PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Binge drinking increases risk of Type 2 diabetes by causing insulin resistance

2013-01-31
(Press-News.org) Binge drinking causes insulin resistance, which increases the risk of Type 2 diabetes, according to the results of an animal study led by researchers at the Diabetes Obesity and Metabolism Institute at the Icahn School of Medicine at Mount Sinai. The authors further discovered that alcohol disrupts insulin-receptor signaling by causing inflammation in the hypothalamus area of the brain.

The results are published in the January 30 issue of the journal Science Translational Medicine.

"Insulin resistance has emerged as a key metabolic defect leading to Type 2 diabetes and coronary artery disease (CAD)," said Christoph Buettner, MD, PhD, senior author of the study and Associate Professor of Medicine (Endocrinology, Diabetes and Bone Disease). "Someone who regularly binge drinks even once a week, over many years, may remain in an insulin resistant state for an extended period of time, potentially years," said Dr. Buettner.

In this study, researchers treated rats with alcohol for three consecutive days to simulate human binge drinking. A control group received the same amount of calories. Once alcohol was no longer detectable in blood, glucose metabolism was studied through either glucose-tolerance tests or through controlled-insulin infusions. The rats treated with alcohol were found to have higher concentrations of plasma insulin than the control group, suggesting that insulin resistance may have been the cause of the impaired glucose tolerance.

High plasma insulin levels are a major component of the metabolic syndrome, a group of risk factors that occur together and increase the risk for Type 2 diabetes, coronary artery disease, and stroke.

"Previously it was unclear whether binge drinking was associated with an increased risk for diabetes, since a person who binge drinks may also tend to binge eat, or at least eat too much. Our data show for the first time that binge drinking induces insulin resistance directly and can occur independent of differences in caloric intake," said Claudia Lindtner, MD, first author of the study and an Associate Researcher of Medicine, Endocrinology, Diabetes and Bone Disease at the Icahn School of Medicine.

### About The Mount Sinai Medical Center The Mount Sinai Medical Center encompasses both The Mount Sinai Hospital and Icahn School of Medicine at Mount Sinai. Established in 1968, the Icahn School of Medicine is one of the leading medical schools in the United States, and is noted for innovation in education, biomedical research, clinical care delivery, and local and global community service. It has more than 3,400 faculty in 32 departments and 14 research institutes, and ranks among the top 20 medical schools both in National Institutes of Health (NIH) funding and by U.S. News & World Report.

The Mount Sinai Hospital, founded in 1852, is a 1,171-bed tertiary- and quaternary-care teaching facility and one of the nation's oldest, largest and most-respected voluntary hospitals. In 2012, U.S. News & World Report ranked The Mount Sinai Hospital 14th on its elite Honor Roll of the nation's top hospitals based on reputation, safety, and other patient-care factors. Mount Sinai is one of 12 integrated academic medical centers whose medical school ranks among the top 20 in NIH funding and by U.S. News & World Report and whose hospital is on the U.S. News & World Report Honor Roll. Nearly 60,000 people were treated at Mount Sinai as inpatients last year, and approximately 560,000 outpatient visits took place.

For more information, visit http://www.mountsinai.org/. Find Mount Sinai on: Facebook: http://www.facebook.com/mountsinainyc
Twitter @mountsinainyc
YouTube: http://www.youtube.com/mountsinainy END


ELSE PRESS RELEASES FROM THIS DATE:

Mount Sinai launches clinical trial to treat chronic pulmonary sarcoidosis

2013-01-31
Patients are currently being enrolled in the first clinical trial to investigate the efficacy of immunological therapy for chronic pulmonary sarcoidosis. The trial is being conducted by researchers at the Icahn School of Medicine at Mount Sinai. Mount Sinai has the largest Sarcoidosis Service in the world and is one of only two institutions in the country participating in the trial; the other is the University of Cincinnati. Mount Sinai is a National Institutes of Health Center of Excellence for research in sarcoidosis. "The current standard treatment for chronic pulmonary ...

New semiconductor research may extend integrated circuit battery life tenfold

2013-01-31
Researchers at Rochester Institute of Technology, international semiconductor consortium SEMATECH and Texas State University have demonstrated that use of new methods and materials for building integrated circuits can reduce power—extending battery life to 10 times longer for mobile applications compared to conventional transistors. The key to the breakthrough is a tunneling field effect transistor. Transistors are switches that control the movement of electrons through material to conduct the electrical currents needed to run circuits. Unlike standard transistors, which ...

Satellite image shows eastern US severe weather system

Satellite image shows eastern US severe weather system
2013-01-31
A powerful cold front moving from the central United States to the East Coast is wiping out spring-like temperatures and replacing them with winter-time temperatures with powerful storms in between. An image released from NASA using data from NOAA's GOES-13 satellite provides a stunning look at the powerful system that brings a return to winter weather in its wake. On Jan. 30 at 1825 UTC (1:25 p.m. EST), NOAA's GOES-13 satellite captured an image of clouds associated with the strong cold front. The visible GOES-13 image shows a line of clouds that stretch from Canada ...

NASA-NOAA's Suomi NPP satellite sees powerful Cyclone Felleng

NASA-NOAAs Suomi NPP satellite sees powerful Cyclone Felleng
2013-01-31
False-colored night-time satellite imagery from NASA-NOAA's Suomi NPP satellite clearly shows bands of thunderstorms wrapping into the eye of Cyclone Felleng as it parallels the coast of eastern Madagascar. The Visible Infrared Imager Radiometer Suite (VIIRS) aboard NASA-NOAA's Suomi NPP satellite captured a night-time image of Cyclone Felleng when it was located east of Madagascar (4:09 p.m. EST/Jan. 30 at 12:09 a.m. local time, Madagascar). The image was created at the University of Wisconsin-Madison and was false colored to reveal temperatures. The image shows powerful ...

