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Chemists develop innovative nano-sensors for multiple proteins

2013-07-31
Chemists at Johannes Gutenberg University Mainz (JGU) have developed a new method for parallel protein analysis that is, in principle, capable of identifying hundreds or even thousands of different proteins. It could be used to detect the presence of viruses and identify their type in tiny samples. At the same time, it is very cost-effective and quick. "We see possible applications of this technique in medicine, where it could be used, for example, for the rapid diagnosis of a wide range of diseases. It would be almost as easy to use as a pregnancy test strip," said Professor ...

Microfluidic breakthrough in biotechnology

2013-07-31
Chemical flasks and inconvenient chemostats for cultivation of bacteria are likely soon to be discarded. Researchers from the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw were first to construct a microfluidic system allowing for merging, transporting and splitting of microdroplets. Since now, hundreds of different bacteria cultures can be maintained simultaneously in a single system, which could speed up the research on restistance of bacteria to antibiotics. We could safely say that without chemical flask there would be no chemistry at ...

Computational biology: Cells reprogrammed on the computer

2013-07-31
This is the first paper based solely on theoretical, yet practically proven, results of computational biology to be published in this journal. (DOI: 10.1002/stem.1473). All cells of an organism originate from embryonic stem cells, which divide and increasingly differentiate as they do so. The ensuing tissue cells remain in a stable state; a skin cell does not spontaneously change into a nerve cell or heart muscle cell. "Yet the medical profession is greatly interested in such changes, nonetheless. They could yield new options for regenerative medicine," says Professor ...

Male Holocaust survivors have a longer life-expectancy

2013-07-31
Male Holocaust survivors have a longer life expectancy compared to those who didn't experience the Holocaust, according to a recent study conducted at the University of Haifa jointly with Leiden University. The results have just been published in PLOS ONE. This is the first study to examine data on the entire Jewish Polish population that immigrated to Israel before and after World War II, using the population-wide official database of the National Insurance Institute of Israel. "Holocaust survivors not only suffered grave psychosocial trauma but also famine, malnutrition, ...

Another scientific proof of the difference in social perception between men and women

2013-07-31
"The Love Hormone", Oxytocin affects men and women differently in social contexts- in men it improves the ability to identify competitive relationships whereas in women it facilitates the ability to identify kinship. "These findings are in agreement with previous studies on the social differences between the sexes: women tend to be more communal and familial in their behavior, whereas men are more inclined to be competitive and striving to improve their social status", said Prof. Simone Shamay-Tsoory from the Dept. of Psychology at the University of Haifa who led the research. ...

The naked mole-rat's secret to staying cancer free

2013-07-31
Mice and rats have long since been a standard animal model for cancer research, mainly due to their short lifespan of four years on average and high incidence of cancer. Naked mole rats however, are a mystery among mammals. This social tiny African subterranean rodent has a maximum lifespan exceeding 30 years and most surprisingly, is cancer-resistant. The fact that so far, not a single incident of cancer has been detected makes the naked mole rat a fitting model for finding novel ways to fight cancer. Recently, a team of researchers from the University of Rochester ...

Scientists at Mainz University decode mechanisms of cell orientation in the brain

2013-07-31
When the central nervous system is injured, oligodendrocyte precursor cells (OPC) migrate to the lesion and synthesize new myelin sheaths on demyelinated axons. Scientists at the Institute of Molecular Cell Biology at Johannes Gutenberg University Mainz (JGU) have now discovered that a distinct protein regulates the direction and movement of OPC toward the wound. The transmembrane protein NG2, which is expressed at the surface of OPCs and down-regulated as they mature to myelinating oligodendrocytes, plays an important role in the reaction of OPC to wounding. The results ...

Insect-inspired super rubber moves toward practical uses in medicine

2013-07-31
The remarkable, rubber-like protein that enables dragonflies, grasshoppers and other insects to flap their wings, jump and chirp has major potential uses in medicine, scientists conclude in an article in the journal ACS Macro Letters. It evaluates the latest advances toward using a protein called resilin in nanosprings, biorubbers, biosensors and other applications. Kristi Kiick and colleagues explain that scientists discovered resilin a half-century ago in the wing hinges of locusts and elastic tendons of dragonflies. The extraordinary natural protein tops the best synthetic ...

