Youth who had a schoolmate die by suicide are significantly more likely to consider or attempt suicide, according to a study in published in CMAJ (Canadian Medical Association Journal). This effect can last 2 years or more, which has implications for strategies following schoolmate suicides. "We found that exposure to suicide predicts suicidality," writes senior author Dr. Ian Colman, Canada Research Chair in Mental Health Epidemiology and Assistant Professor, University of Ottawa, with lead author Sonja Swanson, from Harvard School of Public Health, Boston. "This was ...

ATS 2013, PHILADELPHIA─Treatment with an Alpha-1 proteinase inhibitor (A1-PI), a naturally occurring protein that protects lung tissue from breakdown and protects the lung's elasticity, is effective in slowing the progression of emphysema in patients with Alpha-1 antitrypsin deficiency (AATD), a life-threatening genetic disorder, according to a new study presented at the 2013 American Thoracic Society International Conference. The study showed the efficacy of A1-PIin preventing the loss of lung tissue as measured by computed tomography (CT) scan lung density at ...

Durham, NC — Biologists have known for a long time that some creatures evolve more quickly than others. Exactly why isn't well understood, particularly for plants. But it may be that height plays a role, says Robert Lanfear of Australian National University and the U. S. National Evolutionary Synthesis Center. In a study to be published 21 May in the journal Nature Communications, Lanfear and colleagues report that shorter plants have faster-changing genomes. Drawing from a database of global patterns in plant height for more than 20,000 species, the researchers estimated ...

The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester, potentially providing a simple way to foretell depression in the weeks after giving birth, and an opportunity to intervene before symptoms become debilitating. The findings of the small study involving 52 pregnant women are described online in the journal Molecular Psychiatry. "Postpartum depression can be harmful to both mother and child," says study leader Zachary Kaminsky, Ph.D., ...

Children who have suffered maltreatment are 36% more likely to be obese in adulthood compared to non-maltreated children, according to a new study by King's College London. The authors estimate that the prevention or effective treatment of 7 cases of child maltreatment could avoid 1 case of adult obesity. The findings come from the combined analysis of data from 190,285 individuals from 41 studies worldwide, published this week in Molecular Psychiatry. Severe childhood maltreatment (physical, sexual or emotional abuse or neglect) affects approximately 1 in 5 children ...

Rapid climate change during the Middle Stone Age, between 80,000 and 40,000 years ago, during the Middle Stone Age, sparked surges in cultural innovation in early modern human populations, according to new research. The research, published this month in Nature Communications, was conducted by a team of scientists from Cardiff University's School of Earth and Ocean Sciences, the Natural History Museum in London and the University of Barcelona. The scientists studied a marine sediment core off the coast of South Africa and reconstructed terrestrial climate variability ...

VIDEO: Dr. William Jacobs, Jr. has determined that vitamin C kills drug-resistant tuberculosis (TB) bacteria in laboratory culture. The paper was published online May 21, 2013 in Nature Communications. Dr. Jacobs... Click here for more information. May 21, 2013 — (Bronx, NY) — In a striking, unexpected discovery, researchers at Albert Einstein College of Medicine of Yeshiva University have determined that vitamin C kills drug-resistant tuberculosis (TB) bacteria in laboratory ...

Nowadays, the most diverse species of crocodile are found in northern South America and Southeast Asia: As many as six species of alligator and four true crocodiles exist, although no more than two or three ever live alongside one another at the same time. It was a different story nine to about five million years ago, however, when a total of 14 different crocodile species existed and at least seven of them occupied the same area at the same time, as an international team headed by paleontologists Marcelo Sánchez and Torsten Scheyer from the University of Zurich is now ...

Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes. The breakthrough study, conducted by Sean Humphrey and Professor David James from Sydney's Garvan Institute of Medical Research, is now published in the early online edition of the prestigious journal Cell Metabolism. First discovered in 1921, the insulin hormone plays a very important role in the body because it helps us lower blood sugar after a meal, by enabling the movement ...

Philadelphia, Pa. (May 21, 2013) – Arachnoid cysts are a common type of brain lesion that is usually harmless, but with a risk of rupture or bleeding. A new study identifies risk factors for rupture or bleeding in children with "incidentally" detected arachnoid cysts, reports the May issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. Risk is higher for children with larger cysts and a recent history of even mild head trauma, according to the report ...

The warning images Brussels proposes to include on tobacco packages in order to reduce consumption do not make the desired impact on smokers because they only find some of them really unpleasant. So, if the European Commission wants to improve the efficacy of its anti-smoking campaigns, it should produce a new set of images that make a stronger emotional impact. These are some of the conclusions of research conducted in the Department of Personality, Evaluation and Psychological Treatment at the University of Granada by Miguel Ángel Muñoz, Luis Ciria y Jaime Vila Castelar, ...

Scientists from Nanyang Technological University (NTU) and Lund University, Sweden, have bioengineered a novel molecule which has been proven to successfully kill tumour cells. This molecule is based on a natural protein present in human breast milk, which has been found to have strong and wide-ranging tumour killing properties when bound to certain lipids. Lipids are organic molecules like amino acids and carbohydrates, made up of carbon and hydrogen, and help to store energy and to form biological membranes. The protein-lipid molecule complex, is known as HAMLET, ...

Regardless of pain, social class or age, a woman is more likely to be prescribed pain-relieving drugs. A study published in Gaceta Sanitaria (Spanish health scientific journal) affirms that this phenomenon is influenced by socioeconomic inequality between genders in the Autonomous Community in which the patient resides. In 1999, a researcher at the University of Harvard, Ishiro Kawachi, observed that in the states of the USA with a larger proportion of women with a high social class, mortality in both genders was lower. Inspired by Kawachi's studies, experts at the ...

