Earlier studies in which Prof. Haim has participated at the University of Haifa, have shown that people living in areas that have more night-time illumination are more susceptible to prostate cancer in men and breast cancer in women. The researchers' hypothesis was that LAN harms production of melatonin, a hormone that is released from the pineal gland during the dark part of the 24h cycle and which is linked to the body's cyclical night-day activity and seasonality. When this hormone is suppressed, the occurrence of cancer rises.
The current study, in which Dr. Fuad Fares and Adina Yokler, Orna Harel and Hagit Schwimmer also participated, set out to establish or refute this hypothesis. In order to do so, four groups of lab mice injected with cancerous cells were examined: one group was exposed to "long days" of 16 hours of light and 8 hours of darkness, simulating exposure to artificial light beyond the natural number of light hours in a day; a second group was exposed to the same "long days" but were treated with melatonin; a third group was exposed to "short days" of 8 light hours and 16 dark hours; and a fourth group was exposed to the same "short days" but during the dark hours was exposed to a half-hour interval of light.
The results show once again the clear link between LAN and cancer: the cancerous growths in mice exposed to "short days" were smallest (0.85 cubic cm. average), while those mice exposed to the interval of LAN during dark hours had larger growths (1.84 cubic cm. average) and those exposed to "long days" even larger growths (5.92 cubic cm. average).
The study also discovered that suppression of melatonin definitely influences development of the tumor. The size of tumor in mice exposed to "long days" but treated with melatonin was only 0.62 cubic cm. on average, which is not much different from the size of the growth in mice exposed to "short days". The study also found that the death rate in mice treated with melatonin was significantly lower than in those not treated.
The researchers say that their study results show that suppression of melatonin due to exposure to LAN is linked to the worrying rise in the number of cancer patients over the past few years. However, it is not yet clear what mechanism causes this.
"Exposure to LAN– disrupts our biological clock and affects the cyclical rhythm that has developed over hundreds of millions of evolutionary years that were devoid of LAN. Light pollution as an environmental problem is gaining awareness around the world, and the World Health Organization's International Agency for Research on Cancer (IARC) has already classified working the night shift as a higher grade of cancer risk," the researchers noted.
INFORMATION:
For more details contact Rachel Feldman • Tel: +972-4-8288722
Communications and Media Relations
University of Haifa
press@univ.haifa.ac.il
Connection between light at night and cancer revealed in additional study
New study from the Center for Interdisciplinary Chronobiological Research at the University of Haifa has found an additional link between light at night and cancer
2010-09-04
(Press-News.org) A new study from the Center for Interdisciplinary Chronobiological Research at the University of Haifa has found an additional link between Light At Night (LAN) and cancer. This research joins a series of earlier studies carried out at the University of Haifa that also established the correlation. "High power light bulbs contribute more to 'environmental light pollution', which the study has shown is a carcinogenic pollution," notes Prof. Abraham Haim, who headed the study.
ELSE PRESS RELEASES FROM THIS DATE:
Listening to ancient colors
2010-09-04
A team of McGill chemists have discovered that a technique known as photoacoustic infrared spectroscopy could be used to identify the composition of pigments used in art work that is decades or even centuries old. Pigments give artist's materials colour, and they emit sounds when light is shone on them.
"The chemical composition of pigments is important to know, because it enables museums and restorers to know how the paints will react to sunlight and temperature changes," explained Dr. Ian Butler, lead researcher and professor at McGill's Department of Chemistry. Without ...
EMAS publishes position statements about the post-reproductive health of women
2010-09-04
Amsterdam, 2 September, 2010 - Elsevier announced today the publication of four important position statements from the European Menopause and Andropause Society (EMAS) in the journal Maturitas (http://www.maturitas.org/) on common management problems in the post-reproductive health of women. The statements cover the management of the menopause in the context of obesity, epilepsy, endometriosis and premature ovarian failure. Each statement has summary recommendations as a quick aid for the busy clinician.
"The expanding ageing female population means that clinicians ...
New climate change mitigation schemes could benefit elites rather than the rural poor
2010-09-04
Oaxaca, Mexico (3 September 2010)—With governments across Latin America preparing to implement a new financial mechanism aimed at mitigating climate change by curbing carbon emissions from the destruction of tropical forests, experts gathering here today warned against a "one-size-fits-all" approach, calling instead for flexible, balanced solutions to the thorny dilemmas surrounding this new mechanism. Among the experts' chief worries is that the wealthy and powerful could capture many of the benefits, largely at the expense of rural communities, including indigenous groups. ...
Safety cultures in EMS agencies vary widely, Pitt study finds
2010-09-04
PITTSBURGH, Sept. 2 – A survey of emergency medical services (EMS) agencies from across the country found wide variation in perceptions of workplace safety culture—providing a tool that might point to potential patient safety threats, according to researchers at the University of Pittsburgh School of Medicine.
The study, to be published in the October/December issue of Prehospital Emergency Care and now available online, analyzed survey results from 61 EMS agencies in the U.S. and Canada. Researchers adapted a survey used in other health care settings to measure paramedic ...
Biomedical research policy needed for therapies, economic growth, education and security
2010-09-04
Washington, DC -- Bold and coordinated leadership at the federal level is essential to create secure, long-term, sustainable biomedical research funding policies based on strategic priorities, say the authors of a commentary about America's fledgling biomedical research framework published in this week's The Journal of the American Medical Association.