Sensitive parenting can boost premature children's school performance

2013-07-31
Sensitive parenting helps protect against the negative effects of being born prematurely on children's school success, a new study has found. Children born prematurely are at risk of a variety of neurological impairments which can mean they are more likely to need special educational support when they reach school age. But a new study led by the University of Warwick shows that parents of very preterm and very low birthweight (VP/VLBW) children can increase their child's academic achievement through sensitive and cognitively stimulating parenting. Researchers looked ...

Progress in using ethanol to make key raw material now produced from oil

2013-07-31
Ethanol from corn and other plants could become the sustainable, raw material for a huge variety of products, from plastic packaging to detergents to synthetic rubber, that are currently petroleum-based. This was the conclusion of an article published in the ACS journal Industrial & Engineering Chemistry Research. Yingzhe Yu and colleagues point out that a chemical called ethylene, now produced from petroleum, is one of the most important raw materials for everyday products. Ethylene is used to make hundreds of products, including polyethylene, the world's most widely ...

Studying the emotions which cause opinions to change

2013-07-31
Social phenomena fascinate with their complexity, but are not easily understood. Pawel Sobkowicz, an independent researcher based in Warsaw, Poland, has developed a model to study the dynamics of normal people, called 'agents', and their response to a given piece of information, depending on their emotional state. In a study about to be published in EPJ B, the author shows that opinion dynamics differ depending on whether the agent is agitated or not. Key social questions of interest have been the object of previous studies using physics tools. The field of magnetic interactions ...

New protein discovered with vast potential for treatment of cancer and other diseases

2013-07-31
In cancer research, discovering a new protein that plays a role in cancer is like finding a key and a treasure map: follow the clues and eventually there could be a big reward. At least that's the hope from a new study published in the journal Nature that discovered a novel protein called ceramide-1 phosphate transport protein (CPTP) -- a finding that could eventually lead to the development of new drugs to treat a variety of cancers and other conditions involving inflammation and thrombosis, or blood clotting. The identification of CPTP was the result of an international ...

UT Austin researchers successfully spoof an $80 million yacht at sea

2013-07-31
AUSTIN, Texas — This summer, a radio navigation research team from The University of Texas at Austin set out to discover whether they could subtly coerce a 213-foot yacht off its course, using a custom-made GPS device. Led by assistant professor Todd Humphreys of the Department of Aerospace Engineering and Engineering Mechanics at the Cockrell School of Engineering, the team was able to successfully spoof an $80 million private yacht using the world's first openly acknowledged GPS spoofing device. Spoofing is a technique that creates false civil GPS signals to gain control ...

Georgia Tech uncovers iOS security weaknesses

2013-07-31
Researchers from the Georgia Tech Information Security Center (GTISC) have discovered two security weaknesses that permit installation of malware onto Apple mobile devices using seemingly innocuous applications and peripherals, uncovering significant security threats to the iOS platform. "Apple utilizes a mandatory app review process to ensure that only approved apps can run on iOS devices, which allows users to feel safe when using any iOS app," said GTISC Associate Director Paul Royal, also a research scientist in the College of Computing. "However, we have discovered ...

Sediment trapped behind dams makes them 'hot spots' for greenhouse gas emissions

2013-07-31
With the "green" reputation of large hydroelectric dams already in question, scientists are reporting that millions of smaller dams on rivers around the world make an important contribution to the greenhouse gases linked to global climate change. Their study, showing that more methane than previously believed bubbles out of the water behind small dams, appears in ACS' journal Environmental Science & Technology. Andreas Maeck and colleagues point out that the large reservoirs of water behind the world's 50,000 large dams are a known source of methane. Like carbon dioxide, ...

Study offers promising new direction for organ regeneration and tissue repair

2013-07-31
BOSTON – Because most human tissues do not regenerate spontaneously, advances in tissue repair and organ regeneration could benefit many patients with a wide variety of medical conditions. Now a research team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) and Dana-Farber/Boston Children's Cancer and Blood Disorders Center has identified an entirely new approach to enhance normal tissue growth, a finding that could have widespread therapeutic applications. Their findings were published on-line this week in the Proceedings of the National Academy ...

Chemical company giants stall with global economy

2013-07-31
The world's 50 largest chemical companies — with combined 2012 sales of almost $1 trillion and products that touch the lives of people everywhere — are the topic of the cover story in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society. In C&EN's annual snapshot of the sales, profits, R&D spending and other indicators, Senior Correspondent Alexander Tullo points out that the Asian and Middle Eastern juggernauts that shot up the top 50 rankings during the past decade ...

