Development and validation of a tool to predict onset of mild cognitive impairment and Alzheimer dementia

JAMA Network Open

2025-01-08

(Press-News.org) About The Study: In this prognostic study, with the use of a statistical modeling approach, the Florey Dementia Index was developed and validated to predict the onset age of mild cognitive impairment and Alzheimer dementia. This tool may be useful in organizing health care for older adults with cognitive decline or dementia and in the future may help prioritize patients for the use of disease-modifying monoclonal antibody drugs.

Corresponding Authors: To contact the corresponding authors, email Yijun Pan, PhD (yijun.pan@unimelb.edu.au) and Liang Jin, PhD (liang.jin@unimelb.edu.au).

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(doi:10.1001/jamanetworkopen.2024.53756)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Development and validation of a tool to predict onset of mild cognitive impairment and Alzheimer dementia

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