Mutations in novel tumor suppressor gene associated with early onset breast cancer RINT1 gene variants also may play role in other cancers An international team of scientists has identified an association between heritable, rare mutations in the RINT1 gene ...

BROCA sequencing approach evaluates all 24 genes implicated in breast cancer Explains occurrence of breast cancer in women with normal BRCA genes, scientists report at ASHG 2013 Since 1994, many thousands of women with breast cancer from families severely ...

Gene variants in immune system pathways are correlated with composition of microbes of human body These genes are significantly enriched in inflammatory and immune pathways Human genes in immunity-related pathways are likely associated with the composition ...

UMass Amherst researcher quantifies the effectiveness of video ads Perhaps the largest-ever scientific study of the effectiveness of video ads addresses a key question for advertisers who want to capitalize on online video, the 'killer app' of ...

Barrier to HIV cure bigger than previously thought New Cell paper suggests the latent reservoir barrier in HIV patients could be 60 times larger than previous estimates VIDEO: ...

That allergic reaction to bee stings? It's meant to protect you Allergic reactions to bee stings can be damaging or even deadly, but new evidence from two independent studies of mice reported in the Cell Press journal Immunity on October 24th suggest that the immune response ...

Samurai sword protein makes strategic cuts in cell skeletons Carefully placed and timed cuts give cell skeletons the best pattern for a particular function Just as our bodies have skeletons, so do our cells. They're equally indispensible in both cases. Without ...

Curing HIV/AIDS gets tougher: Study shows far more 'hidden' and potentially active virus than once thought Discovery of a larger than expected latent reservoir of HIV confounds 'shock and kill' cure strategy Just when some scientists were becoming more hopeful about ...

Researchers design global HIV vaccine that shows promise in monkeys Preclinical study provides strong rationale for clinical trials BOSTON -- The considerable diversity of HIV worldwide represents a critical challenge for designing an effective ...

Genetic mutation provides clues to battling childhood obesity As the number of children battling obesity continues to grow, researchers are racing to identify causes and possible interventions. Now, a new paper publishing October 24 in the journal Cell identifies a possible ...

Bee sting allergy could be a defense response gone haywire, Stanford scientists say STANFORD, Calif. — For most people, a bee sting causes temporary pain and discomfort, but for those with a bee venom allergy, the consequences can be devastating: ...

Researchers identify gene variant that raises risk for colorectal cancer from eating processed meat Discovery sets first step towards identification of genetic variants linked to carcinogenic risk from diet and nutrition A common genetic variant that affects ...

Reservoir of hidden HIV larger than previously thought New findings put spotlight on need for new drugs to target HIV proviruses In the fight to cure human immunodeficiency virus (HIV), researchers have been dealt a blow. A new study by Howard Hughes Medical Institute ...

Researchers apply brainpower to understanding neural stem cell differentiation How do humans and other mammals get so brainy? USC researcher Wange Lu, PhD, and his colleagues shed new light on this question in a paper that will be published in Cell ...

Novel genetic mutations cause low metabolic rate and obesity Researchers believe the gene could be a useful therapeutic target for treating obesity and type 2 diabetes Researchers from the University of Cambridge have discovered a novel genetic cause of severe ...

For fish and rice to thrive in Yolo Bypass, 'just add water' From a fish-eye view, rice fields in California's Yolo Bypass provide an all-you-can-eat bug buffet for juvenile salmon seeking nourishment on their journey to the sea. That's according ...

Physicists decode decision circuit of cancer metastasis Rice U. research reveals 3-way genetic switch for cancer metastasis Cancer researchers from Rice University have deciphered the operating principles of a genetic switch that cancer cells use to decide when to metastasize and ...

Study shows no increased risk for heart attacks among HIV-positive patients with high CD4 cell count Healthy HIV-positive subjects have same heart-attack risk as general population OAKLAND, Calif., October 24, 2013 — Patients who are HIV-positive and have high CD4 cell ...

Climate change and coevolution: We've done the math A rule of thumb to help calculate the likely effect of climate change where species interact When scientists attempt to understand how climate change might reshape our environment, they must grapple ...

Study by researchers at Saarland University demonstrates preventive effect of sterols in Alzheimer's This news release is available in German. "Plant sterols are present in various combinations in nuts, seeds and plant oils. As plant sterols are the equivalents of animal cholesterol, ...

How are children affected by maternal anxiety and depression? Maternal symptoms of anxiety and depression increased the risk of emotional and disruptive problem behaviors in children as early as 18 months of age, according to new research findings from the ...

Bigger, better, faster 3D structure reveals protein's Swiss-army knife strategy The molecular machine that makes essential components of ribosomes – the cell's protein factories – is like a Swiss-army knife, researchers at the European Molecular Biology Laboratory ...

Deadly gaps persist in new drug development for neglected diseases New study shows that, despite some progress, only 4 percent of new drugs and vaccines approved 2000-2011 were for neglected diseases, and a 'fatal imbalance' remains in R&D for many neglected ...

Coyote more likely to make a meal out of moose than we thought: Study This news release is available in French. It has long been believed that coyotes were incapable of taking down an adult moose, but researchers have recently discovered ...

Better sex in return for good gifts A male spider that gives its selected female a nuptial gift is allowed to mate with her for a longer period of time and provide more sperm than a male that fails to come with a gift Culinary gifts The male's nuptial gift consists ...