PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

New understanding of nerve damage caused by spinal cord injury could improve treatment design

New understanding of nerve damage caused by spinal cord injury could improve treatment design
2013-01-04
(Press-News.org) New Rochelle, NY, January 3, 2013—More than half of traumatic spinal cord injuries (SCI) in humans are cervical lesions, resulting in chronic loss of limb function. A better understanding of the link between the neurologic damage caused by SCI, spontaneous motor function recovery, and long-term motor deficits would lead to better therapeutic approaches, as discussed in an article in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal of Neurotrauma website at http://www.liebertpub.com/neu.

About 70% of human traumatic SCIs are incomplete, but the destruction of critical nerve fibers disrupts the signals normally sent between the brain and spinal cord beyond the site of the injury, resulting in locomotor impairment and paralysis. Elisa López-Dolado, Ana Lucas-Osma, and Jorge Collazos-Castro, Hospital Nacional de Parapléjicos Finca La Peraleda, Toledo, Spain, simulated a C6 partial SCI in adult rats and analyzed their recovery of motor function over four months.

The authors report extensive kinetic, anatomical, and electrophysiological data that demonstrate how the animals compensate for the permanent loss of some motor function. In the article "Dynamic Motor Compensations with Permanent, Focal Loss of Forelimb Force after Cervical Spinal Cord Injury," they propose that a premotoneuronal system in the cervical spine may be involved in the production and chronic nature of limb impairment, which could have important implications for the design of future treatment methods.

"This paper is important to the spinal cord injury field because it provides a comprehensive assessment of motor performance up to four months after cervical spinal cord injury," says Deputy Editor of Journal of Neurotrauma W. Dalton Dietrich, III, PhD, Scientific Director, The Miami Project to Cure Paralysis, and Kinetic Concepts Distinguished Chair in Neurosurgery, Professor of Neurological Surgery, Neurology and Cell Biology at University of Miami Leonard M. Miller School of Medicine, Lois Pope LIFE Center. "Force and kinematic data identifying progressive sensorimotor compensatory processes indicate new targets for therapeutic strategies to promote recovery and repair."



INFORMATION:

About the Journal

Journal of Neurotrauma is an authoritative peer-reviewed journal published 24 times per year in print and online that focuses on the latest advances in the clinical and laboratory investigation of traumatic brain and spinal cord injury. Emphasis is on the basic pathobiology of injury to the nervous system, and the papers and reviews evaluate preclinical and clinical trials targeted at improving the early management and long-term care and recovery of patients with traumatic brain injury. Journal of Neurotrauma is the Official Journal of the National Neurotrauma Society and the International Neurotrauma Society. Complete tables of content and a sample issue may be viewed on the Journal of Neurotrauma website at http://www.liebertpub.com/neu.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Therapeutic Hypothermia and Temperature Management, Tissue Engineering, and Brain Connectivity. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 70 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website at http://www.liebertpub.com.

Mary Ann Liebert, Inc. 140 Huguenot St., New Rochelle, NY 10801-5215
Phone: (914) 740-2100 (800) M-LIEBERT Fax: (914) 740-2101
www.liebertpub.com


[Attachments] See images for this press release:
New understanding of nerve damage caused by spinal cord injury could improve treatment design

ELSE PRESS RELEASES FROM THIS DATE:

Carbon in Vesta's craters

Carbon in Vestas craters
2013-01-04
The protoplanet Vesta has been witness to an eventful past: images taken by the framing camera onboard NASA's space probe Dawn show two enormous craters in the southern hemisphere. The images were obtained during Dawn's year-long visit to Vesta that ended in September 2012. These huge impacts not only altered Vesta's shape, but also its surface composition. Scientists under the lead of the Max Planck Institute for Solar System Research in Katlenburg-Lindau in Germany have shown that impacting small asteroids delivered dark, carbonaceous material to the protoplanet. In the ...

