Blocking antioxidants in cancer cells reduces tumor growth in mice Many cancers have adapted to cope with high levels of immune system-produced free radicals, also referred to as reactive oxygen species, by overproducing antioxidant proteins. One of these ...

Silent RNAs express themselves in ALS disease RNA molecules, used by cells to make proteins, are generally thought to be "silent" when stowed in cytoplasmic granules. But a protein mutated in some ALS patients forms granules that permit translation of ...

First Nations adults have more than double the risk of end-stage kidney disease First Nations adults with diabetes have more than double the risk of end-stage kidney disease compared with non–First Nations adults, found a new study in CMAJ (Canadian ...

Johns Hopkins researchers show how a modified pacemaker strengthens failing hearts Findings advance opportunities for a 'pacemaker in a bottle' Johns Hopkins heart researchers are unraveling the mystery of how a modified pacemaker used to treat many patients ...

Evolution, Civil War history entwine in plant fossil with a tragic past Union Army forced freed slaves to dig canal where 120 million-year-old fossil plant was found COLLEGE PARK, Md – A fossil leaf fragment collected decades ago on a Virginia canal bank has been identified ...

Key found to restoring 'exhausted' HIV-fighting immune cells Protein could prove a promising new drug target Researchers have identified a protein that causes loss of function in immune cells combatting HIV. The scientists report in a paper appearing online Dec. 2 in ...

New evidence that 'gout' strongly runs in the family It's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientists at The University of Nottingham have confirmed ...

Researchers analyze growth potential in African bank loans In Africa, small women-owned business owners find it easier to obtain loans than their male counterparts. The reason for this distortion is that politicians and foreign aid organisations with their focus on bank ...

Congenital heart defects affects long-term developmental outcome Approximately one percent of all newborns in Switzerland are diagnosed with a congenital heart defect, roughly half of them require open heart surgery. Most children, including those with the most severe ...

New research shows obesity is an inflammatory disease New research in The FASEB Journal suggests that an abnormal amount of an inflammatory protein called PAR2 is present on abdominal fat tissues of overweight and obese humans and ...

EASAC report warns Europe on extreme weather event increase First comprehensive survey shows 60 percent rise over last 30 years of floods, droughts and storms Europe needs to plan for future probabilities of extreme weather. Heat waves, ...

Athletes and the words for actions A study investigates the role of the motor system in conceptualization Is it true, as some scientists believe, that to understand words like "spike" (in the volleyball sense) the brain has to "mentally" ...

IQWiG publishes new version of its General Methods Procedure for report production and section on meta-analyses updated / New sections on early benefit assessment The German Institute for Quality and Efficiency in Health Care (IQWiG) ...

Detailed image shows how genomes are copied For the first time, researchers at Umeå University have succeeded in showing how the DNA polymerase epsilon enzyme builds new genomes. The detailed image produced by these researchers shows how ...

The importance of standardizing drug screening studies An IRCM researcher sheds light on inconsistencies between large pharmacogenomic studies Montréal, December 2, 2013 – A bioinformatics expert at the IRCM, Benjamin Haibe-Kains, recently ...

Nanorobot for transporting drugs in the body A nanorobot is a popular term for molecules with a unique property that enables them to be programmed to carry out a specific task. In collaboration with colleagues in Italy and the USA, researchers at Aarhus University have ...

New report illustrates persistent global burden of anemia among high-risk populations (WASHINGTON, December 2, 2013) – Despite increasing efforts to diagnose and treat anemia worldwide, there remains a surprisingly large global burden of the disease, particularly ...

Researchers unlock a new means of growing intestinal stem cells Studying these cells could lead to new treatments for diseases ranging from gastrointestinal disease to diabetes CAMBRIDGE, MA -- Researchers at MIT and Brigham and Women's Hospital have shown ...

Mice can inherit learned sensitivity to a smell Trauma can scar people so indelibly that their children are affected. History provides examples of generations traumatized by war and starvation, whose children experience altered physiology. Now researchers at Yerkes ...

Forget the needle consider the haystack Uncovering hidden structures in massive data collections Advances in computer storage have created collections of data so huge that researchers often have trouble uncovering critical patterns in connections ...

Living with chronic pain: The daily struggle with a 'new self' People who suffer with chronic musculoskeletal pain face a daily struggle with their sense of self and find it difficult to prove the legitimacy of their condition. A new study, funded by the National Institute ...

Oxygen levels increase and decrease the effectiveness of anti-inflammatory therapies New research published in the Journal of Leukocyte Biology suggests that the effectiveness of anti-inflammatory glucocorticoids may be related to ...

Understanding hearing Computer models of neuronal sound processing in the brain lead to cochlear implant improvements This news release is available in German. Intact hearing is a prerequisite for learning to speak. This is why children ...

Newly discovered human peptide may become a new treatment for diabetes New research in The FASEB Journal suggests that humanin, a peptide produced by the human body, increases the metabolism of glucose in beta cells, which in turn ...

Salk scientists crack riddle of important drug target New method for determining structure of key cellular receptors could speed drug development LA JOLLA, CA---- A new approach to mapping how proteins interact with each other, developed at the Salk Institute for Biological Studies, ...