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Traumatic brain injury poses complex diagnostic, management and treatment challenges in older people

2013-05-06
Amsterdam, NL, May 6, 2013 – Each year more than 1.7 million people in the United States sustain a traumatic brain injury (TBI). The incidence of TBI in older adults poses special diagnostic, management and treatment challenges, say experts in a special collection of papers on TBI in the elderly in NeuroRehabilitation: An Interdisciplinary Journal. "As our understanding of TBI increases, it is becoming clear that its impact is not uniform across the lifespan and that the response of a young brain to a TBI is different from that of an old brain," writes Guest Editor Wayne ...

Researchers develop unique method for creating uniform nanoparticles

2013-05-06
University of Illinois researchers have developed a new way to produce highly uniform nanocrystals used for both fundamental and applied nanotechnology projects. "We have developed unique approach for the synthesis of highly uniform icosahedral nanoparticles made of platinum (Pt)," explained Hong Yang, a professor of chemical and biomolecular engineering at the University of Illinois at Urbana-Champaign. "This is important both in fundamental studies—nanoscience and nanotechnology—and in applied sciences such as high performance fuel cell catalysts." Yang's research ...

Study shows so-called cougars, sugar daddies more myth than reality

2013-05-06
DENVER (May 6, 2013) – Despite the popular image of the rich older man or woman supporting an attractive younger spouse, a new study shows those married to younger or older mates have on average lower earnings, lower cognitive abilities, are less educated and less attractive than couples of similar ages. "Hugh Hefner is an outlier," said Hani Mansour, Ph.D., an assistant professor of economics at the University of Colorado Denver who co-authored the study with Terra McKinnish, Ph.D., associate professor of economics at the University of Colorado Boulder. "Our results ...

Duke scientists build a living patch for damaged hearts

2013-05-06
DURHAM, N.C. -- Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines. The "heart patch" grown in the laboratory from human cells overcomes two major obstacles facing cell-based therapies – the patch conducts electricity at about the same speed as natural heart cells and it "squeezes" appropriately. Earlier attempts to create functional heart patches have largely been ...

Breaking the silence of suicide

2013-05-06
This news release is available in French. Montreal, May 6, 2013 – Just over a month ago, a young high school student from Halifax committed suicide after photos of her being raped were posted on the Internet. Her story wasn't just about bullying. It was also about the complex feelings her friends and family faced with her decision to take her own life. Such a reaction is common to cultures around the word. New research from Concordia University shows that, no matter where it occurs, a veil of shame and sense of taboo surround suicide. These attitudes often force those ...

New analysis suggests wind, not water, formed mound on Mars

2013-05-06
A roughly 3.5-mile high Martian mound that scientists suspect preserves evidence of a massive lake might actually have formed as a result of the Red Planet's famously dusty atmosphere, an analysis of the mound's features suggests. If correct, the research could dilute expectations that the mound holds evidence of a large body of water, which would have important implications for understanding Mars' past habitability. Researchers based at Princeton University and the California Institute of Technology suggest that the mound, known as Mount Sharp, most likely emerged as ...

Solid-state controllable light filter may protect preterm infants from disturbing light

2013-05-06
Preterm infants appear to mature better if they are shielded from most wavelengths of visible light, from violet to orange. But it has been a challenge to develop a controllable light filter for preterm incubators that can switch between blocking out all light--for sleeping--and all but red light to allows medical staff and parents to check up on the kids when they're awake. Now, in a paper accepted for publication in Applied Physics Letters, a journal of the American Institute of Physics, researchers describe a proof-of-concept mirror that switches between reflective and ...

Scaling up gyroscopes: From navigation to measuring the Earth's rotation

2013-05-06
Accurately sensing rotation is important to a variety of technologies, from today's smartphones to navigational instruments that help keep submarines, planes, and satellites on course. In a paper accepted for publication in the American Institute of Physics' journal Review of Scientific Instruments, researchers from the Technical University of Munich and New Zealand's University of Canterbury discuss what are called "large ring laser gyroscopes" that are six orders of magnitude more sensitive than gyroscopes commercially available. In part, the increased sensitivity comes ...

