PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Major progress in fertility preservation after treatment for cancer of the lymphatic system

2025-07-10
(Press-News.org)

Young patients with advanced Hodgkin’s lymphoma, a cancer of the lymphatic system, now have a better chance of having their own children after treatment. An international study led by the German Hodgkin Study Group (GHSG) at University Hospital Cologne and the University’s Faculty of Medicine has shown: The new BrECADD chemotherapy regimen preserves fertility significantly better than the previous standard eBEACOPP – without worsening the chances of recovery. The results were published under the title “Fertility in patients with advanced-stage classic Hodgkin lymphoma treated withBrECADD versus eBEACOPP: a secondary analysis of the multicentre, randomised, parallel, open-label, phase 3 HD21 Trial“ in the journal The Lancet Oncology.

In the HD21 trial, patients with advanced classical Hodgkin’s lymphoma received one of two therapies: either the experimental therapy with BrECADD or the previous standard of care eBEACOPP. Three years after treatment was concluded, there were major differences: In the BrECADD group, 95 per cent of women and 86 per cent of men had normal hormone levels again – compared to 73  per cent and 40 per cent respectively in the eBEACOPP group. More pregnancies and births were documented after the BrECADD regimen was applied. For men in particular, this means a significantly higher chance of biological paternity after treatment.

”BrECADD gives young adults with Hodgkin’s lymphoma a better chance of starting a family later in life – with an equally good or even slightly better cure rate,” explains Dr Justin Ferdinandus, Study Physician in the German Hodgkin Study Group (GHSG) and first author of the publication. “The HD21 study is fundamentally changing practice. Our data clearly show that BrECADD is the preferred first-line treatment for patients who wish to have children – at University Hospital Cologne and in the current Onkopedia guideline, this is already the new standard,” adds Dr Karolin Behringer, Study Physician at the GHSG and last author of the study.

The HD21 study is a randomized phase III clinical trial involving over 1,500 participants up to the age of 60 at 233 centres in nine countries. Among other things, the recovery of hormone levels (measured via blood serum levels of follicle-stimulating hormone) were examined along with pregnancies and births after therapy was concluded.

The study was supported by Takeda Oncology.

END



ELSE PRESS RELEASES FROM THIS DATE:

Fewer complications after additional ultrasound in pregnant women who feel less fetal movement

2025-07-10
It can be difficult to decide whether to expedite birth when a woman in the final stage of pregnancy perceives less fetal movements. An additional ultrasound measurement to assess resistance infetal blood vessels can help make this decision more accurately, leading to fewer complications during delivery. This is the conclusion of a large international study led by gynaecologist Sanne Gordijn from the University Medical Center Groningen (UMCG), in collaboration with Wessel Ganzevoort from Amsterdam UMC. Reduced Fetal Movement Can Be Concerning Sometimes, ...

Environmental impact of common pesticides seriously underestimated

2025-07-10
The environmental impact of nine pesticides, commonly used in grape cultivation, may have been significantly underestimated, suggesting current pesticide risk assessment criteria need updating. The research will be presented today [Friday 11 July] at the Goldschmidt Conference in Prague. In laboratory experiments, the nine pesticides that are used in viticulture and on other crops, far exceeded the two-day threshold set by the Stockholm Convention for the half-life of chemicals in the atmosphere. The researchers also identified several unknown molecules when they looked at how the pesticides break down and degrade in the atmosphere. Global use of pesticides has doubled since 1990, ...

The Milky Way could be teeming with more satellite galaxies than previously thought

2025-07-10
Embargoed until 00:01 BST on Friday 11 July 2025 (19.01 ET Thursday 10 July 2025) -With pictures- The Milky Way could have many more satellite galaxies than scientists have previously been able to predict or observe, according to new research. Cosmologists at Durham University, UK, used a new technique combining the highest-resolution supercomputer simulations that exist, alongside novel mathematical modelling, predicting the existence of missing “orphan” galaxies. Their findings suggest that there should be 80 or perhaps up to 100 more satellite galaxies surrounding ...

New study reveals surprising reproductive secrets of a cricket-hunting parasitoid fly

2025-07-10
A new study published in the Annals of the Entomological Society of America, offers the most detailed view to date of how this unusual fly develops and gives live birth—a rare phenomenon among flies. Led by undergraduate student Parker Henderson ‘22 of St. Olaf College, the study revealed remarkable insights into the reproductive biology of Ormia ochracea, a parasitic fly known for its ability to locate singing crickets using hyperacute directional hearing. Using a combination of dissection, fluorescence staining, and microscopy, the ...

Media Tip Sheet: Symposia at ESA2025

2025-07-10
The latest ecological research will be on full display at the Ecological Society of America’s upcoming Annual Meeting in Baltimore, Maryland, Aug. 10–15. A focal point of the conference, symposia consist of four 20-minute talks organized around a central theme of broad interest. These sessions consider topics from different angles, integrate multiple lines of evidence and offer new insights on ecological phenomena. This year, Annual Meeting symposia will address the questions and tools at the frontiers of ...

