Cannabis use disorder emergency department visits and hospitalizations and 5-year mortality

JAMA Network Open

2025-02-06

(Press-News.org) About The Study: In this cohort study of all residents of Ontario, Canada, individuals with incident hospital-based cannabis use disorder care were at markedly increased risk of death compared with the general population. These findings suggest important clinical and policy implications, given global trends toward cannabis legalization and market commercialization accompanied by increasing cannabis use and cannabis use disorders.

Corresponding Author: To contact the corresponding author, Daniel T. Myran, MD, MPH, email dmyran@ohri.ca.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2024.57852)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.57852?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=020625

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

COVID-19 pandemic and rates of common ophthalmic procedures among Medicare beneficiaries

2025-02-06

About The Study: The results of this study show that the COVID-19 pandemic caused a notable drop in the number of common ophthalmic procedures among Medicare beneficiaries, especially in laser peripheral iridotomy, while eye drug injections saw minimal changes. The Northeast experienced the largest reductions, highlighting the pandemic’s association with changes in eye care and indicating a need for focused recovery efforts in the hardest hit areas. Corresponding Author: To contact the corresponding author, Jessica D. Randolph, MD, email jessica.randolph@vcuhealth.org. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamaophthalmol.2024.6065) Editor’s ...

Updated drug information handout outdoes FDA’s version

2025-02-06

A clinical trial comparing a one-page medication handout proposed by the U.S. Food and Drug Administration (FDA) with an updated version developed by researchers at the University of Pittsburgh that quantifies a drug’s risk and benefits showed that the latter was more informative and helped patients feel better equipped to make decisions. Published today in JAMA Network Open, the study, which used the drug mifepristone as an example, highlights the importance of communicating risks and benefits of prescription medications – ...

Gemini North teams up with LOFAR to reveal largest radio jet ever seen in the early universe

2025-02-06

From decades of astronomical observations scientists know that most galaxies contain massive black holes at their centers. The gas and dust falling into these black holes liberates an enormous amount of energy as a result of friction, forming luminous galactic cores, called quasars, that expel jets of energetic matter. These jets can be detected with radio telescopes up to large distances. In our local Universe these radio jets are not uncommon, with a small fraction being found in nearby galaxies, but they have remained elusive in the distant, early Universe until now. Using a combination of telescopes, astronomers have discovered a distant, two-lobed radio ...

Researchers discover a major driver of inflammatory pathology in autoimmune and chronic inflammatory diseases

2025-02-06

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that patrols our body, ever vigilant for signs of infection or injury. Now, over 100 years after the complement system was first described, researchers at Mass General Brigham have discovered that a protein known as granzyme K (GZMK) drives tissue damage and inflammation by activating the complement system against our own tissues. Their findings not only reshape the century-old understanding of the complement system but also open new avenues for therapies that could specifically ...

Research in fruit flies pinpoints brain pathways involved in alcohol-induced insomnia

2025-02-06

Alcohol use disorder, which affects over 10% of Americans, can lead to persistent and serious insomnia. Difficulties falling asleep and staying asleep can last even after months of sobriety, increasing the risk of relapse. But treating withdrawal-related insomnia is difficult, partly because what’s going on in the brain in this condition remains largely mysterious. Now, research in fruit flies has identified specific brain signals and groups of brain cells that are involved in alcohol-induced insomnia. This work could ultimately lead ...

Cancer diagnoses and deaths are declining in Appalachia but remain significantly higher compared to other US regions

2025-02-06

Key Takeaways: Appalachia is not uniform: There are important distinctions in cancer diagnoses and deaths among different regions of Appalachia, with certain areas of Central Appalachia experiencing the highest rates of cancer incidence and deaths among the greater Appalachian region. Higher death rates from cancers that can be caught early with screening: Although the region has improved in screening rates, people in Appalachia still die more frequently from cancers that can be caught early with routine screening than elsewhere in the United States. Reason for hope: Research can pave the way for targeted interventions that can reduce these ...

Why some heavy drinkers develop advanced liver disease, while others do not

2025-02-06

LOS ANGELES — Why do some people who consume a few glasses of alcohol a day develop advanced liver disease while others who drink the same amount don’t? The answer may lie in three common underlying medical conditions, according to a new study published in Clinical Gastroenterology and Hepatology from Keck Medicine of USC. The research found that heavy drinkers with either diabetes, high blood pressure or a high waist circumference are as much as 2.4 times more likely to develop advanced liver disease. “The results ...

OmicsFootPrint: Mayo Clinic’s AI tool offers a new way to visualize disease

2025-02-06

ROCHESTER, Minnesota — Mayo Clinic researchers have pioneered an artificial intelligence (AI) tool, called OmicsFootPrint, that helps convert vast amounts of complex biological data into two-dimensional circular images. The details of the tool are published in a study in Nucleic Acids Research. Omics is the study of genes, proteins and other molecular data to help uncover how the body functions and how diseases develop. By mapping this data, the OmicsFootPrint may provide clinicians and researchers with a new way to visualize ...

New genetic mutation linked to drug resistance in non-small cell lung cancer patient

2025-02-06

“Here we present a case of a patient with stage IV CD-74-ROS1 fusion NSCLC discovered initially with RNA next generation sequencing (NGS) who acquired resistance to lorlatinib after 6 months on therapy through a novel RUFY1-RET fusion, detected only through RNA NGS.” BUFFALO, NY - February 6, 2025 – A new case report was published in Volume 16 of Oncotarget on February 5, 2025, titled “Acquired RUFY1-RET rearrangement as a mechanism of resistance to lorlatinib in a patient with CD74-ROS1 rearranged non-small cell lung cancer: A case report." In this case report, Jenny L. ...

Single-photon LiDAR delivers detailed 3D images at distances up to 1 kilometer

2025-02-06

WASHINGTON — Researchers have designed a single-photon time-of-flight LiDAR system that can acquire a high-resolution 3D image of an object or scene up to 1 kilometer away. The new system could help enhance security, monitoring, and remote sensing by enabling detailed imaging even in challenging environmental conditions or when objects are obscured by foliage or camouflage netting. “Our system uses a single-photon detector approximately twice as efficient as detectors deployed in similar LiDAR systems ...

Patients of an online obesity clinic achieved the same weight loss as those in clinical trials of semaglutide – but with much lower doses of the drug

Protein bars enriched with collagen have potential as a weight-loss aid, Spanish study finds

Semaglutide may provide early protection against heart disease in high-risk patients—even before clinically meaningful weight loss and prior to the full target dose

Cannabis use disorder emergency department visits and hospitalizations and 5-year mortality

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: