PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Surgery for obstructive sleep apnea reduces daytime drowsiness

Surgery for obstructive sleep apnea reduces daytime drowsiness
2011-01-28
(Press-News.org) DETROIT – Patients with obstructive sleep apnea who undergo surgery to improve their breathing get a better night's sleep and therefore are less drowsy during the day, according to a new study from Henry Ford Hospital in Detroit.

The study finds surgery greatly reduces daytime sleepiness – a common side effect from this disorder in which the upper airway is partially or completely blocked during sleep – when compared to other non-surgical treatments for obstructive sleep apnea.

"This study validates what patients have told us regarding their improved alertness after surgery," says study author Kathleen L. Yaremchuk, M.D., Chair of the Department of Otolaryngology-Head and Neck Surgery at Henry Ford Hospital.

Results from the study will be presented Jan. 29 at the Triological Society's Combined Sections Meeting in Scottsdale, Ariz.

Obstructive sleep apnea syndrome (OSAS) affects an estimated 2 percent of women and 4 percent of men in the U.S., putting them at an increased risk for hypertension, coronary artery disease, congestive heart failure, stroke and death.

This sleep disorder occurs due to the collapse of the airway in the throat during sleep.

The blocked airway causes loud snoring and periodic pauses in breathing, sometimes hundreds of times a night. This can lead to excessive daytime sleepiness, and as a result decreased quality of life and an increased risk for injuries from motor vehicle accidents.

The treatment of choice for has been continuous positive airway pressure (CPAP) therapy during sleep, which uses a machine to increases air pressure in the throat to prevent the airway from collapsing. But it isn't the only treatment option.

Several surgical interventions are available to help patients with obstructive sleep apnea. Some surgical approaches work to open up the airway by removing excess tissue in the back of the throat, removing the tonsils or using radiofrequency waves to destroy tissue at the base of the tongue.

As part of their study, Dr. Yaremchuk and co-author Brandy Tacia, D.O., sought to determine if surgery may offer patients more relief from daytime sleepiness than CPAP.

The retrospective study looked at 40 patients who underwent one of three surgical interventions – uvulopalatopharyngoplasty, tonsillectomy or radiofrequency ablation of the base of tongue – between January 2007 and December 2009.

All patients in the study had at least mild obstructive sleep apnea, defined as five or more apnea/hypopnea events per hour of sleep and excessive daytime sleepiness. Many patients prior to surgery reported experiencing fatigue, snoring and failure to successfully use CPAP.

Both prior to and following surgery, patients were asked to complete the Epworth Sleepiness Score (ESS) questionnaire, which measures patients' general level of daytime sleepiness by rating their level of sleepiness (0 = never doze/sleep; 3 = high chance of dozing/sleeping) during eight common daytime activities such as watching TV, reading or driving. The ratings for each activity are then added together for a total Epworth Score.

Before surgery, all patients in the study reported having an ESS score of 10 or more, which is considered "very sleepy" during the day.

Following surgery, 38 patients' scores were significantly reduced, with a postoperative average score of 5.5. One patient in the study had no change in his score, while two experienced an increase.

Patients in the study also experienced a 50 percent reduction in apnea/hypopnea events during sleep following surgery.

"While this is not a prospective study, the results show an improvement in Epworth Sleepiness Score after surgery that is greater than typically reported with continuous positive airway pressure therapy," notes Dr. Tacia.



INFORMATION:

Along with Dr. Yaremchuk and Dr. Tacia, Henry Ford co-authors are Edward Peterson, Ph.D., and Thomas, Roth, Ph.D.