New poll shows minority populations support clinical trials to improve health of others

2013-07-31
ALEXANDRIA, Va.—July 31, 2013—Altruism is a strong motivating factor for clinical trial participation in the general population and even more so among several minority groups. A significant percentage of African-Americans (61%), Hispanics (57%) and Asians (50%) say it's very important to participate as a volunteer in a clinical trial to improve the health of others, compared to 47% of non-Hispanic whites, according to a new national public opinion poll commissioned by Research!America. These findings are tempered by the reality that participation remains disturbingly ...

3-D molecular syringes

2013-07-31
This news release is available in German. Abdominal pain, fever, diarrhoea -- these symptoms could point to an infection with the bacterium Yersinia. The bacterium's pathogenic potential is based on a syringe-like injection apparatus called injectisome. For the first time, an international team of researchers including scientists at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, has unraveled this molecular syringe's spatial conformation. The researchers were able to demonstrate that the length of Yersinia's injectisome's basal body, which ...

VCU physicists discover theoretical possibility of large, hollow magnetic cage molecules

2013-07-31
Virginia Commonwealth University researchers have discovered, in theory, the possibility of creating large, hollow magnetic cage molecules that could one day be used in medicine as a drug delivery system to non-invasively treat tumors, and in other emerging technologies. Approximately 25 years ago, scientists first made the discovery of C60 fullerene – better known as the Buckminster Fullerene – a molecule composed of 60 carbon molecules that formed a hollow cage. Due to its unique hollow cage structure the molecule offers serious technological potential because it could ...

Tiny, brightly shining silicon crystals could be safe for deep-tissue imaging

2013-07-31
BUFFALO, N.Y. — Tiny silicon crystals caused no health problems in monkeys three months after large doses were injected, marking a step forward in the quest to bring such materials into clinics as biomedical imaging agents, according to a new study. The findings, published online July 10 in the journal ACS Nano, suggest that the silicon nanocrystals, known as quantum dots, may be a safe tool for diagnostic imaging in humans. The nanocrystals absorb and emit light in the near-infrared part of the spectrum, a quality that makes them ideal for seeing deeper into tissue ...

Robots strike fear in the hearts of fish

2013-07-31
Brooklyn, N.Y.—The latest in a series of experiments testing the ability of robots to influence live animals shows that bio-inspired robots can not only elicit fear in zebrafish, but that this reaction can be modulated by alcohol. These findings may pave the way for new methodologies for understanding anxiety and other emotions, as well as substances that alter them. Maurizio Porfiri, associate professor of mechanical and aerospace engineering at the Polytechnic Institute of New York University (NYU-Poly) and Simone Macrì, a collaborator at the Istituto Superiore di Sanità ...

First experimental signs of a New Physics beyond the Standard Model

2013-07-31
The Standard Model, which has given the most complete explanation up to now of the universe, has gaps, and is unable to explain phenomena like dark matter or gravitational interaction between particles. Physicists are therefore seeking a more fundamental theory that they call "New Physics", but up to now there has been no direct proof of its existence, only indirect observation of dark matter, as deduced, among other things, from the movement of the galaxies. A team of physicists formed by the professor of Physics at Universitat Autònoma de Barcelona (UAB) Joaquim Matias, ...

Key factors for wireless power transfer

2013-07-31
WASHINGTON D.C., July 31, 2013 -- What happens to a resonant wireless power transfer system in the presence of complex electromagnetic environments, such as metal plates? A team of researchers explored the influences at play in this type of situation, and they describe in the American Institute of Physics' journal AIP Advances how efficient wireless power transfer can indeed be achieved in the presence of metal plates. The team discovered that resonance frequency matching, alignment of the magnetic field, and impedance matching are the most important factors for efficient ...

Binding together repelling atoms

2013-07-31
Basic chemistry tells us that a bond between atoms can form if it is energetically more favorable for the atoms to stick together than staying apart. This fundamentally requires an attractive force between the atoms. However, new theoretical predictions show that the combination of a repelling force and controlled noise from an environment can also have the surprising effect of leading to a bound state, although one with quite exotic properties. The research team consisting of Harvard postdoc Mikhail Lemeshko and former Harvard postdoc Hendrik Weimer* report their results ...
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