(Press-News.org) A process developed to increase efficiency and productivity in Japanese car factories has helped improve stroke treatment at Barnes-Jewish Hospital, report researchers at Washington University School of Medicine in St. Louis.
By applying the principles of Toyota's lean manufacturing process, doctors sharply reduced the average time between patient arrival and treatment, known as door-to-needle time, from 58 to 37 minutes.
The findings are reported Oct. 18 in the journal Stroke. In an average year, the medical school's physicians treat 1,300 stroke patients at Barnes-Jewish.
Beginning stroke treatment earlier can help prevent the brain damage that causes paralysis and loss of speech after a stroke. The researchers say the drop in treatment time results from applying a key component of lean manufacturing to patient care: getting input from all members of the team to identify inefficient steps involved in the process.
"We sought suggestions from everyone involved, from the paramedics who bring in patients, to admitting clerks, radiology technologists, nurses and physicians," says senior author Jin-Moo Lee, MD, PhD, associate professor of neurology at Washington University School of Medicine in St. Louis and director of the cerebrovascular disease section in the Department of Neurology. "Once the inefficient steps were identified, we developed a completely new protocol that eliminated them. This new treatment protocol helped us achieve one of the fastest door-to-needle times in the country."
Barnes-Jewish has a dedicated stroke team capable of quickly evaluating and treating patients with tPA, which breaks up blood clots in the brain that cause strokes. The earlier it is given, the more effective tPA is at preventing permanent brain damage caused by stroke.
Because tPA can cause dangerous bleeding in the brain and throughout the body, the drug can no longer be given if too much time elapses after a stroke begins. At that point, its risk outweighs the potential benefit. Ideally, the drug must be given within 60 minutes after a stroke begins, a period known as the "golden hour."
"We already had very good door-to-needle times, but we thought that we could do better," Lee says. "So we put all of our team members in a room for two days and asked them to evaluate each step in the door-to-needle process."
Experts at Barnes-Jewish with experience using the principles of lean manufacturing in a healthcare setting helped facilitate the discussion.
"Identifying steps that are wasteful and do not add value is a primary goal of lean manufacturing," says David Jaques, MD, vice president of Surgical Services at Barnes-Jewish Hospital and a professor at the School of Medicine. "Lean has made it possible to speed the delivery of medication or blood, improve teamwork and communication and ensure that those caring for patients always have easy access to supplies and equipment."
One problem identified by the group was repeatedly moving patients from one location to another and back again. The staff decided it would be more efficient for paramedics to bring patients directly to the emergency department's CT scanner for evaluation rather than to a patient examination room.
The group also noted that some aspects of patient care performed in sequence instead could be carried out simultaneously with the addition of extra staff. With two treatment nurses per patient, for example, one nurse can put in an IV while another gets medications. A neurologist and an emergency department physician also were assigned tasks that could be performed at the same time to speed patient care.
"We also added new specialties to the treatment team," Lee says. "We asked social workers to help identify people who were with the patient when the suspected stroke began. While they are talking with family members or co-workers, we can begin the initial assessment."
Finally, lab work for the patients was taking too long.
"Where we could, we instituted lab tests that could be performed at the bedside in minutes instead of sending the blood to the lab and waiting 30 minutes or more for results," Lee says.
The new treatment procedures were implemented in February 2011. The changes not only lowered average door-to-needle times by nearly 40 percent, but they also increased the percent of patients treated within "the golden hour" from 52 - 78 percent.
After the new procedures were put in place, the researchers monitored patients for side effects of treatment, including hemorrhages, and to make sure the accelerated process did not result in more patients getting the clot-busting drug when they were later determined to be stroke free. Neither of these negative outcomes increased.
Accelerating door-to-needle times for stroke treatment is only one example of how lean principles can be applied to improve patient care. Barnes-Jewish has already used lean principles to improve the delivery of blood products to patients, enhance patient access to radiological procedures, create more efficient operating room procedures and shorten hospital stays, according to Jaques.
"Lean principles used in manufacturing can be applied to patient care to create a higher quality, safer and more efficient hospital," Jaques says.
INFORMATION:
Ford AL, Williams JA, Spencer M, McCammon C, Khoury N, Sampson T, Panagos P, Lee J-M. Reducing door-to-needle times using Toyota's lean manufacturing principles and value stream analysis. Stroke, Oct. 18, 2012.
This study was supported by the National Institutes of Health (NIHK23NS069807), the Specialized Programs of Translational Research in Acute Stroke grant, (NIH5P50NS055977), and the Institute of Clinical and Translational Sciences at Washington University (UL1 TR000448).
Washington University School of Medicine's 2,100 employed and volunteer faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Children's hospitals. The School of Medicine is one of the leading medical research, teaching and patient care institutions in the nation, currently ranked sixth in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Children's hospitals, the School of Medicine is linked to BJC HealthCare.
