PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

More than 5 million Americans would be eligible for psychedelic therapy, study finds

As the FDA reviews psilocybin-assisted therapy, Emory’s real-world analysis depicts the public health demand and economic impact based on medical eligibility

More than 5 million Americans would be eligible for psychedelic therapy, study finds
2024-11-12
(Press-News.org)

Acupuncture. Ketamine infusions. “Electroshock” or electroconvulsive therapy. The existing treatment options for those diagnosed with Major Depressive Disorder (MDD) and Treatment-Resistant Depression (TRD), may sometimes feel daunting or expensive alternatives to medication. However, a groundbreaking study from Emory University demonstrates how psilocybin-assisted therapy could impact more than 5 million people in the U.S. pending approval from the FDA.

The findings highlight both the national need for therapies featuring psilocybin, the active ingredient in hallucinogenic mushrooms, as well as the considerations that elected officials, insurance companies, and public health agencies would need to be aware of to successfully roll-out access to psilocybin-assisted therapy (PSIL-AT). 

In the study, researchers used national data from the existing pool of people being treated for MDD and TRD, and applied exclusionary criteria based on comorbidities, such as mania, heart failure, and diabetes, to rule out those who would be medically ineligible for the therapy. These findings indicate that anywhere from 56 to 62% of the individuals being treated for MDD and TRD— roughly 5.1 to 5.6 million people—would be eligible for PSIL-AT and could benefit from it.

“This information is significant because much of the current focus on psychedelic therapies is about its efficacy within clinical trials, and very few people are studying what would be the broader implications of implementing these novel therapeutics,” says Fayzan Rab, lead author of the study and M.D. candidate at Emory University’s School of Medicine. “Our study is one of the first to look at the bigger public health and economic consequences of a world where psilocybin therapy is made more available to Americans.” 

According to Rab, psilocybin-assisted treatment currently has a breakthrough designation with the FDA, meaning that it will expedite a review of the Phase III clinical trial results because of its potential as a therapeutic for depression.

“What is really timely about this research is that it provides a data-driven number that is interpretable to the FDA,” says Rab. “This is how many Americans we think are at stake. I think that will be a meaningful estimate for the FDA to weigh when they consider whether to approve psilocybin for therapeutic use.” 

If approved, private and public insurers such as the Centers for Medicare & Medicaid Services will shape both the demand and the availability of psychedelic therapy. According to the study, almost 20% of the 85 million Medicaid beneficiaries—or 17 million people – are likely to have clinical depression. Therefore, the conditions under which Medicaid might or might not reimburse for psilocybin-assisted therapy will determine the demand.  

A psycho-spiritual model to bring patients to a state of spiritual and mental wellness

An additional prominent attribution to the study is that it is supported by Emory University’s Center for Psychedelics and Spirituality(ECPS), which integrates clinical and research-backed expertise in psychiatry and spiritual health to better understand the therapeutic value of psychedelic medicines. 

George Grant, MDiv, PhD, and co-director of the ECPS, emphasizes that the public health forecast in Rab’s study provides policymakers with an idea of the economic impact, as well as if the treatment will meet the needs of the underserved. 

“Coming to the aid of people who are suffering is very important, and psilocybin-assisted therapy could help people arrive to a place of satisfaction within themselves so that their lives achieve optimal meaning and purpose,” says Grant, also the executive director for Spiritual Health at the Woodruff Health Sciences Center. Regarding the economic impact on the healthcare system, Grant adds, “Psychedelic medicines have promise because the intervention is so fast acting, whereas right now, insurance providers and payers often need to fund the use of antidepressants throughout their lives.” 

Grant is referring to past clinical trials studying the efficacy of psilocybin, which indicate that just one singular 25 mg dose of psilocybin is often enough to reduce symptoms of depression—potentially decreasing the financial burden on insurance payers currently funding other interventions. 

“I am glad to be supported by the Center for Psychedelics and Spirituality, which is an academic environment, providing an objective third-party perspective to policymakers, the FDA, and public health agencies,” says Rab, emphasizing that the study was not done in conjunction with any pharmaceutical agencies. “I am really hopeful that continued research in the area of psychedelic medicine and therapeutics could benefit the millions of Americans that might qualify for it.” 

