(Press-News.org)
A new study led by researchers from Peking University, published in Health Data Science, reveals a sharp rise in the burden of early-onset type 2 diabetes (T2D) among adolescents and young adults in China from 1990 to 2021. Despite improvements in mortality rates, the incidence and disability-adjusted life years (DALYs) associated with the disease have grown alarmingly.
Using data from the Global Burden of Disease (GBD) Study 2021, the study shows that the age-standardized incidence rate nearly doubled, increasing from 140.20 per 100,000 in 1990 to 315.97 per 100,000 in 2021, with an average annual percentage change (AAPC) of 2.67%. Similarly, DALYs rose from 116.29 to 267.47 per 100,000 during the same period, marking an AAPC of 2.75%. Mortality rates, however, showed only a slight decline.
The burden of early-onset T2D disproportionately affects young males, who experience higher rates of incidence, DALYs, and mortality compared to females. The 15–19 age group witnessed the fastest rise in incidence, with an AAPC of 4.08%, indicating a critical need for age-specific interventions.
The study identifies high body mass index (BMI) as the leading contributor to early-onset T2D DALYs, accounting for 59.85% in 2021, a significant increase from 40.08% in 1990. Other key risk factors include ambient particulate matter pollution and diets high in red meat.
“Our findings underscore the urgent need for comprehensive public health strategies focused on obesity prevention, improved environmental health, and dietary interventions,” said Professor Siyan Zhan from the Department of Epidemiology and Biostatistics, School of Public Health, Peking University.
The researchers emphasize the importance of targeted interventions for males and younger age groups, integrating public awareness campaigns, policy reforms, and community-based health programs to curb the growing disease burden.
This study provides critical evidence to guide policymakers and healthcare professionals in addressing the escalating health challenge posed by early-onset type 2 diabetes in China.
END
NEW YORK, NY (Feb. 5, 2025)--Columbia scientists have found specialized neurons in the brains of mice that order the animals to stop eating.
Though many feeding circuits in the brain are known to play a role in monitoring food intake, the neurons in those circuits do not make the final decision to cease eating a meal.
The neurons identified by the Columbia scientists, a new element of these circuits, are located in the brainstem, the oldest part of the vertebrate brain. Their discovery could lead ...
About The Study: The results of this cluster trial demonstrate that salt substitution was safe, along with reduced risks of stroke recurrence and death, which underscores large health gains from scaling up this low-cost intervention among patients with stroke.
Corresponding Authors: To contact the corresponding authors, email Lijing L. Yan, MPH, PhD, (lijing.yan@duke.edu) and Maoyi Tian, PhD, (maoyi.tian@hrbmu.edu.cn)
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamacardio.2024.5417)
Editor’s Note: Please see the article for additional information, ...
About The Study: This study found that most publicly targeted fatal mass shootings involved multiple types of firearms and handguns were the most common type of firearm present. Assault weapons being present during a publicly targeted mass shooting was associated with a slight increase in the number of injuries and deaths occurring during that incident.
Corresponding Author: To contact the corresponding author, Leslie M. Barnard, MPH, DrPH, email leslie.barnard@ucdenver.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.58085)
Editor’s ...
About The Study: Drug overdose deaths have increased exponentially since 1979. This rate of increase accelerated during the COVID-19 pandemic but has since waned. When comparing recent drug-related mortality rates with their pre-2020 trajectory, the vast majority of states remained higher than expected. In the 4 years between 2020 and 2023, nearly all states had higher drug-related mortality rates than their 2019 rates.
Corresponding Author: To contact the corresponding author, Keith Humphreys, ...
University of Cincinnati experts will present research at the International Stroke Conference 2025 in Los Angeles.
Study finds small number of patients eligible for new ICH treatment
Intracerebral hemorrhage (ICH), when there is bleeding into brain tissue from the rupture of a damaged blood vessel, is one of the most devastating types of stroke. Patients often suffer from severe neurologic disability or even death. There were no proven treatments for patients with ICH until recently.
“We now have one ...
Superconducting materials are similar to the carpool lane in a congested interstate. Like commuters who ride together, electrons that pair up can bypass the regular traffic, moving through the material with zero friction.
But just as with carpools, how easily electron pairs can flow depends on a number of conditions, including the density of pairs that are moving through the material. This “superfluid stiffness,” or the ease with which a current of electron pairs can flow, is a key measure of a material’s superconductivity.
Physicists at MIT and Harvard University have now directly measured superfluid stiffness for the first time ...
In India, many kids who work in retail markets have good math skills: They can quickly perform a range of calculations to complete transactions. But as a new study shows, these kids often perform much worse on the same kinds of problems as they are taught in the classroom. This happens even though many of these students still attend school or attended school through 7th or 8th grades.
Conversely, the study also finds, Indian students who are still enrolled in school and don’t have jobs do better on school-type math problems, but they often fare poorly at the kinds of problems that occur in marketplaces.
Overall, both the “market kids” and the “school kids” ...
UNDER EMBARGO UNTIL 16:00 GMT / 11:00 ET WEDNESDAY 5 FEBRUARY 2025
Quantum algorithm distributed across multiple processors for the first time – paving the way to quantum supercomputers
In a milestone that brings quantum computing tangibly closer to large-scale practical use, scientists at Oxford University Physics have demonstrated the first instance of distributed quantum computing. Using a photonic network interface, they successfully linked two separate quantum processors to form a single, fully connected ...
Antibiotics are indispensable for treating bacterial infections. But why are they sometimes ineffective, even when the bacteria are not resistant? In their latest study published in the journal Nature, researchers from the University of Basel challenge the conventional view that a small subset of particularly resilient bacteria are responsible for the failure of antibiotic therapies.
In certain infectious diseases caused by bacteria, antibiotics are less effective than expected. One example is infections caused by Salmonella bacteria, which can lead to illnesses such ...
Where lies the origin of the Indo-European language family? Ron Pinhasi and his team in the Department of Evolutionary Anthropology at the University of Vienna contribute a new piece to this puzzle in collaboration with David Reich's ancient DNA laboratory at Harvard University. They analyzed ancient DNA from 435 individuals from archaeological sites across Eurasia between 6.400–2.000 BCE. They found out that a newly recognized Caucasus-Lower Volga population can be connected to all Indo-European-speaking populations. The new ...