PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Mom or dad has bipolar disorder? Keep stress in check

Concordia study finds children of bipolar parents overly sensitive to stress

2011-05-08
(Press-News.org) This release is available in French. Montreal May 5, 2011 – Children whose mother or father is affected by bipolar disorder may need to keep their stress levels in check. A new international study, led by Concordia University, suggests the stress hormone cortisol is a key player in the mood disorder. The findings published in Psychological Medicine, are the first to show that cortisol is elevated more readily in these children in response to the stressors of normal everyday life.

"Previous research has shown that children of parents with bipolar disorder are four times as likely to develop mood disorders as those from parents without the condition," says senior author Mark Ellenbogen, Canada Research Chair in Developmental Psychopathology at Concordia University and a member of the Centre for Research in Human Development. "The goal of our study was to determine how this is happening."

Cortisol, the telltale hormone

Ellenbogen and colleagues had previously shown that cortisol levels in children with a parent affected by bipolar disorder were higher than kids whose parents were unaffected by the condition. The current study measured cortisol levels in these same individuals, now in late adolescence and early adulthood, as well as chronic and episodic stress. When exposed to either type of stress, children of parents with bipolar disorder showed a greater increase in cortisol than those of parents without the disorder. "Our study demonstrates that affected children are biologically more sensitive to the experience of stress in their natural and normal environment compared to their peers," says Ellenbogen. "This higher reactivity to stress might be one explanation of why these offspring end up developing disorders and is a clear risk factor to becoming ill later on."

"We think we might be beginning to understand where we can intervene to actually prevent this increased sensitivity from developing," continues Ellenbogen. "We believe this sensitivity develops during childhood and our suspicion is that if you could teach both parents and their offspring on how to cope with stress, how to deal with problems before they turn into larger significant stressors and difficulties, this would have a profound impact."

###

About cortisol:
Cortisol is a hormone that is produced by the body in response to anxiety and researchers use cortisol to challenge the biological response to stress.

About bipolar disorder:
Bipolar disorder, which is also known as manic depression, is a treatable illness marked by extreme changes in mood, thought, energy and behavior. Bipolar disorder is also known as manic depression because a person's mood can alternate between mania (highs) and depression (lows). These changes in mood, or "mood swings," can last for hours, days, weeks or months.

Partners in research:
This work was supported by the Canadian Institutes of Health Research, the Social Sciences and Humanities Research Council of Canada and the Fonds du Québec en Recherche sur la Société de la Culture.

About the study:
The paper, "Sensitivity to stress among the offspring of parents with bipolar disorder: a study of daytime cortisol levels," was co-authored by C. S. Ostiguy, M. A. Ellenbogen of Concordia University; C.-D. Walker of the Douglas Hospital Research Centre and McGill University; E. F. Walker of Emory University; S. Hodgins of King's College London, Heidelberg University and the Université de Montréal.

Related links: Cited study: http://journals.cambridge.org/action/displayJournal?jid=PSM Concordia Department of Psychology: www-psychology.concordia.ca Centre for Research in Human Development: http://crdh.concordia.ca

Media contact:
Sylvain-Jacques Desjardins
Senior advisor, external communications
Concordia University
Phone: 514-848-2424, ext. 5068
Email: s-j.desjardins@concordia.ca
Twitter: http://twitter.com/concordianews
Concordia news: http://now.concordia.ca

END



ELSE PRESS RELEASES FROM THIS DATE:

Artful dodgers: Responding but not answering often undetected

2011-05-08
WASHINGTON -- How can some people respond to a question without answering the question, yet satisfy their listeners? This skill of "artful dodging" and how to better detect it are explored in an article published by the American Psychological Association. People typically judge a speaker with the goal of forming an opinion of the speaker, which can make them susceptible to dodges, according to the study published online in the Journal of Experimental Psychology: Applied. Limited attention capacity is another reason people fall for dodges, said the authors, citing a previous ...

Surgery reduces risk of mortality due to prostate cancer even for low-risk groups

2011-05-08
A Swedish research team partly consisting of researchers from Uppsala University followed a group of prostate cancer patients in the Nordic region for 15 years. The study found, among other things, that surgery reduces the risk that men with prostate cancer (even those with low-risk tumours) will die within 15 years. The results were published today in the New England Journal of Medicine. The researchers followed Swedish, Finnish and Icelandic prostate cancer patients. Radical prostatectomy (surgical removal of the prostate gland) was performed on 347 randomly chosen ...

Quantum simulation with light: Frustrations between photon pairs

Quantum simulation with light: Frustrations between photon pairs
2011-05-08
Researchers from the Vienna Center for Quantum Science and Technology at the University of Vienna and the Institute of Quantum Optics and Quantum Information at the Austrian Academy of Sciences used a quantum mechanical system in the laboratory to simulate complex many-body systems. This experiment, which is published in Nature Physics, promises future quantum simulators enormous potential insights into unknown quantum phenomena. Already the behavior of relatively small quantum systems cannot be calculated because quantum states contain much more information than their ...

Normal stem cells made to look and act like cancer stem cells

Normal stem cells made to look and act like cancer stem cells
2011-05-08
CHAPEL HILL, N.C. – Researchers at the University of North Carolina at Chapel Hill School of Medicine, after isolating normal stem cells that form the developing placenta, have given them the same properties of stem cells associated with an aggressive type of breast cancer. The scientific first opens the door for developing novel targeted therapies aimed at triple negative breast cancer. Known also as TNBC, this is a highly recurrent tumor that spreads aggressively beyond its original site in the breast and carries a poor prognosis for patients who have it. The study ...