CITATION: Rab, Syed Fayzan et al. An estimate of the number of people with clinical depression eligible for psilocybin-assisted therapy in the United States. Genomic Press Psychedelics. 13 September 2024.

END


[Attachments] See images for this press release:
More than 5 million Americans would be eligible for psychedelic therapy, study finds More than 5 million Americans would be eligible for psychedelic therapy, study finds 2

ELSE PRESS RELEASES FROM THIS DATE:

Children’s Hospital of Philadelphia researchers find community health workers play critical role in coordinating asthma care across home, school and community

2024-11-12
While great strides have been made to ensure children have access to proper asthma care in their home and community, linking those environments to the care that children receive while in school has been a challenge. In a new study, researchers from Children’s Hospital of Philadelphia (CHOP) demonstrate that community health workers can play a critical role in integrating all environments where children encounter asthma triggers, and care coordination provided by these workers may be a cost-effective way to achieve that. The findings were recently published by JAMA ...

Comprehensive Genomic Profiling leads to better patient outcomes, new joint study says  

2024-11-12
RENTON, Wash. [Nov. 12, 2024] – New real-world data from Providence, Illumina (NASDAQ: ILMN), and Microsoft Research reveals that Comprehensive Genomic Profiling (CGP), when done early in a cancer patient’s diagnosis, leads to better personalized treatment and patient outcomes. The findings come out of the first two years of a five-year, real-world study, which was published today in the Journal of Clinical Oncology - Oncology Practice (JCO-OP).  Through a novel approach, the study employed pathologist-driven CGP testing ...

Animated movie characters with strabismus are more likely to be villains, study finds

2024-11-12
Strabismus, a misalignment of the eyes that occurs especially in children, has no bearing on intelligence or personality, but animated movies tend to use the condition to signify a villainous, dopey, or clumsy character, according to a new study from researchers at the University of Colorado School of Medicine. “When animators are figuring out what a character is going to look like, they have to decide on every little detail of that character's appearance, and so it's not by chance that an animated character happens to have strabismus,” says Michael ...

How retailers change ordering strategy when a supplier starts its own direct channel

2024-11-12
Researchers from Erasmus University and KU Leuven published a new Journal of Marketing study that examines how retailers respond when suppliers establish direct channels to reach end-consumers and how suppliers can take steps to avoid a backlash. The study, forthcoming in the Journal of Marketing, is titled “How Retailers Change Ordering Strategies When Suppliers Go Direct” and is authored by Michiel Van Crombrugge, Els Breugelmans, Femke Gryseels, and Kathleen Cleeren. Recently, Sony began selling PlayStation products through its PlayStation Direct online store in the UK, ...

Young coral use metabolic tricks to resist bleaching

Young coral use metabolic tricks to resist bleaching
2024-11-12
Coral larvae reduce their metabolism and increase nitrogen uptake to resist bleaching in high temperatures, according to a study published November 12th in the open-access journal PLOS Biology by Ariana S. Huffmyer of the University of Washington, US, and colleagues. High ocean temperatures cause coral bleaching, which results from the disruption of the relationship between corals and their symbiotic algae, an increasing concern as global temperatures rise. However, relatively little research has examined the effects of high temperatures ...

Protecting tax whistleblowers pays off

2024-11-12
AUSTIN, Texas — The federal tax gap — money people and companies owe Uncle Sam but fail to pay on time — has climbed to historic highs: $696 billion in 2022, according to the IRS. It’s money that, if recouped, could fund infrastructure or education or pay down government debt. One way to collect that money is through lawsuits prompted by corporate whistleblowers — often present or former employees who know a company’s finances and expose its transgressions. Federal law includes ...

Bioluminescent proteins made from scratch enable non-invasive, multi-functional biological imaging

Bioluminescent proteins made from scratch enable non-invasive, multi-functional biological imaging
2024-11-12
Bioluminescence is the natural chemical process of light creation in some living creatures that makes fireflies flicker and some jellyfish glow. Scientists have long been interested in borrowing the secrets of these animals' light-producing genes to create similar effects in vertebrates, for a variety of biomedical applications. UC Santa Cruz Assistant Professor of Biomolecular Engineering Andy Yeh is designing completely artificial proteins that produce bioluminescence to serve as a non-invasive method for bioimaging, diagnostics, drug discovery, and more. A new paper published in the flagship journal Chem reports on a new series of bioluminescent ...

