Engineers at Duke University have demonstrated a technique that uses microbubbles and ultrasound to help relatively large cancer drugs enter tumor cells and cause them to self-destruct. Dubbed “Sonoporation-assisted Precise Intracellular Nanodelivery”—or SonoPIN for short—the technology caused 50% of targeted cancer cells in a benchtop experiment to self-destruct, while leaving 99% of non-targeted cells healthy. The results show promise for precisely delivering a wide variety of large-molecule therapeutics to cells with few off-target effects. The research appears online March 13 in the journal Proceedings ...

In the middle of the old-growth forests of Congaree National Park in South Carolina, fireflies put on an other-worldly display every May. Thousands of male insects belonging to the species Photuris frontalis flash together at the same time and follow the exact same pattern—a synchronous light show you can see only in few places in the United States. Scientists and nature lovers have long been fascinated by how such simple insects can work together in perfect harmony.  In a new study, engineers from the University of Colorado Boulder have uncovered the mathematical rules fireflies follow to sync up their flashes. The team’s findings could one day lead to new designs for ...

The American Meteorological Society, joined by partner societies including the Ecological Society of America, the American Statistical Association, the Woodwell Climate Research Center, and the American Institute of Biological Sciences, has released a statement on “Public Availability of Scientific Information and Scientific Evidence on Climate Change” in response to the decision by the Federal Judiciary Center (FJC) to remove the climate science chapter from the Reference Manual on Scientific Evidence, Fourth Edition and a February letter from 21 state attorneys general urging the National Academies of Sciences, Engineering, and Medicine (NASEM) to omit similar guidance ...

Older Americans are willing to travel far for medical care — sometimes much farther than policymakers and experts assume, according to researchers at the USC Dornsife College of Letters, Arts and Sciences. Why it matters: As hospitals close in some areas, practices consolidate and telehealth expands, older adults may tolerate long trips for care — but not equally. The study suggests socioeconomic status affects willingness to travel. What’s new: A study published recently in JAMA Network Open finds that many Americans age 65 and older are willing to travel more than an hour for routine or specialized medical ...

A new University of Utah-led study has discovered the mechanism behind a decades-old evolutionary mystery—how “selfish chromosomes” cheat the rules of genetic inheritance. The researchers found that rogue chromosomes hijack the Overdrive (Ovd) gene to destroy rival sperm. The study is the first to identify that the Ovd gene acts as a quality control checkpoint during sperm development. Normally, Ovd detects and eliminates abnormal sperm cells. But selfish chromosomes exploit the system to kill competitors, boosting their chances of passing into the next generation.  The findings reveal the biology behind ...

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has found that excessive smartphone use is closely associated with disordered eating, including uncontrolled eating and emotional overeating, as well greater symptoms of food addiction in young people with no diagnosis of an eating disorder.  The research, published in the Journal of Medical Internet Research, established a significant and consistent association between Problematic Smartphone Use (PSU) - ...

A clean energy future hinges on minerals such as copper, cobalt, lithium and rare earth elements. But the race to secure them puts pressure on the places where they are mined, often affecting communities contributing the least to climate change. With some supply and processing concentrated in just a few countries, these critical raw materials (CRMs) have also become a geopolitical flashpoint. To secure CRM sources, the United States and European Union are moving supply chains to aligned regions—producing more at home, bringing industries ...

March 13, 2026—(BRONX, NY)—A research team led by Albert Einstein College of Medicine scientists has developed a new strategy to engineer immune cells that dramatically prolongs their effectiveness after being infused into patients to fight cancer and HIV, addressing a major limitation of current treatments. Their findings, published today in Science Advances, describe a manufacturing approach that, compared to the existing process, generates longer-lasting immune cells that provide more sustained control of human blood cancers and suppression of HIV-infection in mouse ...

