PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Repurposing semaglutide and liraglutide for alcohol use disorder

JAMA Psychiatry

2024-11-13
(Press-News.org) About The Study: Among patients with alcohol use disorder (AUD) and comorbid obesity/type 2 diabetes, the use of semaglutide and liraglutide were associated with a substantially decreased risk of hospitalization due to AUD. This risk was lower than that of officially approved AUD medications. Semaglutide and liraglutide may be effective in the treatment of AUD, and clinical trials are urgently needed to confirm these findings. 

Corresponding Author: To contact the corresponding author, Markku Lähteenvuo, MD, PhD, email markku.lahteenvuo@uef.fi.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(10.1001/jamapsychiatry.2024.3599)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamapsychiatry/fullarticle/10.1001/jamapsychiatry.2024.3599?guestAccessKey=4bf50b14-c77f-4a44-9a4f-0b52c5fd0f9b&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=111324

END


ELSE PRESS RELEASES FROM THIS DATE:

IPK-led research team provides insights into the pangenome of barley

2024-11-13
Reliable crop yields fueled the rise of human civilizations. As people embraced a new way of life, cultivated plants, too, had to adapt to the needs of their domesticators. There are different adaptive requirements in a wild compared to an arable habitat. Crop plants and their wild progenitors differ, for example, in how many vegetative branches they initiate or how many seeds or fruits they produce and when. A common concern among crop conservationists is dangerously reduced genetic diversity in cultivated plants. But crop evolution needs not be a unidirectional loss of diversity. “Our panel of 1,000 plant genetic ...

New route to fluorochemicals: fluorspar activated in water under mild conditions

2024-11-13
Researchers at Oxford University have developed a new method to extract fluorine from fluorspar (CaF₂) using oxalic acid and a fluorophilic Lewis acid in water under mild reaction conditions. This technology enables direct access to fluorochemicals, including commonly used fluorinating agents, from both fluorspar and lower-grade metspar, eliminating reliance on the supply chain of hazardous hydrogen fluoride (HF). The findings are published today in the journal Nature. Currently, all fluorochemicals – critical for many industries – are generated from the highly dangerous mineral acid ...

Microbial load can influence disease associations

Microbial load can influence disease associations
2024-11-13
In sickness or in health, the billions of microorganisms that inhabit our guts are our constant companions throughout life. In the past few decades, scientists have shown how the nature of this ‘microbiome’ can provide valuable clues to human diseases and their treatment.  A new study from the Bork group at EMBL Heidelberg, recently published in the journal Cell, reports that a number of conditions, such as lifestyle and disease, affect the total number of microbes in the gut, making this often neglected metric one that bears ...

Three galactic “red monsters” in the early Universe

Three galactic “red monsters” in the early Universe
2024-11-13
An international team led by the University of Geneva (UNIGE) has identified three ultra-massive galaxies – nearly as massive as the Milky Way – already in place within the first billion years after the Big Bang. This surprising discovery was made possible by the James Webb Space Telescope's FRESCO program, which uses the NIRCam/grism spectrograph to measure accurate distances and stellar masses of galaxies. The results indicate that the formation of stars in the early Universe was far more efficient than previously thought, challenging existing galaxy formation models. The study is published in Nature. In the theoretical model favored by scientists, galaxies form ...

First ever study finds sexual and gender minority physicians and residents have higher levels of burnout, lower professional fulfillment

2024-11-13
EMBARGOED by JAMA Network Open until 11 a.m., ET until Nov. 13, 2024 Contact: Gina DiGravio, 617-358-7838, ginad@bu.edu   (Boston)—Burnout is a public health crisis that affects the well-being of physicians and other healthcare workers, and the populations they serve. Burnout is characterized by emotional exhaustion, cynicism, lack of motivation, and feelings of ineffectiveness and inadequate achievement at work. Past studies have shown that compared to the general working U.S. population, physicians ...

Astronomers discover mysterious ‘Red Monster’ galaxies in the early Universe

Astronomers discover mysterious ‘Red Monster’ galaxies in the early Universe
2024-11-13
An international team that was led by the University of Geneva (UNIGE) and includes Professor Stijn Wuyts from the University of Bath in the UK has identified three ultra-massive galaxies – each nearly as massive as the Milky Way – that had already assembled within the first billion years after the Big Bang. The researchers’ results indicate that the formation of stars in the early Universe was far more efficient than previously thought, challenging existing galaxy formation models. The surprising discovery – described today in the journal Nature – was made by the James Webb Space Telescope (JWST) ...

