against brain aging. It is well-known that education has many positive effects. People who spend more time in school are generally healthier, smarter, and have better jobs and higher incomes than those with less education. However, whether prolonged education actually causes changes in brain structure over the long term ...

Targeting and customizing blood vessels in tumors to increase T cell infiltration and maintain their function may represent the next breakthrough in cancer therapy. The European Research Council has recognized this by awarding a prestigious Synergy Grant to the project VASC-IMMUNE, where three researchers, each possessing complementary expertise in this research topic, will synergize to advance the field. Professors Anna Dimberg and Magnus Essand are both from the Department of Immunology, Genetics and Pathology, Uppsala University and Professor Thomas Tüting is from the Department of Dermatology, University Hospital Magdeburg. The successful implementation ...

Mosquitoes are much more blunt. Mating occurs for a few seconds in midair. And all it takes to woo a male is the sound of a female’s wingbeats. Imagine researchers’ surprise when a single change completely killed the mosquitoes’ libidos.   Now a study out of UC Santa Barbara reveals that this is really all there is to it. Researchers in Professor Craig Montell’s lab created deaf mosquitoes and found that the males had absolutely no interest in mating. “You could leave them together with the females ...

INDIANAPOLIS – A commentary, published in the Journal of Neurotrauma, calls for traumatic brain injury to be recognized as a chronic condition as are diabetes, asthma, depression and heart failure. To provide comprehensive care for traumatic brain injury throughout individuals’ lifespans, the authors propose that coordinated care models they and others have developed, tested and applied to various populations -- including older adults, individuals living with depression and post-intensive care unit survivors -- be adapted to improve communication and integration between brain injury specialists -- including ...

SAN ANTONIO — November 5, 2024 —Southwest Research Institute’s Dr. James Walker has received the Distinguished Scientist Award from the Hypervelocity Impact Society. This honor recognizes individuals who have made a significant and lasting contribution to the field of hypervelocity science. Hypervelocity impact is typically viewed as impacts at speeds above 2 kilometers per second (4,475 miles per hour); for some materials, however, lower speed impacts display hypervelocity impact effects. The ...

Women with polycystic ovary syndrome (PCOS) and obesity are at a higher risk of giving birth to smaller babies in terms of birth weight, length, and head circumference, according to a recent study conducted at the Norwegian University of Science and Technology (NTNU). One in eight women is affected by the hormone disorder PCOS. Common characteristics are elevated levels of male sex hormones, infrequent or irregular menstrual periods, and the formation of small cysts on the ovaries. In the study, 390 children born to women ...

Researchers are developing new ideas about the best ways to make lab-grown diamonds while minimizing other forms of carbon, such as soot. These diamonds aren’t destined for rings and necklaces, though. These are the kinds that are needed for the computers, optics and sensors of the future.  One new study, conducted by researchers at the U.S. Department of Energy’s (DOE) Princeton Plasma Physics Laboratory (PPPL) and Princeton University, investigated ways to reliably grow diamond at lower temperatures than those currently used. Diamond has properties ...