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Space 2013-09-20

Southwestern Gulf system 95L targeted by NASA's Global Hawk

NASA's Aqua satellite passed over a developing low pressure area in the southwestern Gulf of Mexico and captured infrared data on what is now the latest destination for NASA's Hurricane and Severe Storms Sentinel mission. On Sept. 19, NASA's HS3 mission sent an unmanned Global Hawk aircraft to investigate and gather data from low pressure System 95L, located in the Bay of Campeche. On Sept. 19 at 07:35 UTC/3:35 a.m. EDT, NASA's Aqua satellite passed over System 95L and the Atmospheric Infrared Sounder instrument or AIRS instrument that flies aboard it captured infrared ...
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Medicine 2013-09-20

Songbirds may have 'borrowed' DNA to fuel migration

A common songbird may have acquired genes from fellow migrating birds in order to travel greater distances, according to a University of British Columbia study published this week in the journal Evolution. While most birds either migrate or remain resident in one region, the Audubon's warbler, with habitat ranging from the Pacific Northwest to Mexico, exhibits different behaviours in different locations. The northern populations breed and migrate south for the winter, while southern populations have a tendency to stay put all year long. Evolutionary biologists have ...
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Science 2013-09-20

Mine metals at Maine Superfund site causing widespread contamination

Toxic metals from the only open pit mine in an estuary system in the United States are widespread in nearby sediment, water and fish and may be affecting marine and coastal animals that feed on them beyond the mine site, a new Dartmouth study finds. Mining contamination's effects on human health and aquatic and terrestrial wildlife is well documented in the United States, but the Dartmouth study is one of the first to look at the impacts of an open pit mine on an estuarine environment and the coastal marine food web. The results, which appear in the journal Archives ...
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Medicine 2013-09-20

Higher calorie diets increase weight gain, shorten hospital stays for teens with anorexia

Higher calorie diets produce twice the rate of weight gain compared to the lower calorie diets that currently are recommended for adolescents hospitalized with anorexia nervosa, according to a study by researchers at UCSF Benioff Children’s Hospital. The findings will be published in the November issue of the Journal of Adolescent Health along with an accompanying editorial and two supporting studies, challenging the current conservative approach to feeding adolescents with anorexia nervosa during hospitalization for malnutrition. “These findings are crucial ...
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Medicine 2013-09-20

Tiger, lion and leopard genomes revealed assisting big cats' conservation

September 20, 2013, Shenzhen, China – An international team led by South Korea's Personal Genomics Institute and BGI unraveled the first whole genome of a 9-year-old male Amur tiger (Panthera tigris altaica), and compared it with the genomes of other big cats including the white Bengal tiger, lions, and snow leopards. The genomic data from this study provides an invaluable resource for the future studies of big cats and their whole family's conservation. The latest study was published online in Nature Communications. Despite big cats' reputation for ferocity, these majestic ...
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Medicine 2013-09-20

Imaging technique detects pediatric liver disease without need for needle biopsy

A new, non-invasive imaging technique, magnetic resonance elastography (MRE), can now help physicians accurately detect fibrosis (scarring) in children with chronic liver disease – a growing problem due in part to increasing obesity rates. A new study shows that MRE detects such chronic diseases as non-alcoholic fatty liver disease (NAFLD), which is increasingly common in children and teens, affecting an estimated 13 percent of adolescents. NAFLD can lead to progressive liver disease and liver failure. Obesity is a major risk factor. "Because many pediatrics patients ...
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Science 2013-09-20

Virginia Tech scientists show why traumatized trees don't 'bleed' to death

Why don't trees "bleed" to death when they are injured? Researchers from Virginia Tech, the Georg-August University of Gottingen, Germany, and the Jackson Laboratory of Bar Harbor, Maine, have discovered how "check valves" in wood cells control sap flow and protect trees when they are injured. The study, featured on the cover of the September issue of the American Journal of Botany, used a special microscope to reveal how nanostructures help contain damage within microscopic cavities called bordered pits in wood-fiber cells. The pits allow sap to circulate through adjacent ...
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Medicine 2013-09-20

Climate change: Polar bears change to diet with higher contaminant loads

Researchers expect the climate to become warmer in the future and predict that climate change will have a significant impact on the Arctic. How will a warming Arctic affect the polar bears? The East Greenlandic population of polar bears resides in an area, where the Arctic sea ice is expected to disappear very late. However, the decline in the ice sheet here occurs at a rate of almost 1% per year, one of the highest rates measured in the entire Arctic region. How does this affect the prey of the polar bears - and, in turn, the polar bears' intake of contaminants? An international ...
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Science 2013-09-20

