PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Gene study sheds new light on origins of British men

2011-08-25
(Press-News.org) New genetic evidence reveals that most British men are not descended from immigrant farmers who migrated east 5,000-10,000 years ago – contrary to previous research.

Instead, scientists from the Universities of Oxford and Edinburgh say that most European men can trace their lineage to people – most likely hunter-gatherers – who had settled in Europe long before that time.

The latest study, based on the most common genetic lineage in European males, aims to correct an analysis of genetic data, published last year. It had reported that most British men came from people who migrated west, with the spread of agriculture, from the Near East.

More than 100 million European men have a set of genes called R-M269, including about three-quarters of British men. A key question in understanding the peopling of Europe is when this group spread out across Europe.

Researchers say their work shows that the set of genes chosen to estimate the age of this group of men vary the outcome enormously. They add that the previously reported east-west pattern is not found in their larger and more comprehensive dataset. This, the Oxford – Edinburgh team says, leaves little evidence for a farmer-led dispersal of this major group.

According to Dr Cristian Capelli, the Oxford geneticist who led the research, the study "resets" the debate on the peopling of Europe. He says, "Our works overturns the recent claims of European Y chromosomes being brought into the continent by farmers."

Co-author, Dr Jim Wilson of the University of Edinburgh's Centre for Population Health Sciences, adds that the paper shows for the first time that certain properties of the genes studied strongly influence the accuracy of the date estimate.

"Estimating a date at which an ancestral lineage originated is an interesting application of genetics, but unfortunately it is beset with difficulties and it is very difficult to provide good dates. Many people assume that the more genes the more accurate the dates, but this is not the case: some genetic markers are more suited to dating than others."

The study also reports multiple subgroups of the R-M269 group that are very common in different parts of Europe, consistent with expansion of these different groups in each place.

### The peopling of Europe and the cautionary tale of Y chromosome lineage R-M269 is published online in the Proceedings of the Royal Society.

For more information please contact Eleanor Cowie, Press and PR Office, on Tel: 0131 650 6514 or Eleanor.Cowie@ed.ac.uk


ELSE PRESS RELEASES FROM THIS DATE:

Feeding the five thousand -- or was it three?

2011-08-25
The public should view crowd estimation with scepticism, say the authors of a study published today in Significance, the magazine of the Royal Statistical Society and the American Statistical Association, as they suggest more reliable alternatives to current estimating methods. Estimates of crowd sizes vary greatly, and the success of an event is often measured by the size of the crowd. Organisers of the 2007 "Stop the War" demonstration in London reported crowds of 60,000, whereas the police reported just 10,000. The US Government's estimate of the crowds at Obama's ...

Three-quarters of those who have lost jobs and health insurance are skipping needed health care

2011-08-25
New York, NY, August 24, 2011— Nearly three-quarters (72%) of people who lost their health insurance when they lost their jobs over the last two years said that they skipped needed health care or did not fill prescriptions because of cost, according to a new Commonwealth Fund report. The same proportion is also struggling with medical bills or medical debt, compared to about half (49%) who lost jobs but not their health insurance. Six in 10 working Americans rely on health insurance obtained through their employer, and when an estimated 15 million working-age adults ...

Atlanta Bankruptcy Law Firm Clark & Washington Offers Twelve Convenient Locations

2011-08-25
The Atlanta bankruptcy lawyers at Clark & Washington invite the residents of the Atlanta area to visit the firm at any of their twelve locations within the vicinity. As Georgia's largest bankruptcy filer, Clark & Washington offers legal assistance to individuals experience financial difficulties throughout the metro Atlanta area at the location most convenient for the client. The Atlanta bankruptcy attorneys at Clark & Washington maintain law offices within the metro Atlanta area at each of the following twelve locations: Chamblee-Tucker 3300 Northeast ...

Scientists identify point of entry for deadly Ebola virus

2011-08-25
FINDINGS: Where all of us inherit one copy of each chromosome from each of our two parents, cell lines exist with only a single set, and thus with a single copy of each individual gene, instead of the usual two. Using an unusual human cell line of this type, Whitehead Institute researchers and their collaborators performed a genetic screen and identified a protein used by Ebola virus to gain entry into cells and begin replicating. The discovery may offer a new approach for the development of antiviral therapeutics. RELEVANCE: Ebola virus, the cause of Ebola hemorrhagic ...

Researchers produce detailed map of gene activity in mouse brain

2011-08-25
A new atlas of gene expression in the mouse brain provides insight into how genes work in the outer part of the brain called the cerebral cortex. In humans, the cerebral cortex is the largest part of the brain, and the region responsible for memory, sensory perception and language. Mice and people share 90 percent of their genes so the atlas, which is based on the study of normal mice, lays a foundation for future studies of mouse models for human diseases and, eventually, the development of treatments. Researchers from the National Human Genome Research Institute (NHGRI), ...

