Risk factors for severe disease among children hospitalized with RSV

JAMA Network Open

2025-04-11

(Press-News.org) About The Study: In this cohort study of children hospitalized with respiratory syncytial virus (RSV) in 2022 and 2023, severe RSV disease was more likely among those age 2 or older with pulmonary and neurologic, neuromuscular, or developmental conditions. For children younger than 2 years, age younger than 6 months and prematurity were the main risk factors. These findings support prevention strategies for all younger children, including premature infants, with potential benefit for children age 2 or older in specific high-risk groups.

Corresponding Author: To contact the corresponding author, Peter J. Gill, MD, DPhil, MSc, email peter.gill@sickkids.ca.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.4666)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

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Risk factors for severe disease among children hospitalized with RSV

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