Transmitting future asthma by smoking today

Bethesda, Md. (Sept. 20, 2013)—Asthma is a serious public health problem. An estimated 300 million people worldwide suffer from this sometimes deadly lung disease, a number expected to increase to 400 million by 2025. One well-established risk factor for asthma is having a mother who smoked during her pregnancy. However, researchers recently discovered that smoking can have a lasting legacy. When animal mothers are exposed to nicotine during pregnancy—a proxy for smoking—their grandchildren were also at an increased risk of asthma, even though they were never exposed to ...
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Medicine 2013-09-20

Final piece found in puzzle of brain circuitry controlling fertility

In a landmark discovery, the final piece in the puzzle of understanding how the brain circuitry vital to normal fertility in humans and other mammals operates has been put together by researchers at New Zealand's University of Otago. Their new findings, which appear in the leading international journal Nature Communications, will be critical to enabling the design of novel therapies for infertile couples as well as new forms of contraception. The research team, led by Otago neuroscientist Professor Allan Herbison, have discovered the key cellular location of signalling ...
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Medicine 2013-09-20

Digoxin use associated with higher risk of death for patients diagnosed with heart failure

OAKLAND, Calif., Sept. 20, 2013 — Digoxin, a drug commonly used to treat heart conditions, was associated with a 72 percent higher rate of death among adults with newly diagnosed systolic heart failure, according to a Kaiser Permanente study that appears in the current online issue of Circulation: Cardiovascular Quality and Outcomes. Digoxin is a drug derived from digitalis, a plant that has been used for more than 200 years to treat heart failure. "These findings suggest that the use of digoxin should be reevaluated for the treatment of systolic heart failure in contemporary ...
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Medicine 2013-09-20

Scripps Research Institute study explores barriers to HIV vaccine response

LA JOLLA, CA -- Researchers at The Scripps Research Institute (TSRI) discovered that an antibody that binds and neutralizes HIV likely also targets the body's own "self" proteins. This finding could complicate the development of HIV vaccines designed to elicit this protective antibody, called 4E10, and others like it, as doing so might be dangerous or inefficient. "We developed two new mouse models that allow us to visualize the fate of the rare B cells that can see HIV and we thought could be stimulated by vaccines to produce neutralizing antibodies -- the type of antibodies ...
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Science 2013-09-20

The higher the better?

High-intensity exercise is shown to be protective against coronary heart disease (CHD) and is well known as a popular and time-saving approach to getting fit. But what about people who already have heart disease? Previously, these patients were told to exercise, but only at a moderate intensity to protect their hearts. More recently, however, researchers have found that high-intensity exercise is very beneficial for these patients. But how intense should these sessions actually be? A new study from the K. G. Jebsen -- Center of Exercise in Medicine at the Norwegian University ...
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Medicine 2013-09-20

Building the best brain: U-M researchers show how brain cell connections get cemented early in life

ANN ARBOR, Mich. -- When we're born, our brains aren't very organized. Every brain cell talks to lots of other nearby cells, sending and receiving signals across connections called synapses. But as we grow and learn, things get a bit more stable. The brain pathways that will serve us our whole lives start to organize, and less-active, inefficient synapses shut down. But why and how does this happen? And what happens when it doesn't go normally? New research from the University of Michigan Medical School may help explain. In a new paper in Nature Neuroscience, a ...
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Science 2013-09-20

Gap closed in the genetic map of kingdom fungi

Today, the genomes of more than 250 fungi have been sequenced. Among the basal filamentous ascomycetes – a group of ascomycetes that includes e.g. truffles and morels – only one representative has been analysed so far: the truffle Tuber melanosporum. "With 125 million base pairs, the truffle genome is unusually big, yet it is coding for relatively few genes, namely some 7,500," says Minou Nowrousian from the Department of General and Molecular Botany. "Until now, it was not clear whether this is typical of basal filamentous ascomycetes or whether it is caused by the truffle's ...
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Medicine 2013-09-20

Lifestyle influences metabolism via DNA methylation

In the course of life, aging processes, environmental influences and lifestyle factors such as smoking or diet induce biochemical alterations to the DNA. Frequently, these lead to DNA methylation, a process in which methyl groups are added to particular DNA segments, without changing the DNA sequence. Such processes can influence gene function and are known as epigenetics. Scientists of the Institute of Genetic Epidemiology (IGE) and the Research Unit Molecular Epidemiology (AME) at Helmholtz Zentrum München are seeking to determine what association exists between these ...
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Science 2013-09-20

