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Frontiers news briefs: 27 June

2013-06-28
Frontiers in Microbiology The genome of the endophytic bacterium H. frisingense GSF30T identifies diverse strategies in the Herbaspirillum genus to interact with plants Microbes whose habitat is inside other organisms, such as so-called "endophytic" bacteria that live inside plants, have evolved genes that enable them to overcome their host's defensive mechanisms. But once they have entered the host tissue, such microbes may actually benefit their host, for example, by activating genes that capture atmospheric nitrogen and turn it into natural fertilizer to promote ...

Study appears to overturn prevailing view of how the brain is wired

2013-06-28
NEW YORK, NY (June 27, 2013) — A series of studies conducted by Randy Bruno, PhD, and Christine Constantinople, PhD, of Columbia University's Department of Neuroscience, topples convention by showing that sensory information travels to two places at once: not only to the brain's mid-layer (where most axons lead), but also directly to its deeper layers. The study appears in the June 28, 2013, edition of the journal Science. For decades, scientists have thought that sensory information is relayed from the skin, eyes, and ears to the thalamus and then processed in the ...

Humans play role in Australia's 'angry' hot summer

2013-06-28
Human influences through global warming are likely to have played a role in Australia's recent "angry" hot summer, the hottest in Australia's observational record, new research has found. The research led by the University of Melbourne, has shown that global warming increased the chances of Australians experiencing record hot summers such as the summer of 2013, by more than five times. Lead author, Dr Sophie Lewis from the University of Melbourne and the ARC Centre of Excellence for Climate Systems Science said the study showed it was possible to say with more than ...

Resistance gene found against Ug99 wheat stem rust pathogen

2013-06-28
MANHATTAN, Kan. -- The world's food supply got a little more plentiful thanks to a scientific breakthrough. Eduard Akhunov, associate professor of plant pathology at Kansas State University, and his colleague, Jorge Dubcovsky from the University of California-Davis, led a research project that identified a gene that gives wheat plants resistance to one of the most deadly races of the wheat stem rust pathogen -- called Ug99 -- that was first discovered in Uganda in 1999. The discovery may help scientists develop new wheat varieties and strategies that protect the world's ...

New low-cost, transparent electrodes

2013-06-28
WASHINGTON D.C., June 27, 2013 -- Indium tin oxide (ITO) has become a standard material in light-emitting diodes, flat panel plasma displays, electronic ink and other applications because of its high performance, moisture resistance, and capacity for being finely etched. But indium is also rare and expensive, and it requires a costly deposition process to make opto-electronic devices and makes for a brittle electrode. Replacing indium as the default material in transparent electrodes is a high priority for the electronics industry. Now, in a paper appearing in APL Materials, ...

After Great Dane success, cancer doc eyes brain tumors

2013-06-28
Michael Graner, PhD, is a CU Cancer Center investigator and associate professor of neurosurgery at the CU School of Medicine. So when his 12-year-old Great Dane got sick, he knew what to do. "We got Star from the Mid-Atlantic Great Dane Rescue," Graner says. "She got her name because she was always smiling, like a movie star waiting for photos. She'd already been to so many shelters, we didn't want to change her name again and so we kept it." At 12, after many years with the Graners, Star had already reached about double the average lifespan for the breed. When she ...

Exotic alloys for potential energy applications

2013-06-28
WASHINGTON D.C., June 28, 2013 -- The search for thermoelectrics, exotic materials that convert heat directly into electricity, has received a boost from researchers at the California Institute of Technology and the University of Tokyo, who have found the best way to identify them. In the new open-access journal APL Materials, the team shows that a relatively simple technique called the "rigid band approximation" can predict a material's properties more accurately than a competing, more complicated method. "The rigid band approach still supplies the simple, predictive ...

Scientists discover thriving colonies of microbes in ocean 'plastisphere'

2013-06-28
Scientists have discovered a diverse multitude of microbes colonizing and thriving on flecks of plastic that have polluted the oceans—a vast new human-made flotilla of microbial communities that they have dubbed the "plastisphere." In a study recently published online in Environmental Science & Technology, the scientists say the plastisphere represents a novel ecological habitat in the ocean and raises a host of questions: How will it change environmental conditions for marine microbes, favoring some that compete with others? How will it change the overall ocean ecosystem ...

Why is pulmonary hypertension at high altitude so common and dangerous?