Planets abound

Planets abound
2013-01-04
PASADENA, Calif.—Look up at the night sky and you'll see stars, sure. But you're also seeing planets—billions and billions of them. At least. That's the conclusion of a new study by astronomers at the California Institute of Technology (Caltech) that provides yet more evidence that planetary systems are the cosmic norm. The team made their estimate while analyzing planets orbiting a star called Kepler-32—planets that are representative, they say, of the vast majority in the galaxy and thus serve as a perfect case study for understanding how most planets form. "There's ...

Improving DNA amplification from problematic plants

2013-01-04
The polymerase chain reaction (PCR) is a common technique used to amplify, or copy, pieces of DNA. Amplified DNA is then used in genetic analyses for everything from medicine to forensics. In plant research, PCR is a vital step in detecting and sequencing genes, and its applications are endless. However, compounds found in plants often inhibit PCR. Researchers at the University of Southern Mississippi discovered that the use of an additive allows PCR to successfully amplify DNA from once problematic plants. PCR is widely used in plant sciences but is not 100 percent ...

Plvap/PV1 critical to formation of the diaphragms in endothelial cells

2013-01-04
PV1 expression in vascular endothelium is required for survival PV1 is required for the formation of stomatal and fenestral diaphragms Lack of diaphragms in fenestrated endothelia causes vascular leak of plasma proteins Vascular leak results in severe hypoproteinemia and hypertriglyceridemia Dartmouth scientists have demonstrated the importance of the gene Plvap and the structures it forms in mammalian physiology in a study published in December by the journal Developmental Cell. "The knowledge generated and the animal models created will allow a better understanding ...

Finding Chicago's food gardens with Google Earth

2013-01-04
Urban agriculture is promoted as a strategy for dealing with food insecurity, stimulating economic development, and combating diet-related health problems in cities. However, up to now, no one has known how much gardening is taking place in urban areas. Researchers at the University of Illinois have developed a methodology that they used to quantify the urban agriculture in Chicago. John Taylor, a doctoral candidate working with crop sciences researcher Sarah Taylor Lovell, was skeptical about the lists of urban gardens provided to him by local non-governmental organizations ...

Dopamine-receptor gene variant linked to human longevity

2013-01-04
Irvine, Calif., Jan. 3, 2013 — A variant of a gene associated with active personality traits in humans seems to also be involved with living a longer life, UC Irvine and other researchers have found. This derivative of a dopamine-receptor gene – called the DRD4 7R allele – appears in significantly higher rates in people more than 90 years old and is linked to lifespan increases in mouse studies. Robert Moyzis, professor of biological chemistry at UC Irvine, and Dr. Nora Volkow, a psychiatrist who conducts research at the Brookhaven National Laboratory and also directs ...

2 NASA satellites see Cyclone Dumile over La Reunion and Mauritius

2 NASA satellites see Cyclone Dumile over La Reunion and Mauritius
2013-01-04
NASA's Aqua and Terra satellites captured visible and infrared data on Tropical Cyclone Dumile as it slammed into the islands of La Reunion and Mauritius in the Southern Indian Ocean. The Moderate Resolution Imaging Spectroradiometer (MODIS) instrument that flies aboard NASA's Terra satellite captured a visible image of Cyclone Dumile on Jan. 3, 2013 at 0650 UTC (1:50 a.m. EST/U.S.) The image showed Dumile's center was about 85 nautical miles (97.8 miles/157.4 km) northwest of Reunion Island and Mauritius, and the strongest thunderstorms appeared to be southwest of the ...

NASA sees Tropical Depression Sonamu form near Philippines

NASA sees Tropical Depression Sonamu form near Philippines
2013-01-04
The first Tropical Depression of 2013 formed the western North Pacific Ocean today, and NASA's Terra satellite captured an infrared image of the "birth." Tropical Depression Sonamu, otherwise known as Tropical Depression 01W developed near 8.6 north latitude and 118.6 east longitude, about 185 nautical miles (213 miles/342.6 km) northwest of Zamboanga, Philippines. Sonamu's center is located in the Sulu Sea and is expected to cross the southern end of Palawan before moving into the open waters of the South China Sea. Sonamu developed from low pressure System 92W. At ...

