(Press-News.org) About The Study: Following landmark clinical trials and changes in guideline recommendations, self-reported primary prevention aspirin use decreased among older adults and adults with low atherosclerotic cardiovascular disease (ASCVD) risk for whom aspirin was not recommended, but also decreased among adults with higher ASCVD risk for whom aspirin may still be recommended. Despite these reductions, many patients with limited likelihood to benefit reported continuing to take aspirin.
Corresponding Author: To contact the corresponding author, Timothy S. Anderson, MD, MAS, email tsander@pitt.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2024.27333)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
# # #
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2024.27333?guestAccessKey=92514d49-ef8a-4a09-9ce1-7a4d3cefea53&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=012225
END
Trends in preventive aspirin use by atherosclerotic cardiovascular risk
JAMA
2025-01-22
ELSE PRESS RELEASES FROM THIS DATE:
Sex differences in long COVID
2025-01-22
About The Study: This study found that female sex was associated with an increased risk of long COVID compared with male sex, and this association was age, pregnancy, and menopausal status dependent. These findings highlight the need to identify biological mechanisms contributing to sex specificity to facilitate risk stratification, targeted drug development, and improved management of long COVID.
Corresponding author: To contact the corresponding author, Dimpy P. Shah, M.D., Ph.D., email ShahDP@uthscsa.edu.
To ...
Medically recommended vs nonmedical cannabis use among US adults
2025-01-22
About The Study: The results of this study showed that adults ages 18 to 49 reporting medical-only or medical-nonmedical cannabis use vs nonmedical-only use had higher prevalence of cannabis use disorder at all severity levels and reported more frequent cannabis use. These findings suggest that medically recommended cannabis is not associated with reduced addiction risk compared with nonmedical use.
Corresponding author: To contact the corresponding author, Nora D. Volkow, M.D., email nvolkow@nida.nih.gov.
To access the embargoed study: ...
Spanish scientists discover how the gut modulates the development of inflammatory conditions
2025-01-22
A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the intestinal barrier and reach the bone marrow, where they induce epigenetic changes—modifications that alter gene activity without affecting DNA sequence—in the stem cells that give rise to immune cells. The epigenetic changes induced by the translocated gut bacteria generate “trained” immune cells primed to respond more efficiently to future infections. However, this same ability to amplify the immune response can also aggravate the inflammatory conditions such as ...
Compact comb lights the way for next-gen photonics
2025-01-22
In the world of modern optics, frequency combs are invaluable tools. These devices act as rulers for measuring light, enabling breakthroughs in telecommunications, environmental monitoring, and even astrophysics. But building compact and efficient frequency combs has been a challenge—until now.
Electro-optic frequency combs, introduced in 1993, showed promise in generating optical combs through cascaded phase modulation but progress slowed down because of their high power demands and limited bandwidth. This led to the field being dominated by femtosecond lasers and Kerr soliton microcombs, which, while effective, require complex tuning and ...
New research reveals how location influences how our immune system fights disease
2025-01-22
Seattle, WASH.—January 22, 2025—The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease. In a new study published in Nature, led by scientists at the Allen Institute, La Jolla Institute for Immunology, and UC San Diego, researchers reveal how cells known as tissue-resident memory CD8 T cells, play unique and specialized roles based on where they are located within the small intestine. Tissue-resident memory cells provide a local first ...
AI in cell research: Moscot reveals cell dynamics in unprecedented detail
2025-01-22
Thanks to a new technology called Moscot (“Multi-Omics Single-Cell Optimal Transport”), researchers can now observe millions of cells simultaneously as they develop into a new organ—for example, a pancreas. This groundbreaking method was developed by an international research team led by Helmholtz Munich and has been published in the renowned journal Nature.
Until now, biologists had only a limited understanding of how cells develop in their natural environment—for instance, when they form an organ in the ...
New study finds social programs could reduce the spread of HIV by 29%
2025-01-22
January 22, 2025
New Study Finds Social Programs Could Reduce the Spread of HIV by 29%
Although HIV was used as a case study, the UMass Amherst researchers say their assessment tool has applications for other diseases
AMHERST, Mass. — Researchers at the University of Massachusetts Amherst have quantified the impacts of a constellation of social factors on the spread of HIV. Their study, published in Health Care Management Science, found that a hypothetical 100% effective intervention addressing barriers to HIV treatment and care from depression, homelessness, ...