Funding: Henry Ford Hospital

[Attachments] See images for this press release:
Surgery for obstructive sleep apnea reduces daytime drowsiness

ELSE PRESS RELEASES FROM THIS DATE:

A mix of tiny gold and viral particles -- and the DNA ties that bind them

2011-01-28
Scientists have created a diamond-like lattice composed of gold nanoparticles and viral particles, woven together and held in place by strands of DNA. The structure – a distinctive mix of hard, metallic nanoparticles and organic viral pieces known as capsids, linked by the very stuff of life, DNA – marks a remarkable step in scientists' ability to combine an assortment of materials to create infinitesimal devices. The research, done by scientists at the University of Rochester Medical Center, Scripps Research Institute, and Massachusetts Institute of Technology, was published ...

Team looks to the cow rumen for better biofuels enzymes

Team looks to the cow rumen for better biofuels enzymes
2011-01-28
CHAMPAIGN, Ill. — When it comes to breaking down plant matter and converting it to energy, the cow has it all figured out. Its digestive system allows it to eat more than 150 pounds of plant matter every day. Now researchers report that they have found dozens of previously unknown microbial enzymes in the bovine rumen – the cow's primary grass-digestion chamber – that contribute to the breakdown of switchgrass, a renewable biofuel energy source. The study, in the journal Science, tackles a major barrier to the development of more affordable and environmentally sustainable ...

Study finds common ground for ecosystems and fishing in Northwest Mexico

Study finds common ground for ecosystems and fishing in Northwest Mexico
2011-01-28
Researchers at Scripps Institution of Oceanography at UC San Diego have completed a new study on the geography of commercial fisheries in Northwest Mexico and the results could have far-ranging implications for the sustainable future of marine wildlife in the area. The scientists, led by Scripps postdoctoral researcher Brad Erisman, analyzed data from local fisheries offices around the region that includes Baja California as well as Gulf of California coasts from Sonora south to Nayarit. The region accounts for more than 60 percent of fishing production in Mexico. The ...

Test shows dinosaurs survived mass extinction by 700,000 years

2011-01-28
University of Alberta researchers determined that a fossilized dinosaur bone found in New Mexico confounds the long established paradigm that the age of dinosaurs ended between 65.5 and 66 million years ago. The U of A team, led by Larry Heaman from the Department of Earth and Atmospheric Sciences, determined the femur bone of a hadrosaur as being only 64.8 million years old. That means this particular plant eater was alive about 700,000 years after the mass extinction event many paleontologists believe wiped all non-avian dinosaurs off the face of earth, forever. Heaman ...

Researchers identify biomarkers of poor outcomes in preemies

2011-01-28
Researchers at Cincinnati Children's Hospital Medical Center have identified biomarkers of poor outcomes in preterm infants that may help identify new approaches to prevention. Ardythe Morrow, PhD, a researcher at the Cincinnati Children's Perinatal Institute, has identified a polymorphism – a variant in a particular DNA sequence – in a gene important to the development of the immune system. She found that this polymorphism raises the risk of bad outcomes in preterm infants, including death; necrotizing enterocolitis, which is the death of intestinal tissue; and gram ...

Memory training explored as strategy for addiction treatment

Memory training explored as strategy for addiction treatment
2011-01-28
People with addictions to stimulants tend to choose instant gratification or a smaller but sooner reward over a future benefit, even if the future reward is greater. Reduced value of a future reward, called "delay discounting" by neuroscientists, is the major challenge for treatment of addiction. A new study in the February 2011 (Vol. 69, Issue 3) Biological Psychiatry appears to present a strategy for increasing the value of future rewards in the minds of addicts. "The hope is for a new intervention to help addicts," said Warren K. Bickel, professor and director of ...

Bacteria possible cause of preterm births

2011-01-28
The type of bacteria that colonize the placenta during pregnancy could be associated with preterm birth and other developmental problems in newborns according to research published in the current issue of the online journal mBio®. "The fetal inflammatory response appears to contribute to the onset of preterm labor, fetal injury and complications, underlying lifetime health challenges facing these children," say the researchers from Harvard Medical School, Brigham and Women's Hospital and Children's Hospital of Boston. "Our data suggest that placental colonization by specific ...