Scientists in Sweden and the U.S. today reported the first-ever direct observation a type of short‑lived molecule that has shaped decades of thinking in atmospheric chemistry, combustion research and biomedical science. Publishing in Science Advances, researchers from KTH Royal Institute of Technology, in Stockholm, and Kinetic Chemistry Research in Mountain View, California, say their discovery of long-theorized, oxygen-rich tetroxides has implications in a number of sciences, including atmospheric chemistry, biochemistry ...

Contrary to what you and I might experience when we explore the world, our eyes do not provide us with a continuous and stable view of it. They jump several times each second in rapid movements called saccades. Because the eye projects the world onto the retina, we should see the world shift abruptly each time the eyes move—the visual scene should feel unstable, yet the brain uses sophisticated mechanisms that ensure it does not. A recent study, titled “High-fidelity but hypometric spatial localization of afterimages across ...

WASHINGTON and DALLAS (March 13, 2026) — The American College of Cardiology (ACC), the American Heart Association and nine other leading medical associations, today issued an updated guideline for the management of dyslipidemia—abnormal levels of one or more types of lipids or lipoproteins in the blood, including cholesterol and triglycerides. It is estimated 1 in 4 U.S. adults has high levels of low-density lipoprotein-cholesterol (LDL-C), which increase the risk of heart attack and stroke. The guideline consolidates evidence-based recommendations for managing dyslipidemias into one document, offering ...

UNIVERSITY PARK, Pa. — A long-running debate in vaccine design revolves around whether a vaccine should be optimized to prevent the virus from replicating inside an infected host or prevent the virus from transmitting to others. New research led by Penn State scientists suggests there may not have to be a tradeoff. The study in animal models, published today (March 13) in the journal Science Advances, demonstrates a way to stop the influenza virus from leaping from one host to the next while continuing to keep the virus from replicating inside the host. The findings reveal that the body’s defenses against two ...

Researchers at The University of Texas at Dallas have developed a new electrolyte system that significantly boosts the energy-harvesting performance of twistrons, which are carbon nanotube yarns that generate electricity when repeatedly stretched. The findings could aid in the manufacturing of intelligent textiles, such as fabrics used to make spacesuits, that would power wearable electronic devices or sensors by harvesting energy from human motion. In a study published in the Feb. 24 print edition of ACS Nano, the UT Dallas scientists and their collaborators reported that replacing conventional water with heavy water ...

The American Meteorological Society continuously publishes research on climate, weather, and water in its 12 journals. Many of these articles are available for early online access–they are peer-reviewed, but not yet in their final published form. Below are some recent examples of online and early-online research. JOURNAL ARTICLES 21st Century Hydrological Trends in the Mississippi River Basin Intensify the East to West Moisture Gradient Journal of Climate Models suggest precipitation and evaporation will both increase in the Mississippi basin. A study combining 19 climate models suggests that under a medium-high carbon emissions scenario (SSP3-7.0), ...

A genetic mutation that helps animals like yaks and Tibetan antelopes survive at high altitudes may hold the key to repairing nerve damage in conditions such as cerebral paralysis and multiple sclerosis (MS). The finding, publishing March 13 in the Cell Press journal Neuron, reveals a naturally existing pathway that promotes regeneration after nerve damage and could open new doors for treating diseases like MS by leveraging molecules that are already present in the human body.  “Evolution is a great gift from nature, providing a rich diversity of genes that help ...

Efficient methanol synthesis is considered a promising approach for carbon resource recycling. Hydrogenation of carbon dioxide (CO2) to methanol is thermodynamically favored at low temperatures, but the sluggish activation kinetics of CO2 under such conditions lead to low catalytic activity. Higher temperatures can enhance reaction rates but also promote the reverse water-gas shift side reaction, which reduces methanol selectivity. This "seesaw" effect between activity and selectivity has long limited improvements ...

