CHAPEL HILL, N.C. – A study from the University of North Carolina School of Medicine offers new insights into how the nervous system processes hot and cold temperatures. The research led by neuroscientist Mark J. Zylka, PhD, associate professor of cell biology and physiology, found an interaction between the neural circuits that detect hot and cold stimuli: cold perception is enhanced when nerve circuitry for heat is inactivated. "This discovery has implications for how we perceive hot and cold temperatures and for why people with certain forms of chronic pain, such as ...

An exploding star observed in 1604 by the German astronomer Johannes Kepler held a greater fraction of heavy elements than the sun, according to an analysis of X-ray observations from the Japan-led Suzaku satellite. The findings will help astronomers better understand the diversity of type Ia supernovae, an important class of stellar explosion used in probing the distant universe. "The composition of the star, its environment, and the mechanism of the explosion may vary considerably among type Ia supernovae," said Sangwook Park, an assistant professor of physics at the ...

HOUSTON – Guillermina "Gigi" Lozano, Ph.D., chair and professor in the Department of Genetics at The University of Texas MD Anderson Cancer Center, is the recipient of the 16th annual Women in Cancer Research Charlotte Friend Memorial Lectureship awarded by The American Association for Cancer Research (AACR), recognizing her contributions to the field of cancer research and the advancement of women in science. A pioneer in understanding the p53 tumor suppressor pathway, Lozano will deliver her award lecture, "Activities of Mutant p53 Proteins in Cancer," today as part ...

CAMBRIDGE, MA -- Nearly half of the world's population is at risk of infection by the dengue virus, yet there is no specific treatment for the disease. Now a therapy to protect people from the virus could finally be a step closer, thanks to a team at MIT. In a paper published today in the Proceedings of the National Academy of Sciences, the researchers, from MIT's Koch Institute of Integrative Cancer Research, present a novel approach to developing a dengue therapy using mutated antibodies. According to a study by the International Research Consortium on Dengue Risk ...

As any stepdad can tell you, it's one thing to win a mom's heart and another to win over her children. Although one-third of American children live in a stepfamily during part of their childhood, little is known about the development of the relationship between stepfathers and stepchildren. New research from Brigham Young University fills that gap with a study that identified three factors that significantly contribute to closeness in stepfamilies: The couple keeps arguments to a minimum Mothers help children feel comfortable sharing their frustrations The ...

(CHICAGO) – Older adults who are subject to elder abuse, neglect and exploitation face a greater risk of being hospitalized than other seniors, according to the results of a study published in the April 8 issue of JAMA Internal Medicine. "Elder abuse is independently associated with increased mortality risk, especially for cardiovascular related mortality. However, the relationship between elder abuse and health services utilization still remains unclear," said Dr. XinQi Dong, a researcher and geriatrician at Rush University Medical Center and the study's lead author. ...

The shape of an individual's spinal column may predict his or her risk for nursing home admission or need of home assistance in old age, according to a new article published online in the Journals of Gerontology Series A: Biological Sciences and Medical Sciences. A team of researchers based in Japan discovered that the trunk angle of inclination — the angle between the true vertical and a straight line from the first thoracic vertebra to the first sacral vertebra (view image) — is associated with becoming dependent on help for activities of daily living (ADL). These activities ...

COLUMBIA, Mo. — Studies show 97 percent of American adults get less than 30 minutes of exercise a day, which is the minimum recommended amount based on federal guidelines. New research from the University of Missouri suggests certain genetic traits may predispose people to being more or less motivated to exercise and remain active. Frank Booth, a professor in the MU College of Veterinary Medicine, along with his post-doctoral fellow Michael Roberts, were able to selectively breed rats that exhibited traits of either extreme activity or extreme laziness. They say these rats ...

Monday, April 8, 2013, Cleveland: Patients who have open heart surgery for heart disease caused by radiation cancer treatment are nearly twice as likely to die in the years following their surgery compared to similar patients who did not undergo radiation treatment, according to new research from Cleveland Clinic published today in the American Heart Association journal Circulation. The team of researchers, led by Milind Desai, M.D., a cardiologist in the Sydell and Arnold Miller Family Heart & Vascular Institute at Cleveland Clinic, examined 173 patients who underwent ...

(Santa Barbara, Calif.) –– There's an epic battle taking place that's not on the national radar: intercellular competition. While it's not an Olympic event, new research from UC Santa Barbara demonstrates that this microscopic rivalry can be just as fierce as humans going for the gold. Christopher Hayes, UCSB associate professor of molecular, cellular and developmental biology, along with postdoctoral fellow Sanna Koskiniemi, graduate student James Lamoureux, and others, examined the role certain proteins, called rearrangement hotspots (Rhs), play in intercellular competition ...

WASHINGTON—Teenagers who increased the days on which they got just 20 minutes of exercise were able to cut down on their smoking habit. And teenage smokers were more likely to quit altogether if they participated in a smoking cessation/fitness program—and they ramped up the days on which they got at least 30 minutes of physical activity, according to a study published online April 9. "This study adds to evidence suggesting that exercise can help teenagers who are trying to quit smoking," says lead author Kimberly Horn, EdD, the Associate Dean for Research at the George ...

Newly discovered mouse viruses could pave the way for future progress in hepatitis research, enabling scientists to study human disease and vaccines in the ultimate lab animal. In a study to be published in mBio®, the online open-access journal of the American Society for Microbiology, scientists describe their search for viruses related to the human hepatitis C virus (HCV) and human pegiviruses (HPgV) in frozen stocks of wild mice. The discovery of several new species of hepaciviruses and pegiviruses that are closely related to human viruses suggests they might be used ...

