Donor diabetes and 1-year Descemet membrane endothelial keratoplasty success rate

JAMA Ophthalmology

2025-10-17

(Press-News.org) About The Study: The 1-year success rate in eyes undergoing Descemet membrane endothelial keratoplasty (DMEK) with successfully prepared tissue was very high regardless of donor diabetes status. These results, supported by the separately reported finding that endothelial cell loss and cornea morphometry after 1 year were not affected by donor diabetes status, provide strong support for having no restrictions on the use of tissue from donors with diabetes for DMEK.

Corresponding Author: To contact the corresponding author, Jonathan H. Lass, MD, email deks@case.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaophthalmol.2025.4253)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being presented at the Cornea and Eye Banking Forum and the American Academy of Ophthalmology’s annual meeting.

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