Anesthesia increases success rates of turning breech babies, reduces delivery costs

(Press-News.org) STANFORD, Calif. — When a baby is in the breech position at the end of pregnancy, obstetricians can sometimes turn the baby head-down to enable a safer vaginal birth. In the past, women were not given anesthesia during the turning procedure, which requires the physician to push on the woman's abdomen while monitoring the baby with ultrasound. But a new study from the Stanford University School of Medicine and Lucile Packard Children's Hospital shows anesthesia is cost-effective because it increases the likelihood the procedure will work.

The turning procedure, called an external cephalic version, or simply a "version," can allow some women with breech babies to avoid a cesarean section and have a head-first vaginal delivery instead. Prior studies have shown that spinal or epidural anesthesia — similar to the anesthetic techniques offered during childbirth — can help more babies to be turned successfully. Many obstetricians still do not use anesthesia when doing a version.

"We've been looking at reasons physicians don't offer anesthesia during this procedure, and one reason may be that they think it may add extra costs," said the study's lead author, Brendan Carvalho, MD, associate professor of anesthesia at Stanford and chief of obstetric anesthesia at Packard Children's. "But our work shows that it doesn't add significant costs, and most likely reduces overall costs because more women can avoid cesareans."

The study was published online today in Anesthesia & Analgesia.

Because a breech vaginal delivery, in which a baby is born feet-first or bottom-first, is more dangerous for the mother and baby than a head-first vaginal delivery, many breech babies are delivered by cesarean section. But cesarean sections have their own disadvantages, such as increased risk of maternal hemorrhage, more pain and longer recovery times for the mother after birth, as well as higher hospital costs. As part of their effort to reduce cesarean rates, Packard Children's obstetric anesthesiologists have been offering anesthesia during version procedures for the last two years, making Packard Children's a Bay Area leader in studying and providing anesthesia for versions.

The new research drew upon data from several earlier studies that compared version success rates with and without anesthesia. The scientists also used national data on the cost of the version procedure with and without anesthesia, and the costs of vaginal and cesarean deliveries. All of the data was entered into a mathematical model that allowed the scientists to predict whether anesthesia use during a version was cost-effective.

The study found that using anesthesia increased average success rates of version procedures from 38 percent to 60 percent. Because it led to fewer cesareans, use of anesthesia also decreased the total cost of delivery by an average of $276; the range of cost differences estimated by the model extended from a $720 savings to a $112 additional cost.

Looking at the question of cost-effectiveness in a different way, the success rates of versions had to be improved at least 11 percent with anesthesia for the cost of the anesthesia to be negated, the researchers calculated.

Prior research has also shown that women are happier with version procedures when they receive anesthesia, Carvalho noted. "The pain of this procedure is variable, but it certainly is uncomfortable," he said. "If you have anesthesia, you feel pressure more than pain. Several studies have shown lower pain scores and higher patient satisfaction with anesthesia."

Abdominal muscle relaxation likely contributes to the higher success rates of the procedures performed with anesthesia, Carvalho said, adding that muscle relaxation caused by anesthesia may allow practitioners to apply less pressure to turn the baby. A previous study by these investigators demonstrated that anesthesia does not increase the risk of performing a version.

### Carvalho's collaborators at Stanford included Alex Macario, MD, professor of anesthesia, and Yasser El-Sayed, MD, professor of obstetrics and gynecology. Researchers from Stony Brook University in Stony Brook, N.Y., and University College London Hospital also contributed to the study.

There was no outside funding for the research. Information about Stanford's Department of Pediatrics is available at http://pediatrics.stanford.edu.

The Stanford University School of Medicine consistently ranks among the nation's top medical schools, integrating research, medical education, patient care and community service. For more news about the school, please visit http://mednews.stanford.edu. The medical school is part of Stanford Medicine, which includes Stanford Hospital & Clinics and Lucile Packard Children's Hospital. For information about all three, please visit http://stanfordmedicine.org/about/news.html.

Lucile Packard Children's Hospital at Stanford is an internationally recognized 311-bed hospital, research center and leading regional medical network providing the full complement of services for the health of children and expectant mothers. In partnership with the Stanford University School of Medicine, our world-class doctors and nurses deliver innovative, family-centered care in every pediatric and obstetric specialty, tailored to every patient. Packard Children's is annually ranked as one of the nation's best pediatric hospitals by U.S. News & World Report and is the only Northern California children's hospital with specialty programs ranked in the U.S. News Top 10. Learn more about us at http://www.lpch.org and about our continuing growth at growing.lpch.org. Friend us on Facebook, watch us on YouTube and follow us on Twitter.

Print media contact: Erin Digitale (650) 724-9175 (digitale@stanford.edu) Broadcast media contact: Winter Johnson at (650) 498-7956 (wijohnson@lpch.org)