Stroke patients benefit from carmaker's efficiency
2012-10-19
ELSE PRESS RELEASES FROM THIS DATE:
No antibodies, no problem
2012-10-19
Researchers at the Johns Hopkins Bloomberg School of Public Health have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene. Unlike humans and other animals, insects do not make antibodies to target specific infections. According to the Johns Hopkins researchers, mosquitoes use a mechanism known as alternative splicing to arrange different combinations of binding domains, encoded by the same AgDscam gene, into protein ...
Study shows breastfeeding reduced risk for ER/PR-negative breast cancer
2012-10-19
October 18, 2012 -- Breast-feeding reduces the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to a study conducted at Columbia University's Mailman School of Public Health. Researchers examined the association between reproductive risk factors — such as the number of children a woman delivers, breast-feeding and oral contraceptive use – and found an increased risk for estrogen receptor- and progesterone receptor- (ER/PR) negative breast cancer in women who do not breast-feed. The results also indicated that having three ...
Study shows elevated risk of blood clots in women taking birth control containing drospirenone
2012-10-19
OAKLAND, Calif., Oct. 18— A U.S. Food and Drug Administration-funded study led by the Kaiser Permanente Northern California Division of Research found an increased risk of arterial thrombotic events (ATE) and venous thromboembolic events (VTE) — commonly referred to as blockage of arteries and blood clots, respectively — associated with drospirenone-containing birth control pills compared to four low-dose estrogen combined hormonal contraceptives.
The study appears in the current online issue of Contraception.
"We found that starting use of drospirenone-containing combined ...
Caltech modeling feat sheds light on protein channel's function
2012-10-19
PASADENA, Calif.—Chemists at the California Institute of Technology (Caltech) have managed, for the first time, to simulate the biological function of a channel called the Sec translocon, which allows specific proteins to pass through membranes. The feat required bridging timescales from the realm of nanoseconds all the way up to full minutes, exceeding the scope of earlier simulation efforts by more than six orders of magnitude. The result is a detailed molecular understanding of how the translocon works.
Modeling behavior across very different timescales is a major ...
Depression, shortened telomeres increase mortality in bladder cancer patients
2012-10-19
HOUSTON - Low depressive symptoms and a longer telomere length are compelling factors that contribute to a prolonged life for bladder cancer patients according to researchers at The University of Texas MD Anderson Cancer Center.
In an observational study, a team of MD Anderson researchers analyzed clinical and behavioral data collected from 464 bladder cancer patients, according to research presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research.
"This is the first study of its kind that analyzes bladder cancer outcomes," ...
Bicycle infrastructure can reduce risk of cycling injuries by half: UBC study
2012-10-19
Certain types of routes carry much lower risk of injury for cyclists, according to a new University of British Columbia study on the eve of Vancouver's Bike to Work Week.
The study, published today in the American Journal of Public Health, analyzed the cause of 690 cycling injuries in Vancouver and Toronto from 2008 to 2009 and various route types and infrastructure.
The greatest risk to cyclists occurs when they share major streets with parked cars, with no bike lanes present – like on Broadway in Vancouver or Dundas Street in Toronto. Without a designated space on ...
AMP reports on possibilities, challenges, and applications of next-generation sequencing
2012-10-19
Bethesda, MD, October 18, 2012 The Association for Molecular Pathology (AMP) published the
report of the Whole Genome Analysis (WGA) Working Group of the AMP Clinical Practice Committee
in the November 2012 issue of The Journal of Molecular Diagnostics (JMD). Titled "Opportunities and
Challenges Associated with Clinical Diagnostic Genome Sequencing," the timely report provides a
detailed and compelling overview of the landscape of next generation sequencing (NGS) technology
and its clinical relevance and impact on improving patient care. The issues addressed in the ...
First-of-its-kind self-assembled nanoparticle for targeted and triggered thermo-chemotherapy
2012-10-19
Boston, MA— Excitement around the potential for targeted nanoparticles (NPs) that can be controlled by stimulus outside of the body for cancer therapy has been growing over the past few years. More specifically, there has been considerable attention around near-infrared (NIR) light as an ideal method to stimulate nanoparticles from outside the body. NIR is minimally absorbed by skin and tissue, has the ability to penetrate deep tissue in a noninvasive way and the energy from NIR light can be converted to heat by gold nanomaterials for effective thermal ablation of diseased ...
Conservation scientists look beyond greenbelts to connect wildlife sanctuaries
2012-10-19
We live in a human-dominated world. For many of our fellow creatures, this means a fragmented world, as human conduits to friends, family, and resources sever corridors that link the natural world. Our expanding web of highways, cities, and intensive agriculture traps many animals and plants in islands and cul-de-sacs of habitat, held back by barriers of geography or architecture from reaching mates, food, and wider resources.
A team of researchers, managers, and ecological risk assessors review the current state-of-the-art in landscape connectivity planning, offering ...
Solar power is contagious
2012-10-19
People are more likely to install a solar panel on their home if their neighbors have one, according to a Yale and New York University study in the journal Marketing Science.
The researchers studied clusters of solar installations throughout California from January 2001 to December 2011 and found that residents of a particular zip code are more likely to install solar panels if they already exist in that zip code and on their street.
"We looked at the influence that the number of cumulative adoptions—the number of people who already installed solar panels in a zip ...