2013-06-28
New Rochelle, NY, June 26, 2013—Everyone who climbs to high altitude will develop pulmonary hypertension, a temporary constriction of blood vessels that results in increasing strain on the right heart. It is a normal adaptive mechanism but if exaggerated can have serious consequences, resulting in life-threatening disorders and remodeling of the pulmonary circulation. Five mini-Review articles that comprise a Special Topic section in High Altitude Medicine & Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers provide an up-to-date overview of the clinical ...

Helping SAD sufferers sleep soundly

2013-06-28
PITTSBURGH—Lying awake in bed plagues everyone occasionally, but for those with seasonal affective disorder, sleeplessness is routine. University of Pittsburgh researchers report in the Journal of Affective Disorders that individuals with seasonal affective disorder (SAD)—a winter depression that leads to loss of motivation and interest in daily activities—have misconceptions about their sleep habits similar to those of insomniacs. These findings open the door for treating seasonal affective disorder similar to the way doctors treat insomnia. Kathryn Roecklein, primary ...

Biochemists identify protease substrates important for bacterial growth and development

2013-06-28
AMHERST, Mass. – Reporting this month in Molecular Microbiology, Peter Chien and colleagues at the University of Massachusetts Amherst describe using a combination of biochemistry and mass spectrometry to "trap" scores of new candidate substrates of the protease ClpXP to reveal how protein degradation is critical to cell cycle progression and bacterial development. The new understanding could lead to identifying new antibiotic targets. As Chien (pronounced Chen) explains, to carry out fundamental life processes such as growing and dividing, cells must orchestrate, in ...

Mapping out how to save species

2013-06-28
In stunning color, new biodiversity research from North Carolina State University maps out priority areas worldwide that hold the key to protecting vulnerable species and focusing conservation efforts. The research, published online in Proceedings of the National Academy of Sciences, pinpoints the highest global concentrations of mammals, amphibians and birds on a scale that's 100 times finer than previous assessments. The findings can be used to make the most of available conservation resources, said Dr. Clinton Jenkins, lead author and research scholar at NC State ...

A second amyloid may play a role in Alzheimer's disease, UC Davis researchers find

2013-06-28
A protein secreted with insulin travels through the bloodstream and accumulates in the brains of individuals with type 2 diabetes and dementia, in the same manner as the amyloid beta Αβ plaques that are associated with Alzheimer's disease, a study by researchers with the UC Davis Alzheimer's Disease Center has found. The study is the first to identify deposits of the protein, called amylin, in the brains of people with Alzheimer's disease, as well as combined deposits of amylin and plaques, suggesting that amylin is a second amyloid as well as a new biomarker ...

Low self-control promotes selfless behavior in close relationships

2013-06-28
When faced with the choice of sacrificing time and energy for a loved one or taking the self-centered route, people's first impulse is to think of others, according to new research published in Psychological Science, a journal of the Association for Psychological Science. "For decades psychologists have assumed that the first impulse is selfish and that it takes self-control to behave in a pro-social manner," says lead researcher Francesca Righetti of VU University Amsterdam in the Netherlands. "We did not believe that this was true in every context, and especially not ...

AIDSVu releases new maps that depict impact of HIV in America

2013-06-28
Today, on National HIV Testing Day, the Rollins School of Public Health at Emory University launched its annual update of AIDSVu, including new interactive online maps that show the latest HIV prevalence data for 20 U.S. cities by ZIP code or census tract. AIDSVu also includes new city snapshots displaying HIV prevalence alongside various social determinants of health – such as poverty, lack of health insurance and educational attainment. AIDSVu -- the most detailed publicly available view of HIV prevalence in the United States -- is a compilation of interactive online ...

Protein is involved with colon cancer cell's ability to invade other cells

2013-06-28
Understanding how the protein km23-1 enables in the spread of colon cancer may lead to new treatments for the disease, according to researchers at Penn State College of Medicine. Previous research shows that km23-1 is involved in the movement of cancer cells and in the control of specific proteins at the leading edge of moving cells. Kathleen Mulder, professor of biochemistry and molecular biology, who discovered the protein, now says km23-1 is used in the cancer cell's ability to move out of a tumor in the early stages of invasion. "km23-1 may be able to help in this ...

Aerial mosquito spraying study finds no immediate public health risks

2013-06-28
(SACRAMENTO, Calif.) — In what researchers say is the first public health study of the aerial mosquito spraying method to prevent West Nile virus, a UC Davis study analyzed emergency department records from Sacramento area hospitals during and immediately after aerial sprayings in the summer of 2005. Physicians and scientists from the university and from the California Department of Public Health found no increase in specific diagnoses that are considered most likely to be associated with pesticide exposure, including respiratory, gastrointestinal, skin, eye and neurological ...