NSF CAREER Award will power UVA engineer’s research to improve drug purification

2025-07-10
Protein-based drugs are reshaping how we treat cancer and chronic illness, including diabetes, rheumatoid arthritis and multiple sclerosis. But behind each medicine is a complex manufacturing process, one that can be slowed down or derailed by microscopic contaminants. Chemical engineer Nick Vecchiarello at the University of Virginia’s School of Engineering and Applied Science wants to change that, and the National Science Foundation has taken notice. Vecchiarello, an assistant professor in the Department of Chemical Engineering, has earned an NSF CAREER ...

Tiny parasitoid flies show how early-life competition shapes adult success

2025-07-10
In a new study published and featured in the Annals of the Entomological Society of America, researchers have discovered that the developmental struggles of young parasitoid flies can have lasting effects that echo into adulthood. Led by a team from St. Olaf College in collaboration with others from the University of Strathclyde and the University of Toronto,  the study shows that when larvae of the acoustic parasitoid fly Ormia ochracea compete for resources inside a single cricket host, the consequences include reduced survival, smaller pupae, and ultimately smaller adult flies. These ...

New coating for glass promises energy-saving windows

2025-07-10
HOUSTON – (July 10, 2025) – A new coating for glass developed by Rice University researchers and collaborators could help reduce energy bills, especially during the cold season, by preventing heat-loss from leaky windows. The material ⎯ a transparent film made by weaving carbon into the atomic lattice of boron nitride ⎯ forms a thin, tough layer that reflects heat, resists scratches and shrugs off moisture, UV light and temperature swings. The researchers simulated how the material would behave in an actual-sized building in cities with cold winters like New York, Beijing and Calgary, showing it improved energy savings by 2.9% compared ...

Green spaces boost children’s cognitive skills and strengthen family well-being

2025-07-10
URBANA, Ill. – Access to nature promotes physical and mental health, and it is vital for children’s social and emotional development. Outdoor activities also influence family dynamics, helping to reduce stress and encourage connections. A new study from the University of Illinois Urbana-Champaign examines how green spaces and outdoor structures near the family residence interact with other factors in the household environment to influence executive functioning in early childhood. “We looked at what people have outside their ...

Ancient trees dying faster than expected in Eastern Oregon

2025-07-10
Eastern Oregon’s Malheur National Forest boasts some of the state’s oldest trees, including pine and larch that live more than 500 years. But many of those ancient trees are dying at an alarming rate, a new analysis shows. Between 2012 and 2023, a quarter of trees more than 300 years old in randomly located sites in roadless areas died, the study found. A triple whammy of drought, bug infestations and competition with younger trees is likely driving the decline. “It’s sad to see so many old trees dying,” said lead researcher ...

LAST 30 PRESS RELEASES:

Study unexpectedly finds living in rural, rather than urban environments in first five years of life could be a risk factor for developing type 1 diabetes

Editorial urges deeper focus on heart-lung interactions in pulmonary vascular disease

Five University of Tennessee faculty receive Fulbright Awards

5 advances to protect water sources, availability

OU Scholar awarded Fulbright for Soviet cinema research

Brain might become target of new type 1 diabetes treatments

‘Shore Wars:’ New research aims to resolve coastal conflict between oysters and mangroves, aiding restoration efforts

Why do symptoms linger in some people after an infection? A conversation on post-acute infection syndromes

Study reveals hidden drivers of asthma flare-ups in children

Physicists decode mysterious membrane behavior

New insights about brain receptor may pave way for next-gen mental health drugs

Melanoma ‘sat-nav’ discovery could help curb metastasis

When immune commanders misfire: new insights into rheumatoid arthritis inflammation

SFU researchers develop a new tool that brings blender-like lighting control to any photograph

Pups in tow, Yellowstone-area wolves trek long distances to stay near prey

AI breakthrough unlocks 'new' materials to replace lithium-ion batteries

Making molecules make sense: A regional explanation method reveals structure–property relationships

Partisan hostility, not just policy, drives U.S. protests

The Journal of Nuclear Medicine Ahead-of-Print Tip Sheet: August 1, 2025

Young human blood serum factors show potential to rejuvenate skin through bone marrow

Large language models reshape the future of task planning

Narrower coverage of MS drugs tied to higher relapse risk

Researchers harness AI-powered protein design to enhance T-cell based immunotherapies

Smartphone engagement during school hours among US youths

Online reviews of health care facilities

MS may begin far earlier than previously thought

New AI tool learns to read medical images with far less data

Announcing XPRIZE Healthspan as Tier 5 Sponsor of ARDD 2025

Announcing Immortal Dragons as Tier 4 Sponsor of ARDD 2025

Reporting guideline for chatbot health advice studies

[Press-News.org] Major progress in fertility preservation after treatment for cancer of the lymphatic system