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Nationwide study looks at when and where EV owners use public charging stations

2024-12-10
AUSTIN, TX, Dec 10, 2024 – Electric Vehicles (EVs) represent a promising mode of transportation that can help the United States reduce its carbon emissions. But barriers such as the high cost of installing and using EV Charging Stations (EVCS), their limitations in supplying emerging demand, and their uneven distribution throughout the country limit access for many Americans.   Researchers at the University of Maryland are using supercomputers and machine learning methods to analyze a full year of real-time data collected from individual EV charging ports at more than 50,000 publicly available stations throughout the country. The primary focus of the study is ...

A new discovery about the source of the vast energy in cosmic rays

2024-12-10
Ultra-high energy cosmic rays, which emerge in extreme astrophysical environments—like the roiling environments near black holes and neutron stars—have far more energy than the energetic particles that emerge from our sun. In fact, the particles that make up these streams of energy have around 10 million times the energy of particles accelerated in the most extreme particle environment on earth, the human-made Large Hadron Collider. Where does all that energy come from? For many years, scientists believed it came from ...

Cancer ‘fingerprint’ can improve early detection

Cancer ‘fingerprint’ can improve early detection
2024-12-10
Different types of cancer have unique molecular ‘fingerprints’ which are detectable in early stages of the disease and can be picked up with near-perfect accuracy by small, portable scanners in just a few hours, according to a study published today in the journal Molecular Cell.   The discovery by researchers at the Centre for Genomic Regulation (CRG) in Barcelona sets the foundation for creating new, non-invasive diagnostic tests that detect different types of cancer faster and earlier than currently possible.   The study centres around the ribosome, the protein factories of a cell. For decades, ribosomes were thought ...

Rethinking the brain pacemaker: How better materials can improve signals

Rethinking the brain pacemaker: How better materials can improve signals
2024-12-10
WASHINGTON, Dec. 10, 2024 – Two years ago, a medical professional approached scientists at the University of Tabriz in Iran with an interesting problem: Patients were having headaches after pacemaker implants. Working together to investigate, they began to wonder if the underlying issue is the materials used in the pacemakers. “Managing external noise that affects patients is crucial,” author Baraa Chasib Mezher said. “For example, a person with a brain pacemaker may experience interference from external electrical fields from phones ...

Allostatic load, educational attainment, and risk of cancer mortality among us men

2024-12-10
About The Study: This study highlights the detrimental association of not attaining a high school degree, combined with high allostatic load as a marker of chronic stress, with cancer mortality. Efforts to promote educational attainment and address the underlying social determinants of health are imperative in reducing cancer disparities in this population.  Corresponding Author: To contact the corresponding author, Justin X. Moore, PhD, MPH, email jx.moore@uky.edu. To access the embargoed study: Visit our For The Media website at this link ...

Flaw in computer memory leads to global security fixes

2024-12-10
Cyber security experts studying memory modules in computers have uncovered a key security weakness that has led to worldwide security fixes in AMD computer processors.  The weakness occurs because of ‘BadRAM’ - rogue memory modules that deliberately provide false information to the computer’s processor during startup.  Processors are present in every computer and are necessary to perform every calculation. The computer’s memory (DRAM) is essential for storing code and data. When a computer ...

Race, ethnicity, and sleep in us children

2024-12-10
About The Study: In this cross-sectional study of children’s sleep disparities, racially and ethnically minoritized children exhibited disparities in mean levels and variability of sleep compared with their white peers. These findings suggest that policies and practices should target multiple sleep dimensions among diverse racial and ethnic groups to promote equitable pediatric sleep health.  Corresponding Author: To contact the corresponding author, Yijie Wang, PhD, email yjwang@msu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.49861) Editor’s ...

Geriatric surgery verification program can improve outcomes for older cancer patients in community hospitals

2024-12-10
Key takeaways  The American College of Surgeons Geriatric Surgery Verification program significantly decreases hospital stays among older cancer patients, according to researchers who implemented the program at their institution.  After implementing the program, patients undergoing major abdominal oncologic procedures also maintained higher levels of independence and were more likely to be discharged home.  Researchers found the program addresses the unique needs of older cancer patients by focusing on multiple aspects of care.  CHICAGO — ...

Pew funds 8 teams to conduct collaborative biomedical research

2024-12-10
PHILADELPHIA—The Pew Charitable Trusts announced today the eight pairs of researchers who will make up its 2024 class of Innovation Fund investigators. These 16 acclaimed scientists—all alumni of Pew’s biomedical programs in the United States and Latin America—will collaborate on interdisciplinary research projects that explore foundational questions about human biology and disease. By combining their expertise in topic areas ranging from cell biology and immunology to neuroscience and genetics, these partnerships will help to advance scientific discovery and improve human ...