Research finds new cause for common lung problem

2013-05-06
New research has found that in cases of lung edema, or fluid in the lungs, not only do the lungs fail to keep water out as previously believed, but they are also allowing water to pump in. "Usually, our lungs pump fluid out of the air space, and it was previously believed that this pump mechanism just stopped when people had lung edema," said Dr. Wolfgang Kuebler, a scientist at St. Michael's Hospital. "But we've found not only do they stop pumping fluid out as they're supposed to do, they've gotten confused and are actually pumping in the reverse direction, bringing ...

Hospital surgical volume should be considered when judging value of procedures

2013-05-06
SAN DIEGO – The volume of cases performed at an institution each year has a direct effect on the outcome of surgical procedures, and should always be considered when looking at the benefits of a technique, according to a team of researchers at Henry Ford Hospital in Detroit. Those conclusions will be presented May 5 at the annual meeting of the American Urological Association in San Diego. The starting point of the study was the rapid increase in the use of surgical robots to assist in radical prostatectomy, in which the entire prostate gland and some surrounding tissue ...

Genome sequencing provides unprecedented insight into causes of pneumococcal disease

2013-05-06
Boston, MA — A new study led by researchers from Harvard School of Public Health (HSPH) and the Wellcome Trust Sanger Institute in the UK has, for the first time, used genome sequencing technology to track the changes in a bacterial population following the introduction of a vaccine. The study follows how the population of pneumococcal bacteria changed following the introduction of the 'Prevnar' conjugate polysaccharide vaccine, which substantially reduced rates of pneumococcal disease across the U.S. The work demonstrates that the technology could be used in the future ...

Media advisory: Brain cell injections may quiet epileptic seizures

2013-05-06
More than two million people in the United States suffer from epilepsies, a group of neurological disorders caused by abnormal nerve cell firing in the brain which often produce debilitating seizures. Although anti-epileptic drugs and other therapies reduce seizures in about two-thirds of patients, the remaining one-third do not respond to any form of therapy and those who take drugs can experience harmful side effects. NIH funded researchers at the University of California at San Francisco used a mouse model of epilepsy to show that transplanting new born inhibitory nerve ...

Divide and define: Clues to understanding how stem cells produce different kinds of cells

2013-05-06
ANN ARBOR—The human body contains trillions of cells, all derived from a single cell, or zygote, made by the fusion of an egg and a sperm. That single cell contains all the genetic information needed to develop into a human, and passes identical copies of that information to each new cell as it divides into the many diverse types of cells that make up a complex organism like a human being. If each cell is genetically identical, however, how does it grow to be a skin, blood, nerve, bone or other type of cell? How do stem cells read the same genetic code but divide into ...

Scientists alarmed by rapid spread of Brown Streak Disease in cassava

2013-05-06
BELLAGIO, ITALY (6 MAY 2013)— Cassava experts are reporting new outbreaks and the increased spread of Cassava Brown Streak Disease or CBSD, warning that the rapidly proliferating plant virus could cause a 50 percent drop in production of a crop that provides a significant source of food and income for 300 million Africans. The "pandemic" of CBSD now underway is particularly worrisome because agriculture experts have been looking to the otherwise resilient cassava plant—which is also used to produce starch, flour, biofuel and even beer—as the perfect crop for helping to ...

A new cost-effective genome assembly process

2013-05-06
The U.S. Department of Energy Joint Genome Institute (DOE JGI) is among the world leaders in sequencing the genomes of microbes, focusing on their potential applications in the fields of bioenergy and environment. As a national user facility, the DOE JGI is also focused on developing tools that more cost-effectively enable the assembly and analysis of the sequence that it, as well as other genome centers, generates. Despite tremendous advances in cost reduction and throughput of DNA sequencing, significant challenges remain in the process of efficiently reconstructing ...

As climate changes, boreal forests to shift north and relinquish more carbon than expected

2013-05-06
It's difficult to imagine how a degree or two of warming will affect a location. Will it rain less? What will happen to the area's vegetation? New Berkeley Lab research offers a way to envision a warmer future. It maps how Earth's myriad climates—and the ecosystems that depend on them—will move from one area to another as global temperatures rise. The approach foresees big changes for one of the planet's great carbon sponges. Boreal forests will likely shift north at a steady clip this century. Along the way, the vegetation will relinquish more trapped carbon than most ...

More hurricanes for Hawaii?