About The Study: In this mixed-methods cohort study, functional recovery in the first 6 months after noncardiac major elective surgery was associated with daily living impairment for older adults and their caregivers. Targeted interventions including preoperative education, caregiver-inclusive discharge planning (e.g., wound-care teaching, how to recognize complications and what to do for support, and more rehabilitation), and early follow-up after discharge may optimize recovery experiences.  Corresponding Author: To contact the corresponding author, Martine Puts, RN, PhD, email martine.puts@utoronto.ca. To ...

About The Study: This cohort study found that despite their reported advantages and consensus endorsement, heterogeneous adoption of donor care units (DCUs) has left a substantial proportion of deceased donors after brain death more than a 180-minute drive from a DCU. Given inefficiencies introduced by donation service area boundaries, opening additional DCUs in acute care hospitals and donor transport across these existing boundaries may be 2 potential approaches to improve system efficiency and donation outcomes.  Corresponding ...

MLIP calculations successfully identify suitable dopants for a novel photocatalytic material, report researchers from Institute of Science Tokyo. As demonstrated in their latest study, a materials informatics approach could predict which ions can be stably introduced into orthorhombic Sn3O4, a promising and recently discovered photocatalytic tin oxide. Their experiments revealed that aluminum-doped samples achieved 16 times greater hydrogen production than the undoped material, paving the way for next-generation clean energy applications. Building a sustainable hydrogen economy requires clean and efficient ways to produce hydrogen at scale. One particularly ...

“Sulfur amino acid restriction (SAAR), a diet low in methionine and lacking cysteine, reduces obesity but also lowers bone mineral density (BMD) and increases marrow adipose tissue.” BUFFALO, NY — March 13, 2026 — A new research paper was published in Volume 18 of Aging-US on March 2, 2026, titled “D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice.” Led by Naidu B. Ommi from the Orentreich Foundation for the Advancement ...

Digital subtraction angiography remains the gold standard for diagnosing cerebrovascular diseases, including intracranial aneurysms, arteriovenous malformations, and arterial stenosis. However, the procedure requires operators to work under fluoroscopic guidance, resulting in prolonged exposure to ionizing radiation. To address this issue, vascular interventional robotic systems have been developed to allow operators to perform procedures remotely from the radiation zone. In a study published in Volume ...

In reptiles, a simple temperature change can determine whether an egg develops into a male or female. This process is formally known as temperature-dependent sex determination (TSD), in which the sex of an embryo is determined by the temperature it experiences during a specific window of development known as the temperature-sensitive period. For example, in American alligators, incubation at around 30 °C typically produces females, while temperatures near 33 °C produce males, although extremely ...

After years of research, international experts have confirmed the discovery of a new chemical reaction, launching new opportunities for rapid advances in a range of fields – from recycled plastics to pharmaceuticals. In a major new article in top-ranking journal Nature Chemistry, the interdisciplinary team explore how sulfur-sulfur bonds can be formed and broken rapidly and cleanly at room temperature, opening new avenues for drug development, biotech and protein science, and chemical and material science. “It is rare to discover an entirely new reaction, and even more ...

Every animal carries a microscopic community of bacteria, fungi and other microbes that play a critical role in health. These gut microbes help regulate the immune system, support digestion, and even influence how animals respond to stress. In birds, stress triggers the hormone corticosterone, which helps individuals cope with challenges. But when stress is prolonged or repeated, it can disrupt the balance of microbes in the gut, potentially affecting health in ways that aren’t immediately visible. While scientists have studied these stress–microbiome links extensively in mammals and domestic birds, little is known ...

Researchers at Mass General Brigham have developed a series of artificial intelligence (AI) tools that uses machine learning to identify individuals who may be at risk for intimate partner violence (IPV) using information from their electronic medical records (EMRs). In a study published in npj Women’s Health, the researchers report the tools could detect IPV up to four years before the individual sought care at a domestic violence treatment center. The findings highlight its potential for proactive screening and supporting healthcare providers in initiating earlier conversations about IPV with patients. "Our research offers proof of concept that AI can support clinicians ...