Allostatic load, educational attainment, and risk of cancer mortality among us men

JAMA Network Open

2024-12-10

(Press-News.org) About The Study: This study highlights the detrimental association of not attaining a high school degree, combined with high allostatic load as a marker of chronic stress, with cancer mortality. Efforts to promote educational attainment and address the underlying social determinants of health are imperative in reducing cancer disparities in this population.

Corresponding Author: To contact the corresponding author, Justin X. Moore, PhD, MPH, email jx.moore@uky.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2024.49855)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.49855?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=121024

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Flaw in computer memory leads to global security fixes

2024-12-10

Cyber security experts studying memory modules in computers have uncovered a key security weakness that has led to worldwide security fixes in AMD computer processors. The weakness occurs because of ‘BadRAM’ - rogue memory modules that deliberately provide false information to the computer’s processor during startup. Processors are present in every computer and are necessary to perform every calculation. The computer’s memory (DRAM) is essential for storing code and data. When a computer ...

Race, ethnicity, and sleep in us children

2024-12-10

About The Study: In this cross-sectional study of children’s sleep disparities, racially and ethnically minoritized children exhibited disparities in mean levels and variability of sleep compared with their white peers. These findings suggest that policies and practices should target multiple sleep dimensions among diverse racial and ethnic groups to promote equitable pediatric sleep health. Corresponding Author: To contact the corresponding author, Yijie Wang, PhD, email yjwang@msu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.49861) Editor’s ...

Geriatric surgery verification program can improve outcomes for older cancer patients in community hospitals

2024-12-10

Key takeaways The American College of Surgeons Geriatric Surgery Verification program significantly decreases hospital stays among older cancer patients, according to researchers who implemented the program at their institution. After implementing the program, patients undergoing major abdominal oncologic procedures also maintained higher levels of independence and were more likely to be discharged home. Researchers found the program addresses the unique needs of older cancer patients by focusing on multiple aspects of care. CHICAGO — ...

Pew funds 8 teams to conduct collaborative biomedical research

2024-12-10

PHILADELPHIA—The Pew Charitable Trusts announced today the eight pairs of researchers who will make up its 2024 class of Innovation Fund investigators. These 16 acclaimed scientists—all alumni of Pew’s biomedical programs in the United States and Latin America—will collaborate on interdisciplinary research projects that explore foundational questions about human biology and disease. By combining their expertise in topic areas ranging from cell biology and immunology to neuroscience and genetics, these partnerships will help to advance scientific discovery and improve human ...

Finding innovative ways to address kidney cancer leads to DoD grant

2024-12-10

Weill Cornell Medicine has received a $1.4 million, four-year grant from the U.S. Department of Defense to investigate a new therapeutic approach for the most common form of kidney cancer. The grant is one of 10 Idea Awards the department funded this year to support innovative, high-risk, high-reward science that could lead to a paradigm shift in cancer care. The funding will enable principal investigators Dr. Lorraine Gudas and Dr. David Nanus to explore a cellular reprogramming strategy that may improve how patients ...

Americans are uninformed about and undervaccinated for HPV

2024-12-10

LOS ANGELES — The human papillomavirus (HPV), a common sexually transmitted infection, accounts for 70% of all throat cancers, according to the National Cancer Institute. While commonly associated with cervical cancer, throat cancer is now the most common type of HPV-related cancer. However, the majority of American adults are unaware that HPV can cause throat cancer and are not taking advantage of the one proven method for prevention — the HPV vaccine. These are the conclusions of two recent studies from the USC Head and Neck Center, part of Keck Medicine of USC and the USC Caruso Department of Otolaryngology – ...

KTU scientists developed a nanolaser: silver nanocubes enable light generation

2024-12-10

Kaunas University of Technology (KTU), Lithuania researchers and scientists from Japan have developed a unique nanolaser. Although the dimensions of this laser are so small that its structure can only be seen through a powerful microscope, its potential is vast. With applications in early medical diagnostics, data communication, and security technologies, this invention could also become a key tool for the study of light and matter interactions. Depending on the application, lasers differ in the way light is amplified and produced, which determines the colour of the radiation and the quality of the laser ...

Insilico Medicine nominates orally available pre-clinical candidate targeting NLRP3 to treat inflammation and central nervous system diseases

2024-12-10

As the first line against microbial infections or endogenous cellular damage in our body, the innate immune system utilizes NLRs (NOD-like receptors) to sense the molecules triggering microbial infection and damage, thus ensuring the proper immune response function. In the NLRs family, NLRP3 is the most characterized member, and its overactivation can lead to excessive production of pro-inflammatory cytokines and chemokines, driving pathological processes in various inflammatory diseases. CAMBRIDGE, Mass., Dec 10, 2024 --- Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven drug discovery ...

PLOS receives $3.3 million grant to support Open Access publishing & business model transformation

2024-12-10

SAN FRANCISCO — FOR IMMEDIATE RELEASE PLOS has been awarded a $3.3million grant from the Bill & Melinda Gates Foundation, underscoring its commitment to pioneer a shift away from traditional publishing models. The 3-year funding package from the Gates Foundation will support PLOS’ transition towards APC-free publishing by enabling authors, funded by the foundation, to publish with PLOS without facing APC barriers, and to contribute to open access publishing options for authors who do not have access to funding. This 3-year grant offers support while PLOS is actively working on new publishing models grounded in open science starting with ...

HBx facilitates drug resistance in hepatocellular carcinoma via CD133-regulated self-renewal of liver cancer stem cells

2024-12-10

Background and Aims Hepatitis B virus (HBV) infection contributes to hepatocellular carcinoma (HCC) tumorigenesis, drug resistance, and recurrence, although the underlying molecular mechanisms remain unclear. Recent studies suggest that HBV infection may be associated with liver cancer stem cells (LCSCs), but the exact mechanisms are yet to be resolved. In this study, we aimed to analyze the role of HBV infection in regulating the stemness of HCCs, which is closely linked to drug resistance. Methods Sphere formation assay and real-time Polymerase Chain Reaction quantification were used to ...

Synthesis of seven quebracho indole alkaloids using "antenna ligands" in 7-10 steps, including three first-ever asymmetric syntheses

Lisbon to host world’s largest conference on ecosystem restoration in 2027, led by researcher from the Faculty of Sciences, University of Lisbon

Electrocatalysis with dual functionality – an overview

Scripps Research awarded $6.9 million by NIH to crack the code of lasting HIV vaccine protection

New post-hoc analysis shows patients whose clinicians had access to GeneSight results for depression treatment are more likely to feel better sooner

Bimodal tactile tomography with bayesian sequential palpation for intracavitary microstructure profiling and segmentation

Disrupted connectivity of the brainstem ascending reticular activating system nuclei-left parahippocampal gyrus could reveal mechanisms of delirium following basal ganglia intracerebral hemorrhage

[Press-News.org] Allostatic load, educational attainment, and risk of cancer mortality among us men
JAMA Network Open

Allostatic load, educational attainment, and risk of cancer mortality among us men

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: