PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Anesthesia type affects outcomes of bilateral knee replacement surgery

Anesthesia type affects outcomes of bilateral knee replacement surgery
2012-10-26
(Press-News.org) Using regional anesthesia rather than general anesthesia reduces the need for blood transfusions in patients undergoing bilateral total knee replacement, according to a new study by researchers at Hospital for Special Surgery, in New York City.

Currently, the majority of bilateral knee replacements in the United States (as well as single knee replacements) are performed under general anesthesia, and researchers say that a regional anesthesia known as neuraxial anesthesia should be promoted for these procedures.

"The use of neuraxial anesthesia may not always be feasible in every patient, but it should be considered more frequently," said Stavros Memtsoudis, M.D., Ph.D., director of Critical Care Services at Hospital for Special Surgery (HSS) in New York City, who led the study. "You shouldn't be asking doctors who don't use neuraxial anesthesia in their daily practice to suddenly switch over and start doing it, but there is a lot of education that needs to be done in terms of training residents and orthopedic surgeons to point out the impact of the choice of anesthetic technique on outcomes beyond the operating room." The study appears online ahead of print in the journal Regional Anesthesia and Pain Medicine.

Despite its advantages, bilateral knee replacement is associated with an increased risk of complications, compared with the alternative of operating on one knee at a time. Neuraxial anesthesia involves injecting medication into the fatty tissue that surrounds the nerve roots in the spine (known as an epidural) or into the cerebrospinal fluid that surrounds the spinal cord.

For the last two decades, HSS has increasingly used regional anesthesia for orthopedic procedures, because of a growing body of evidence showing favorable results compared with general anesthesia.

Because the influence of anesthesia on perioperative outcomes after bilateral total knee replacement is unknown, researchers at Hospital for Special Surgery conducted a retrospective review of all bilateral knee replacements performed between 2006 and 2010 using Premier Perspective. This administrative database contains discharge information from approximately 400 acute care hospitals located throughout the United States. The study population included 22,253 patients, but the type of anesthesia used was unclear in 6,566 of the patients. Of the 15,687 patients where anesthesia type could be identified, 6.8% received neuraxial anesthesia, 80.1% received general anesthesia, and 13.1% received a combination of both. The three groups had similar comorbidity burdens.

The investigators discovered that patients receiving neuraxial anesthesia were less likely to receive blood transfusions (28.5%) than patients receiving general anesthesia (44.7%) or the combination (38.0%) (P

[Attachments] See images for this press release:
Anesthesia type affects outcomes of bilateral knee replacement surgery

ELSE PRESS RELEASES FROM THIS DATE:

Glass: Characterizing with precision and efficiency

2012-10-26
At home, in the car or with industrial processes – glass is a universal material. Its properties are so extraordinary that frequently there are no alternatives to this material. Take, for example, high-temperature fuel cells, in which layers of ceramics and metals are alternately attached to each other: to ensure no explosive hydrogen escapes, the metal and ceramic layers must be firmly bound to each other, and the seam must be sealed tight. Only glass can accomplish this type of seal – and here, we are specifically referring to solder glass. But how does glass behave at ...

Scientists step up hunt for bacterial genes tied to Lyme disease

Scientists step up hunt for bacterial genes tied to Lyme disease
2012-10-26
Investigators at The University of Texas Health Science Center at Houston (UTHealth) have accelerated the search for the bacterial genes that make the Lyme disease bacterium so invasive and persistent. The discovery could advance the diagnosis and treatment of this disease, which affects an estimated 30,000 Americans each year. The researchers have developed a new technique that allowed them to test 15 times more bacterial genes than had been evaluated in the previous 30 years to ascertain their roles in infection. Findings appeared Oct. 25 in the journal The Public Library ...

Hermit crabs socialize to evict their neighbors

Hermit crabs socialize to evict their neighbors
2012-10-26
Social animals usually congregate for protection or mating or to capture bigger prey, but a University of California, Berkeley, biologist has found that the terrestrial hermit crab has a more self-serving social agenda: to kick another crab out of its shell and move into a larger home. All hermit crabs appropriate abandoned snail shells for their homes, but the dozen or so species of land-based hermit crabs – popular terrarium pets – are the only ones that hollow out and remodel their shells, sometimes doubling the internal volume. This provides more room to grow, more ...

NASA sees Tropical Storm Son-tinh moving through South China Sea

NASA sees Tropical Storm Son-tinh moving through South China Sea
2012-10-26
NASA's Terra satellite got a good look at Tropical Storm Son-tinh moving through the South China Sea and headed for landfall in Vietnam. NASA's Terra satellite flew over Son-Tinh on Oct. 26 at 0305 UTC (Oct. 25 at 11:05 p.m. EDT) and the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument aboard captured a visible image of the storm. At the time, Son-tinh's western edge had already moved away from the Philippines. The image revealed powerful thunderstorms in the northwestern quadrant of the storm, and in the storm's center. On Oct. 26 at 1500 UTC, Tropical ...

