In a randomized trial that included about 2,000 patients with or at high risk of cardiovascular disease (CVD), use of a fixed-dose combination medication for blood pressure, cholesterol, and platelet control compared to usual care resulted in significantly improved medication adherence after 15 months and small improvements in systolic blood pressure and low-density lipoprotein cholesterol, according to a study in the September 4 issue of JAMA. "The long-term use of cardiovascular disease preventive therapy is low among people with established disease. This shortfall ...

In a study that included more than 140,000 participants from17 countries of varying income levels, researchers found a large gap between both detection and control of hypertension across all countries studied, with just over half of participants with hypertension aware of their diagnosis, and about one-third of those being treated for hypertension successfully controlling their blood pressure, according to a study in the September 4 issue of JAMA. "High blood pressure is the leading cause of cardiovascular disease (CVD) and deaths globally. It is associated with at least ...

A study based on a nationally representative sample of adults in China in 2010 indicates that nearly 12 percent of Chinese adults had diabetes and the prevalence of prediabetes was about 50 percent, according to a study in the September 4 issue of JAMA. "Noncommunicable chronic diseases have become the leading causes of mortality and disease burden worldwide. It was estimated that 34.5 million deaths globally were due to noncommunicable diseases in 2010, which reflected a significant increase from 1990. Mortality from diabetes doubled during this period and increased ...

The use of 4 different 13-valent pneumococcal conjugate vaccine immunization schedules in healthy term infants resulted in no statistically significant differences in antibody levels between the infants after the booster dose at 12 months of age for almost all serotypes, according to a study in the September 4 issue of JAMA. "The World Health Organization (WHO) estimated that more than 800,000 children younger than 5 years died from pneumococcal disease in 2000, making it the leading vaccine-preventable cause of death. Since the licensure in 2000 of the first 7-valent ...

Children in a malaria-endemic community in Ghana who received a micronutrient powder with iron did not have an increased incidence of malaria, according to a study in the September 4 issue of JAMA. Previous research has suggested that iron supplementation for children with iron deficiency in malaria-endemic areas may increase the risk of malaria. "In sub-Saharan Africa, malaria is a leading cause of childhood morbidity and mortality, and iron deficiency is among the most prevalent preventable nutritional deficiencies. The provision of iron to children with iron deficiency ...

"Hepatitis B virus (HBV) infection causes infant fulminant hepatitis (IFH), and chronic HBV infection may progress to chronic liver disease (CLD) and hepatocellular carcinoma (HCC). Taiwan launched a nationwide HBV immunization program for newborns in July 1984, which has successfully lowered the prevalence of chronic HBV carriers, incidence of HCC, and mortality of IFH in vaccinated birth cohorts. The mortality of CLD before and after HBV immunization has never been examined," write Chun-Ju Chiang, Ph.D., of National Taiwan University, Taipei, and colleagues. As reported ...

Washington, DC — Sleep increases the reproduction of the cells that go on to form the insulating material on nerve cell projections in the brain and spinal cord known as myelin, according to an animal study published in the September 4 issue of The Journal of Neuroscience. The findings could one day lead scientists to new insights about sleep's role in brain repair and growth. Scientists have known for years that many genes are turned on during sleep and off during periods of wakefulness. However, it was unclear how sleep affects specific cells types, such as oligodendrocytes, ...

The use of whole bacterial genome sequencing will allow scientists to inexpensively track how bovine tuberculosis (TB) is transmitted from farm to farm, according to research presented this week at the Society of General Microbiology Autumn Conference. Bovine TB is primarily a disease of cattle, caused by the bacterium Mycobacterium bovis. The disease is hugely expensive, costing the Government over £91 million in England in 2010/11. Researchers from the University of Glasgow, working in collaboration with the Agri-Food and Biosciences Institute and the Department ...

