Autism spectrum disorders are associated with difficulties in social communication, long attributed to individual socio-cognitive deficits. As a consequence of this perspective, stigma and pressure to conform to neurotypical social norms often lead to mental health challenges among autistic individuals. Emerging theories suggest that communication difficulties may rather arise from mismatches in perspectives between autistic and non-autistic partners. Addressing this mismatch collaboratively could transform the understanding of autism and improve communication outcomes.
Social behavior also varies significantly across cultures. Gestures, eye contact, and body language that are considered appropriate in one culture may be perceived differently in another. Nevertheless, current socio-cognitive assessments largely reflect Western norms, limiting their applicability to non-Western populations.
To bridge this gap, researchers from Japan conducted a cross-cultural analysis to compare mentalizing difficulties, or challenges in understanding the thoughts and feelings of others, in British and Japanese autistic and non-autistic adults. Led by Dr. Bianca Schuster, a researcher at Waseda University, Japan, with co-authors Associate Professor Yuko Okamoto and Professor Rieko Osu from Waseda University, Professor Hirotaka Kosaka from the University of Fukui, and Dr. Masakazu Ide from the National Rehabilitation Center for Persons With Disabilities, the study highlights the importance of considering neurodivergent perspectives rather than attributing difficulties solely to autistic individuals.
Explaining the rationale behind their work, Dr. Schuster says, “Autistic and non-autistic people have different experiences and therefore perceive and interact with the world differently. Such a mismatch in perspectives can lead to difficulties in understanding each other’s respective social cues – a problem termed the 'double empathy problem.’ This theory has received a lot of attention in recent years, but there are still very few studies that have formally tested it.” Their findings were published in Volume 16 of Molecular Autism on May 14, 2025.
The researchers used animations showing social scenes, depicted by moving triangles, and asked participants to interpret what was happening. They found that non-autistic British adults struggled to interpret animations created by their autistic peers. In contrast, British autistic adults demonstrated similar performances when interpreting animations made by both autistic and non-autistic people. The fact that British autistic adults did not perform better with animations made by their own neurotype may reflect that, in comparison to neurotypical groups, the perspectives of British neurodivergent individuals may be too varied.
Conversely, Japanese autistic and non-autistic adults interpreted animations created by their own and the respective other group with comparable accuracy. Notably, cross-cultural analyses revealed that while there was no difference in performance between Japanese and British non-autistic adults, Japanese autistic participants outperformed both groups of British participants. In addition, animations created by Japanese autistic adults were interpreted with higher accuracy by all autistic participants. Nevertheless, motor performance was comparable across all participants.
Overall, these findings support a paradigm shift toward treating autism as a different way of experiencing and interpreting the world, while recognizing it as a social disability shaped by challenges within a predominantly neurotypical environment. An inclusive environment that values socially diverse behaviors can support autistic individuals and enhance their mental well-being. Furthermore, the observed results do not likely mean that Japanese people are better at mentalizing than British individuals, because real-world difficulties in communication and social understanding do exist between autistic and non-autistic people in Japan, too. Instead, the findings may indicate that the task used in the current study may not be sensitive enough to detect mentalizing differences in the Japanese culture, highlighting the need to develop more culturally sensitive research and diagnostic tools.
“Cultural differences related to the diagnosis of autism may be subtle but can still lead to misclassification of cases and therefore have a significant impact on the lives of individuals. The results of this study highlight the urgent need for culturally inclusive research and the development of diagnostic criteria and tools that accurately reflect and respect the diverse manifestations of autism in different cultural contexts.” Dr. Schuster adds.
***
Reference
Authors: B. A. Schuster1,2,3, Y. Okamoto2,4, T. Takahashi1, Y. Kurihara1, C. T. Keating5,6, J. L. Cook5, H. Kosaka7, M. Ide8, H. Naruse7, C. Kraaijkamp5, and R. Osu1
DOI: 10.1186/s13229-025-00659-z
Affiliations: 1School of Human Sciences, Waseda University
2Waseda Institute for Advanced Study, Waseda University
3Department of Cognition, Emotion, and Methods in Psychology, University of Vienna of Vienna
4Department of Sports Science, Faculty of Health and Sports Science, Juntendo University
5Centre for Human Brain Health and School of Psychology, University of Birmingham
6Department of Experimental Psychology, University of Oxford
7University of Fukui
8National Rehabilitation Center for Persons With Disabilities
About Waseda University
Located in the heart of Tokyo, Waseda University is a leading private research university that has long been dedicated to academic excellence, innovative research, and civic engagement at both the local and global levels since 1882. The University has produced many changemakers in its history, including nine prime ministers and many leaders in business, science and technology, literature, sports, and film. Waseda has strong collaborations with overseas research institutions and is committed to advancing cutting-edge research and developing leaders who can contribute to the resolution of complex, global social issues. The University has set a target of achieving a zero-carbon campus by 2032, in line with the Sustainable Development Goals (SDGs) adopted by the United Nations in 2015.
To learn more about Waseda University, visit https://www.waseda.jp/top/en
About Dr. Bianca Schuster from Waseda University
Dr. Bianca Schuster is a researcher at Waseda University, Japan, and the University of Vienna, Austria. She is interested in the computational and neurochemical processes that shape our everyday social behavior. She conducts computational modeling to investigate how humans utilize uncertainties in their prior knowledge and new information to draw maximally optimal conclusions in social settings. Additionally, Dr. Schuster uses psychopharmacological approaches to better understand how certain neurotransmitters, like dopamine, modulate these social precision-weighting processes in healthy individuals and disorders such as Parkinson’s. She is also investigating how motor function and cultural differences affect social cognition.
END