New study links air pollution with higher rates of head and neck cancer

2024-11-12
DETROIT — A recent study published in the journal Scientific Reports correlates higher levels of pollutant particulate matter to higher occurrences of head and neck aerodigestive cancer. The article, "Air Pollution Exposure and Head and Neck Cancer Incidence," is the work of a multi-institutional collaboration with researchers from Wayne State University, Johns Hopkins University and Mass General Brigham. The study was led by John Cramer, Ph.D., associate professor of otolaryngology, and John Peleman, M.D., medical resident in the Department of Otolaryngology, in the Wayne State University School of Medicine. They collaborated with Mass General Brigham, an integrated ...

LSU researchers excavate earliest ancient Maya salt works

LSU researchers excavate earliest ancient Maya salt works
2024-11-12
The team was led by LSU Alumni Professor Heather McKillop, who first discovered wooden buildings preserved there below the sea floor, along with associated artifacts, and the only ancient Maya wooden canoe paddle in 2004. Her key collaborator, Assistant Professor Elizabeth Sills at the University of Texas at Tyler, began working with McKillop as a master’s student and then as a doctoral student at LSU. Since their initial discovery of wood below the sea floor in Belize, the team has uncovered an extensive pattern of sites that include “salt kitchens” for boiling ...

Building a diverse wildland fire workforce to meet future challenges

2024-11-12
Every year around this time, California’s wildland firefighters hold their breath as hot, dry winds threaten to spread flames across the state. As such conflagrations grow in size and severity throughout the Western U.S., the strain on fire managers has intensified. A new report from Stanford University’s Climate and Energy Policy Program provides a blueprint for fostering a more inclusive, diverse and well-supported workforce to meet the increasing need for fire mitigation and management. “The wellbeing of the wildland fire workforce has ...

LAST 30 PRESS RELEASES:

Community partners key to success of vaccine clinic focused on neurodevelopmental conditions

Low-carbon collaborative dual-layer optimization for energy station considering joint electricity and heat demand response

McMaster University researchers uncover potential treatment for rare genetic disorders

The return of protectionism: The impact of the Sino-US trade war

UTokyo and NARO develop new vertical seed distribution trait for soybean breeding

Research into UK’s use of plastic packaging finds households ‘wishcycle’ rather than recycle – risking vast contamination

Vaccine shows promise against aggressive breast cancer

Adverse events affect over 1 in 3 surgery patients, US study finds

Outsourcing adult social care has contributed to England’s care crisis, argue experts

The Lancet: Over 800 million adults living with diabetes, more than half not receiving treatment, global study suggests

New therapeutic approach for severe COVID-19: faster recovery and reduction in mortality

Plugged wells and reduced injection lower induced earthquake rates in Oklahoma

Yin selected as a 2024 American Society of Agronomy Fellow

Long Covid could cost the economy billions every year

Bluetooth technology unlocks urban animal secrets

This nifty AI tool helps neurosurgeons find sneaky cancer cells

Treatment advances, predictive biomarkers stand to improve bladder cancer care

NYC's ride-hailing fee failed to ease Manhattan traffic, new NYU Tandon study reveals

Meteorite contains evidence of liquid water on Mars 742 million years ago

Self-reported screening helped reduce distressing symptoms for pediatric patients with cancer

Which risk factors are linked to having a severe stroke?

Opening borders for workers: Abe’s profound influence on Japan’s immigration regime

How skills from hospitality and tourism can propel careers beyond the industry

Research shows managers of firms handling recalls should review media scrutiny before deciding whether to lobby

New model system for the development of potential active substances used in condensate modifying drugs

How to reduce social media stress by leaning in instead of logging off

Pioneering research shows sea life will struggle to survive future global warming

In 10 seconds, an AI model detects cancerous brain tumor often missed during surgery 

Burden of RSV–associated hospitalizations in US adults, October 2016 to September 2023

Repurposing semaglutide and liraglutide for alcohol use disorder

[Press-News.org] More than 5 million Americans would be eligible for psychedelic therapy, study finds
As the FDA reviews psilocybin-assisted therapy, Emory’s real-world analysis depicts the public health demand and economic impact based on medical eligibility