New rat genus discovered in the birthplace of the theory of evolution

A prominent tuft of spiny hair on the back, a white tail tip and three pairs of teats represent the unique set of characteristics describing a new genus of rat which has been discovered in the Moluccan province of Indonesia. This region had a profound influence on the British Naturalist Alfred Russell Wallace who independently developed the theory of evolution alongside Charles Darwin. The international team of zoologists was led by the Museum Zoologicum Bogoriense in Indonesia and the Center for Macroecology, Evolution and Climate at the University of Copenhagen. One ...
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Science 2013-09-20

Getting rid of unwanted visitors

The digestive systems of all animals contain a large number of different bacteria. Humans are no exception and our intestines provide warmth, shelter and food to a vast range of unicellular organisms, many of which are either beneficial to their hosts or at least cause no ill effects other than consuming some of the food we ingest. However, several species have been associated with disease. Among them is Helicobacter pylori, which may play a part in causing chronic gastritis and gastric ulcers. An ancient colonizer recently discovered Helicobacter pylori was only discovered ...
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Science 2013-09-20

Crucial new insight into the secrets of Nobel Prize-winning pump

The story of the sodium-potassium pump has strong ties to Denmark. In 1997, the Danish scientist Jens Chr. Skou received the Nobel Prize in Chemistry for his discovery, and over the years, research on the pump has remained a strong focus area at Aarhus University. In 2007, the joint efforts of various research teams at Aarhus University led to the description of the structure of the potassium-bound state of the pump - now, Danish researchers have also described the other state of the pump; the sodium-bound state. The results were recently published in the journal Science. The ...
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Medicine 2013-09-20

New research on inherited herpesvirus may have implications for transplantation

Up to half a million people in Britain today may not know it, but in their genetic material they carry a particular form of herpesvirus 6 inherited from a parent. The study from the world-renowned Department of Genetics at the University of Leicester, is funded principally by the Medical Research Council (MRC), and published in the journal Nucleic Acids Research. The research led by Dr Nicola Royle, Senior Lecturer in Genetics, has identified a mechanism by which the inherited herpesvirus 6 can escape from the chromosome and may be able to reactivate under certain ...
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Medicine 2013-09-20

Elvitegravir fixed combination in HIV: Lesser benefit for treatment-naive patients

The drug combination of elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil (elvitegravir fixed combination, trade name: Stribild) has been approved in Germany since May 2013 for the treatment of adults infected with human immunodeficiency virus type 1 (HIV-1). In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether an added benefit is proven for this combination over the current standard therapy. This is not the case: ...
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Medicine 2013-09-20

Blood pressure cuff may save lives in patients with acute heart attack

In patients with an acute heart attack, remote ischemic conditioning – intermittent inflation of a blood pressure cuff to cut off blood flow to the arm during transportation to hospital for acute balloon dilatation – reduces subsequent cardiac symptoms and mortality after acute heart attack. The results are presented by researchers from Aarhus University Hospital and Aarhus University in European Heart Journal on-line 12 September 2013. Activating the body's defense mechanism Lack of oxygen for short periods of time in a distant organ by intermittently stopping blood ...
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Science 2013-09-20

Promising new alloy for resistive switching memory

WASHINGTON, D.C. Sept. 20, 2013 -- Memory based on electrically-induced "resistive switching" effects have generated a great deal of interest among engineers searching for faster and smaller devices because resistive switching would allow for a higher memory density. Researchers have tested a number of oxide materials for their promise in resistive switching memories, and now a team of researchers in Singapore have demonstrated how conductive nano-filaments in amorphous titanium dioxide (TiO2) thin films could be utilized for resistive switching device applications. Yuanmin ...
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Environment 2013-09-20

Densest array of carbon nanotubes grown to date

WASHINGTON, D.C. Sept. 20, 2013 -- Carbon nanotubes' outstanding mechanical, electrical and thermal properties make them an alluring material to electronics manufacturers. However, until recently scientists believed that growing the high density of tiny graphene cylinders needed for many microelectronics applications would be difficult. Now a team from Cambridge University in England has devised a simple technique to increase the density of nanotube forests grown on conductive supports about five times over previous methods. The high density nanotubes might one day replace ...
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Medicine 2013-09-20

Microfluidic platform gives a clear look at a crucial step in cancer metastasis

CAMBRIDGE, Mass-- Cancer cells metastasize in several stages -- first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually forming a secondary tumor. While the initial process by which cancer cells enter the bloodstream -- called intravasation -- is well characterized, how cells escape blood vessels to permeate other tissues and organs is less clear. This process, called extravasation, is a crucial step in cancer metastasis. Now researchers at MIT ...
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