Drug shows promise in animal model of Alzheimer's and Parkinson's with dementia

2012-10-26
New research presented in October at the 6th Neurodegenerative Conditions Research and Development Conference in San Francisco demonstrates the role of the investigational compound IRX4204 in alleviating cognitive decline in animal models of Alzheimer's disease (AD). The presentation entitled "Investigation of the RXR-specific agonist IRX4204 as a Disease Modifying Agent of Alzheimer's Disease Neuropathology and Cognitive Impairment" was made by lead researcher Giulio Maria Pasinetti, MD, PhD, of the Mount Sinai School of Medicine in New York City. IRX4204 is a retinoid ...

Stroke survivors who smoke raise risk of more strokes, heart attack, death

2012-10-26
Stroke survivors who smoke put themselves at a greater risk of additional strokes, heart attack or death than those who never smoked, according to new research in the American Heart Association's journal Stroke. Those who quit smoking before their stroke also had less risk of poorer outcomes than current smokers, researchers found. Researchers in Melbourne, Australia, tracked 1,589 patients who experienced a first or recurrent stroke in 1996-99. They followed them for 10 years, using medical records and in-person and telephone interviews, and tracked demographics, ...

C'est difficile

2012-10-26
In a new study out today, researchers used mice to identify a combination six naturally occurring bacteria that eradicate a highly contagious form of Clostridium difficile, an infectious bacterium associated with many hospital deaths. Three of the six bacteria have not been described before. This work may have significant implications for future control and treatment approaches. The researchers found that this strain of C. difficile, known as O27, establishes a persistent, prolonged contagious period, known as supershedding that is very difficult to treat with antibiotics. ...

Researchers at the doorstep of stem cell therapies for MS, other myelin disorders

2012-10-26
When the era of regenerative medicine dawned more than three decades ago, the potential to replenish populations of cells destroyed by disease was seen by many as the next medical revolution. However, what followed turned out not to be a sprint to the clinic, but rather a long tedious slog carried out in labs across the globe required to master the complexity of stem cells and then pair their capabilities and attributes with specific diseases. In a review article appearing today in the journal Science, University of Rochester Medical Center scientists Steve Goldman, ...

Traditional fisheries management approach jeopardizes marine ecosystems worldwide

Traditional fisheries management approach jeopardizes marine ecosystems worldwide
2012-10-26
STONY BROOK, NY– In a Perspectives article, "The Risks of Overfishing," published today in the journal Science, Dr. Ellen K. Pikitch, executive director of the Institute for Ocean Conservation Science and professor at Stony Brook University, cautions against continuing traditional fisheries management. According to Dr. Pikitch, current and recent studies demonstrate the need for "a more precautionary approach to fisheries management, in which fishing is restricted to those places and amounts where it can be conducted safely and with minimal risk of jeopardizing the integrity ...

'Adoption activity days' can help children find new families

2012-10-26
Children's parties or activity days, where prospective adopters meet children awaiting adoption, could be part of the solution to the current adoption crisis, according to research that will be showcased during the Economic and Social Research Council (ESRC) Festival of Social Science. "Such parties or activity days went out of fashion in the 1980s but no one is sure why," says Katherine Runswick-Cole of Manchester Metropolitan University who led the research. "However, our pilot study has shown an overwhelmingly positive response from practitioners, adopters and the ...

LAST 30 PRESS RELEASES:

New study reveals how RNA travels between cells to control genes across generations

Women health sector leaders good for a nation’s wealth, health, innovation, ethics

‘Good’ cholesterol may be linked to heightened glaucoma risk among over 55s

GLP-1 drug shows little benefit for people with Parkinson’s disease

Generally, things really do seem better in morning, large study suggests

Juicing may harm your health in just three days, new study finds

Forest landowner motivation to control invasive species depends on land use, study shows

Coal emissions cost India millions in crop damages

$10.8 million award funds USC-led clinical trial to improve hip fracture outcomes

University Hospitals Cleveland Medical Center among most reputable academic medical centers

Emilia Morosan on team awarded Kavli Foundation grant for quantum geometry-enabled superconductivity

Unlock sales growth: Implement “buy now, pay later” to increase customer spending

Research team could redefine biomedical research

Bridging a gap in carbon removal strategies

Outside-in signaling shows a route into cancer cells

NFL wives bring signature safe swim event to New Orleans

Pickleball program boosts health and wellness for cancer survivors, Moffitt study finds

International Alzheimer’s prevention trial in young adults begins

Why your headphone battery doesn't last

Study probes how to predict complications from preeclampsia

CNIC scientists design an effective treatment strategy to prevent heart injury caused by a class of anticancer drugs

NYU’s Yann LeCun a winner of the 2025 Queen Elizabeth Prize for Engineering

New study assesses impact of agricultural research investments on biodiversity, land use

High-precision NEID spectrograph helps confirm first Gaia astrometric planet discovery

ABT-263 treatment rejuvenates aged skin and enhances wound healing

The challenge of pursuit – how saccades enable mammals to simultaneously chase prey and navigate through complex environments

Music can touch the heart, even inside the womb

Contribution of cannabis use disorder to new cases of schizophrenia has almost tripled over the past 17 years

Listening for multiple mental health disorders

Visualization of chemical phenomena in the microscopic world using semiconductor image sensor

[Press-News.org] Anesthesia type affects outcomes of bilateral knee replacement surgery