The level of immunity to the recently circulating H7N9 influenza virus in an urban and rural population in Vietnam is very low, according to the first population level study to examine human immunity to the virus, which was previously only found in birds. The findings have implications for planning the public health response to this pandemic threat. The study used a new, high throughput method that allows blood samples to be analysed for antibodies to multiple human and animal influenza viruses at the same time and is easier to standardise than previous techniques. However, ...

BOSTON (May 21, 2013) – Prostaglandin analogues (PGAs), drugs which lower intraocular pressure, are often the first line of treatment for people with glaucoma, but their use is not without risks. PGAs have long been associated with blurred vision, dryness, changes in eye color and other side effects. Now a new study has found that these drugs also cause upper and lower eyelid drooping and other issues that can interfere with vision. The findings are described in PLOS ONE. Researchers from the Massachusetts Eye and Ear performed multivariable analysis accounting for age, ...

Most elite athletes consider doping substances "are effective" in improving performance, while recognising that they constitute cheating, can endanger health and entail the obvious risk of sanction. At the same time, the reasons why athletes start to take doping substances are to achieve athletic success, improve performance, for financial gain, to improve recovery and to prevent nutritional deficiencies, as well as "because other athletes also use them". These are some of the conclusions of a study conducted by researchers from the Department of Physical and Sports Education ...

Researchers at Emory University have identified a protein that stimulates a pair of "orphan receptors" found in the brain, solving a long-standing biological puzzle and possibly leading to future treatments for neurological diseases. The results are published in the Proceedings of the National Academy of Sciences, Early Edition. The human genome is littered with orphans: proteins that look like they will bind and respond to a hormone or a brain chemical, based on the similarity of their sequences to other proteins. However, scientists haven't figured out what each orphan's ...

Knee replacement surgery is a very common procedure. However, it does not always resolve function or pain in all the recipients of new knees. A study by Robert Barrack, MD and his colleagues from the Washington University School of Medicine wanted to determine if any socioeconomic factors were associated with less successful outcomes of knee replacement surgery. Their study, which appears in Clinical Orthopaedics and Related Research®, published by Springer, found that lower-income individuals reported higher levels of dissatisfaction and poorer function than those with ...

Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older people experiencing memory impairment. Now a team headed by Prof. Gil Ast and Dr. Ron Bochner of Tel Aviv University's Department of Human Molecular Genetics have discovered that the same supplement improves the functioning of genes involved in degenerative brain disorders, including Parkinson's disease and Familial Dysautonomia (FD). In FD, a rare genetic ...

CAMBRIDGE, MA -- Over the past few decades, scientists have developed many devices that can reopen clogged arteries, including angioplasty balloons and metallic stents. While generally effective, each of these treatments has drawbacks, including the risk of side effects. A new study from MIT analyzes the potential usefulness of a new treatment that combines the benefits of angioplasty balloons and drug-releasing stents, but may pose fewer risks. With this new approach, a balloon is inflated in the artery for only a brief period, during which it releases a drug that prevents ...

ROCHESTER, Minn. — Positively charged gold nanoparticles are usually toxic to cells, but cancer cells somehow manage to avoid nanoparticle toxicity. Mayo Clinic researchers found out why, and determined how to make the nanoparticles effective against ovarian cancer cells. The discovery is detailed in the current online issue of the Journal of Biological Chemistry. "This study identifies a novel mechanism that protects ovarian cancer cells by preventing the cell death or apoptosis which should occur when they encounter positively charged nanoparticles," say the senior authors ...

HOUSTON -- (May 21, 2013) -- Rice University scientists have unveiled a robust new method for arranging metal nanoparticles in geometric patterns that can act as optical processors that transform incoming light signals into output of a different color. The breakthrough by a team of theoretical and applied physicists and engineers at Rice's Laboratory for Nanophotonics (LANP) is described this week in the Proceedings of the National Academy of Sciences. Rice's team used the method to create an optical device in which incoming light could be directly controlled with light ...

LOUISVILLE, Ky. – Grapefruits have long been known for their health benefits, and the subtropical fruit may revolutionize how medical therapies like anti-cancer drugs are delivered to specific tumor cells. University of Louisville researchers have uncovered how to create nanoparticles using natural lipids derived from grapefruit, and have discovered how to use them as drug delivery vehicles. UofL scientists Huang-Ge Zhang, D.V.M., Ph.D., Qilong Wang, Ph.D., and their team today (May 21, 2013), published their findings in Nature Communications. "These nanoparticles, ...

Scientists discovered a new enigmatic species of ant coming from the Philippines. Cardiocondyla pirata or the pirate ant engages the imagination with a bizarre pigmentation pattern that has no equivalent worldwide. The female castes in the colonies of these species can be recognized by a distinctive dark stripe across the eyes that resembles a pirate eye patch, which inspired the authors to choose the name of the species. The study was published in the open access journal Zookeys. "On a collection trip to the Philippines we looked for different species of the genus ...

ANN ARBOR—You're standing near an airport luggage carousel and your bag emerges on the conveyor belt, prompting you to spring into action. How does your brain make the shift from passively waiting to taking action when your bag appears? A new study from investigators at the University of Michigan and Eli Lilly may reveal the brain's "switch" for new behavior. They measured levels of a neurotransmitter called acetylcholine, which is involved in attention and memory, while rats monitored a screen for a signal. At the end of each trial, the rat had to indicate if a signal ...