San Diego, CA, April 9, 2013 – A new study published in the May issue of the American Journal of Preventive Medicine finds that Google searches for information across all major mental illnesses and problems followed seasonal patterns, suggesting mental illness may be more strongly linked with seasonal patterns than previously thought. Monitoring population mental illness trends has been an historic challenge for scientists and clinicians alike. Typically, telephone surveys are used to try to glimpse inside the minds of respondents, but this approach is limited because ...

Two researchers at the National Institutes of Health discovered a new genetic link between the rapid growth of healthy fetuses and the uncontrolled cell division in cancer. The findings shed light on normal development and on the genetic underpinnings of common cancers. The work, conducted using mouse and human tissue, appears in today's issue of the Proceedings of the National Academy of Sciences. The authors, Julian C. Lui, Ph.D., and Jeffrey Baron, M.D., work at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). "We've long ...

Update on federal estate laws and impact on Connecticut estates Article provided by Riefberg, Smart, Donohue & NeJame, P.C. Visit us at http://www.rsdn.com The new federal estate tax rules for 2013 were passed during the fiscal cliff negotiations. This portion of the negotiations included an exclusion of up to $5.25 million in assets per person. This means each person can pass just over $5 million in assets to loved ones without paying taxes and each couple can exclude $10.5 million. This new amount is much larger than originally anticipated. Without the ...

Understanding protection from pregnancy discrimination in California Article provided by Larabee Law Firm Visit us at http://www.larabeelaw.com Too often expecting mothers face bias and discrimination in the workplace. Federal law affords pregnant workers protection from being treated differently than other employees in the workplace, and federal law also provides an amount of unpaid leave time for certain working mothers and fathers with newborns. However, pregnant workers in California are given even greater rights under state law. According to the National ...

Computer crimes carry harsh penalties Article provided by James S. Friedman, LLC Visit us at http://www.jfriedlawfirm.com The internet has changed the way we live. It has made it incredibly easy for individuals to stay connected with one another, even during the busiest of times. Many people work in occupations that depend on the internet to assist in the completion of daily tasks. Communities nationwide have realized how important it is to allow residence to have the systems in place that permit internet access. Most people use the internet for news and entertainment, ...

Warranties protect California consumers Article provided by The Law Offices of Michael S. Humphries Visit us at http://www.lemoncarsrus.com Californians might be aware that as buyers they have certain protections under the law. For example, they may have heard of California's "lemon law" that covers the purchase of a motor vehicle. Other kinds of purchases in California are also subject to consumer protections such as warranty laws. "Lemon law" provisions People who buy or lease a new vehicle in California have legal recourse if the vehicle ...

Chapter 7 versus Chapter 13 bankruptcy: Which is right for you? Article provided by James C. Warr & Associates, PLC Visit us at http://www.go2warr.com In these tough economic times, thousands of Americans are finding themselves overwhelmed by debt. While it is always a challenge to overcome financial difficulties, there are built in protections in the U.S. Bankruptcy Code that can help you wipe out your debt and get a fresh financial start. Yet, even though almost everyone has heard of bankruptcy, not all consumers are familiar with the types of bankruptcy ...

Researchers identify signs of brain damage in living NFL veterans Article provided by The Law Offices of Michael Goldstein Visit us at http://www.brainspinalcordinjuryattorneysandiego.com Researchers at the University of California, Los Angeles made an important breakthrough recently when they identified signs of potentially crippling brain damage in five former professional football players. The research involved performing brain scans on a group of former NFL players. In five of the players, scans revealed images of a telltale protein associated with a type ...

Forming a corporation in California Article provided by George C. Rudolph, A Professional Corporation Visit us at http://www.rudolphlawgroup.com Individuals who are interested in establishing a business in California should know that they have several options with regard to the type of business organization they form. When starting a new business, careful consideration should be given to federal and state formation and tax requirements, ownership and succession issues, whether the form of entity shields its owners from personal liability, and the extent to which ...

On April 5, the Lucentra Corporation's CEO, Jack Cola, and Chairman, Chuck Waters, visited the Gulf Stream factory. They leased the Gulf Stream 650, the fastest civilian jet available. It is a $57 million jet, but the Lucentra Corporation will be leasing for 6 years at $13 million a year. After the 6-year lease expires, the Gulf Stream finance corporation will allow Lucentra to purchase the jet at a discounted rate. The hours the jet has been in use will also determine how much the jet will cost at the end of those 6 years. However, Lucentra will likely purchase a new ...

Klaus Stohr, Vice President and Global Head of Influenza Franchises at Novartis, will give a keynote presentation titled "Global Trends in Pandemic Preparedness: Changes After the Last Pandemic?" at GTC's 2nd Influenza Research & Development Conference on July 8-10, 2013 in Boston, MA The last influenza pandemic highlighted the existing gaps in vaccine supply: limited global production capacity, owing to biological and technological realities 3-4 months are required before first vaccine doses are available, pandemic peaked before supply fully ramped up. ...

Independent game developer Hey Snails Inc. formally launched two new Facebook games at the recent Game Developers Conference - GDC Play Event in San Francisco. Game creators and company founders Redentor Quiambao and Harold Khan unveiled to a group of game enthusiasts, press and distributors their latest game release: Letter UP and Hey Snails Virtual World. Letter UP - play word game in real time Letter UP is a multiplayer word game that is played in 'real-time' - a key strength that many who have tried the game find really exciting and a lot more fun. The game was ...

Excite Holidays, an online B2B travel wholesaler, has appointed Peter Douglas as its new National Sales Manager. Mr Douglas' appointment as the National Sales Manager coincides with the company's national sales conference between management and the sales team to re-define the sales goals and strategy for the year. George Papaioannou, CEO of Excite Holidays said: "The appointment of Peter to coincide with our annual national sales conference was no coincidence. Peter is a master prospector with over 20 years travel industry experience and it's great to have someone ...