The secrets of fossil teeth revealed by the synchrotron: a long childhood is the prelude to the evolution of a large brain

The secrets of fossil teeth revealed by the synchrotron: a long childhood is the prelude to the evolution of a large brain
2024-11-13
The secrets of fossil teeth revealed by the synchrotron: a long childhood is the prelude to the evolution of a large brain Could social bonds be the key to human big brains? A study of the fossil teeth of early Homo from Georgia dating back 1.77 million years reveals, thanks to the European Synchrotron (ESRF) in Grenoble, a prolonged childhood despite a small brain and an adulthood comparable to that of the great apes. This discovery suggests that an extended childhood, combined with cultural transmission ...

Obesity-fighting drugs may reduce alcohol consumption in individuals with alcohol use disorder

2024-11-13
A new joint study by the University of Eastern Finland and Karolinska Institutet in Sweden found that the GLP-1 agonists semaglutide and liraglutide, which are used for treating diabetes and obesity, were associated with fewer hospitalisations among individuals with alcohol use disorder, AUD. Fewer hospitalisations were observed for alcohol related causes, substance use related causes, and for physical illnesses. However, no association was observed for hospitalisations due to attempted suicide. Effective treatments for alcohol dependence exist; however, they remain underused and are not effective, or suitable, for all patients with alcohol or substance use disorder. Previous ...

Does AI improve doctors’ diagnoses? Study puts it to the test

Does AI improve doctors’ diagnoses? Study puts it to the test
2024-11-13
With hospitals already deploying artificial intelligence to improve patient care, a new study has found that using Chat GPT Plus does not significantly improve the accuracy of doctors’ diagnoses when compared with the use of usual resources.  The study, from UVA Health’s Andrew S. Parsons, MD, MPH and colleagues, enlisted 50 physicians in family medicine, internal medicine and emergency medicine to put Chat GPT Plus to the test. Half were randomly assigned to use Chat GPT Plus to diagnose complex cases, while the other half relied on conventional methods such as medical reference sites (for example, UpToDate©) and Google. The researchers then compared the resulting ...

Extreme weather accelerates nitrate pollution in groundwater

Extreme weather accelerates nitrate pollution in groundwater
2024-11-13
Extreme weather spurred by climate change, including droughts and heavy rains, may increase the risk of nitrates from fertilizers ending up in groundwater, according to a recent study from researchers at the University of California, Davis. The study found heavy rains after a drought caused nitrates to seep 33 feet under farm fields in as little as 10 days. The study was published in Water Resources Research.  “The conventional wisdom was that it could take several weeks to years for nitrates to move from the crop root zones to reach groundwater,” said corresponding author Isaya Kisekka, a professor in the Departments ...

LAST 30 PRESS RELEASES:

Discovery explains kidney damage caused by blood pressure drugs

NYU Langone performs world’s first fully robotic double lung transplant

APSS accepting sleep and circadian research abstracts and session proposals for SLEEP 2025 in Seattle

DNA repair: A look inside the cell’s ‘repair café’

Astronomers take the first close-up picture of a star outside our galaxy

Here’s something Americans agree on: Sports build character

Engineering nature’s blueprint: Dendron-based assemblies for chlorophyll’s materials

Study reveals how cell types shape human brain networks

New genetic explanation for heart condition revealed

Poor mental health linked to browsing negative content online

People with migraine at high risk of depression during pandemic

Climate-driven hazards increases risk for millions of coastal residents, study finds

Females sleep less, awaken more frequently than males

Most Americans want primary care providers to address mental health

Millions of Americans hurt by others’ drinking, drug use: study

Plasma-derived atomic hydrogen advances low-temperature CO2 methanation at high yield

Photon qubits challenge AI, enabling more accurate quantum computing without error-correction techniques

Single gene causes embryo notochord deformity in zebrafish

Sylvester Cancer Tip Sheet - Nov 2024

AI speaks volumes when it comes to detecting Parkinson’s disease

Signals of inflammation during pregnancy linked to aging and memory changes 50 years later

Two million ex-smokers currently vape in England

When trees 'talk:' Researchers probe ancient wood for clues about massive solar storms

High nurse and doctor turnover linked to increased patient deaths in NHS hospitals

History of endometriosis and fibroids linked to heightened risk of early death

High nurse and doctor turnover rates linked to increased patient deaths in NHS hospitals

Research highlights the pressures human activities place on tropical marine ecosystems

New research sets out how to make free internet access a human right

Argonne plays critical role in assessing small modular reactor applications to rebuild a clean economy in post-war Ukraine

In the ‘Wild West’ of AI chatbots, subtle biases related to race and caste often go unchecked

[Press-News.org] Repurposing semaglutide and liraglutide for alcohol use disorder
JAMA Psychiatry