First major study of suicide motivations to advance prevention
2013-06-13
A University of British Columbia study sheds important new light on why people attempt suicide and provides the first scientifically tested measure for evaluating the motivations for suicide.
Published in the official journal of the American Association of Suicidology, the work gives doctors and researchers important new resources to advance suicide prevention, improve treatments, and reduce the likelihood of further attempts.
"Knowing why someone attempted suicide is crucial – it tells us how to best help them recover," says Prof. David Klonsky, UBC Dept. of Psychology. ...
World population could be nearly 11 billion by 2100, UW research shows
2013-06-13
A new statistical analysis shows the world population could reach nearly 11 billion by the end of the century, according to a United Nations report issued June 13. That's about 800 million, or about 8 percent, more than the previous projection of 10.1 billion, issued in 2011.
The projected rise is mostly due to fertility in Africa, where the U.N. had expected birth rates to decline more quickly than they have.
"The fertility decline in Africa has slowed down or stalled to a larger extent than we previously predicted, and as a result the African population will go ...
50 percent of rheumatoid arthritis patients discontinue medication within the first 2 years
2013-06-13
Madrid, Spain, 13 June 2013: Data presented at EULAR 2013, the Annual Congress of the European League Against Rheumatism, show that up to one-third of rheumatoid arthritis (RA) patients discontinue or change therapy within the first year of treatment.
Loss of efficacy was the most common reason given (35.8%), followed by safety (20.1%), physician or patient preference (27.8% and 17.9%, respectively) and access to treatment (9.0%). Rates and rationale for treatment discontinuation were similar for both tumour necrosis factor inhibitors (TNFi) and non-TNFi biologics.
RA ...
Childbirth increases risk of ACPA-negative rheumatoid arthritis
2013-06-13
Madrid, Spain, 13 June 2013: Epidemiological data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that pregnancy carried to childbirth (parity) increases the risk of ACPA-negative* rheumatoid arthritis (RA).
The increased risk was demonstrated in women aged 18-44 who have had a child (2.1, 95% CI 1.4-3.2), but not in older women, and was more pronounced among those women with delivery during the first year of symptoms.
RA is an autoimmune disease characterised by inflammation of the joints and tendons. As a ...
Canakinumab allows discontinuation of corticosteroids in patients with SJIA
2013-06-13
Madrid, Spain, 13 June 2013: Study findings first presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate the efficacy of canakinumab at tapering corticosteroid (CS) use in patients with SJIA.
Successful CS tapering was achieved within 20 weeks in almost half of patients (44.5%, p END ...
Depression indicators predict work disabilty more than disease activity or response to therapy
2013-06-13
Madrid, Spain, 13 June 2013: Data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that indicators of depression are stronger predictors of work disability in early arthritis than disease activity or response to therapy.
The study showed that in a multivariable analysis none of the arthritis activity measures or cardiovascular, metabolic or pulmonary diseases investigated were associated with early retirement, yet a single depression statement "having little pleasure or interest in doing things most of the days ...
'Tailing' spiny lobster larvae to protect them
2013-06-13
MIAMI – June 13, 2013 – The commercial value of spiny lobster (Panulirus argus) in the Caribbean reaches $1 billion annually, thus making it one of the most valuable fisheries in the region. In a new study of this iconic species, Ph.D. candidate Andrew Kough and Dr. Claire Paris of the Biophysical Interactions Lab at the University of Miami Rosenstiel School of Marine & Atmospheric Science, in collaboration with Dr. Mark Butler from Old Dominion University, studied the larval dispersal of this species in the Caribbean. The goal of the study was to describe the sources, ...
Literacy, not income, key to improving public health in India
2013-06-13
Pro-market policies for developing countries have long been based on the belief that increasing average income is key to improving public health and societal well-being.
But new research on India published in the journal Social Science and Medicine shows that literacy - a non-income good - has a greater impact on public health in India.
While the researchers, based at Cambridge's Department of Sociology, accept it is broadly true that "wealthier is healthier" across the roughly 500 districts in India's 'major states', accounting for 95% of the total population, they ...
Spot-welding graphene nanoribbons atom by atom
2013-06-13
Scientists at Aalto University, Finland and Utrecht University, the Netherlands have created single atom contacts between gold and graphene nanoribbons.
In their article published in Nature Communications, the research team demonstrates how to make electrical contacts with single chemical bonds to graphene nanoribbons. Graphene is a single layer of carbon atoms arranged in a honeycomb lattice. It is anticipated to be a revolutionising material for future electronics.