People are much more likely to take preventive medicines if they're combined in one pill, an international study has found. The findings are published today in the Journal of the American Medical Association. Taking aspirin, cholesterol-lowering and blood pressure-lowering drugs long-term more than halves heart attack and stroke recurrence. However, only about 50 per cent of people with cardiovascular disease in high-income countries take all recommended preventive medications. In low- and middle-income countries, only five to 20 per cent do. This leaves tens of millions ...

A study of around 5,000 older men has shown that stressful life events such as death of a loved one, or serious financial problems, significantly raised the risk of falls in the year following the incident. The research is published online today in the journal Age and Ageing. Dr Howard A. Fink of the VA Medical Center in Minneapolis and colleagues conducted a study of 5,994 community-dwelling men over the age of 65 who were enrolled in the Osteoporotic Fractures in Men (MrOS) study in six locations across the United States. 5,125 participated in a second study visit ...

DURHAM, N.C. -- During a normal conversation, your brain is constantly adjusting the volume to soften the sound of your own voice and boost the voices of others in the room. This ability to distinguish between the sounds generated from your own movements and those coming from the outside world is important not only for catching up on water cooler gossip, but also for learning how to speak or play a musical instrument. Now, researchers have developed the first diagram of the brain circuitry that enables this complex interplay between the motor system and the auditory ...

New research from the University of East Anglia has shown that females can maximise the genetic quality of their offspring by being promiscuous. Researchers studied red junglefowl (the wild ancestor of the domestic chicken) in a collaborative project with the University of Oxford, Stockholm University and Linköping University. Findings published today in the journal Proceedings of the Royal Society B reveal that mating with different males helps females produce offspring that are more resistant to diseases. This is down to 'cryptic female choice' -- where an internal ...

Frontiers in Physiology Not a bat choice: echolocation works better than eyesight, even under adequate light A new study in Frontiers in Physiology shows for the first time that bats catch insects by sonar as it is far more efficient than using vision, even during twilight. Bats have eyes and may not have evolved their ultrasonic sonar from the earliest time of their existence on earth. Approximately 1000 species of bats use sonar to detect prey, despite showing considerable variation in the preferred size of their prey and their mode of hunting. But why? Many bats ...

Electronic devices with touchscreens are ubiquitous, and one key piece of technology makes them possible: transparent conductors. However, the cost and the physical limitations of the material these conductors are usually made of are hampering progress toward flexible touchscreen devices. Fortunately, a research collaboration between the University of Pennsylvania and Duke University has shown a new a way to design transparent conductors using metal nanowires that could enable less expensive — and flexible — touchscreens. The research was conducted by graduate student ...

A visible image of Tropical Storm Toraji was captured on Sept. 3 at 02:10 UTC/Sept. 2 at 10:10 p.m. is it continued moving north past eastern China and approached southern Japan. The image was taken by the Moderate Resolution Imaging Spectroradiometer or MODIS instrument that flies aboard NASA's Terra satellite. The image showed strong thunderstorms wrapped around the center of the tropical storm. Bands of thunderstorms wrapping into the center from the north extended over Kyushu. Kyushu is the third largest island of Japan and is farthest southwest of Japan's four main ...

A lot of things happen over a holiday weekend, and while people in the United States were celebrating Labor Day weekend, the Eastern Pacific Ocean's Tropical Storm Kiko came and went. Satellite data captured Tropical Storm Kiko's birth on Sept. 1 and saw its remnants weakening on Sept. 3. As Kiko dissipates, another low pressure system is forming near the southwestern coast of Mexico. NOAA's GOES-West satellite captured the life of Kiko from the time it became Tropical Depression 11 on Aug. 31. The depression formed about 500 miles/805 km west-southwest of the southern ...