Scientists sequence genomes of 2 major threats to American food and fuel

2011-05-08
An international team of researchers co-led by a University of Minnesota scientist has sequenced the genomes of two fungal pathogens -- one that threatens global wheat supplies and another that limits production of a tree crop valued as a future source for biofuel. The sequencing of the genetic codes of wheat stem rust pathogen (Puccinia graminis) and poplar leaf rust pathogen (Melampsora larici-populina) is expected to help researchers develop control strategies to address worldwide threats to wheat fields and tree plantations. The study, which was published this week ...

Who knows you best? Not you, say psychologists

2011-05-08
Know thyself. That was Socrates' advice, and it squares with conventional wisdom. "It's a natural tendency to think we know ourselves better than others do," says Washington University in St. Louis assistant professor Simine Vazire. But a new article by Vazire and her colleague Erika N. Carlson reviews the research and suggests an addendum to the philosopher's edict: Ask a friend. "There are aspects of personality that others know about us that we don't know ourselves, and vice-versa," says Vazire. "To get a complete picture of a personality, you need both perspectives." ...

Seed mixtures and insurance pest management: Future norm in the Corn Belt?

2011-05-08
As the use of biotechnology increases and more companies move forward with the U.S. Environmental Protection Agency's approval to begin full-scale commercialization of seed mixtures in transgenic insecticidal corn, many researchers believe pest monitoring will become even more difficult. "Seed mixtures may make insect resistance management (IRM) risky because of larval behavior and greater adoption of insecticidal corn," said David Onstad, professor in the Department of Crop Sciences at the University of Illinois and lead author in a recent article published in the Journal ...

Scientists afflict computers with schizophrenia to better understand the human brain

2011-05-08
AUSTIN, Texas—Computer networks that can't forget fast enough can show symptoms of a kind of virtual schizophrenia, giving researchers further clues to the inner workings of schizophrenic brains, researchers at The University of Texas at Austin and Yale University have found. The researchers used a virtual computer model, or "neural network," to simulate the excessive release of dopamine in the brain. They found that the network recalled memories in a distinctly schizophrenic-like fashion. Their results were published in April in Biological Psychiatry. "The hypothesis ...

More than 20 percent of atheist scientists are spiritual

2011-05-08
More than 20 percent of atheist scientists are spiritual, according to new research from Rice University. Though the general public marries spirituality and religion, the study found that spirituality is a separate idea – one that more closely aligns with scientific discovery – for "spiritual atheist" scientists. The research will be published in the June issue of Sociology of Religion. Through in-depth interviews with 275 natural and social scientists at elite universities, the Rice researchers found that 72 of the scientists said they have a spirituality that is ...

Einstein researchers find key gene in childhood cancer

2011-05-08
May 5, 2011 – (BRONX, NY) – There are no effective treatments for rhabdoid tumors – aggressive childhood cancers that usually strike children under three years old and affect the brain or kidneys. The disease is extremely rare – fewer than 10 cases are diagnosed each year in the U.S. – but is particularly difficult to treat and almost always fatal. Now scientists at Albert Einstein College of Medicine of Yeshiva University have identified a target for potential therapies for these tumors: a gene called Aurora A that is vital for tumor growth. The research team was led ...

LAST 30 PRESS RELEASES:

Twelve questions to ask your doctor for better brain health in the new year

Microelectronics Science Research Centers to lead charge on next-generation designs and prototypes

Study identifies genetic cause for yellow nail syndrome

New drug to prevent migraine may start working right away

Good news for people with MS: COVID-19 infection not tied to worsening symptoms

Department of Energy announces $179 million for Microelectronics Science Research Centers

Human-related activities continue to threaten global climate and productivity

Public shows greater acceptance of RSV vaccine as vaccine hesitancy appears to have plateaued

Unraveling the power and influence of language

Gene editing tool reduces Alzheimer’s plaque precursor in mice

TNF inhibitors prevent complications in kids with Crohn's disease, recommended as first-line therapies

Twisted Edison: Bright, elliptically polarized incandescent light

Structural cell protein also directly regulates gene transcription

Breaking boundaries: Researchers isolate quantum coherence in classical light systems

Brain map clarifies neuronal connectivity behind motor function

Researchers find compromised indoor air in homes following Marshall Fire

Months after Colorado's Marshall Fire, residents of surviving homes reported health symptoms, poor air quality

Identification of chemical constituents and blood-absorbed components of Shenqi Fuzheng extract based on UPLC-triple-TOF/MS technology

'Glass fences' hinder Japanese female faculty in international research, study finds

Vector winds forecast by numerical weather prediction models still in need of optimization

New research identifies key cellular mechanism driving Alzheimer’s disease

Trends in buprenorphine dispensing among adolescents and young adults in the US

Emergency department physicians vary widely in their likelihood of hospitalizing a patient, even within the same facility

Firearm and motor vehicle pediatric deaths— intersections of age, sex, race, and ethnicity

Association of state cannabis legalization with cannabis use disorder and cannabis poisoning

Gestational hypertension, preeclampsia, and eclampsia and future neurological disorders

Adoption of “hospital-at-home” programs remains concentrated among larger, urban, not-for-profit and academic hospitals

Unlocking the mysteries of the human gut

High-quality nanodiamonds for bioimaging and quantum sensing applications

New clinical practice guideline on the process for diagnosing Alzheimer’s disease or a related form of cognitive impairment or dementia

[Press-News.org] Mom or dad has bipolar disorder? Keep stress in check
Concordia study finds children of bipolar parents overly sensitive to stress