Rutgers physics professors find new order in quantum electronic material

2013-01-31
Two Rutgers physics professors have proposed an explanation for a new type of order, or symmetry, in an exotic material made with uranium – a theory that may one day lead to enhanced computer displays and data storage systems and more powerful superconducting magnets for medical imaging and levitating high-speed trains. Their discovery, published in this week's issue of the journal Nature, has piqued the interest of scientists worldwide. It is one of the rare theory-only papers that this selective publication accepts. Typically the journal's papers describe results of ...

Archaic Native Americans built massive Louisiana mound in less than 90 days

Archaic Native Americans built massive Louisiana mound in less than 90 days
2013-01-31
Nominated early this year for recognition on the UNESCO World Heritage List, which includes such famous cultural sites as the Taj Mahal, Machu Picchu and Stonehenge, the earthen works at Poverty Point, La., have been described as one of the world's greatest feats of construction by an archaic civilization of hunters and gatherers. Now, new research in the current issue of the journal Geoarchaeology, offers compelling evidence that one of the massive earthen mounds at Poverty Point was constructed in less than 90 days, and perhaps as quickly as 30 days — an incredible ...

REACH news: European ombudsman takes up PETA complaint

2013-01-31
London – In response to a complaint by People for the Ethical Treatment of Animals (PETA), the European Ombudsman has launched an inquiry into the actions of the European Union (EU) agency responsible for the administration of the REACH chemical-testing program, which is expected to consume millions of animals in toxicity tests. PETA's complaint, submitted in July 2012, alleges that the European Chemicals Agency (ECHA) is not properly investigating cases in which animal testing could be avoided under the rules of REACH. PETA maintains that evidence derived from public documents ...

Researchers harness nature to produce the fuel of the future

2013-01-31
Hydrogen has tremendous potential as an eco-friendly fuel, but it is expensive to produce. Now researchers at Princeton University and Rutgers University have moved a step closer to harnessing nature to produce hydrogen for us. The team, led by Princeton chemistry professor Annabella Selloni, takes inspiration from bacteria that make hydrogen from water using enzymes called di-iron hydrogenases. Selloni's team uses computer models to figure out how to incorporate the magic of these enzymes into the design of practical synthetic catalysts that humans can use to produce ...

Patients can emit small, influenza-containing particles into the air during routine care

2013-01-31
[EMBARGOED FOR JAN. 31, 2013] A new study suggests that patients with influenza can emit small virus-containing particles into the surrounding air during routine patient care, potentially exposing health care providers to influenza. Published in The Journal of Infectious Diseases, the findings raise the possibility that current influenza infection control recommendations may not always be adequate to protect providers from influenza during routine patient care in hospitals. Werner E. Bischoff, MD, PhD, and colleagues from the Wake Forest School of Medicine in North Carolina ...

Social networking: Gen Xers connect online as often as they socialize in person

2013-01-31
ANN ARBOR--- Young adults in Generation X are as likely to connect with friends, family and co-workers online as they are in person, according to a University of Michigan study. In a typical month, adults in their late 30s report that they engaged in about 75 face-to-face contacts or conversations, compared to about 74 electronic contracts through personal emails or social media. "Given the speed of emerging technologies, it is likely that electronic contacts will continue to grow in the years ahead, eventually exceeding face-to-face interactions," says Jon D. Miller, ...

LAST 30 PRESS RELEASES:

Are lifetimes of big appliances really shrinking?

Pink skies

Monkeys are world’s best yodellers - new research

Key differences between visual- and memory-led Alzheimer’s discovered

% weight loss targets in obesity management – is this the wrong objective?

An app can change how you see yourself at work

NYC speed cameras take six months to change driver behavior, effects vary by neighborhood, new study reveals

New research shows that propaganda is on the rise in China

Even the richest Americans face shorter lifespans than their European counterparts, study finds

Novel genes linked to rare childhood diarrhea

New computer model reveals how Bronze Age Scandinavians could have crossed the sea

Novel point-of-care technology delivers accurate HIV results in minutes

Researchers reveal key brain differences to explain why Ritalin helps improve focus in some more than others

Study finds nearly five-fold increase in hospitalizations for common cause of stroke

Study reveals how alcohol abuse damages cognition

Medicinal cannabis is linked to long-term benefits in health-related quality of life

Microplastics detected in cat placentas and fetuses during early pregnancy

Ancient amphibians as big as alligators died in mass mortality event in Triassic Wyoming

Scientists uncover the first clear evidence of air sacs in the fossilized bones of alvarezsaurian dinosaurs: the "hollow bones" which help modern day birds to fly

Alcohol makes male flies sexy

TB patients globally often incur "catastrophic costs" of up to $11,329 USD, despite many countries offering free treatment, with predominant drivers of cost being hospitalization and loss of income

Study links teen girls’ screen time to sleep disruptions and depression

Scientists unveil starfish-inspired wearable tech for heart monitoring

Footprints reveal prehistoric Scottish lagoons were stomping grounds for giant Jurassic dinosaurs

AI effectively predicts dementia risk in American Indian/Alaska Native elders

First guideline on newborn screening for cystic fibrosis calls for changes in practice to improve outcomes

Existing international law can help secure peace and security in outer space, study shows

Pinning down the process of West Nile virus transmission

UTA-backed research tackles health challenges across ages

In pancreatic cancer, a race against time

[Press-News.org] Binge drinking increases risk of Type 2 diabetes by causing insulin resistance