New rat model for muscle regeneration after trauma-related soft tissue injury

New rat model for muscle regeneration after trauma-related soft tissue injury
2013-01-04
New Rochelle, NY, January 3, 2013—Penetrating soft tissue injuries that may be caused by bullet wounds or motor vehicle accidents, or exposure to explosive devices in military settings, can cause muscle loss resulting in functional disability and cosmetic deformity. Efforts underway to develop tissue engineering solutions to repair and replace damaged and lost muscle will benefit greatly from the availability of robust animal models to test these innovative therapeutic strategies. A new rat model that simulates traumatic or surgical muscle tissue loss in humans is described ...

Best evidence yet that dinosaurs used feathers for courtship

2013-01-04
(Edmonton) A University of Alberta researcher's examination of fossilized dinosaur tail bones has led to a breakthrough finding: some feathered dinosaurs used tail plumage to attract mates, much like modern-day peacocks and turkeys. U of A Paleontology researcher Scott Persons followed a chain of fossil evidence that started with a peculiar fusing together of vertebrae at the tip of the tail of four different species of dinosaurs, some separated in time and evolution by 45 million years. Persons says the final vertebrae in the tails of a group of dinosaurs called oviraptors ...

LAST 30 PRESS RELEASES:

Federal Trade Commission actions on prescription drugs, 2000-2022

Fluoride exposure during pregnancy linked to increased risk of childhood neurobehavioral problems, study finds

The Ukraine war caused migrating eagles to deviate from their usual flight plan

Endangered migrating eagles impacted by Ukraine war

Study explores association between fluoride exposure in pregnancy and neurobehavioral issues in young children

Using magnetic resonance spectroscopy to design safer, higher-performance lithium batteries

Should your exercise goals be in minutes or steps? Study suggests they are equally beneficial

Racial and ethnic inequities in cancer care continuity during the COVID-19 pandemic among those with SARS-CoV-2

Effect of sleep restriction on adolescent cognition by adiposity

Webb Telescope offers first glimpse of an exoplanet’s interior

Alkyl-aromatic hybrid micelles formed from emergent umbrella-shaped molecules

First study from the African Ancestry Neuroscience Research Initiative identifies key genes in the brain that account for higher rates of some brain disorders in Black Americans

NIH awards Coast-to-Coast Consortium $5.6 million for All of Us Research Program

Ben-Gurion University scientist hunts for drug candidate to treat brain tumors

New Health Blueprint maps healthier future for rural, underserved Southwest Virginia

Survival benefit associated with participation in clinical trials of anticancer drugs

Expanding on the fundamental principles of liquid movement

Chemical Insights Research Institute partners with Duke University and the East-West Center to examine dust and ash from devastating Hawai’ian wildfires

NCCN publishes new resource for patients with intestinal cancer type most have never heard of before diagnosis

Subduction zone splay faults compound hazards of great earthquakes

Record low Antarctic sea ice ‘extremely unlikely’ without climate change

After hundreds of years, study confirms Bermuda now home to cownose rays

Scientists uncover promising treatment target for resistant brain cancer

Revolutionizing cancer treatment by intracellular protein delivery using hybrid nanotubes

Chemist Julian West makes C&EN magazine’s ‘Talented 12’ list

Robot-phobia could exasperate hotel, restaurant labor shortage

Study offers new detail on how COVID-19 affects the lungs

Body’s ‘message in a bottle’ delivers targeted cancer treatment

1 in 4 parents say their teen consumes caffeine daily or nearly every day

What makes some brown algae shimmer and others not?

[Press-News.org] New understanding of nerve damage caused by spinal cord injury could improve treatment design