Lawrenceville Doctors Office in Gwinnett County Offers Back to School Health Checks for Students

2011-08-25
Rodriguez MD, a leading Lawrenceville clinic and bilingual Lawrenceville family practice in Gwinnett County, GA, is currently offering Back to School Health Checks and sports physicals for preschool through college age students. Available beginning in August 2011, the medical practice will accept patients by appointment and walk-in for Health Checks. Patients will be able to learn about their physical condition and treatment if a problem is identified. Available services at Rodriguez MD's Gwinnett family clinic include: - Physicals - Lab Tests - Blood Pressure - ...

Exercise can substitute effectively as second 'medication' for people with depression

2011-08-25
DALLAS – Aug. 24, 2011 – Exercise can be as effective as a second medication for as many as half of depressed patients whose condition have not been cured by a single antidepressant medication. UT Southwestern Medical Center scientists involved in the investigation, recently published in the Journal of Clinical Psychiatry, found that both moderate and intense levels of daily exercise can work as well as administering a second antidepressant drug, which is often used when initial medications don't move patients to remission. The type of exercise needed, however, depends ...

Cluster headache -- it's nice when it stops

2011-08-25
Cluster headache has a substantial detrimental effect on quality of life. New invasive procedures, such as hypothalamic deep brain stimulation and bilateral occipital nerve stimulation, may help patients with chronic refractory headache. This is one of the conclusions reached by Charly Gaul and co-authors from the Department of Neurology at the University Medical Center Essen in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2011; 108(33): 543-9). Cluster headache is the commonest trigemino-autonomic headache, affecting some 120,000 people in ...

A question of gene silencing

2011-08-25
When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do they promote cell growth? Do they inactivate growth brakes or are they just a whim of nature? To find clues for answering these questions scientists perform what are called loss-of-function analyses. They knock out (silence) the gene of interest in living cells or whole organisms and subsequently look for any changes in the cells' metabolism, physiology ...

Scented laundry products emit hazardous chemicals through dryer vents

2011-08-25
The same University of Washington researcher who used chemical sleuthing to deduce what's in fragranced consumer products now has turned her attention to the scented air wafting from household laundry vents. Findings, published online this week in the journal Air Quality, Atmosphere and Health, show that air vented from machines using the top-selling scented liquid laundry detergent and scented dryer sheet contains hazardous chemicals, including two that are classified as carcinogens. "This is an interesting source of pollution because emissions from dryer vents are ...

LAST 30 PRESS RELEASES:

Post-LLM era: New horizons for AI with knowledge, collaboration, and co-evolution

“Sloshing” from celestial collisions solves mystery of how galactic clusters stay hot

Children poisoned by the synthetic opioid, fentanyl, has risen in the U.S. – eight years of national data shows

USC researchers observe mice may have a form of first aid

VUMC to develop AI technology for therapeutic antibody discovery

Unlocking the hidden proteome: The role of coding circular RNA in cancer

Advancing lung cancer treatment: Understanding the differences between LUAD and LUSC

Study reveals widening heart disease disparities in the US

The role of ubiquitination in cancer stem cell regulation

New insights into LSD1: a key regulator in disease pathogenesis

Vanderbilt lung transplant establishes new record

Revolutionizing cancer treatment: targeting EZH2 for a new era of precision medicine

Metasurface technology offers a compact way to generate multiphoton entanglement

Effort seeks to increase cancer-gene testing in primary care

Acoustofluidics-based method facilitates intracellular nanoparticle delivery

Sulfur bacteria team up to break down organic substances in the seabed

Stretching spider silk makes it stronger

Earth's orbital rhythms link timing of giant eruptions and climate change

Ammonia build-up kills liver cells but can be prevented using existing drug

New technical guidelines pave the way for widespread adoption of methane-reducing feed additives in dairy and livestock

Eradivir announces Phase 2 human challenge study of EV25 in healthy adults infected with influenza

New study finds that tooth size in Otaria byronia reflects historical shifts in population abundance

nTIDE March 2025 Jobs Report: Employment rate for people with disabilities holds steady at new plateau, despite February dip

Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure

Fluoride in drinking water is associated with impaired childhood cognition

New composite structure boosts polypropylene’s low-temperature toughness

While most Americans strongly support civics education in schools, partisan divide on DEI policies and free speech on college campuses remains

Revolutionizing surface science: Visualization of local dielectric properties of surfaces

LearningEMS: A new framework for electric vehicle energy management

Nearly half of popular tropical plant group related to birds-of-paradise and bananas are threatened with extinction

[Press-News.org] Gene study sheds new light on origins of British men