Classic signaling pathway holds the key to prostate cancer progression Approximately 1 out of every 6 American men will be diagnosed with prostate cancer, and this year alone there are expected to be nearly a quarter of a million new cases diagnosed, making prostate ...

Helping good genes win in brain cancer cells Porto Alegre, Brazil - Researchers at the Federal University of Rio Grande do Sul (UFRGS), the university hospital (Hospital de Clínicas de Porto Alegre, HCPA) and the Children's Cancer Institute (Instituto ...

Stanford and Google team up to simulate key drug receptor Roughly 40 percent of all medications act on cells' G protein-coupled receptors (GPCRs). One of these receptors, beta 2 adrenergic receptor site (B2AR), naturally transforms between two base configurations; knowing ...

UT Southwestern neuroscience researchers identify gene involved in response to cocaine DALLAS – Dec. 19, 2013 – UT Southwestern neuroscience researchers have identified a gene that controls the response to cocaine by comparing closely related ...

ASU researchers develop new device to help image key proteins at room temperature TEMPE, Ariz. – A group of researchers from Arizona State University are part of a larger team reporting a major advance in the study of human proteins that could open up new avenues ...

91 new species described by California Academy Of Sciences in 2013 SAN FRANCISCO (December 20, 2013) — In 2013, researchers at the California Academy of Sciences discovered 91 new plant and animal species and two new genera, enriching our understanding ...

JCI early table of contents for Dec. 20, 2013 Fungal surface protein promotes host cell Opportunistic infection of individuals on immunosuppressive therapy are a major problem for patient outcome, despite current prophylactic strategies. While the ability ...

Fungal surface protein promotes host cell Opportunistic infection of individuals on immunosuppressive therapy are a major problem for patient outcome, despite current prophylactic strategies. While the ability to prevent infection with well-characterized ...

Angiogenic factor secretion by melanocytes associated with pigmentation leve The decreased vision loss that accompanies age-related macular degeneration (AMD) is associated with abnormal blood vessel growth in the eye. Frequencies of AMD development are ...

Nonsense suppression drug restores function in a mouse model of aniridia Congenital aniridia is a progressive disease that is associated with improper development of eye structures as well as abnormalities in the brain and pancreas. A variety of nonsense ...

Dysfunctional TGF-beta signaling contributes to Loeys-Dietz syndrome-associated aortic aneurysm Patients with the connective tissue disorder Loeys-Dietz syndrome (LDS) are at high risk for aortic aneurysm. LDS results in the presence of missense mutations ...

Evaluation of mangafodipir treatment for oxaliplatin-associated neuropathy An unfortunate side effect of the platinum-chemotherapy drug oxaliplatin is the development of neurotoxicity, which can adversely affect a patient's quality of life; therefore, ...

New research offers hope for vaccine and therapies for deadly infections LA BioMed researcher leads team that finds antibodies to protect against mucormycosis LOS ANGELES – (Dec. 20, 2013) – Mucormycosis ...

UBC-VCH scientists use drug to repair rare birth defect Success in mouse model is first instance of drug reversing a congenital deformity University of British Columbia and Vancouver Coastal Health scientists have developed a potential cure for a rare eye disease, ...

Enlisting cells' protein recycling machinery to regulate plant products New molecular tools for controlling production of compounds important for flavors, human health, and biofuels UPTON, NY--Scientists at the U.S. Department of Energy's Brookhaven ...

New mechanism that permits selective capture of microRNAs in nanovesicles that shuttle between cells The study presents the first description of a set of related nuceleotide sequences essential for the role of these small molecules in ...

More mentions in the FT linked to greater popularity of stocks A 6-year study of the Financial Times has found that the more frequently a company is mentioned in the newspaper in the morning, the greater the volume of shares traded in that company during the ...

Efforts to curb climate change require greater emphasis on livestock CORVALLIS, Ore. – While climate change negotiators struggle to agree on ways to reduce carbon dioxide (CO2) emissions, they have paid inadequate attention to other greenhouse gases associated ...

Birth of black hole kills the radio star Research clears telescope, disproves long-held theory Astronomers led by a Curtin University researcher have discovered a new population of exploding stars that "switch off" their radio transmissions before collapsing ...

An earthquake or a snow avalanche has its own shape However, it is crucial what one observes – paper fracture or the avalanching of snow. The results were just published in the Nature Communications journal. Avalanches of snow or earthquakes can be described in other ...

Smooth or grainy? A SISSA paper reviews research on the grain of space-time Smooth" or grainy? Is space-time continuous or is it made up of very fine (10-35 metres on the "Planck scale") but discrete grains, if we look at it very ...

IRB develops ChroGPS, a new generation visual browser of the epigenome This is a software application that provides easily interpretable maps from which to analyse and understand the immense volume of epigenetic and genetic ...

Birth control at the zoo Vets meet the elusive goal of hippo castration Common hippopotami (Hippopotamus amphibius) are vulnerable to extinction in the wild, but reproduce extremely well under captive breeding conditions. Females ...

Breaking down cancer's defense mechanisms A possible new method for treating pancreatic cancer which enables the body's immune system to attack and kill cancer cells has been developed by researchers. The method uses a drug which breaks down the ...

A gluttonous plant reveals how its cellular power plant devours foreign DNA Amborella trichopoda, a sprawling shrub that grows on just a single island in the remote South Pacific, is the only plant in its family and genus. It is also one of the oldest flowering ...