Graphene transistors functioning at room temperature require working at the size scale of less than ...
After an ACL tear: Research opens door to new treatments to improve recovery for athletes
2013-06-13
ANN ARBOR, Mich. — Striking the likes of Chicago Bulls' Derrick Rose, L.A. Lakers' Kobe Bryant and Detroit Tigers' Victor Martinez, tears in the anterior cruciate ligament (ACL) are one of the most rampant and serious knee injuries among athletes.
Now, researchers from the University of Michigan Health System have identified a new drug target that may prevent one of the most dreaded consequences of an ACL tear –the weakening or loss of muscle tissue (muscle atrophy) that can be a career-killer in sports and ultimately develop into osteoarthritis.
A hormone called myostatin ...
Researchers gain new molecular-level understanding of the brain's recovery after stroke
2013-06-13
DETROIT – A specific MicroRNA, a short set of RNA (ribonuclease) sequences, naturally packaged into minute (50 nanometers) lipid containers called exosomes, are released by stem cells after a stroke and contribute to better neurological recovery according to a new animal study by Henry Ford Hospital researchers.
The important role of a specific microRNA transferred from stem cells to brain cells via the exosomes to enhance functional recovery after a stroke was shown in lab rats. This study provides fundamental new insight into how stem cells affect injured tissue and ...
Light-carved 'nano-volcanoes' hold promise for drug delivery
2013-06-13
Researchers from North Carolina State University have developed a method for creating "nano-volcanoes" by shining various colors of light through a nanoscale "crystal ball" made of a synthetic polymer. These nano-volcanoes can store precise amounts of other materials and hold promise for new drug-delivery technologies.
The researchers create the nano-volcanoes by placing spherical, transparent polymer nanoparticles directly onto the flat surface of a thin film. They then shine ultraviolet light through the transparent sphere, which scatters the light and creates a pattern ...
DNA brings materials to life
2013-06-13
A colloid is a substance spread out evenly inside another substance. Everyday examples include milk, styrofoam, hair sprays, paints, shaving foam, gels and even dust, mud and fog. One of the most interesting properties of colloids is their ability to self-assemble – to aggregate spontaneously into well-defined structures, driven by nothing but local interactions between the colloid's particles. Self-assembly has been of major interest in industry, since controlling it would open up a whole host of new technologies, such as smart drug-delivery patches or novel paints that ...
DNA sequencing uncovers secrets of white cliffs of Dover
2013-06-13
The University of Exeter recently contributed to a major international project to sequence the genome of Emiliania huxleyi, the microscopic plankton species whose chalky skeletons form the iconic white cliffs of Dover. The results of the project are published this week in the journal Nature.
Emiliania huxleyi is one of the most abundant marine phytoplankton species and is a key player in the process of CO2 exchange between the atmosphere and the ocean. In some marine systems 20% of the total carbon is fixed by E. huxleyi. This microscopic alga has influenced the global ...
UF study finds brain-imaging technique can help diagnose movement disorders
2013-06-13
GAINESVILLE, Fla. — A new University of Florida study suggests a promising brain-imaging technique has the potential to improve diagnoses for the millions of people with movement disorders such as Parkinson's disease.
Utilizing the diffusion tensor imaging technique, as it is known, could allow clinicians to assess people earlier, leading to improved treatment interventions and therapies for patients.
The three-year study looked at 72 patients, each with a clinically defined movement disorder diagnosis. Using a technique called diffusion tensor imaging, the researchers ...
Gene offers an athlete's heart without the exercise
2013-06-13
Researchers at Case Western Reserve University have found that a single gene poses a double threat to disease: Not only does it inhibit the growth and spread of breast tumors, but it also makes hearts healthier.
In 2012, medical school researchers discovered the suppressive effects of the gene HEXIM1 on breast cancer in mouse models. Now they have demonstrated that it also enhances the number and density of blood vessels in the heart – a sure sign of cardiac fitness.
Scientists re-expressed the HEXIM1 gene in the adult mouse heart and found that the hearts grew heavier ...
Study points to role of nervous system in arthritis
2013-06-13
Arthritis is a debilitating disorder affecting one in 10 Canadians, with pain caused by inflammation and damage to joints.