Finding innovative ways to address kidney cancer leads to DoD grant

2024-12-10
Weill Cornell Medicine has received a $1.4 million, four-year grant from the U.S. Department of Defense to investigate a new therapeutic approach for the most common form of kidney cancer. The grant is one of 10 Idea Awards the department funded this year to support innovative, high-risk, high-reward science that could lead to a paradigm shift in cancer care. The funding will enable principal investigators Dr. Lorraine Gudas and Dr. David Nanus to explore a cellular reprogramming strategy that may improve how patients ...

Americans are uninformed about and undervaccinated for HPV

Americans are uninformed about and undervaccinated for HPV
2024-12-10
LOS ANGELES — The human papillomavirus (HPV), a common sexually transmitted infection, accounts for 70% of all throat cancers, according to the National Cancer Institute. While commonly associated with cervical cancer, throat cancer is now the most common type of HPV-related cancer.  However, the majority of American adults are unaware that HPV can cause throat cancer and are not taking advantage of the one proven method for prevention — the HPV vaccine.   These are the conclusions of two recent studies from the USC Head and Neck Center, part of Keck Medicine of USC and the USC Caruso Department of Otolaryngology – ...

KTU scientists developed a nanolaser: silver nanocubes enable light generation

KTU scientists developed a nanolaser: silver nanocubes enable light generation
2024-12-10
Kaunas University of Technology (KTU), Lithuania researchers and scientists from Japan have developed a unique nanolaser. Although the dimensions of this laser are so small that its structure can only be seen through a powerful microscope, its potential is vast. With applications in early medical diagnostics, data communication, and security technologies, this invention could also become a key tool for the study of light and matter interactions. Depending on the application, lasers differ in the way light is amplified and produced, which determines the colour of the radiation and the quality of the laser ...

Insilico Medicine nominates orally available pre-clinical candidate targeting NLRP3 to treat inflammation and central nervous system diseases

Insilico Medicine nominates orally available pre-clinical candidate targeting NLRP3 to treat inflammation and central nervous system diseases
2024-12-10
As the first line against microbial infections or endogenous cellular damage in our body, the innate immune system utilizes NLRs (NOD-like receptors) to sense the molecules triggering microbial infection and damage, thus ensuring the proper immune response function. In the NLRs family, NLRP3 is the most characterized member, and its overactivation can lead to excessive production of pro-inflammatory cytokines and chemokines, driving pathological processes in various inflammatory diseases. CAMBRIDGE, Mass., Dec 10, 2024 --- Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven drug discovery ...

PLOS receives $3.3 million grant to support Open Access publishing & business model transformation

2024-12-10
SAN FRANCISCO — FOR IMMEDIATE RELEASE PLOS has been awarded a $3.3million grant from the Bill & Melinda Gates Foundation, underscoring its commitment to pioneer a shift away from traditional publishing models. The 3-year funding package from the Gates Foundation will support PLOS’ transition towards APC-free publishing by enabling authors, funded by the foundation, to publish with PLOS without facing APC barriers, and to contribute to open access publishing options for authors who do not have access to funding. This 3-year grant offers support while PLOS is actively working on new publishing models grounded in open science starting with ...

HBx facilitates drug resistance in hepatocellular carcinoma via CD133-regulated self-renewal of liver cancer stem cells

HBx facilitates drug resistance in hepatocellular carcinoma via CD133-regulated self-renewal of liver cancer stem cells
2024-12-10
Background and Aims Hepatitis B virus (HBV) infection contributes to hepatocellular carcinoma (HCC) tumorigenesis, drug resistance, and recurrence, although the underlying molecular mechanisms remain unclear. Recent studies suggest that HBV infection may be associated with liver cancer stem cells (LCSCs), but the exact mechanisms are yet to be resolved. In this study, we aimed to analyze the role of HBV infection in regulating the stemness of HCCs, which is closely linked to drug resistance. Methods Sphere formation assay and real-time Polymerase Chain Reaction quantification were used to ...

ASN congratulates members for their role in the development of the Scientific Report of the 2025 Dietary Guidelines Advisory Committee

2024-12-10
Rockville, MD – December 10, 2024 –The American Society for Nutrition (ASN) applauds the release of the Scientific Report of the 2025 Dietary Guidelines Advisory Committee (DGAC). The Society is pleased to note that 19 of the 20 Committee members are ASN members, including the Chair, ASN President Sarah Booth, and Vice Chair, Angela Odoms-Young, a member of the ASN Board of Directors. The DGAC is an independent panel of nutrition science experts tasked to review the state of the evidence on nutrition-related topics and scientific questions identified by the U.S. Department of Agriculture (USDA) ...

Late-stage breast cancer diagnosis on the rise in US

Late-stage breast cancer diagnosis on the rise in US
2024-12-10
OAK BROOK, Ill. – The number of women with late-stage, invasive breast cancer at the time of diagnosis increased significantly among U.S. women across all ages and ethnicities between 2004 and 2021, according to a study published today in Radiology, a journal of the Radiological Society of North America (RSNA). In the study, researchers analyzed the latest available Surveillance, Epidemiology, and End Results (SEER) data on annual stage-specific breast cancer incidence rates between 2004 and 2021. SEER data is collected from 22 population-based ...