Unemployment among doctoral scientists and engineers lower than among the general population in 2008

2011-01-28
Data released today by the National Science Foundation show the recent economic recession had less effect on doctoral degree holders in science, engineering and health (SEH) fields than it did on the general population. According to a new NSF report, the unemployment rate in October 2008 for SEH doctorate recipients was 1.7 percent, whereas the unemployment rate for the total U.S. labor force was 6.6 percent. The report, "Unemployment Among Doctoral Scientists and Engineers Remained Below the National Average in 2008," was issued by NSF's Division of Science Resources ...

Stem cells show promise in repairing a child's heart

2011-01-28
Visionaries in the field of cardiac therapeutics have long looked to the future when a damaged heart could be rebuilt or repaired by using one's own heart cells. A study published in the February issue of Circulation, a scientific journal of the American Heart Association, shows that heart stem cells from children with congenital heart disease were able to rebuild the damaged heart in the laboratory. Sunjay Kaushal, MD, PhD, surgeon in the Division of Cardiovascular Thoracic Surgery at Children's Memorial Hospital and assistant professor of surgery at Northwestern ...

New research shows infants understand social dominance

2011-01-28
VIDEO: Assistant professor Lotte Thomsen, from the Department of Psychology at the University of Copenhagen, has published a paper showing that infants less than one year old understand social dominance and... Click here for more information. New research from the University of Copenhagen and Harvard University has found that infants less than one year old understand social dominance and use relative size to predict who will prevail when two individuals' goals conflict. The ...

LAST 30 PRESS RELEASES:

Breakthrough idea for CCU technology commercialization from 'carbon cycle of the earth'

Keck Hospital of USC earns an ‘A’ Hospital Safety Grade from The Leapfrog Group

Depression research pioneer Dr. Philip Gold maps disease's full-body impact

Rapid growth of global wildland-urban interface associated with wildfire risk, study shows

Generation of rat offspring from ovarian oocytes by Cross-species transplantation

Duke-NUS scientists develop novel plug-and-play test to evaluate T cell immunotherapy effectiveness

Compound metalens achieves distortion-free imaging with wide field of view

Age on the molecular level: showing changes through proteins

Label distribution similarity-based noise correction for crowdsourcing

The Lancet: Without immediate action nearly 260 million people in the USA predicted to have overweight or obesity by 2050

Diabetes medication may be effective in helping people drink less alcohol

US over 40s could live extra 5 years if they were all as active as top 25% of population

Limit hospital emissions by using short AI prompts - study

UT Health San Antonio ranks at the top 5% globally among universities for clinical medicine research

Fayetteville police positive about partnership with social workers

Optical biosensor rapidly detects monkeypox virus

New drug targets for Alzheimer’s identified from cerebrospinal fluid

Neuro-oncology experts reveal how to use AI to improve brain cancer diagnosis, monitoring, treatment

Argonne to explore novel ways to fight cancer and transform vaccine discovery with over $21 million from ARPA-H

Firefighters exposed to chemicals linked with breast cancer

Addressing the rural mental health crisis via telehealth

Standardized autism screening during pediatric well visits identified more, younger children with high likelihood for autism diagnosis

Researchers shed light on skin tone bias in breast cancer imaging

Study finds humidity diminishes daytime cooling gains in urban green spaces

Tennessee RiverLine secures $500,000 Appalachian Regional Commission Grant for river experience planning and design standards

AI tool ‘sees’ cancer gene signatures in biopsy images

Answer ALS releases world's largest ALS patient-based iPSC and bio data repository

2024 Joseph A. Johnson Award Goes to Johns Hopkins University Assistant Professor Danielle Speller

Slow editing of protein blueprints leads to cell death

Industrial air pollution triggers ice formation in clouds, reducing cloud cover and boosting snowfall

[Press-News.org] Surgery for obstructive sleep apnea reduces daytime drowsiness