Ritalin shows promise in treating addiction

2013-06-28
A single dose of a commonly-prescribed attention deficit hyperactivity disorder (ADHD) drug helps improve brain function in cocaine addiction, according to an imaging study conducted by researchers from the Icahn School of Medicine at Mount Sinai. Methylphenidate (brand name Ritalin®) modified connectivity in certain brain circuits that underlie self-control and craving among cocaine-addicted individuals. The research is published in the current issue of JAMA Psychiatry, a JAMA network publication. Previous research has shown that oral methylphenidate improved brain function ...

Could a diet high in fish and flax help prevent broken hips?

2013-06-28
COLUMBUS, Ohio – Higher levels of omega-3 fatty acids in the blood may reduce the risk for hip fractures in postmenopausal women, recent research suggests. Scientists analyzed red blood cell samples from women with and without a history of having a broken hip. The study showed that higher levels of omega-3 fatty acids from both plant and fish sources in those blood cells were associated with a lower likelihood of having fractured a hip. In addition to omega-3s, the researchers looked at omega-6 fatty acids, which are generally plentiful in a Western diet. The study ...

UT study: Chemical in antibacterial soaps may harm nursing babies

2013-06-28
KNOXVILLE—A mother's prolonged use of antibacterial soaps containing the chemical triclocarban may harm nursing babies, according to a recent study from the University of Tennessee, Knoxville. The study, which was conducted on rats, showed that exposure to the compound may reduce the survival rates of babies. Rebekah Kennedy, a UT graduate student pursuing a dual master's degree in public health and nutrition, and Jiangang Chen, an assistant professor in the UT Department of Public Health, presented the results this month at the Endocrine Society's 95th Annual Meeting ...

Radiation from airport scanners -- how much dose we get

2013-06-28
WASHINGTON D.C., June 26, 2013 -- A new report by an independent task force commissioned by the American Association of Physicists in Medicine (AAPM), has found that people absorb less radiation from airport X-ray backscatter scanner than they do while standing in line waiting for the scan itself. Measurements made on two scanners in active use at Los Angeles International Airport (LAX), as well as seven other scanners not in active use at the time of measurement, found that full-body scanners deliver a radiation dose equivalent to what a standard man receives every 1.8 ...

Gas-giant exoplanets cling close to their parent stars

2013-06-28
This news release is available in Spanish. Gemini Observatory's Planet-Finding Campaign finds that, around many types of stars, distant gas-giant planets are rare and prefer to cling close to their parent stars. The impact on theories of planetary formation could be significant. Finding extrasolar planets has become so commonplace that it seems astronomers merely have to look up and another world is discovered. However, results from Gemini Observatory's recently completed Planet-Finding Campaign – the deepest, most extensive direct imaging survey to date – show ...

Surgeons report melanoma recurs after 10 years in more than 6 percent of patients

2013-06-28
Chicago (June 27, 2013): Recurrence of melanoma skin cancer 10 or more years after initial treatment is more common than previously thought, occurring in more than one in 20 patients. However, according to a new study, these patients tend to live longer after their cancer returns than patients whose melanoma recurs in the first three years. The study results appear in the July issue of the Journal of the American College of Surgeons. "For patients with melanoma, survival beyond 10 years without a recurrence has been considered nearly synonymous with a cure," said principal ...

Telomere length influences cancer cell differentiation

2013-06-28
Researchers from the Japanese Foundation for Cancer Research in Tokyo have discovered that forced elongation of telomeres (extensions on the end of chromosomes) promotes the differentiation of cancer cells, probably reducing malignancy, which is strongly associated with a loss of cell differentiation. They report their findings in a manuscript published online ahead of print, in the journal Molecular and Cellular Biology. "Cancer cells may maintain short telomeres to maintain their undifferentiated state," says Hiroyuki Seimiya, a researcher on the study. Telomeres ...

Time is of the essence for reducing the long-term effects of iron deficiency

2013-06-28
Cincinnati, OH, June 28, 2013 -- Iron deficiency is a worldwide problem, especially in developing countries and among infants and pregnant women. In infancy, iron deficiency is associated with poorer cognitive, motor, and social-emotional outcomes. In a new study scheduled for publication in The Journal of Pediatrics, researchers report on a 25-year follow-up of infants studied in Costa Rica for iron deficiency. Betsy Lozoff, MD, and colleagues from the University of Michigan, Oakland University, and Instituto de Atención Pediátrica, Costa Rica, completed a 25-year ...
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