Brain volume changes seen in opioid users

Brain volume changes seen in opioid users
2024-12-10
OAK BROOK, Ill. – Researchers at the Yale School of Medicine found structural and functional alterations in specific brain regions of individuals with opioid use disorder. The study’s results were published today in Radiology, a journal of the Radiological Society of North America (RSNA). Opioids are a class of drugs that include synthetic opioids such as fentanyl, prescription pain relievers like oxycodone, and illegal narcotics, including heroin. Opioids have a high potential for misuse, and opioid use is a major contributor to drug overdoses in the ...

Ultra-processed foods may drive colorectal cancer risk, USF-TGH study finds

Ultra-processed foods may drive colorectal cancer risk, USF-TGH study finds
2024-12-10
Media Contact: John Dudley (814) 490-3290 (cell) jjdudley@usf.edu EMBARGOED FOR PUBLICATION UNTIL TUESDAY, DEC. 10, AT 10 A.M. ET TAMPA, Fla. (Embargoed until Dec. 10, 2024) – Colorectal cancer, the second leading cause of cancer-related deaths in the United States, may be fueled by the food on our plates. Researchers at the University of South Florida and Tampa General Hospital Cancer Institute have uncovered a potential link between the Western diet – dominated by ultra-processed foods and unhealthy oils – and the chronic inflammation that drives ...

Two Case Western Reserve University faculty members honored as Fellows of the National Academy of Inventors

Two Case Western Reserve University faculty members honored as Fellows of the National Academy of Inventors
2024-12-10
Polymer scientist Gary E. Wnek and stem-cell biologist Arnold Caplan have been named Fellows of the National Academy of Inventors (NAI), the highest professional distinction awarded solely to inventors. The two Case Western Reserve University faculty members will be inducted June 26 at the NAI’s 14th annual conference in Atlanta. Caplan, who was nominated in 2023, died in January. The NAI said his family will be invited to accept the medal in his honor. The NAI Fellows Program was established “to highlight academic ...

How this cancer drug could make radiation a slam dunk therapy

2024-12-10
UCSF scientists combine a precision drug therapy with an antibody and radiation to eliminate tumors without causing side effects.  Radiation is one of the most effective ways to kill a tumor. But these therapies are indiscriminate, and they can damage healthy tissues.  Now, UC San Francisco scientists have developed a way to deliver radiation just to cancerous cells. The therapy combines a drug to mark the cancer cells for destruction and a radioactive antibody to kill them.   It wiped out bladder and lung tumors in mice ...

National TRAP Program funds large-scale cleanup of discarded fishing gear

National TRAP Program funds large-scale cleanup of discarded fishing gear
2024-12-10
A massive cleanup of derelict fishing gear in U.S. coastal waters is set to begin now that William & Mary’s Batten School & VIMS has awarded $1.4 million to fund 11 projects under the National Fishing Trap Removal, Assessment, and Prevention (TRAP) Program. From diving in waters up to 130 feet deep to retrieve lobster and crab traps in protected ecosystems to the removal of debris in tribal fishing grounds, this initial round of projects facilitates removal efforts in California, Connecticut, Delaware, Florida, Louisiana, Maine, Maryland, ...

Using ‘biological age’ to predict early colorectal cancer risk

Using ‘biological age’ to predict early colorectal cancer risk
2024-12-10
MIAMI, FLORIDA (EMBARGOED UNTIL Dec. 10, 2024, AT 10AM EST) – New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine suggests that one’s biological age, which can be higher than his or her chronological age – a concept called accelerated aging – may predict who’s at risk for developing colon polyps, a known risk factor for colorectal cancer. The findings, published in Cancer Prevention Research, a journal of the American Association for Cancer Research, link accelerated aging to increased early colorectal cancer ...

National Academy of Inventors announces Class of 2024 Fellows

2024-12-10
The National Academy of Inventors (NAI) announced today the election of 170 exceptional inventors into the 2024 Class of Fellows. NAI Fellowship is the highest professional distinction awarded solely to inventors. The full list of 2024 Fellows can be found here. The 2024 cohort of Fellows exemplifies the Academy’s belief that groundbreaking innovation knows no bounds and inventors can be found everywhere. This is evident in the fact that the honorees represent 39 U.S. states, 12 countries, and 43% identify as underrepresented ...

SwRI showcases capabilities, evaluates novel fire-safety method with customized test

SwRI showcases capabilities, evaluates novel fire-safety method with customized test
2024-12-10
SAN ANTONIO — December 10, 2024 — Southwest Research Institute successfully customized and conducted a full-scale evaluation of a novel fire mitigation method designed to safely store damaged electric vehicles and batteries. SwRI engineers demonstrate customized research and development support for government and industry clients with novel projects and challenges related to emerging technologies where no standardized testing exists. “SwRI established the nation’s first fire-focused research program 75 years ago, so our extensive ...
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