SIDS discovery could ID babies at risk of sudden death
2025-01-22
New University of Virginia School of Medicine research revealing the fingerprints of Sudden Infant Death Syndrome within blood samples could open the door to simple tests to identify babies at risk.
The findings also represent an important step forward in unraveling the causes of SIDS, an unexplained condition that is the No. 1 killer of babies between amonth and a year old.
The UVA researchers analyzed blood serum samples collected from infants who died ...
Ozone exposure linked to hypoxia and arterial stiffness
2025-01-22
Ozone (O3) exposure may reduce the availability of oxygen in the body, resulting in arterial stiffening due to the body’s natural response to create more red blood cells and hemoglobin, according to a study published today in JACC, the flagship journal of the American College of Cardiology.
“Researchers found that even brief exposure to elevated ozone levels reduced blood oxygen saturation, triggered hypoxia-related biomarkers, and increased arterial stiffness, highlighting the novel connection between ozone exposure and arterial stiffness, demonstrated through comprehensive biomarker analysis in a high-altitude ...
Princeton Chemistry develops copper-detection tool to discover possible chelation target for lung cancer
2025-01-22
The Chang Lab at Princeton Chemistry continues in its mission to elucidate the role of metal nutrients in human biology: last year, iron; this year, copper. The lab’s first paper of 2025 showcases its development of a revelatory sensing probe for the detection of copper in human cells and then wields it to uncover how copper may be regulating cell growth in lung cancer.
Researchers also offer a possible treatment modality in which copper chelation shows promising results in certain lung cancers where cells have two related phenomena: a heightened transcription factor responding to oxidative stress and a diminished level of bioavailable copper.
Their collaborative paper, A histochemical ...
LAST 30 PRESS RELEASES:
Fat may play an important role in brain metabolism
New study finds no lasting impact of pandemic pet ownership on human well-being
New insights on genetic damage of some chemotherapies could guide future treatments with less harmful side effects
Gut microbes could protect us from toxic ‘forever chemicals’
Novel modelling links sea ice loss to Antarctic ice shelf calving events
Scientists can tell how fast you're aging from a single brain scan
U.S. uterine cancer incidence and mortality rates expected to significantly increase by 2050
Public take the lead in discovery of new exploding star
What are they vaping? Study reveals alarming surge in adolescent vaping of THC, CBD, and synthetic cannabinoids
ECMWF - delivering forecasts over 10 times faster and cutting energy usage by 1000
Brazilian neuroscientist reveals how viral infections transform the brain through microscopic detective work
Turning social fragmentation into action through discovering relatedness
Cheese may really be giving you nightmares, scientists find
Study reveals most common medical emergencies in schools
Breathable yet protective: Next-gen medical textiles with micro/nano networks
Frequency-engineered MXene supercapacitors enable efficient pulse charging in TENG–SC hybrid systems
Developed an AI-based classification system for facial pigmented lesions
Achieving 20% efficiency in halogen-free organic solar cells via isomeric additive-mediated sequential processing
New book Terraglossia reclaims language, Country and culture
The most effective diabetes drugs don't reach enough patients yet
Breast cancer risk in younger women may be influenced by hormone therapy
Strategies for staying smoke-free after rehab
Commentary questions the potential benefit of levothyroxine treatment of mild hypothyroidism during pregnancy
Study projects over 14 million preventable deaths by 2030 if USAID defunding continues
New study reveals 33% gap in transplant access for UK’s poorest children
Dysregulated epigenetic memory in early embryos offers new clues to the inheritance of polycystic ovary syndrome (PCOS)
IVF and IUI pregnancy rates remain stable across Europe, despite an increasing uptake of single embryo transfer
It takes a village: Chimpanzee babies do better when their moms have social connections
From lab to market: how renewable polymers could transform medicine
Striking increase in obesity observed among youth between 2011 and 2023
[Press-News.org] Trends in preventive aspirin use by atherosclerotic cardiovascular riskJAMA