(Press-News.org) ATS 2012, SAN FRANCISCO –The severity of sleep disordered breathing and nocturnal hypoxemia independently predict both glycosylated hemoglobin (HbA1c) levels and type 2 diabetes mellitus (T2DM), according to a new study.
"Because people with obstructive sleep apnea syndrome (OSAS) are often overweight or obese it has been difficult to interpret earlier studies of the relationship between sleep disordered breathing and metabolic disorders," said Brian Kent, MBBCh, research fellow at St. Vincent's University Hospital in Dublin. "We found that obstructive sleep apnea syndrome (OSAS) severity and low nocturnal oxygen levels were significant independent predictors of prevalent T2DM and HbA1c levels, even after adjustment for a number of confounding variables, including obesity."
The research will be presented at the ATS 2012 International Conference in San Francisco.
The study involved 7,886 prospectively assessed subjects from 22 sleep laboratories in 16 European countries. All subjects completed overnight sleep studies.
After adjustment for comorbidities and demographic and anthropometric variables, moderate and severe OSAS were each significant (P=.003) predictors of having a diagnosis of T2DM. Apnea/hypopnea index, oxyhemoglobin desaturation index, and mean oxygen saturation (SpO2) were significant (P END
Severity of sleep disordered breathing predicts glycemic health
2012-05-23
ELSE PRESS RELEASES FROM THIS DATE:
Oniqua Announces Major Enhancements to Material and Catalog Standards Database Solution
2012-05-23
Oniqua MRO Analytics (www.oniqua.com), the leading provider of analytics-based MRO optimization solutions for asset-intensive organizations, today announced significant enhancements to its Oniqua Standards Dictionary (OSD) database solution.
Available on an online subscription basis, OSD is a comprehensive material and catalog standards environment specifically designed, built and optimized for asset-intensive industries.
OSD 3.0 maximizes efficiencies in cataloging while minimizing inconsistencies and errors in completed cataloged records. It is designed to assist ...
Viral infections in infancy are not associated with wheezing symptoms in later childhood
2012-05-23
ATS 2012, SAN FRANCISCO – The number of viral infections during infancy is not associated with wheezing later in childhood, according to a new study from researchers in the Netherlands. While viral illnesses with wheezing in infancy predicted wheezing later in childhood, this association was due in part to decreased neonatal lung function.
"Viral infections in infancy, particularly rhinovirus, are thought to be a risk factor for later asthma development, but it is unclear whether this association is due to the viruses themselves or whether rhinovirus-associated wheeze ...
Long-term ICS use reduces pleural effusion in patients with CAP
2012-05-23
ATS 2012, SAN FRANCISCO – Prior treatment with inhaled corticosteroids in patients with respiratory disorders who develop community acquired pneumonia (CAP) is associated with a lower incidence and severity of parapneumonic effusion, according to a new study from researchers in Spain.
A parapneumonic effusion is a type of pleural effusion (excess fluid that accumulates between the two pleural layers, the fluid-filled space that surrounds the lungs) that arises as a result of a pneumonia, lung abscess, or bronchiectasis.
"Long-term treatment with inhaled corticosteroids ...
Tiny implanted coil improves lung function in patients with severe emphysema
2012-05-23
ATS 2012, SAN FRANCISCO – A tiny, resilient metal wire designed to gather and compress diseased lung tissue may offer relief to patients with severe heterogeneous emphysema, a subtype of the disease that involves specific, usually isolated areas of the lungs, according to the results of a multicenter international trial conducted in the Netherlands, Germany and France. The wire, called a lung volume reduction coil (LVRC), can be easily implanted and is designed to take the place of more invasive procedures used to improve the lung function of emphysema patients.
The study ...
Study shows antibiotic improves respiratory function in lung transplant patients
2012-05-23
ATS 2012, SAN FRANCISCO – Researchers in the United Kingdom have determined that azithromycin, a broad-spectrum antibiotic that also has anti-inflammatory properties, can be an effective treatment option for patients suffering from bronchiolitis obliterans syndrome (BOS), a life-threatening complication that occurs in the majority of patients following lung transplantation.
BOS is the leading cause of mortality after the first year following transplantation, and occurs in part when the body repeatedly rejects the transplanted lung tissue. The syndrome causes the airways ...
P. aeruginosa bacteria associated with increased hospitalizations in COPD patients
2012-05-23
ATS 2012, SAN FRANCISCO – Patients with chronic obstructive pulmonary disease (COPD) who become infected with the bacterium Pseudomonas aerguinosa are more likely to have worse clinical outcomes and experience more hospitalizations during the course of their disease than COPD patients who are not infected, according to researchers from Buffalo, N.Y.
The study will be presented at the ATS 2012 International Conference in San Francisco.
Bacterial bronchial infection plays a key role in the course of COPD, causing chronic inflammation as well as acute exacerbations of ...
Mortality rates decrease, chronic disease rates increase among HIV+ ICU patients
2012-05-23
ATS 2012, SAN FRANCISCO – The expanded use of antiretrovirals, potent drugs used to treat retroviral infections such as human immunodeficiency virus (HIV), has been linked to significant decreases in hospital mortality rates among severely ill HIV-positive(HIV+) patients nationwide, primarily due to a decrease in opportunistic infections, according to a new study by researchers at Stanford University. Despite these encouraging data, the study also revealed that in this population, chronic diseases and bloodstream infections are on the rise.
The study results will be presented ...
Breast MRI helps predict chemotherapy's effectiveness
2012-05-23
OAK BROOK, Ill. – Magnetic resonance imaging (MRI) provides an indication of a breast tumor's response to pre-surgical chemotherapy significantly earlier than possible through clinical examination, according to a new study published online in the journal Radiology.
Women with breast cancer often undergo chemotherapy prior to surgery. Research has shown that women who receive this treatment, known as neoadjuvant chemotherapy, are more likely to achieve breast conservation than those receiving chemotherapy after surgery.
Clinicians track a patient's response to neoadjuvant ...
Researchers uncover new ways sleep-wake patterns are like clockwork
2012-05-23
Researchers at New York University and Albert Einstein College of Medicine of Yeshiva University have discovered new ways neurons work together to ease the transition between sleep and wakefulness. Their findings, which appear in the journal Neuron, provide additional insights into sleep-wake patterns and offer methods to explore what may disrupt them.
Their study explored the biological, or circadian, clocks of Drosophila fruit flies, which are commonly used for research in this area. This is because it is relatively easy to find mutants with malfunctioning biological ...
Mayo Clinic urologists present findings at American Urological Association Annual Meeting
2012-05-23
ROCHESTER, Minn. -- Mayo Clinic researchers will present findings on prostate cancer risk, screening, treatment and other urological research at the annual meeting of the American Urological Association May 19-23 in Atlanta. Mayo Clinic urologists will also be available to provide expert comment for reporters covering the conference.
Mayo Clinic studies that will be presented and their embargo dates include:
No negative impact on overall survival from post-prostate surgery hormone therapy
Embargoed until 10:30 a.m. ET Monday, May 21
In a first-of-its-kind study ...