WINSTON-SALEM, N.C. – Sept. 3, 2013 – Low-income communities have particular problems getting adequate fruits and vegetables because of limited access to supermarkets and farmers markets. A new study from Wake Forest Baptist Medical Center shows that community-supported agriculture (CSA) programs may be a feasible approach for providing fresh fruits and vegetables to under-resourced communities. Lead author Sara A. Quandt, Ph.D., a professor of epidemiology and prevention at Wake Forest Baptist, said that CSAs, which link consumers to a local farm's produce over a growing ...

LA JOLLA, CA----Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are replaced with new functional copies. In a new study published August 29 in Cell, a team led by researchers at the Salk Institute for Biological Studies and The Scripps Research Institute (TSRI) have now identified a small subset of proteins in the brain that persist for longer, even more than a year, without being replaced. These long-lived ...

Fires burned throughout Bolivia in late August. The Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA's Aqua satellite captured this natural-color image on August 31, 2013. Red outlines indicate areas where MODIS has detected high surface temperatures associated with actively burning fires. In many places, the smoke from these blazes is thick enough to completely hide the land surface below from the satellite sensor's view. In general, the smoke plumes blow toward the west and northwest. Wildfires can occur naturally in Bolivia, but the widespread burning ...

ROCHESTER, Minn. -- Mayo Clinic researchers have found a way to resynchronize cardiac motion following a heart attack using stem cells. Scientists implanted engineered stem cells, also known as induced pluripotent stem (iPS) cells, into damaged regions of mouse hearts following a heart attack. This regenerative approach successfully targeted the origin of abnormal cardiac motion, preventing heart failure. The findings appear in the September issue of the Journal of Physiology. MULTIMEDIA ALERT: Video resources, including interviews with Drs. Terzic and Yamada, are available ...

FORENSICS – Mass grave detection . . . Families of thousands of victims of social violence may gain closure, and killers may receive appropriate punishment, because of a suite of technologies able to locate clandestine graves. While investigators can find some graves, perhaps hundreds of thousands remain undiscovered. Researchers at the University of Tennessee's Forensic Anthropology Center and Oak Ridge National Laboratory are developing a method to discover graves using sensors, onboard satellites and unmanned aerial vehicles. [Contact: Ron Walli, (865) 576-0226; wallira@ornl.gov] BIOENERGY ...

(Boston) - Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have found that among obese people who had lost considerable weight, those with high insulin levels--a marker of insulin resistance in the body--were the most likely to experience better blood vessel function following the weight loss. These findings appear online in the Journal of the American College of Cardiology. Obesity has emerged as one of the most critical health care problems in the U.S. and worldwide with nearly 70 percent of the U.S. population currently ...

Big global questions face us, among them: How will we feed a growing global population without ruining the soil and polluting freshwater? Or meet our burgeoning energy demands while curbing the greenhouse gas emissions that fuel rising sea levels, flooding, drought, disease and wildfire? And what can we do to stem the extinction of thousands of other species that share the planet with us? These daunting "environmental" problems are not only in the domain of ecologists and environmental scientists. Other natural scientists, social, behavioral and economic researchers, ...

September 3, 203 - Any parent will tell you that there is no simple recipe for raising a child. Being a parent means getting hefty doses of advice – often unsolicited – from others. But such advice often fails to consider a critical factor: the child. A new review of dozens of studies involving more than 14,600 pairs of twins shows that children's genetics significantly affect how they are parented. "There is a lot of pressure on parents these days to produce children that excel in everything, socially and academically," says Reut Avinun of the Hebrew University of Jerusalem. ...

West Orange, NJ. August 30, 2013. The September issue of the Journal of Spinal Cord Medicine focuses on, "The Changing Face of Spinal Cord Injury," the theme for the 2013 meeting of the Academy of Spinal Cord Injury (SCI) Professionals. Research articles address topics in urology, neuroscience, rehabilitation psychology, physiology, gastroenterology, and infectious disease. The conference dates are September 2-4 at Bally's Hotel in Las Vegas, Nevada. Conference abstracts are available for free download at: http://tinyurl.com/n95jnoy The issue's lead article is a state-of-the-art ...