Yet the condition is poorly managed in most patients, since adequate treatments are lacking – and the therapies that do exist to ease arthritis pain often cause serious side effects, particularly when used long-term. Any hope for developing more-effective treatments for arthritis relies on understanding the processes driving this condition.
A new study in the Journal of Neuroscience by researchers at McGill University adds to a growing body of ...
A peptide to protect brain function
2013-06-13
A structure called "the microtubule network" is a crucial part of our nervous system. It acts as a transportation system within nerve cells, carrying essential proteins and enabling cell-to-cell communications. But in neurodegenerative diseases like Alzheimer's, ALS, and Parkinson's, this network breaks down, hindering motor abilities and cognitive function.
Now Prof. Illana Gozes of Tel Aviv University's Sackler Faculty of Medicine has developed a new peptide in her lab, called NAP or Davunetide, that has the capacity to both protect and restore microtubule function. ...
Helping to restore balance after inner ear disorder
2013-06-13
Many disorders of the inner hear which affect both hearing and balance can be hugely debilitating and are currently largely incurable. Cochlear implants have been used for many years to replace lost hearing resulting from inner ear damage. However, to date, there has not been an analogous treatment for balance disorders resulting from inner ear disease. One potential new treatment is an implantable vestibular prosthesis which would directly activate the vestibular nerve by electrical stimulation. This prosthetic treatment is tested in a new study by Christopher Phillips ...
US forest management policy must evolve to meet bioenergy targets
2013-06-13
CHAMPAIGN, Ill. — In order to keep pace with the burgeoning demand for renewable energy, forest management policy in the U.S. must change to address environmental sustainability issues, according to an article by a University of Illinois expert in bioenergy law.
Unless the forestry sector can tailor sustainable forest management policies specifically to forest-to-energy feedstocks, its role in helping the country broaden its energy portfolio – and by extension, meeting ambitious bioenergy targets – may be limited in large part because of uncertainty about whether existing ...
No good substitute for race in college admissions: Research
2013-06-13
COLLEGE PARK, Md. – As the U.S. Supreme Court decides in a case involving racial preferences in higher education admissions (Fisher v. Texas), new University of Maryland-led research finds that socioeconomic diversity is no replacement for a direct consideration of race, as some have suggested. Still the research finds that a mix of students from differing socio-economic backgrounds has benefits.
The peer-reviewed study appears in the June issue of the "American Educational Research Journal." It evaluates the use of "socio-economic status" as a racially blind way to build ...
Yale researchers unravel genetics of dyslexia and language impairment
2013-06-13
A new study of the genetic origins of dyslexia and other learning disabilities could allow for earlier diagnoses and more successful interventions, according to researchers at Yale School of Medicine. Many students now are not diagnosed until high school, at which point treatments are less effective.
The study is published online and in the July print issue of the American Journal of Human Genetics. Senior author Jeffrey R. Gruen, M.D., professor of pediatrics, genetics, and investigative medicine at Yale, and colleagues analyzed data from more than 10,000 children born ...
Men with restless legs syndrome may be at higher risk of early death
2013-06-13
MINNEAPOLIS – Men who experience restless legs syndrome (RLS) may have a higher risk of dying earlier, according to research that appears in the June 12, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. The disorder is characterized by an irresistible urge to move the legs and often causes leg sensations of burning, creeping, and tugging, which are usually worse at night.
"RLS affects five to 10 percent of adults across the country," said study author Xiang Gao, MD, PhD, with Harvard School of Public Health, Harvard Medical School ...
Biomarkers may be key to discovery of successful initial treatment of depression
2013-06-13
In a National Institutes of Health (NIH) funded clinical trial, researchers at Emory have discovered that specific patterns of brain activity may indicate whether a depressed patient will or will not respond to treatment with medication or psychotherapy. The study was published June 12, 2013, in JAMA Psychiatry Online First.
The choice of medication versus psychotherapy is often based on the preference of the patient or clinician, rather than objective factors. On average, 35-40 percent of patients get well with whatever treatment they start with.
"To be ill with ...
Infants express non-verbal sympathy for others in distress
2013-06-13
VIDEO:
This movie file shows the attacker chasing the victim and hit it seven times, violently attacking and crushing the victim at the end of the movie.
Click here for more information.
Infants as young as ten months old express sympathy for others in distress in non-verbal ways, according to research published June 12 in the open access journal PLOS ONE by Yasuhiro Kanakogi and colleagues from Kyoto University and Toyohashi University of Technology, Japan.
Infants at this ...
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