In "A New Research and Development Policy Framework for the Biomedical Research Enterprise," by Howard J. Federoff, MD, PhD, of Georgetown University Medical Center and Elaine R. Rubin, PhD, of Association of Academic Health ...
Hormel Institute study reveals capsaicin can act as cocarcinogen
2010-09-04
The September cover story of the nation's leading cancer journal, "Cancer Research," features a new study from The Hormel Institute, University of Minnesota, that links capsaicin, a component of chili peppers, to skin cancer. While the molecular mechanisms of the cancer-promoting effects of capsaicin are not clear and remain controversial, The Hormel Institute has shown a definite connection to formation of skin cancer through various laboratory studies.
Ann Bode, professor in the institute's Cellular and Molecular Biology Research Section, led the research team on this ...
You say, 'bio-math,' I say, 'math-bio': Crossing science education divide
2010-09-04
BETHESDA, MD, SEPT 2, 2010⎯The old joke is a joke no more. In a special September issue of the ASCB's online journal, CBE—Life Sciences Education (CBE-LSE), the adage that biology is for science students who don't do math is laid to rest forever. "Bio-math" or "math-bio" is in the future for students of both disciplines, say the contributors of seven essays and 17 research articles on new ways to integrate mathematical thinking into biology education and introduce biological problems into math learning.
"The national scientific and academic community has issued ...
K-State research project offers insight into superstitious behavior
2010-09-04
MANHATTAN, KAN. -- People who believe that fate and chance control their lives are more likely to be superstitious -- but when faced with death they are likely to abandon superstition altogether, according to a recent Kansas State University undergraduate research project.
The project, led by Scott Fluke, a May 2010 K-State bachelor's graduate in psychology, Olathe, focuses on personality traits that lead to superstition. Fluke received a $500 Doreen Shanteau Undergraduate Research Fellowship in 2009 to work with the team of Russell Webster, graduate student in psychology, ...
Edible nanostructures
2010-09-04
Sugar, salt, alcohol and a little serendipity led a Northwestern University research team to discover a new class of nanostructures that could be used for gas storage and food and medical technologies. And the compounds are edible.
The porous crystals are the first known all-natural metal-organic frameworks (MOFs) that are simple to make. Most other MOFs are made from petroleum-based ingredients, but the Northwestern MOFs you can pop into your mouth and eat, and the researchers have.
"They taste kind of bitter, like a Saltine cracker, starchy and bland," said Ronald ...
Low grades in adolescence linked to dopamine genes
2010-09-04
The academic performance of adolescents will suffer in at least one of four key subjects –– English, math, science, history –– if their DNA contains one or more of three specific dopamine gene variations, according to a study led by renowned biosocial criminologist Kevin M. Beaver of The Florida State University.
The research sheds new light on the genetic components of academic performance during middle and high school, and on the interplay of specific genes and environmental factors such as peer behavior or school conditions.
"We believe that dopaminergic genes ...
LAST 30 PRESS RELEASES:
Osteoporosis treatment benefits people older than 80
Consuming more protein may protect patients taking anti-obesity drug from muscle loss
Thyroid treatment may improve gut health in people with hypothyroidism
Combination of obesity medication tirzepatide and menopause hormone therapy fuels weight loss
High blood sugar may have a negative impact on men’s sexual health
Emotional health of parents tied to well-being of children with growth hormone deficiency
Oxytocin may reduce mood changes in women with disrupted sleep
Mouse study finds tirzepatide slowed obesity-associated breast cancer growth
CMD-OPT model enables the discovery of a potent and selective RIPK2 inhibitor as preclinical candidate for the treatment of acute liver injury
Melatonin receptor 1a alleviates sleep fragmentation-aggravated testicular injury in T2DM by suppression of TAB1/TAK1 complex through FGFR1
Single-cell RNA sequencing reveals Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131–TNF signaling pathway-mediated differentiation of immunosuppressive dendritic ce
Acta Pharmaceutica Sinica B Volume 15, Issue 7 Publishes
New research expands laser technology
Targeted radiation offers promise in patients with metastasized small cell lung cancer to the brain
A high clinically translatable strategy to anti-aging using hyaluronic acid and silk fibroin co-crosslinked hydrogels as dermal regenerative fillers
Mount Sinai researchers uncover differences in how males and females change their mind when reflecting on past mistakes
CTE and normal aging are difficult to distinguish, new study finds
Molecular arms race: How the genome defends itself against internal enemies
Tiny chip speeds up antibody mapping for faster vaccine design
KTU experts reveal why cultural heritage is important for community unity
More misfolded proteins than previously known may contribute to Alzheimer’s and dementia
“Too much going on”: Autistic adults overwhelmed by non-verbal social cues
What’s driving America’s deep freezes in a warming world?
A key role of brain protein in learning and memory is deciphered by scientists
Heart attacks don’t follow a Hollywood script
Erin M. Schuman wins 2026 Nakasone Award for discovery on neural synapse function and change during formation of memories
Global ocean analysis could replace costly in-situ sound speed profiles in seafloor positioning, study finds
Power in numbers: Small group professional coaching reduces rates of physician burnout by nearly 30%
Carbon capture, utilization, and storage: A comprehensive review of CCUS-EOR
New high-temperature stable dispersed particle gel for enhanced profile control in CCUS applications
[Press-News.org] Connection between light at night and cancer revealed in additional studyNew study from the Center for Interdisciplinary Chronobiological Research at the University of Haifa has found an additional link between light at night and cancer