2013-05-06
News of a hurricane threat sends our hearts racing, glues us to the Internet for updates, and makes us rush to the store to stock up on staples. Hawaii, fortunately, has been largely free from these violent storms in the recent past, only two having made landfall in more than 30 years. Now a study headed by a team of scientists at the International Pacific Research Center, University of Hawaii at Manoa, shows that Hawaii could see a two-to-three-fold increase in tropical cyclones by the last quarter of this century. The study, which appears in the May 5, 2013, online ...

NIH study provides clarity on supplements for protection against blinding eye disease

2013-05-06
Adding omega-3 fatty acids did not improve a combination of nutritional supplements commonly recommended for treating age-related macular degeneration (AMD), a major cause of vision loss among older Americans, according to a study from the National Institutes of Health (NIH). The plant-derived antioxidants lutein and zeaxanthin also had no overall effect on AMD when added to the combination; however, they were safer than the related antioxidant beta-carotene, according to the study published online today in the Journal of the American Medical Association. "Millions of ...

'Look but don't touch'

2013-05-06
Improving our understanding of the human brain, gathering insights into the origin of our universe through the detection of gravitational waves, or optimizing the precision of GPS systems- all are difficult challenges to master because they require the ability to visualize highly fragile elements, which can be terminally damaged by any attempt to observe them. Now, quantum physics has provided a solution. In an article published in Nature Photonics, researchers at the Institute of Photonic Sciences (ICFO) report the observation of a highly fragile and volatile body through ...

Organic vapors affect clouds leading to previously unidentified climate cooling

2013-05-06
University of Manchester scientists, writing in the journal Nature Geoscience, have shown that natural emissions and manmade pollutants can both have an unexpected cooling effect on the world's climate by making clouds brighter. Clouds are made of water droplets, condensed on to tiny particles suspended in the air. When the air is humid enough, the particles swell into cloud droplets. It has been known for some decades that the number of these particles and their size control how bright the clouds appear from the top, controlling the efficiency with which clouds scatter ...

Improving materials that convert heat to electricity and vice-versa

2013-05-06
ANN ARBOR---Thermoelectric materials can be used to turn waste heat into electricity or to provide refrigeration without any liquid coolants, and a research team from the University of Michigan has found a way to nearly double the efficiency of a particular class of them that's made with organic semiconductors. Organic semiconductors are carbon-rich compounds that are relatively cheap, abundant, lightweight and tough. But they haven't traditionally been considered candidate thermoelectric materials because they have been inefficient in carrying out the essential heat-to-electricity ...

Protein complex may play role in preventing many forms of cancer, Stanford study shows

2013-05-06
STANFORD, Calif. - Researchers at the Stanford University School of Medicine have identified a group of proteins that are mutated in about one-fifth of all human cancers. The finding suggests that the proteins, which are members of a protein complex that affects how DNA is packaged in cells, work to suppress the development of tumors in many types of tissues. The broad reach of the effect of mutations in the complex, called BAF, rivals that of another well-known tumor suppressor called p53. It also furthers a growing notion that these so-called chromatin-regulatory complexes ...

Portable device provides rapid, accurate diagnosis of tuberculosis, other bacterial infections

2013-05-06
A handheld diagnostic device that Massachusetts General Hospital (MGH) investigators first developed to diagnose cancer has been adapted to rapidly diagnose tuberculosis (TB) and other important infectious bacteria. Two papers appearing in the journals Nature Communications and Nature Nanotechnology describe portable devices that combine microfluidic technology with nuclear magnetic resonance (NMR) to not only diagnose these important infections but also determine the presence of antibiotic-resistant bacterial strains. "Rapidly identifying the pathogen responsible for ...

Study evaluates effect of different supplements on reducing risk of progression to advanced AMD

2013-05-06
In a large, multicenter, randomized clinical trial that included persons at high risk for progression to advanced age-related macular degeneration (AMD), adding the carotenoids lutein and zeaxanthin, the omega-3 fatty acids DHA and EPA, or both to a formulation of antioxidant vitamins and minerals that has shown effectiveness in reducing risk did not further reduce risk of progression to advanced AMD, according to a study published by JAMA. The study is being released early online to coincide with its presentation at the Association for Research in Vision and Ophthalmology ...

Discovery helps show how breast cancer spreads

2013-05-06
Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread. The finding opens the door to drug treatments that prevent metastasis. It has long been known that women with denser breasts are at higher risk for breast cancer. This greater density is caused by an excess of a structural protein called collagen. "We have shown how increased collagen in the breasts could increase the chances of breast tumors spreading and becoming more ...
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